Dentin Staining Caused by Nano-silver Fluoride: A Comparative Study

2019 ◽  
Vol 45 (4) ◽  
pp. 435-441
Author(s):  
LF Espíndola-Castro ◽  
A Rosenblatt ◽  
A Galembeck ◽  
GQM Monteiro

Clinical Relevance The new formulations of nano-silver fluoride caused less dentin staining than the already available commercial agents 35% silver fluoride and silver diamine fluoride at 30% and 38%. SUMMARY The objective of this study was to evaluate the dentin staining potential of nano-silver fluoride (NSF 600 and 1500 ppm) compared with the following commercially available cariostatic agents: Advantage Arrest (Elevate Oral Care, West Palm Beach, FL, USA), Riva Star (SDI, Victoria, Australia), and Cariestop (Biodinâmica, Paraná, Brazil). Seventy-five extracted human molars were sectioned at the cementoenamel junction, and the occlusal enamel was removed for exposure of coronary dentin. The samples were divided among the five agents tested (n=15). The dentin staining (ΔE/ΔL) was analyzed with a digital spectrophotometer (VITA Easyshade, VITA Zahnfabrik, Bad Säckingen, Germany) at three different time points (before application, after two weeks, and after four weeks). Photographic images were also performed. The Kruskal-Wallis and Mann-Whitney tests compared the mean ΔE and ΔL values between groups. The NSF 600 and 1500 ppm resulted in the smallest color change (ΔE=1.02 and 1.53) and dentin staining after four weeks (ΔL=−0.76 and −1.2). The new formulations differed significantly from the commercial cariostatic agents (p<0.001). NSF might be an alternative to silver diamine fluoride since it does not compromise esthetics.

2018 ◽  
Vol 9 ◽  
pp. 51 ◽  
Author(s):  
Sri Angky Soekanto ◽  
Levy Jeremy Marpaung ◽  
Himmat Ushohwah ◽  
Ariadna Djais ◽  
Risqa Rina Darwita

Objective: The objective of this study is to investigate the potency of propolis fluoride (PPF) and nano silver fluoride (NSF) as fluoride-based varnishes for inhibiting Streptococcus mutans and Enterococcus faecalis biofilm formation. In this study, both varnishes were compared to silver diamine fluoride (SDF) varnish, the gold standard for anticariogenic agents.Methods: The suspensions of S. mutans and E. faecalis were cultured and then plated into 96 - well plates and combined with SDF (38%), NSF (3.16, 3.66, and 4.16%), or PPF (3, 6, and 10%). E. faecalis was incubated in an anaerobic environment for 24 h, and the same protocol was used for S. mutans. The amount of biofilm inhibition was evaluated by optical density measurements at 570 nm using a microplate reader. Data were analyzed using one-way ANOVA.Results: The minimum inhibitory concentration (MIC) of PPF for S. mutans was 3%, and minimum bactericidal concentration (MBC) was 10%. The MIC of PPF for E. faecalis was at 6%, but no MBC was established. The MIC of NSF for S. mutans was 3.16%, and the MBC was 4.16%. The MIC of NSF for E. faecalis was 3.16%, while the MBC was 4.16%. Biofilm formation was inhibited dose-dependently by both NSF and PPF.Conclusion: NSF and PPF fluoride-based varnishes show clear antibacterial effects that are comparable to those obtained with SDF fluoride-based varnish.


Author(s):  
Pranav Madhav Kuber ◽  
Ehsan Rashedi

A new forklift backrest has been developed by incorporating adjustability concepts into the design to facilitate comfort to a wide range of users. We have conducted a comparative study between the new and original backrests to assess the effectiveness of design features. Using the phenomenon of restlessness, discomfort of the user was associated with the amount of body movement, where we have used a motion- capture system and a force platform to quantify the individuals’ movement for a wide range of body sizes. Meanwhile, subjective comfort and design feedback were collected using a questionnaire. Our results showed a reduction in the mean torso movement and the maximum center of pressure change of location by 300 and 6 mm, respectively, for the new design. Taking advantage of adjustability feature, the new backrest design exhibited enhanced comfort for longer durations and reduced magnitude of discomfort for a wide range of participants’ body sizes.


