scholarly journals Carbon ceramic electrode incorporated with zeolite ZSM-5 for determination of Piroxicam

2010 ◽  
Vol 8 (1) ◽  
pp. 155-162 ◽  
Author(s):  
Karim Asadpour-Zeynali ◽  
Mir Majidi ◽  
Mitra Zarifi
Keyword(s):  
Modified Electrode ◽  
Pharmaceutical Formulations ◽  
Differential Pulse ◽  
Solution Ph ◽  
Carbon Ceramic Electrode ◽  
Experimental Parameters ◽  
Voltammetric Behavior ◽  
Carbon Ceramic ◽  
Optimized Conditions

AbstractA new chemically modified electrode is constructed based on carbon ceramic electrode incorporated with zeolite ZSM-5. Voltammetric behavior of piroxicam at the carbon ceramic zeolite modified electrode (CCZME) was investigated. The modified electrode exhibited catalytic activity toward the electrooxidation of piroxicam. Experimental parameters such as solution pH, scan rate, concentration of piroxicam and zeolite amount were studied. It has been shown that using the CCZME, piroxicam can be determined by differential pulse voltammetry (DPV) and hydrodynamic amperometry (HA). Under the optimized conditions the calibration plots are linear in the concentration ranges of 0.20–25.00 and 0.20–50.10 μM with limit of detections of 0.65 and 0.29 μM for DPV and HA, respectively. The modified electrode with DPV and HA methods was successfully applied for analysis of piroxicam in pharmaceutical formulations. The results were favorably compared to those obtained by the spiked method. The results of the analysis suggest that the proposed method has promise for the routine determination of piroxicam in the products examined.

scholarly journals Carbon nanotube-ionic liquid nanocomposite modified carbon-ceramic electrode for determination of dopamine in real samples

2013 ◽  
Vol 11 (7) ◽  
pp. 1172-1186 ◽  
Author(s):  
Mir Majidi ◽  
Reza Baj ◽  
Abdolhossein Naseri
Keyword(s):  
Ionic Liquid ◽  
Carbon Nanotube ◽  
Modified Electrode ◽  
Electrochemical Impedance ◽  
Differential Pulse ◽  
Selective Determination ◽  
Carbon Ceramic Electrode ◽  
Electro Oxidation ◽  
Carbon Ceramic

AbstractRoom temperature 1-butyl-3-methylimidazolium tetraflouroborate ([BMIM][BF4]) ionic liquid was employed for dispersion of multi walled carbon nanotubes (MWCNTs) and the formation of nanocomposite on the surface of a carbon-ceramic electrode. The surface of the modified electrode was characterized using scanning electron microscopy and electrochemical impedance spectroscopy. The modified electrode exhibited excellent electrochemical activity to oxidation of dopamine (DA); whereas electro oxidation of ascorbic acid (AA) was not seen and electro oxidation of uric acid (UA) appeared at a more positive potential than DA. The multi walled carbon nanotube-ionic liquid nanocomposite modified carbon-ceramic electrode was used for the selective determination of DA in the presence of high levels of AA and UA using differential pulse voltammetry. The calibration curve for DA was linear in the range of 3.00 to 130 µM with the detection limit (S/N=3) of 0.87 µM. The present electrode was successfully applied to the determination of DA in some commercial pharmaceutical samples and human blood serum.

Electrochemical Behavior and Voltammetric Determination of Losartan Using Carbon Ceramic Electrode Modified with Room Temperature Ionic Liquid

2020 ◽  
Vol 18 (4) ◽  
pp. 322-327
Author(s):  
Mahzad Firouzi ◽  
Masoud Giahi ◽  
Mostafa Najafi ◽  
Seyed Saied Homami ◽  
Seyed Husain Hashemi Mousavi
Keyword(s):  
Ionic Liquid ◽  
Room Temperature ◽  
Dynamic Range ◽  
Electrochemical Impedance ◽  
Linear Sweep Voltammetry ◽  
Pharmaceutical Formulations ◽  
Room Temperature Ionic Liquid ◽  
Carbon Ceramic Electrode ◽  
Carbon Ceramic

Herein, an electrochemical sensor has been proposed for the determination of losartan (LOS) in pharmaceutical formulations. A room temperature ionic liquid, 1-butyl-3-methylimidazolium hexafluorophosphate (BMIM.PF6) was applied to fabricate a modified carbon ceramic electrode (IL-CCE). The electrochemical studies were performed by the cyclic and linear sweep voltammetry (CV and LSV), chronoamperometry and electrochemical impedance spectroscopy (EIS) techniques. The anodic peak currents were increased with the LOS concentration and indicated a linear dynamic range from 20 to 200 μM and a detection limit of 11.7 μM (S/N = 3) under the optimized conditions. Satisfactory results were obtained by analysis of LOS in pharmaceutical tablets.

scholarly journals A novel dopamine electrochemical sensor based on La3+/ZnO nanoflower modified graphite screen printed electrode

