Assessment of the Effect of Casein Phosphopeptide–amorphous Calcium Phosphate on Postoperative Sensitivity Associated With In-office Vital Tooth Whitening

2014 ◽  
Vol 39 (3) ◽  
pp. 239-247 ◽  
Author(s):  
GA Maghaireh ◽  
H Alzraikat ◽  
A Guidoum
Keyword(s):  
Calcium Phosphate ◽  
Amorphous Calcium Phosphate ◽  
Daily Basis ◽  
The Other ◽  
Intensity Level ◽  
Tooth Whitening ◽  
Tooth Sensitivity ◽  
Therapeutic Benefits ◽  
Casein Phosphopeptide

SUMMARY The aim of this study was to evaluate the efficacy of tooth mousse containing 10% casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) in reducing tooth sensitivity associated with in-office vital tooth whitening. In-office tooth whitening was performed for 51 participants using 35% hydrogen peroxide gel in a single visit. After the procedure, each participant was randomly assigned to one of three groups: gel without desensitizing agent (n=17), gel with 2% sodium fluoride (n=17), gel with 10% CPP-ACP (n=17). A small amount of the desensitizing gel assigned for each participant was applied directly on the labial surfaces of teeth and left undisturbed for three minutes. The participants were asked to apply the gel assigned to them for three minutes twice daily after brushing their teeth, and to continue this for 14 days. The participants were asked to return for follow-up visits after 24 hours and on days 3, 7, and 14, at which time teeth shade changes were assessed by one evaluator using a value-oriented Vita classic shade guide. The incidence, duration, and intensity of tooth sensitivity experienced was self-assessed on a daily basis for the 14-day study period using a visual analog scale (VAS). The effect of the three gels on tooth sensitivity was assessed using one-way analysis of variance and a χ2 test (α=0.05). The general linear model was used to compare intensity-level differences in the three studied groups and for shade stability over the follow-up period. The results of this study showed that all three gels decreased the intensity of sensitivity associated with tooth whitening. The intensity of sensitivity was lower in the fluoride group than in the other two groups; however, it was not statistically significant (p=0.112 and p=0.532 on day 1 and day 2, respectively). The average shade change was 6.8. None of the tested materials affected the efficacy of tooth whitening, but the shade change among the fluoride group showed more color stability than that of the other two groups. This study suggested that using a gel after tooth whitening can reduce the intensity of tooth sensitivity associated with in-office whitening procedures without affecting the efficiency of tooth whitening. However, it failed to demonstrate that using a 10% CPP-ACP could provide additional therapeutic benefits.

scholarly journals Effect of Casein Phosphopeptide–Amorphous Calcium Phosphate on Fracture Resistance of Reattached Tooth Fragments Using Conventional and Self-Adhesive Bioactive Flowable Composite

2020 ◽  
Vol 14 (02) ◽  
pp. 288-293
Author(s):  
Maryam Firouzmandi ◽  
Neda Afzali ◽  
Zahra Parsaie ◽  
Najmeh Mohammadi
Keyword(s):  
Calcium Phosphate ◽  
Amorphous Calcium Phosphate ◽  
Fracture Resistance ◽  
Testing Machine ◽  
Selective Etching ◽  
The Other ◽  
Flowable Composite ◽  
Group 2 ◽  
Casein Phosphopeptide

Abstract Objectives The present study aimed to investigate the effect of casein phosphopeptide–amorphous calcium phosphate (CPP-ACP) complex and the type of flowable composite (conventional or self-adhesive bioactive) on the fracture resistance of fractured incisors restored through reattachment technique. Materials and Methods In this experimental in vitro study, 60 extracted bovine central mandibular incisors were randomly divided into six groups (n = 10) according to the reattachment technique. Their incisal edges were cut off to represent an enamel–dentin fracture. The fragment edges were reattached as follows: Group 1—selective etching and bonding followed by conventional flowable composite; Group 2—selective etching and bonding followed by bioactive flowable composite; Group 3 was like Group 2 but without applying bonding; Groups 4, 5, and 6 were similar to Groups 1, 2, and 3, respectively, but both tooth fragments were pretreated with CPP-ACP-containing paste for 3 minutes. Fracture resistance was assessed by a universal testing machine. Statistical Analysis Data were analyzed by SPSS—Statistical Package for the Social Sciences—software using one-way analysis of variance and Tukey post-hoc tests (α= 0.05). Results The highest and lowest fracture resistance was recorded in Groups 5 (15.96 MPa) and Group 6 (1.95 MPa), respectively, being significantly different from the other groups. The mean fracture resistance of Groups 3 and 6 was significantly lower than the other groups (p < 0.05). However, Groups 1, 2, and 4 showed no difference in fracture resistance. Conclusion Bioactive composite was not superior to conventional composite for fragment reattachment, but using it in self-adhesive mode reduced the fracture strength significantly. Yet, pretreatment with CPP-ACP, followed by application of adhesive, improved the fracture resistance of bioactive composite.

