Special Considerations in Administering the Quick Test to Mentally Retarded and Central Nervous System-Impaired Subjects

1981 ◽  
Vol 49 (1) ◽  
pp. 308-310
Author(s):  
Bill D. Persinger
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Mentally Retarded ◽  
Self Perception ◽  
Quick Test ◽  
And Control

Eight special considerations are reported for use with the Quick Test (Ammons & Ammons, 1962) when testing mentally retarded or central nervous system-impaired subjects. Use of these techniques may result in a more accurate IQ. The techniques pertain to the manner of presenting stimuli, examiner's empathy, subject's self-perception, and control of guessing. The techniques are intended to supplement directions that appear in the Quick Test manual.

scholarly journals Differential and Common Signatures of miRNA Expression and Methylation in Childhood Central Nervous System Malignancies: An Experimental and Computational Approach

Cancers ◽  
2021 ◽  
Vol 13 (21) ◽  
pp. 5491
Author(s):  
George I. Lambrou ◽  
Myrto Poulou ◽  
Krinio Giannikou ◽  
Marios Themistocleous ◽  
Apostolos Zaravinos ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Central Nervous System ◽  
Nervous System ◽  
Mirna Expression ◽  
Tumor Staging ◽  
Gene Promoter ◽  
Tumor Type ◽  
Gene Methylation ◽  
Microarray Screening ◽  
And Control

Epigenetic modifications are considered of utmost significance for tumor ontogenesis and progression. Especially, it has been found that miRNA expression, as well as DNA methylation plays a significant role in central nervous system tumors during childhood. A total of 49 resected brain tumors from children were used for further analysis. DNA methylation was identified with methylation-specific MLPA and, in particular, for the tumor suppressor genes CASP8, RASSF1, MGMT, MSH6, GATA5, ATM1, TP53, and CADM1. miRNAs were identified with microarray screening, as well as selected samples, were tested for their mRNA expression levels. CASP8, RASSF1 were the most frequently methylated genes in all tumor samples. Simultaneous methylation of genes manifested significant results with respect to tumor staging, tumor type, and the differentiation of tumor and control samples. There was no significant dependence observed with the methylation of one gene promoter, rather with the simultaneous presence of all detected methylated genes’ promoters. miRNA expression was found to be correlated to gene methylation. Epigenetic regulation appears to be of major importance in tumor progression and pathophysiology, making it an imperative field of study.

scholarly journals The value of neurohumoral regulation in the outcome of multiple organ failure syndrome in sepsis

2020 ◽  
Vol 17 (5) ◽  
pp. 80-86
Author(s):  
M. A. Leontiev ◽  
A. B. Vodova ◽  
S. V. Kravchuk
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Multiple Organ Failure ◽  
Organ Failure ◽  
Multiple Organ ◽  
Neurohumoral Regulation ◽  
The Central Nervous System ◽  
Quantitative Changes ◽  
Mechanisms Of Development ◽  
And Control

The objective: to present information about potential mechanisms of development of sepsis-associated encephalopathy, and its potential role in sepsis outcome.Neurohumoral regulation is the most important system that integrates many functions of variable values to achieve the final result that is beneficial for the host. The central nervous system (CNS) is the switch and control mechanism responsible for the functioning of this system. The increasing number of studies indicating the relationship between the development of sepsis and occurrence of qualitative and quantitative changes in the central nervous system suggests that it is the degree of damage to neurohumoral regulation mechanisms at the very beginning of the disease can significantly determine the severity of the course and prognosis of the outcome of multiple organ failure syndrome in sepsis.

