Synthesis of new quinoxalinophenazinediones and tetrahydrobenzodipyrrolotetrones of biological interest
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AbstractThe reaction of two equivalents of sodium azide with diarylaminodibromo-p-benzoquinone (I) in DMF for 15–24 h produced quinoxalinophenazinediones together with a byproduct identified as diarylaminodiaminobenzoquinone. On the other hand, the reaction of bromanil with active methylenes, such as diethyl malonate and ethyl acetoacetate, resulted in disubstitution products which, on treatment with primary amines, cyclized into benzodipyrroletetrones. Comparative antifungal and antibacterial studies were made.
1988 ◽
Vol 43
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pp. 343-346
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2004 ◽
Vol 59
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pp. 380-385
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1965 ◽
Vol 48
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pp. 515-525
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1999 ◽
Vol 173
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pp. 249-254
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1969 ◽
Vol 27
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pp. 6-7
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1980 ◽
Vol 38
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pp. 30-33
2005 ◽
Vol 19
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pp. 129-132
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