Interaction of D-Amphetamine and Food Deprivation on Fixed Ratio Behavior of Pigeons

1967 ◽  
Vol 20 (2) ◽  
pp. 355-358 ◽  
Author(s):  
Richard F. Meginniss

Four groups of 6 pigeons, maintained at 100, 90, 80, and 70% of their ad libitum feeding weight, showed directly proportional weight-dependent depressant effects on fixed ratio key pecking following d-amphetamine treatment.

2001 ◽  
Vol 280 (3) ◽  
pp. R669-R677 ◽  
Author(s):  
Elizabeth M. Starbuck ◽  
Douglas A. Fitts

A lesion of the subfornical organ (SFO) may disrupt drinking after a meal of dry chow as it does drinking after intragastric administration of hypertonic saline. Food and water intakes of SFO-lesioned (SFOX) and sham-lesioned rats were measured during 90-min tests following various lengths of food deprivation. During the tests, all rats began eating before they began drinking. After 20–24 h of food deprivation, latency to begin drinking after eating had started was longer for SFOX than for sham-lesioned rats. Plasma osmolality was elevated by 2–3% in both lesion groups at 12 min, the latency for sham-lesioned rats to drink, but SFOX rats nevertheless continued eating and delayed drinking. Eating after shorter 4-h food deprivations and ad libitum feeding produced more variable drinking latencies and less consistent effects of SFO lesion. During 24 h of water deprivation, SFO lesion had no effect on the suppression of food intake and did not affect food or water intakes during the first 2 h of subsequent rehydration. These findings indicate that the SFO is involved in initiating water intake during eating and in determining drinking patterns and the amount of water ingested during a meal.


Behaviour ◽  
1966 ◽  
Vol 26 (3-4) ◽  
pp. 351-356 ◽  
Author(s):  
Edward T. Uyeno ◽  
R. Alan Graham

AbstractMale Wistar rats were deprived of food for 3 days and then forced to swim continuously to a criterion of exhaustion. Controls swam after ad libitum feeding. In the first experiment a load equal to 11% of the rat's body weight was attached to the dorsal skin near the tail during the swim. In a second study, two matched groups, treated identically as those in the first study swam without a load in water treated with a wetting agent, "Aerosol O.T." In a third experiment, controls as well as experimentals were deprived of food for three days. The control group, however, was fed for 30 minutes, immediately before the swim. A fourth experiment was conducted in a similar manner as the third, except both groups were deprived 6 hours. In each of the experiments the deprived groups swam significantly longer than the fed groups.


1983 ◽  
Vol 245 (3) ◽  
pp. R339-R344 ◽  
Author(s):  
K. I. Honma ◽  
S. Honma ◽  
T. Hiroshige

The effects of food on plasma corticosterone levels were examined in rats under restricted daily feeding or prolonged food deprivation. High hormone levels before feeding were observed when the daily meal was restricted to 2 h at a fixed time of day, but it was not detected when food availability was extended to 6 h. The amount of food intake under the latter condition was comparable to that in 24 h of ad libitum feeding. After the termination of restricted feeding, the prefeeding hormone peak was maintained in rats fasted subsequently but disappeared when rats were returned to ad libitum feeding. Food deprivation for 10 days increased plasma corticosterone levels in the light period, resulting in abolition of the circadian rhythm. A subsequent meal decreased the hormone level such that the 24-h mean hormone level after food ingestion was inversely related to the amount of food intake. When rats were allowed to feed for 6 h after prolonged food deprivation, the prefeeding hormone peak observed at the second meal disappeared at the fourth meal. The amount of food consumption in these rats increased and reached a level comparable to that with ad libitum feeding at the third meal. It is concluded that the amount of food intake is critical for the development and maintenance of the prefeeding hormone peak under restricted feeding; prolonged fasting.


1996 ◽  
Vol 271 (2) ◽  
pp. E239-E245 ◽  
Author(s):  
T. Yoshihara ◽  
S. Honma ◽  
Y. Katsuno ◽  
K. Honma

Extracellular neuropeptide Y (NPY) in the vicinity of the paraventricular nucleus (PVN) as well as NPY concentrations in the PVN were measured in rats under ad libitum feeding and 2-day and 10-day food deprivation. Plasma corticosterone levels were not changed by 2-day food deprivation but were increased by subsequent refeeding. In contrast, the extracellular NPY levels were increased by 2-day food deprivation and were decreased rapidly by refeeding. The NPY concentrations were also increased and increased further by refeeding. On the other hand, plasma corticosterone levels were elevated by 10-day food deprivation and were decreased by subsequent refeeding. The extracellular NPY levels were also increased by food deprivation and decreased gradually after refeeding. However, the postprandial levels were still elevated when plasma corticosterone levels were returned to the basal levels. The NPY concentrations were also increased and increased further by refeeding. The amount of food intake after refeeding was positively correlated with the extracellular NPY levels. It is concluded that extracellular NPY levels in the PVN do not necessarily covariate with plasma corticosterone levels in rats under food deprivation.


