The prevalence of dogs with lymphocyte proliferative responses to food allergens in canine allergic dermatitis

2013 ◽  
Vol 16 (4) ◽  
pp. 735-739 ◽  
Author(s):  
K. Kawano ◽  
K. Oumi ◽  
Y. Ashida ◽  
Y. Horiuchi ◽  
T. Mizuno

Abstract The aim of the present study was to examine the correlation between the results of lymphocyte proliferative test (LPT) specific to food allergens and allergic skin diseases in dogs. Investigations were performed in 138 dogs with allergic skin diseases diagnosed in a private animal hospital. Of the 138 animals, 97 cases had positive reactions in LPT specific to food allergens. Of these 97 dogs, 67 animals were diagnosed with canine atopic dermatitis (CAD), but 30 dogs did not have IgE antibodies to environmental allergens. As 14 dogs out of 30 animals showed a positive result, 12 dogs underwent elimination diet trial based on the test results and all of them showed improvement in the pruritus score. Therefore, we conclude that LPT is an effective diagnostic test for allergic skin disease. Results of the lymphocyte test are useful in the identification of food allergens for the elimination diet trial

2021 ◽  
Vol 9 (7) ◽  
pp. 1452-1456
Author(s):  
Manish Choudhari ◽  
Nikita Jamadari ◽  
Naresh Jain

Objective - To increase awareness of the psychosocial impact of Kushtha, Visarpa, Mukhadushika, Sheetpitta, Udarda and Kotha in Ayurveda and Acne vulgaris, Urticaria, Various types of fungal infections, Atopic dermatitis, Psoriasis etc. in modern point of view. Quality Of Evidence - A literature review was based on a MEDLINE search (1966 to 2000). Selected articles from the dermatologic and psychiatric literature, as well as other relevant medical journals, were reviewed and used as the basis for discussion of how skin disease affects patients’ lives and of appropriate management. Message - Dermatologic problems hurt patients’ quality of life. skin disease can produce stress, anxiety, anger, depression, low self-esteem, embarrassment, and other psychological, personal, professional and social life problems that affect patients’ lives in ways comparable to arthritis or other disabling illnesses, as well as showing a bidirectional relationship between skin disease and psychological distress. This review focuses on the effects of five common skin diseases seen by family physicians- Acne, Urticaria, Various types of fungal infections, Atopic dermatitis and Psoriasis. Conclusion - How skin disease affects psychosocial well-being is un- derappreciated. Increased understanding of the psychiatric comorbidity associated with skin disease and a biopsy- chosocial approach to management will ultimately improve patients’ lives. Keywords: Skin disease, Psychosocial Impact, Quality of life.


2005 ◽  
Vol 41 (2) ◽  
pp. 92-97 ◽  
Author(s):  
Rosanna Marsella

The introduction of calcineurin inhibitors represents a major addition to the armamentarium of drugs available to veterinary clinicians for the management of allergic skin diseases. Both cyclosporine and tacrolimus have been proven to be well tolerated and effective for the treatment of atopic dermatitis in dogs. Although broad spectrum in their mechanism of action, they lack the major adverse effects of glucocorticoids and provide an appealing alternative to traditional therapies. The purposes of this article are to review clinically relevant information regarding these agents and to provide tips for maximizing the benefit obtained from these therapies.


2012 ◽  
Vol 9 (2) ◽  
pp. 35-44
Author(s):  
D Sh Macharadze

Atopic dermatitis (AD) — a chronic inflammatory skin disease with a broad spectrum of clinical symptoms. It is diagnosed mainly clinically. Sensitization to inhalled and food allergens may play a role in the development of AD. Thus, it is important to determine the presence of sensitization for environmental control and allergen avoidance, pharmacotherapy, and immunotherapy.


2018 ◽  
Vol 25 (3) ◽  
pp. 24-27
Author(s):  
M. M. BEN ◽  
E. YU. YANCHEVSKAYA ◽  
O. A. MESNYANKINA

Aim. To improve the diagnosis of allergic skin diseases in childrenMaterials and methods. 135 children aged from 2 to 6 with atopic dermatitis were examined during exacerbation. They were on inpatient treatment in the skin and venereologic department of the Regional skin and venereologic dispensary and the Department of Allergology of the Regional children's clinical hospital. At the same time, 103 people (the main group) had uncomplicated course of the disease, 32 patients had complications of atopic dermatitis in the form of secondary infection. The control group consisted of 29 children aged 2 to 6. Neopterin in serum was determined by enzyme-linked immunosorbent analysis using test kits "Neopterin ELISA" (Germany). Statistical reliability of the obtained data was evaluated using The Student's test.Results. Atopic dermatitis in children, regardless of clinical manifestations, is accompanied by an increase in the content of neopterin in serum. The nature of the increase in the level of neopterin is determined by the duration of the disease, while its highest values are characteristic of the prolonged course of the process (over 4 years).Conclusion. The determination of neopterin in children with atopic dermatitis is a promising laboratory method for assessing the severity of dermatosis, monitoring and forecasting the further course of the process, as well as evaluating the effectiveness of therapeutic measures.


