Rosa Gallica aggregatoris Lugdunēsis domini Symphoriani Chāperij omnibus sanitatē affectātibus vtilis & necessaria: Quę in se cōntinet pręcepta, auctoritates, atq, sentēntias memoratu dignas, ex Hippocratis, Galeni, Erasistrati, Asclepiadis, Diascoridis, Rasis, Haliabatis, Isaac, Auicēnæ, multorūq, aliorū clarorum virorum libris in vnum collectas: quæ ad medicam artem rectāq, viuendi formā plurimū conducūt, vna cū sua pretiosa Margarita: de Medici atq, ęgri officio.

Plants from the Rosacea family are rich in natural molecules with beneficial biological properties, and they are widely appreciated and used in the food industry, perfumery, and cosmetics. In this review, we are considering Rosa damascena Mill., Rosa alba L., Rosa centifolia L., and Rosa gallica L. as raw materials important for producing commercial products, analyzing and comparing the main biological activities of their essential oils, hydrolates, and extracts. A literature search was performed to find materials describing (i) botanical characteristics; (ii) the phytochemical profile; and (iii) biological properties of the essential oil sand extracts of these so called “old roses” that are cultivated in Bulgaria, Turkey, India, and the Middle East. The information used is from databases PubMed, Science Direct, and Google Scholar. Roses have beneficial healing properties due to their richness of beneficial components, the secondary metabolites as flavonoids (e.g., flavones, flavonols, anthocyanins), fragrant components (essential oils, e.g., monoterpenes, sesquiterpenes), and hydrolysable and condensed tannins. Rose essential oils and extracts with their therapeutic properties—as respiratory antiseptics, anti-inflammatories, mucolytics, expectorants, decongestants, and antioxidants—are able to act as symptomatic prophylactics and drugs, and in this way alleviate dramatic sufferings during severe diseases.

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Rose (Rosa gallica) Petal Extract Suppress Proliferation, Migration, and Invasion of Human Lung Adenocarcinoma A549 Cells through via the EGFR Signaling Pathway

Molecules ◽

10.3390/molecules25215119 ◽

2020 ◽

Vol 25 (21) ◽

pp. 5119

Author(s):

Won-Chul Lim ◽

Hyo-Kyung Choi ◽

Kyung-Tack Kim ◽

Tae-Gyu Lim

Keyword(s):

Lung Cancer ◽

Cell Proliferation ◽

Matrix Metalloproteinase ◽

Cancer Cells ◽

Cancer Cell ◽

A549 Cells ◽

Lung Cancer Cells ◽

Migration And Invasion ◽

Egfr Signaling Pathway ◽

Rosa Gallica

We sought to investigate the effect of rose petal extract (RPE) on the proliferation, migration, and invasion of cancer cells. RPE significantly inhibited the growth of lung and colorectal cancer cell lines, with rapid suppression of A549 lung cancer cells at low concentrations. These effects occurred concomitantly with downregulation of the cell proliferation mediators PCNA, cyclin D1, and c-myc. In addition, RPE suppressed the migration and invasion of A549 cells by inhibiting the expression and activity of matrix metalloproteinase-2 and matrix metalloproteinase-9 (MMP-2 and -9). We hypothesize that the suppressive activity of RPE against lung cancer cell proliferation and early metastasis occurs via the EGFR-MAPK and mTOR-Akt signaling pathways. These early results highlight the significant potency of RPE, particularly for lung cancer cells, and warrant further investigation.

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The Propagation of Rosa gallica ‘Tuscany Superb’ by Root Cuttings with the Use of IBA and Biostimulants

Notulae Botanicae Horti Agrobotanici Cluj-Napoca ◽

10.15835/nbha47311436 ◽

2019 ◽

Vol 47 (3) ◽

Author(s):

Marta Joanna MONDER ◽

Konrad WOLIŃSKI ◽

Maciej NIEDZIELSKI

Keyword(s):

Cross Sections ◽

Growth Parameters ◽

Digital Object Identifier ◽

Digital Object ◽

Rooted Cuttings ◽

Shoot Buds ◽

Alternative Method ◽

Rosa Gallica ◽

Cambium Zone ◽

Reducing Carbohydrates

The research was aimed at studying the possibility of an alternative method of propagation the difficult-to-root Rosa gallica ‘Tuscany Superb’. The root cuttings of three thickness were rooted using IBA preparations (Chryzotop green, Rhizopon AA 020XX) and biostimulants (Tytanit, Root JuiceTM). The shoots disappeared before the growth of the roots. At the first days of growth, the both shoots and roots elongated upright without polarity. The primordia of the first type of root/shoot buds were situated in cambium zone as the subtending traces of near the rays visible on the cross sections. Moreover, the second types of buds were located in pericycle tissues. The swellings suggested inherence buds were disappearing before rooting. The content of reducing and non-reducing carbohydrates was lower at the time of harvesting the rooted cuttings than before rooting. The thickness of the root cuttings had a significant importance for growth parameters and content of carbohydrates in rooted cuttings. The most useful root cuttings, those achieving the highest mean rooting percentage are thick (76.8%) and medium (67.9%) size. Preparations or biostimulants had a differential influence on rooting process and none of them unequivocally guaranteed an improvement in the rooting percentage of cuttings, parameters of growth or content of carbohydrates. The Rhizopon AA 020XX (90.0%) in thick and Chryzotop green (87.5%) in medium cuttings increased the rooting percentage significantly. Root JuiceTM (0.1%, 0.2%) and Tytanit (0.04%) were also enough positive activity in medium cuttings and can replace IBA preparations. ********* In press - Online First. Article has been peer reviewed, accepted for publication and published online without pagination. It will receive pagination when the issue will be ready for publishing as a complete number (Volume 47, Issue 3, 2019). The article is searchable and citable by Digital Object Identifier (DOI). DOI link will become active after the article will be included in the complete issue. *********

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