2020 ◽  
Vol 41 (S1) ◽  
pp. s348-s349
Author(s):  
Hajime Kanamori ◽  
William Rutala ◽  
Maria Gergen ◽  
David Jay Weber

Background: The contaminated healthcare environment, including operating rooms (ORs), can serve as an important role in transmission of healthcare-associated pathogens. Studies are very limited regarding the level of contamination of ORs during the surgery of a patient on contact precautions and the risk to the next surgery patient after standard room cleaning and disinfection. Objective: Here, we investigated the microbial burden on the OR environment when patients on contact precautions receive surgery, and we assessed the impact of cleaning and disinfection on the contamination of OR environmental sites. Methods: This investigation was conducted in the ORs of an academic facility during an 8-month period. It involved 10 patients on contact precautions for multidrug-resistant pathogens, including methicillin-resistant Staphylococcus aureus (MRSA; n = 7); carbapenem-resistant Enterobacteriaceae (CRE) plus MRSA (n = 2); and vancomycin-resistant Enterococcus (VRE) plus MRSA (n = 1), who underwent surgery. Environmental sampling was performed at the following time points: (1) immediately before the surgical patient’s arrival in the OR, (2) after surgery but before the OR cleaning and disinfection, and (3) after the OR cleaning and disinfection. In total, 1,520 environmental samples collected from 15 OR sites for 10 surgical patients at 3 time points were analyzed. Relatedness among environmental MRSA isolates was determined by pulsed-field gel electrophoresis. Results: Overall, the mean CFUs of aerobes per Rodac plate (CFU/25 cm2) were 10.1 before patient arrival, 14.7 before cleaning and disinfection, and 6.3 after cleaning and disinfection (P < .0001, after cleaning and disinfection vs before cleaning and disinfection). Moreover, 7 environmental sites (46.7%) after cleaning and disinfection, including bed, arm rest, pyxis counter, floor (near, door side), floor (far, by door), steel counter (small, near bed), and small computer desk, had significantly lower mean counts of aerobes than before patient arrival or before cleaning and disinfection (Fig. 1). The mean CFUs of MRSA per Rodac plate (CFU/25 cm2) were 0.04 before patient arrival, 0.66 before cleaning and disinfection, and 0.08 after cleaning and disinfection (P = .0006, after cleaning and disinfection vs before cleaning and disinfection). Of environmental sites where MRSA was identified, 87.2% were on floors (41 of 47) and 19.1% were after cleaning and disinfection (9 of 47, 8 from floors and 1 from pyxis touchscreen). The A2/B2 MRSA strain was identified on different environmental sites (eg, floor, computer desk, counter) in various rooms (eg, OR2, OR10, and OR16), even after cleaning and disinfection (Fig. 2). Conclusions: Our study has demonstrated that the OR environment was contaminated with aerobic bacteria and MRSA after surgery and that MRSA persisted in the environment even after cleaning and disinfection. Enhanced environmental cleaning in the perioperative environment used for patients on isolation is necessary to prevent transmission of healthcare-associated pathogens in ORs.Funding: NoneDisclosures: Drs. Rutala and Weber are consultants to PDI (Professional Disposable International)


2021 ◽  
Vol 8 (41) ◽  
pp. 3559-3566
Author(s):  
Abdul Salam R. T. ◽  
Shahul Hameed A. ◽  
Meera Rajan

BACKGROUND An ideal surgery to remove hypertrophied adenoid mass should be safe, with less bleeding and operation time along with post-operative improvement in the eustachian tubal ventilation and normal respiration. It should also have low morbidity and mortality. Among the various methods described for its removal, the two commonly used methods are conventional cold curettage method and coblation technique. The purpose of this study was to collate the safety and efficacy of endoscopic coblation adenoidectomy with the conventional curettage adenoidectomy. METHODS A prospective comparative study with fifty patients was studied who underwent adenoidectomy. Twenty five patients underwent endoscopy assisted coblation adenoidectomy and twenty five patients underwent regular adenoidectomy by curettage. RESULTS Patients who underwent coblation adenoidectomy showed better results during follow up in terms of completeness of removal. 80 % of children undergoing regular adenoidectomy by curettage method showed remnant adenoid tissue in the nasopharynx at the end of the procedure. But it was 6 % among the children undergoing endoscopic assisted coblation adenoidectomy. The mean duration of operation was higher for endoscopic assisted coblation adenoidectomy which was significant statistically. The mean blood loss was 30.36 ml in regular curettage adenoidectomy; 10.6 ml with endoscopic coblation adenoidectomy. The grading of pain was significantly lower in endoscopic assisted coblation adenoidectomy. There was no significant difference between two groups in terms of eustachian tube function after surgery. CONCLUSIONS Coblation adenoidectomy has significant advantages over conventional adenoidectomy in terms of completeness of removal, reduced blood loss, and lower post-operative pain grade. KEYWORDS Coblation, Adenoidectomy, Curettage, Haemorrhage and Complications


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