MATHEMATIC SIMULATION OF BIOELECTRIC HIP PROSTHESIS MOVEMENT

2017 ◽  
pp. 7-13
Author(s):  
Aleksey Anatolivich Kulik
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Hip Prosthesis ◽  
Control Device ◽  
Nerve Fibers ◽  
Primary Data ◽  
The Central Nervous System ◽  
Physical Abilities ◽  
Prosthesis Control ◽  
And Control

The purpose of the study was to develop a mathematical mechanism which could describe laws of changing electrical signals in nerve fibers in man’s lower extremities and hip prosthesis movement. The article presents a schematic diagram of the bioelectric hip prosthesis control system, main elements of which are an actuator, a control device, and a primary data unit. There are given actual mathematical models of prostheses movement and control signals of man’s central nervous system; on their base was designed the mathematical model controlling bioelectric hip prosthesis movement. A specific feature of the model offered is that the model has a function to characterize a signal transfer from the central nervous system to the actuator of prosthesis. The research results can be applied in the course of hardware and software implementation of bioelectrical prostheses, taking into account physical abilities of the users, creating specific algorithms, studying electric and dynamic characteristics of these devices.

Transport and Control of Manganese Ions in the Central Nervous System

1999 ◽  
Vol 80 (2) ◽  
pp. 96-98 ◽  
Author(s):  
H.Vasken Aposhian ◽  
Russell T. Ingersoll ◽  
Erwin B. Montgomery
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Manganese Ions ◽  
The Central Nervous System ◽  
And Control

Anthropomorphizing the CNS: Is it what or who you know?

1996 ◽  
Vol 19 (1) ◽  
pp. 90-91
Author(s):  
Michael G. Wade ◽  
Jinhua Guan
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Motor Control ◽  
Complex Systems ◽  
Motor Skill ◽  
Systems Perspective ◽  
System A ◽  
Target Article ◽  
And Control ◽  
Coordination And Control

AbstractThe target article pays insufficient attention to (1) the difficulties that arise when the term “normal” is used to describe motor skill behavior, and (2) the need to resist ascribing motor control to an intelligent central nervous system. A complex systems perspective is proposed with attractor states and periodicity identified as markers of atypical coordination and control.

Should stereotypic movement synergies in hemiparetic patients be considered adaptive?

1996 ◽  
Vol 19 (1) ◽  
pp. 79-80 ◽  
Author(s):  
Mindy F. Levin
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Motor Deficits ◽  
Impaired Ability ◽  
The Central Nervous System ◽  
And Control ◽  
Stereotypic Movement ◽  
The Continuum

AbstractThe motor deficits observed in patients following some lesions of the central nervous system may be viewed as falling at one extreme of the continuum of possible motor behaviours. They are usually associated with an impaired ability to select and control specific movements from the available repertoire. Such movements may not be viewed as abnormal. However, it is unlikely that the primary motor deficits can all be considered adaptive.

Maternal Hyperglycemia Leads to Gender-Dependent Deficits in Learning and Memory in Offspring

2003 ◽  
Vol 228 (2) ◽  
pp. 152-159 ◽  
Author(s):  
B.A. Kinney ◽  
M.B. Rabe ◽  
R.A. Jensen ◽  
R.W. Steger
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
System Development ◽  
Inhibitory Avoidance ◽  
Female Offspring ◽  
Nervous System Development ◽  
Diabetic Woman ◽  
Sprague Dawley ◽  
Increased Risk ◽  
And Control

Pregnancy in the diabetic woman has long been associated with an increased risk of congenital malformation in the offspring. However, little is known about the effects of maternal diabetes on development of the central nervous system. To begin to gain an understanding of this problem, diabetes was induced in adult female Sprague-Dawley rats by injection with streptozotocin. Only animals with serum glucose levels greater than 200 mg/dl were used. Diabetic and control females were bred, and all newborn pups were cross-fostered to nondiabetic mothers. At 60 days of age, pups were tested in an elevated plus-maze to assess differences in emotionality and anxiety. There were no significant differences between offspring of diabetic dams and controls on this measure. All pups were then housed individually, put on food restriction, and maintained at 85% of their ad libitum weight. They were then trained in a Lashley III maze, which assesses learning and retention capability. The female offspring of diabetic dams performed poorer than controls, a finding that was supported by inhibitory avoidance data from a separate group of animals. All animals were then trained in a radial-arm maze. Results failed to find differences between experimental and control animals. It was concluded that the diabetic intrauterine environment has gender-specific effects on central nervous system development.

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