scholarly journals Intra-Operative Findings in Middle Ear Cleft in Cases of Chronic Inactive Mucosal Otitis Media

2020 ◽  
Vol 6 (4) ◽  
Author(s):  
Chakraborty Sourabh Shankar ◽  
Monga Anil K
2021 ◽  
Vol 15 (6) ◽  
pp. 1426-1428
Author(s):  
W. Javaid ◽  
A. Rashid ◽  
M. U. K. Amin ◽  
T. Khan ◽  
M. Fatima

Background: Cholesteotoma is a benign but destructive lesion leading to ossicular necrosis. Objective: To see the frequency of incus bone erosion on mastoid exploration in chronic suppurative otitis media with middle ear cholesteotoma. Study Design: Cross-sectional descriptive study. Setting: This study was carried out in the Department of ENT Unit-2, Sir Ganga Ram Hospital, Lahore. Duration of Study: Fifteen months months (10th April, 2019 to 9th July, 2020) Sample technique: Non- probability purposive sampling Methods: One hundred and twenty patients were admitted through outpatient department of ENT Unit-2, Sir Ganga Ram Hospital Lahore. Patients were included after fulfilling the inclusion criteria and information was collected on a prescribed proforma. Finally during surgery under general anesthesia, the operative findings were noted to know the incus bone erosion after middle ear cholesteatoma formation in chronic suppurative otitis media. Results: A total number of one hundred and twenty patients of chronic suppurative otitis media with middle ear cholesteatoma were included. Out of which 80 (66.7%) were males and 40 (33.3%) were females(Table 1).The patients shown in table 2 were divided in six age groups (Table 2).Table 3 shows that the procedure of mastoidectomy was performed in 112 patients (93.3%) and modified radial mastoidectomy was performed in 8 patients (6.7%).Incus bone erosion in chronic suppurative otitis media with middle ear cholesteatoma in 102 patients (85%) and 18 patients (15%) have no incus bone erosion (Table 4). Conclusion: Ear discharge was the most common presenting characteristic of chronic suppurative otitis media with cholesteatoma. The majority of the cases had ossicular erosion, with the incus being the most common site of involvement. Males are more likely than females to develop cholesteatoma. Keywords: erosion of incus bone, Mastoid exploration, Chronic suppurative otitis media, Cholesteatoma


2015 ◽  
Vol 23 (3) ◽  
pp. 116-119
Author(s):  
Somesh Mozumder ◽  
Arunabha Sengupta ◽  
Alok Ranjan Mondal ◽  
Soumik Basu

Introduction: Chronic otitis media is a long standing infection of part or whole of middle ear cleft. Its active squamosal variant (cholesteatoma) is most dangerous due to its bone eroding property. Aims & Objective: Background knowledge of ossicular status in cholesteatoma  will help us in determining the type  of reconstruction needed during the surgery. Material & methods: 60 cases of cholesteama, irrespective of age and sex [diagnosed on the basis of clinical examination , audiological and radiological evaluation] were selected during the study period of two years and their ossicular status were recorded intra-operatively. Results &  analysis: Ossicles and their parts getting involved in cholesteatoma cases , in decreasing order are : Lenticular process (in total 50 cases)>Long process of incus (in total 49 cases) > stapes super-structure(in total 29 cases) > body of incus(in total 26 cases)> head of malleus(in total 23 cases)> handle of malleus(in total 10 cases). Ossicular chain  defeact in decreasing order are : M-I-S- > M+I-S- > M-I-S+ > M+I-S+. Conclusion: In our study it was found that incus is the most vulnerable ossicle to get involved in cases of active squamosal variety of chronic otitis media where as malleus appeared to be the least susceptible one.