scholarly journals Reversal of Root Caries with Casein Phosphopeptide-Amorphous Calcium Phosphate and Fluoride Varnish in Xerostomia

2021 ◽  
pp. 1-10
Author(s):  
Ahmed Sleibi ◽  
Anwar R. Tappuni ◽  
Aylin Baysan
Keyword(s):  
Calcium Phosphate ◽  
Amorphous Calcium Phosphate ◽  
Primary Root ◽  
Severity Index ◽  
Salivary Flow ◽  
Root Caries ◽  
Carious Lesions ◽  
Group 2 ◽  
Casein Phosphopeptide ◽  
Group 1

Different formulas of topical fluoride have been used to manage root carious lesions. This clinical trial aimed to investigate the efficacy of a dental varnish containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride compared with fluoride alone in reversing/arresting root caries in xerostomic patients over 1 year. A total of 80 patients (age range 45–92 years) with primary root caries (<i>n</i> = 184 root carious lesions) and unstimulated salivary flow rate of &#x3c;0.2 mL/min were randomly allocated to receive either dental varnish containing CPP-ACP and 5% fluoride (group 1: MI varnish; GC, Japan) (<i>n</i> = 41, 83 lesions), or dental varnish with 5% fluoride alone (group 2: NUPRO White; Dentsply, USA) (<i>n</i> = 39, 101 lesions). Clinical assessments with Severity Index (SI) for root caries, DIAGNOdent measurements, and varnish application were carried out at baseline, 3, 6, and 12 months. Standard oral hygiene instructions with 1,450 ppm fluoride toothpastes were provided for both groups. After 3 months, 63.9% (<i>n</i> = 46) of root caries in group 1 became hard (SI: 0) compared with 39.3% (<i>n</i> = 35) in group 2 (<i>p</i> &#x3c; 0.01). After 6 and 12 months, the differences in SI were insignificant (group 1, <i>n</i> = 60, 83.3%) (group 2, <i>n</i> = 66, 74.2%) (<i>p</i> = 0.36), and (group 1, <i>n</i> = 60, 89.6%) (group 2, <i>n</i> = 67, 81.7%, <i>n</i> = 1 soft, 1.2%) (<i>p</i> = 0.29), respectively. In both groups, noncavitated leathery lesions were more likely to become hard when compared to the cavitated root caries. A significant decrease in plaque index, surface roughness, lesion dimension, and DIAGNOdent readings with a significant increase in lesion distance from the gingival margin was reported in both groups (<i>p</i> &#x3c; 0.05). This study has provided evidence that fluoride dental varnish either with or without calcium and phosphate has the potential to arrest/reverse root caries, especially noncavitated lesions for patients with xerostomia.

Casein phosphopeptide–amorphous calcium phosphate fluoride treatment enriches the symbiotic dental plaque microbiome in children

2021 ◽  
Vol 106 ◽  
pp. 103582
Author(s):  
Armelia Sari Widyarman ◽  
Nadeeka S. Udawatte ◽  
Citra Fragrantia Theodorea ◽  
Anie Apriani ◽  
Mario Richi ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Amorphous Calcium Phosphate ◽  
Dental Plaque ◽  
Fluoride Treatment ◽  
Casein Phosphopeptide

scholarly journals Consumption of milk with added casein phosphopeptide-amorphous calcium phosphate remineralizes enamel subsurface lesionsin situ

2009 ◽  
Vol 54 (3) ◽  
pp. 245-249 ◽  
Author(s):  
GD Walker ◽  
F Cai ◽  
P Shen ◽  
DL Bailey ◽  
Y Yuan ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Amorphous Calcium Phosphate ◽  
Casein Phosphopeptide