2016 ◽  
Vol 19 (6) ◽  
pp. 334-339
Author(s):  
Elena Yu. Yanchevskaya ◽  
O. A Bashkina ◽  
Ben Mbarek Makrem

The article is devoted to the analysis of methods to assess the degree of atopic dermatitis (AD) severity, of their clinical manifestations and laboratory diagnosis. Treatment and prognosis of atopic dermatitis depends on the assessment of disease severity. The severity of the disease is the main factor for a doctor in the therapy of a child with AD. There are many scientific studies devoted to the objective classification of diseases and the development of the most effective methods of severity assessment. It is not always possible to quickly determine objectively measurable parameters ofpathologic skin process. Because of that assessment methods of skin diseases are often approximate and subjective. The new pathogenetic data of atopic dermatitis and the main types of defects are described. Dermatology indexes of atopic dermatitis severity were considered. The new biochemical methods to assess the degree of atopic dermatitis severity in children by measuring indicators of spontaneous adhesion of neutrophils were analyzed. Immunological method, in which serum of children with atopic dermatitis is determined by the level of total IgE and IgE antibodies to allergens, with using ImmunoCAP 100 and level IgG- and IgE-antibodies against tissue antigens by ELISA, were analyzed. The indicators of oxidative status were examined. The concentration of circulating biological peroxides (PPI) and nukliozida 8-OHdG (8-hydroxy-2’-deoxyguanosine) differed significantly in mild, moderate and severe AD. Bacteriological methods, based on an integrated assessment of microbiological parameters, characterizing the nonspecific resistance of skin and mucous membranes in the assessment of severity and prognosis of atopic dermatitis in children, were performed.


2019 ◽  
Vol 3 (3) ◽  
pp. 435-442
Author(s):  
Feriantano Sundang Pranata ◽  
Jufriadif Na’am ◽  
Sumijan

Fungal skin disease is a type of disease that is often suffered people in the tropics. Phenomena in the community often assume that this disease will heal by itself. However, if left the effects of fungal skin disease can worsen the sufferer condition. The importance of early detection and treatment is very necessary, but this requires patients go to hospital or doctor so that patients spend a lot of time and money. For this reason, was build an android expert system with speech to early diagnose fungal skin diseases. From this initial diagnosis will save time and money and provide alternative prevention for sufferers. The method used in this study is the Certainty Factor of 20 patients. The accuracy of the test results to the system compared to the results of the doctor's diagnosis is 95%. So that, this expert system can be an early alternative in diagnose fungal skin diseases in humans.


Author(s):  
Dr. Subhash B. Jamdhade ◽  
Namrata kende ◽  
Dr. S. K. Jaiswal ◽  
Dr. Pradnya. S. Jamdhade

ABSTRACT In ayurveda all skin diseases describes under the heading of kushta .  "Kushnatee iti kushtham."       ( Ma.Ni/kushta/Tika 1) The disease that destroyes the affected part of skin . Both charak samhita and sushrut samhita  classify skin disease into 2 categories . 1) Mahakushtha (major) 2) Kshudrakushtha (minor)                                               ....... Ch.ni 5/4 Ayurvedically, Eczema is considered to be a type of kushtha. i. e.type of kushdrakushtha which is disease of the skin .It is also known as a type of twak roga .which also signifies that it is a skin disease that twak translates to skin and rog translates to pain . Vicharchika is characterised by the following symptoms ati kandu ,bahu strav ,rukshta ,shyavata ,pidika,raji. As described in terms od nidan ,purvarupa,samprapti and chikitsa vicharchika can most certainly be corelated with the modern interpretation of eczema or atopic dermatitis .Eczema or atopic dermatitis is chronic inflammatory skin condition. Atopic dermatitis is characterised by  cracked or scaly skin discolored patches,erythma(red skin),papules, exudate(oozing) and intence pruritus (itching ).


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