2018 ◽  
Vol 26 (1) ◽  
pp. 43-47
Author(s):  
Santosh U P ◽  
Sridurga J ◽  
Aravind D R

Introduction             Chronic otitis media (COM) is a most common and prevalent disease of the middle ear. COM has been defined as a longstanding inflammatory condition of middle ear and mastoid, associated with perforation of the tympanic membrane. Tympanoplasties are common surgeries performed for chronic otitis media in inactive mucosal type. Any otological surgery may involve a menace/ hazard of hearing loss post operatively.             In this study, an attempt was made to correlate, size of tympanic membrane perforation, pure tone audiometry and intra-operative findings in tympanoplasties, results were analysed and conclusion drawn. Materials and Methods Forty patients attending ENT OPD with chronic otitis media (COM), inactive mucosal type, with conductive hearing loss undergoing tympanoplasties who were willing to participate in the study were selected.  Ear was examined pre-operatively to assess the size of perforation and then, pure tone audiometry (PTA) was done to assess the type of hearing loss and its severity. During tympanoplasty, middle ear was inspected for ossicular status and any other pathology was noted. Later, the size of tympanic membrane perforation, pure tone audiometry and intra operative findings were correlated with each other and analysed. Result  In small and medium sized perforation, PTA and intraoperative findings correlated with each other. Whereas, in large and subtotal perforation, there was no correlation. Conclusion             In small and medium sized perforation, middle ear inspection may not be necessary. Whereas, in large and subtotal perforation it is necessary. 


1976 ◽  
Vol 85 (2_suppl) ◽  
pp. 90-96 ◽  
Author(s):  
Joel M. Bernstein

Four biological mediators of inflammation have been found in middle ear effusions from patients with otitis media with effusion. They are chemotactic factor(s), macrophage inhibition factor(s), activated complement and prostaglandins. The potential role of these mediators has been discussed in relation to their potential for maintaining inflammation in the middle ear cleft after Eustachian tube dysfunction.


2000 ◽  
Vol 68 (2) ◽  
pp. 921-924 ◽  
Author(s):  
H. H. Tong ◽  
L. E. Blue ◽  
M. A. James ◽  
T. F. DeMaria

ABSTRACT Considerable evidence has implicated Streptococcus pneumoniae neuraminidase in the pathogenesis of otitis media (OM); however, its exact role has not been conclusively established. Recently, an S. pneumoniae neuraminidase-deficient mutant, ΔNA1, has been constructed by insertion-duplication mutagenesis of the nanA gene of S. pneumoniae strain D39. The relative ability of ΔNA1 and the D39 parent strain to colonize the nasopharynx and to induce OM subsequent to intranasal inoculation and to survive in the middle ear cleft after direct challenge of the middle ear were evaluated in the chinchilla model. Nasopharyngeal colonization data indicate a significant difference in the ability of the ΔNA1 mutant to colonize as well as to persist in the nasopharynx. The neuraminidase-deficient mutant was eliminated from the nasopharynx 2 weeks earlier than the D39 parent strain. Both the parent and the mutant exhibited similar virulence levels and kinetics during the first week after direct inoculation of the middle ear. The ΔNA1 neuraminidase-deficient mutant, however, was then completely eliminated from the middle ear by day 10 postchallenge, 11 days before the D39 parent strain. Data from this study indicate that products of thenanA gene have an impact on the ability of S. pneumoniae to colonize and persist in the nasopharynx as well as the middle ear.


1994 ◽  
Vol 103 (3) ◽  
pp. 227-234 ◽  
Author(s):  
Shin-Ichi Sano ◽  
Shin-Ichi Haruna ◽  
Patricia A. Schachern ◽  
Michael M. Paparella

We describe the cytokeratin patterns of epithelia from the tympanic orifice, tympanic cavity, and mastoid cavity of humans, cats, and chinchillas, and compare these findings with those of tracheal epithelium and external canal epidermis. Our findings are as follows: 1) middle ear epithelium from all locations demonstrates some type of cytokeratin staining, 2) broad-spectrum cytokeratin antibodies stain epithelia of middle ear cleft, tracheal epithelium, and external canal epidermis in all species, 3) specific cytokeratin antibodies reveal species-related differences in middle ear and tracheal epithelia, 4) middle ear and tracheal epithelia usually have the same pattern, and 5) none of the monospecific cytokeratin antibodies have a positive reaction with external canal epidermis. These findings suggest that the cytokeratin patterns of middle ear epithelium are useful in studying the hyperplastic and metaplastic changes in otitis media; however, caution must be exercised when making interspecies comparisons.