Efficacy of in-office bleaching techniques combined with the application of a casein phosphopeptide-amorphous calcium phosphate paste at different moments and its influence on enamel surface properties

2012 ◽  
Vol 75 (8) ◽  
pp. 1019-1025 ◽  
Author(s):  
Ana Gabriela Gama Cunha ◽  
Adriana Alcantara Meira De Vasconcelos ◽  
Boniek Castillo Dutra Borges ◽  
Jussier De Oliveira Vitoriano ◽  
Clodomiro Alves-Junior ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Surface Properties ◽  
Amorphous Calcium Phosphate ◽  
Enamel Surface ◽  
Casein Phosphopeptide

scholarly journals Evaluation of metallic brackets adhesion after the use of bleaching gels with and without amorphous calcium phosphate (ACP): in vitro study

2013 ◽  
Vol 18 (3) ◽  
pp. 101-106 ◽  
Author(s):  
Sissy Maria Mendes Machado ◽  
Diego Bruno Pinho do Nascimento ◽  
Robson Costa Silva ◽  
Sandro Cordeiro Loretto ◽  
David Normando
Keyword(s):  
Calcium Phosphate ◽  
Bond Strength ◽  
Amorphous Calcium Phosphate ◽  
Shear Bond Strength ◽  
Mechanical Test ◽  
In Vitro Study ◽  
Control Group ◽  
Test Machine ◽  
Tooth Whitening

OBJECTIVE: To evaluate in vitro the effects of tooth whitening using gel with Amorphous Calcium Phosphate (ACP) on the bond strength of metal brackets. METHODS: Thirty-six bovine incisors were sectioned at the crown-root interface, and the crowns were then placed in PVC cylinders. The specimens were divided into 3 groups (n = 12) according to whitening treatment and type of gel used, as follows: G1 (control) = no whitening; G2 = whitening with gel not containing ACP (Whiteness Perfect - FGM), G3 = whitening with gel containing ACP (Nite White ACP - Discus Dental). Groups G2 and G3 were subjected to 14 cycles of whitening followed by an interval of 15 days before the bonding of metal brackets. Shear bond strength testing was performed on a Kratos universal test machine at a speed of 0.5 mm/min. After the mechanical test, the specimens were assessed to determine the adhesive remnant index (ARI). The results were subjected to ANOVA, Tukey's test and Kruskal-Wallis test (5%). RESULTS: Significant differences were noted between the groups. Control group (G1 = 11.10 MPa) showed a statistically higher shear bond strength than the groups that underwent whitening (G2 = 5.40 Mpa, G3 = 3.73 MPa), which did not differ from each other. There were no significant differences between the groups in terms of ARI. CONCLUSION: Tooth whitening reduces the bond strength of metal brackets, whereas the presence of ACP in the whitening gel has no bearing on the results.

scholarly journals Biocompatibility and Osteogenic/Calcification Potential of Casein Phosphopeptide-amorphous Calcium Phosphate Fluoride

2018 ◽  
Vol 44 (3) ◽  
pp. 452-457 ◽  
Author(s):  
Alaa E. Dawood ◽  
David J. Manton ◽  
Peter Parashos ◽  
Rebecca H. Wong ◽  
William Singleton ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Amorphous Calcium Phosphate ◽  
Casein Phosphopeptide

scholarly journals Casein Phosphopeptide-Amorphous Calcium Phosphate Reduces Streptococcus mutans Biofilm Development on Glass Ionomer Cement and Disrupts Established Biofilms

PLoS ONE ◽  
2016 ◽  
Vol 11 (9) ◽  
pp. e0162322 ◽  
Author(s):  
Stuart G. Dashper ◽  
Deanne V. Catmull ◽  
Sze-Wei Liu ◽  
Helen Myroforidis ◽  
Ilya Zalizniak ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Streptococcus Mutans ◽  
Amorphous Calcium Phosphate ◽  
Glass Ionomer Cement ◽  
Glass Ionomer ◽  
Casein Phosphopeptide ◽  
Biofilm Development ◽  
Ionomer Cement
Sign in / Sign up

Export Citation Format

Share Document