scholarly journals Imperial and Local: Audience and Identity in the Idrimi Inscription

2021 ◽  
Vol 9 (2) ◽  
pp. 28-46
Author(s):  
Jacob Lauinger
Keyword(s):  
Intended Audience ◽  
Local Populations ◽  
Local Expression

This article studies the Idrimi inscription from ancient Alalah, modern Tell Atchana, in order to explore how and to what effect manifestations of empire may have been socially consequential to local populations ruled by Mittani. Specifically, the article argues that Idrimi is presented as a Mittani hero, but the story of his life is told in a Northwest Semitic-Akkadian code; an imperial vision receives a local expression. From this conclusion, the article ends by trying to infer something about the inscription’s intended audience.

Thrombin Augments Vascular Cell-dependent Migration of Human Mast Cells: Role of MGF

1997 ◽  
Vol 77 (03) ◽  
pp. 577-584 ◽  
Author(s):  
Mehrdad Baghestanian ◽  
Roland Hofbauer ◽  
Hans G Kress ◽  
Johann Wojta ◽  
Astrid Fabry ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Mast Cells ◽  
Umbilical Vein ◽  
Vascular Cells ◽  
Migratory Response ◽  
Thrombin Activation ◽  
Umbilical Vein Endothelial Cells ◽  
Primary Tissue ◽  
Local Expression

SummaryRecent data suggest that auricular thrombosis is associated with accumulation of mast cells (MC) in the upper endocardium (where usually no MC reside) and local expression of MGF (mast cell growth factor) (25). In this study, the role of vascular cells, thrombin-activation and MGF, in MC-migration was analyzed. For this purpose, cultured human auricular endocardial cells (HAUEC), umbilical vein endothelial cells (HUVEC) and uterine-(HUTMEC) and skin-derived (HSMEC) microvascular endothelial cells were exposed to thrombin or control medium, and the migration of primary tissue MC (lung, n = 6) and HMC-1 cells (human MC-line) against vascular cells (supernatants) measured. Supernatants (24 h) of unstimulated vascular cells (monolayers of endocardium or endothelium) as well as recombinant (rh) MGF induced a significant migratory response in HMC-1 (control: 3025 ± 344 cells [100 ± 11.4%] vs. MGF, 100 ng/ml: 8806 ± 1019 [291 ± 34%] vs. HAUEC: 9703 ± 1506 [320.8 ± 49.8%] vs. HUTMEC: 8950 ± 1857 [295.9 ± 61.4%] vs. HSMEC: 9965 ± 2018 [329.4 ± 66.7%] vs. HUVEC: 9487 ± 1402 [313.6 ± 46.4%], p <0.05) as well as in primary lung MC. Thrombin-activation (5 U/ml, 12 h) of vascular cells led to an augmentation of the directed migration of MC as well as to a hirudin-sensitive increase in MGF synthesis and release. Moreover, a blocking anti-MGF antibody was found to inhibit MC-migration induced by unstimulated or thrombin-activated vascular cells. Together, these data show that endocardial and other vascular cells can induce migration of human MC. This MC-chemotactic signal of the vasculature is associated with expression and release of MGF, augmentable by thrombin, and may play a role in the pathophysiology of (auricular) thrombosis.

Cultivating Ice over Time: On the Idea of Timeless Knowledge and Places in the Himalayas

1969 ◽  
Vol 58 (2) ◽  
pp. 193-210 ◽  
Author(s):  
Karine Gagné
Keyword(s):  
Climate Change ◽  
Sense Of Community ◽  
Local Knowledge ◽  
Local Communities ◽  
International Organisations ◽  
Change Over Time ◽  
Local Populations ◽  
Close Study ◽  
Indian Himalayas ◽  
Over Time

Assumptions that local communities have an endogenous capacity to adapt to climate change stemming from time-tested knowledge and an inherent sense of community that prompts mobilisation are becoming increasingly common in material produced by international organisations. This discourse, which relies on ahistorical and apolitical conceptions of localities and populations, is based on ideas of timeless knowledge and places. Analysing the water-place nexus in Ladakh, in the Indian Himalayas, through a close study of glacier practices as they change over time, the article argues that local knowledge is subject to change and must be analysed in light of changing conceptions and experiences of place by the state and by local populations alike.

An Early Jesuit Encounter with the Qur’an

2017 ◽  
Vol 34 (1) ◽  
pp. 1-22
Author(s):  
Paul Shore
Keyword(s):  
Early Modern ◽  
Early Modern Period ◽  
European Language ◽  
Intended Audience ◽  
Modern Period ◽  
History Of ◽  
Western European

The manuscipt Animadversiones, Notae ac Disputationes in Pestilentem Alcoranum is an almost entirely unknown translation of the Qur'an into baroque Latin completed by the Jesuit priest Ignazio Lomellini in 1622, of which only one copy exists. It is accompanied by extensive commentaries and includes a complete text of the Qur’an in Arabic and numerous marginalia. It is, therefore, one of the earliest complete translations of the Qur’an into a western European language and a crucial document of the encounter between western Christianity and Islam in the early modern period. This essay examines Lomellini’s understanding of Arabic and, specifically, of the cultural and religious underpinnings of Qur’anic Arabic. Special attention is given to his lexical choices. This essay also deals with the document’s intended audience, the resources upon which he drew (including the library of his patron, Cardinal Alessandro Orsini), and the manuscript’s relationship to the Jesuits’ broader literary and missionary efforts. Finally, it asks why scholars, particularly those who study the history of the Jesuits, have ignored this manuscript and its author.