2019 ◽  
Vol 9 (3) ◽  
pp. 187-195 ◽  
Author(s):  
Somayeh Tajik ◽  
Hadi Beitollahi ◽  
Mohammad Reza Aflatoonian
Keyword(s):  
Modified Electrode ◽  
Phosphate Buffer Solution ◽  
High Sensitivity ◽  
Differential Pulse ◽  
Electrochemical Determination ◽  
Screen Printed Electrode ◽  
Buffer Solution ◽  
Optimized Conditions ◽  
Screen Printed

Flower-like La3+/ZnO nanocomposite was facile synthesized. A simple and ultrasensitive sensor based on graphite screen printed electrode (SPE) modified by La3+/ZnO nanoflower was developed for the electrochemical determination of dopamine. The electrochemical behavior of dopamine was studied in 0.1 M phosphate buffer solution (PBS) using cyclic voltammetry (CV), chronoamperometry (CA) and differential pulse voltammetry (DPV). Compared with the unmodified graphite screen printed electrode, the modified electrode facilitates the electron transfer of dopamine, since it notably increases the oxidation peak current of dopamine. Also, according to CV results the maximum oxidation of dopamine on La3+/ZnO/SPE occurs at 150 mV which is about 140 mV more negative compared with unmodified SPE. Under optimized conditions, the modified electrode exhibited a linear response over the concentration range from 0.15 to 300.0 μM, with a detection limit of 0.08 μM (S/N = 3). The proposed sensor exhibited a high sensitivity, good stability and was successfully applied for dopamine determination in dopamine ampoule, with high recovery.

scholarly journals Electrochemical Polymerised Graphene Paste Electrode and Application to Catechol Sensing

2019 ◽  
Vol 13 (1) ◽  
pp. 81-87 ◽  
Author(s):  
Jamballi G. Manjunatha
Keyword(s):  
Modified Electrode ◽  
Limit Of Detection ◽  
Phosphate Buffer Solution ◽  
Sample Pretreatment ◽  
Differential Pulse ◽  
Buffer Solution ◽  
Solution Ph ◽  
Graphene Paste Electrode ◽  
Paste Electrode

Objective: To build up an advantageous strategy for sensitive determination of catechol (CC), a poly (proline) modified graphene paste electrode (PPMGPE) was fabricated and used as a voltammetric sensor for the determination of CC. Methods: The performance of the modified electrode was studied using cyclic voltammetric (CV) and differential pulse voltammetric method (DPV). The modified electrode was characterized by CV and DPV. The surface of the modified electrode was examined by FESEM. The electrochemical behavior of CC in phosphate buffer solution (pH 7.5) was inspected using bare graphene paste electrode (BGPE) and PPMGPE. Results & Conclusion: The PPMGPE shows a lower limit of detection, calculated to be 8.7×10–7mol L−1 (S/N=3). This modified electrode was applied successfully for the determination of CC in water samples without applying any sample pretreatment.

Differential Pulse Voltammetric Determination of Piroxicam on Lanthanide Ferric Oxide Nanoparticles-Carbon Paste Modified Electrode

2018 ◽  
Vol 14 (3) ◽  
pp. 271-276 ◽  
Author(s):  
Isaac Yves Lopes de Macedo ◽  
Morgana Fernandes Alecrim ◽  
Luane Ferreira Garcia ◽  
Aparecido Ribeiro de Souza ◽  
Wallans Torres Pio dos Santos ◽  
...  
Keyword(s):  
Modified Electrode ◽  
Ferric Oxide ◽  
Differential Pulse ◽  
Voltammetric Determination ◽  
Oxide Nanoparticles ◽  
Carbon Paste ◽  
Carbon Paste Modified Electrode

scholarly journals Square-wave voltammetric determination of rutin in pharmaceutical formulations using a carbon composite electrode modified with copper (II) phosphate immobilized in polyester resin

2012 ◽  
Vol 48 (4) ◽  
pp. 639-649 ◽  
Author(s):  
Kellen Heloizy Garcia Freitas ◽  
Orlando Fatibello-Filho ◽  
Ivanildo Luiz de Mattos
Keyword(s):  
Modified Electrode ◽  
Composite Electrode ◽  
Polyester Resin ◽  
Pharmaceutical Formulations ◽  
Carbon Composite ◽  
X Ray ◽  
Square Wave ◽  
Wave Voltammetry ◽  
Carbon Composite Electrode

A carbon composite electrode modified with copper (II) phosphate immobilized in a polyester resin (Cu3(PO4)2-Poly) for the determination of rutin in pharmaceutical samples by square-wave voltammetry is described herein. The modified electrode allows the determination of rutin at a potential (0.20 V vs. Ag/AgCl (3.0 mol L-1 KCl)) lower than that observed at an unmodified electrode. The peak current was found to be linear to the rutin concentration in the range from 9.9 × 10-8 to 2.5 × 10-6 mol L-1, with a detection limit of 1.2×10-8 mol L-1. The response of the electrode was stable, with no variation in baseline levels within several hours of continuous operation. The surface morphology of the modified electrode was characterized by scanning electron microscopy (SEM) and energy dispersive X-ray (EDX) system. The results obtained are precise and accurate. In addition, these results are in agreement with those obtained by the chromatographic method at a 95% confidence level.

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