2020 ◽  
Vol 27 (10) ◽  
pp. 2229-2234
Author(s):  
Naeem Akhtar ◽  
Muhammad Waqas ◽  
Asma Naeem

Objectives: Chronic suppurative otitis media is the most common ear disease in Otolaryngology OPD and Head & Neck surgery in tertiary care hospitals worldwide. Due to its life threatening complications and management difficulties, attico-antral disease, a type of CSOM poses a huge challenge to otolaryngologists. Study Design: Descriptive study. Setting: Department of Otolaryngology and Head & Neck Surgery Allied Hospital (FMU) Faisalabad. Period: From January 2016 to December 2018. Material & Methods: Eighty five patients with CSOM of attico-antral type were included. Results: Forty six patients (54.1%) were male and thirty nine patients (45.9%) were female, aged 07 to 58 years with an average age of 23.7 years. 42 patients (49.4%) had a right ear disease and 43 patients (50.6%) had a left ear disease. Granulation tissue was observed in 50 patients (58.8%), cholesteatoma in 27 patients (31.7%) and both granulation tissue and cholesteatoma in 08 patients (09.5%). The main pathology was observed to involve the attic area only of 04 patients (04.7%), attic and middle ear of 44 patients (51.7%), attic and antrum of 16 patients (18.9%) and attic, middle ear, antrum and other mastoid air cells in 21 cases (24.7%). The malleus handle was found eroded in 10 patients (11.8%), head & handle in only 02 patients (02.4%). In 23 patients (27%) long process of incus was damaged while incus was completely eroded in 03 patients (03.5%). The suprastructure of stapes was found eroded in 03 patients (03.5%). Conclusion: Granulation tissue is the most common primary lesion along with cholesteatoma associated with attico-antral type of CSOM. Due to this pathology, the incus is the most frequently eroded small bone of the middle ear. In addition the management of granulation tissue and cholesteatoma poses a huge challenge to the otolaryngologists. Therefore, the general practitioners are needed to be educated for early referral to otolaryngologist for early and rapid management to prevent complications due to attico-antral type of CSOM.


1976 ◽  
Vol 85 (2_suppl) ◽  
pp. 63-65 ◽  
Author(s):  
Michael M. Paparella

Detailed morphological and physiological studies are necessary as a basis for understanding normal, near normal and abnormal conditions of the middle ear cleft. Animal and human studies are essential. Animal studies provide a means of controlling and isolating variables. Herein we describe methods of producing acute and chronic middle ear effusions in animals. An animal model has also been developed for purulent otitis media. Corollary comprehensive studies are underway in humans. A multidisciplinary effort including pathology, microbiology, immunology, histochemistry, etc., yields interesting information which helps explain the pathogenesis of these common clinical problems.


2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
Jizhen Lin ◽  
Per Caye-Thomasen ◽  
Tetsuya Tono ◽  
Quan-An Zhang ◽  
Yoshihisa Nakamura ◽  
...  

Otitis media (OM) with mucoid effusion, characterized by mucous cell metaplasia/hyperplasia in the middle ear cleft and thick fluid accumulation in the middle ear cavity, is a subtype of OM which frequently leads to chronic OM in young children. Multiple factors are involved in the developmental process of OM with mucoid effusion, especially disorders of mucin production resulting from middle ear bacterial infection and Eustachian tube dysfunction. In this review, we will focus on several aspects of this disorder by analyzing the cellular and molecular events such as mucin production and mucous cell differentiation in the middle ear mucosa with OM. In addition, infectious agents, mucin production triggers, and relevant signaling pathways will be discussed.


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