Local Expression of C-Type Natriuretic Peptide Markedly Suppresses Neointimal Formation in Rat Injured Arteries Through an Autocrine/Paracrine Loop

Circulation ◽  
1997 ◽  
Vol 96 (7) ◽  
pp. 2272-2279 ◽  
Author(s):  
Hikaru Ueno ◽  
Akihiro Haruno ◽  
Nobuhiro Morisaki ◽  
Mayumi Furuya ◽  
Kenji Kangawa ◽  
...  
Keyword(s):  
Natriuretic Peptide ◽  
Neointimal Formation ◽  
Local Expression

Comedy and the Athenian Ideal

2018 ◽  
Author(s):  
David Konstan
Keyword(s):  
American Democracy ◽  
Intended Audience ◽  
The World ◽  
Hollywood Movies ◽  
Hellenistic World ◽  
City State ◽  
The City ◽  
New Comedy ◽  
A Performance

New Comedy was a Panhellenic phenomenon. It may be that a performance in Athens was still the acme of a comic playwright’s career, but Athens was no longer the exclusive venue of the genre. Yet Athens, or an idealized version of Athens, remained the setting or backdrop for New Comedy, whatever its provenance or intended audience. New Comedy was thus an important vehicle for the dissemination of the Athenian polis model throughout the Hellenistic world, and it was a factor in what has been termed ‘the great convergence’. The role of New Comedy in projecting an idealized image of the city-state may be compared to that of Hollywood movies in conveying a similarly romanticized, but not altogether false, conception of American democracy to populations around the world.

Introduction

2017 ◽  
Author(s):  
Clare Chambers
Keyword(s):  
Ideal Theory ◽  
Free State ◽  
Regulatory Structure ◽  
Intended Audience ◽  
Political Commitments

The introduction sets out the arguments of Against Marriage: An Egalitarian Defence of the Marriage-Free State. It starts with the question of the intended audience for the book, discussing the implications for those with both personal and political commitments. It outlines the negative thesis against marriage offered in Part One, and the positive thesis in favour of an alternative regulatory structure in Part Two. It summarizes the contents of each chapter. It also includes a discussion of the book’s location within ideal and non-ideal theory.

Introduction

2018 ◽  
Author(s):  
Christine Cheng
Keyword(s):  
Theoretical Framework ◽  
Political Authority ◽  
The State ◽  
Dual Nature ◽  
For Profit ◽  
Business Interests ◽  
Local Populations ◽  
Post Conflict ◽  
Over Time ◽  
Commercial Environment

This chapter introduces the concept of extralegal groups and a theoretical framework for analyzing them—how they emerge, develop, and become entrenched over time. It explores their dual nature as threats to the state and as local statebuilders. Formally, an extralegal group is defined as a set of individuals with a proven capacity for violence who work outside the law for profit and provide basic governance functions to sustain its business interests. This framing shows how political authority can develop as a by-product of the commercial environment, even where the state has little or no presence. In post-conflict societies, the predatory nature and historical abuses of citizens conducted in the name of the state means that government is not always more trusted or better able to look after the interests of local populations than an extralegal group. Ultimately, extralegal groups blur the lines between the formal and informal; the licit and illicit.

Aspects of the Relationships between the Community of Sheikh Abd al-Qurna and Ancient Egyptian Monuments

2020 ◽  
pp. 507-522
Author(s):  
Andrew Bednarski ◽  
Gemma Tully
Keyword(s):  
Social Action ◽  
Single Case ◽  
Local Population ◽  
Social Awareness ◽  
Single Case Study ◽  
Local Populations ◽  
Ancient Egyptian ◽  
Complex Relationships

Epigraphers and archaeologists working in Egypt must navigate a host of complex relationships both on and off site. This chapter explores the multifaceted nature of local Egyptian peoples’ relationships with nearby monuments through the lens of a single case study: the site of Sheikh Abd al-Qurna and its local population, the Qurnawi. Egyptologists have not traditionally sought to incorporate formally the stories and histories of local populations in their studies of pharaonic sites. An increasing blend of social awareness and the desire for social action on the part of both foreign professionals and local activists, however, is pushing Egyptologists to re-evaluate their practices, which, in turn, is moving the discipline in new and positive directions.

scholarly journals POPULATION GENETICS OF ALLOZYME VARIATION IN NEUROSPORA INTERMEDIA

Genetics ◽  
1975 ◽  
Vol 80 (4) ◽  
pp. 785-805
Author(s):  
P T Spieth
Keyword(s):  
Genetic Variation ◽  
Vegetative Reproduction ◽  
Vascular Plant ◽  
Natural Populations ◽  
Allozyme Variation ◽  
Regular Feature ◽  
Local Populations ◽  
Neurospora Intermedia ◽  
Pattern Of Variation ◽  
High Level

ABSTRACT Electrophoretically detectable variation in the fungus Neurospora intermedia has been surveyed among isolates from natural populations in Malaya, Papua, Australia and Florida. The principal result is a pattern of genetic variation within and between populations that is qualitatively no different than the well documented patterns for Drosophila and humans. In particular, there is a high level of genetic variation, the majority of which occurs at the level of local populations. Evidence is presented which argues that N. intermedia has a population structure analogous to that of an annual vascular plant with a high level of vegetative reproduction. Sexual reproduction appears to be a regular feature in the biology of the species. Substantial heterokaryon function seems unlikely in natural populations of N. intermedia. Theoretical considerations concerning the mechanisms underlying the observed pattern of variation most likely should be consistent with haploid selection theory. The implications of this constraint upon the theory are discussed in detail, leading to the presentation of a model based upon the concept of environmental heterogeneity. The essence of the model, which is equally applicable to haploid and diploid situations, is a shifting distribution of multiple adaptive niches among local populations such that a given population has a small net selective pressure in favor of one allele or another, depending upon its particular distribution of niches. Gene flow among neighboring populations with differing net selective pressures is postulated as the principal factor underlying intrapopulational allozyme variation.

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