1968 ◽  
Vol 22 (3_suppl) ◽  
pp. 1125-1128
Author(s):  
Lowell T. Crow

Daily patterns of drinking were observed in rats under ad libitum feeding conditions and with a 22-hr. food deprivation schedule. It was found that feeding restricted to a specific hour set the daily drinking pattern and allowed a control of daily water-regulatory cycles. The amount of water ingested was found to be greater under the 22-hr. food deprivation than with ad libitum feeding.


1994 ◽  
Vol 266 (4) ◽  
pp. E606-E611
Author(s):  
M. Mitome ◽  
S. Honma ◽  
T. Yoshihara ◽  
K. Honma

Extracellular norepinephrine (NE) in the vicinity of the paraventricular nucleus was continuously measured over 24 h by means of in vivo microdialysis in rats under restricted daily feeding and ad libitum feeding. A 24-h rhythm in plasma corticosterone was monitored in separate rats under identical conditions. Under ad libitum feeding, the paraventricular NE showed a 24-h rhythm with lower levels in the light period and higher levels in the dark period. The temporal pattern was not affected by food deprivation for 3 days. The circadian peak of paraventricular NE lagged slightly behind that of plasma corticosterone under ad libitum feeding. On the other hand, when rats were fed for 2 h at a fixed time of day for 3 wk, the NE rhythm was changed and showed a major peak just before daily meals. To examine the nature of the prefeeding NE peak, a 24-hour variation of paraventricular NE was measured in rats under food deprivation that had been subjected to restricted daily feeding for 3 wk and subsequently to ad libitum feeding for 7 days. The paraventricular NE was high around the time when meal had been supplied under restricted daily feeding and low in the dark period. Similar changes were observed in plasma corticosterone. The findings indicate that the prefeeding increase in the paraventricular NE release is regulated by a feeding-associated circadian rhythm manifest in rats under restricted daily feeding.


1982 ◽  
Vol 55 (2) ◽  
pp. 515-519 ◽  
Author(s):  
S. Kowalski ◽  
G. H. Parker ◽  
M. A. Persinger

Mice that had been given either tap water or 2 ppm lead in their drinking water and either severely food deprived (3 days before testing) or allowed food ad libitum demonstrated significant interactions of lead treatment by day by food condition and lead by block. Although not statistically significant, the food deprived-lead treated mice displayed more errors and longer latencies than the ad libitum-water controls. The food deprived-water controls and ad libitum-lead-treated mice displayed intermediate values. The importance of using multivariate statistical techniques that can evaluate dynamic repeated behavioral measurements is emphasized.


1994 ◽  
Vol 59 (2) ◽  
pp. 263-269 ◽  
Author(s):  
N. D. Cameron ◽  
M. K. Curran

AbstractResponses to divergent selection for lean growth rate with ad-libitum feeding (LGA), for lean food conversion (LFC) and for daily food intake (DFI) in Landrace pigs were studied. Selection was practised for four generations with a generation interval ofl year. A total of 2642 pigs were performance tested in the high, low and control lines, with an average of 37 boars and 39 gilts performance tested per selection line in each generation. The average within-line inbreeding coefficient at generation four was equal to 0·04. There was one control line for the DFI and LFC selection groups and another control line for the LGA selection group. Animals were performance tested in individual pens with mean starting and finishing weights of 30 kg and 85 kg respectively with ad-libitum feeding. The selection criteria had phenotypic s.d. of 32, 29 and 274 units, for LGA, LFC and DFI, respectively, and results are presented in phenotypic s.d.Cumulative selection differentials (CSD) were 5·1, 4·5 and 5·5 phenotypic s.d. for LGA, LFC and DFI, respectively. Direct responses to selection were 1·4,1·1 and 0·9 (s.e. 0·20) for LGA, LFC and DFI. In each of the three selection groups, the CSD and direct responses to selection were symmetric about the control lines. The correlated response in LFC (1·1, s.e. 0·19) with selection on LGA was equal to the direct response in LFC. In contrast, the direct response in LGA was greater than the correlated response (0·7, s.e. 0·18) with selection on LFC. There was a negative correlated response in DFI (-0·6, s.e. 0·18) with selection on LFC, but the response with selection on LGA was not significant (0·2, s.e. 0·16).Heritabilities for LGA, LFC and DFI ivere 0·25, 0·25 and 0·18 (s.e. 0·03), when estimated by residual maximum likelihood, with common environmental effects of 0·12 (s.e. 0·02). Genetic correlations for LFC with LGA and DFI were respectively positive (0·87, s.e. 0·02) and negative (-0·36, s.e. 0·09), while the genetic correlation between DFI and LGA was not statistically different from zero, 0·13 (s.e. 0·10). Selection on components of efficient lean growth has identified LGA as an effective selection objective for improving both LGA and LFC, without a reduction in DFI.


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