scholarly journals Instrumental Assessment of the Face Skin Aging in Women

2018 ◽  
Vol 19 (3) ◽  
pp. 223-228 ◽  
Author(s):  
Natalia Evgenievna Manturova ◽  
Victor Aleksandrovich Stupin ◽  
Galina Olegovna Smirnova ◽  
Ekaterina Vladimirovna Silina

Abstract The aim of this study is to conduct several non-invasive methods for assessing the level of circulatory disturbance, elasticity and aging of skin in patients of different age groups in order to expand the diagnostic capabilities and evaluate the effectiveness of current research in aesthetic medicine. Clinical and instrumental exploration of 160 women aged 17 to 75 years with varying degrees of involutional skin changes was carried out. To objectify the assessment of skin condition, in all group of patients modern instrumental methods were used, such as: elastometry, ultrasound examination of the skin, laser Doppler flowmetry, transcutaneous oxygen tension. Concurrent implementation of several non-invasive methods for assessing the level of circulatory disturbance, elasticity and aging of the skin, allowed us to find new possibilities for studying the functional state of the skin. These methods extend the possibilities of ultrasonic research methods used today in aesthetic cosmetology. The obtained comparative data of elastometry, ultrasonography, laser Doppler flowmetry and transcutaneous oximetry in patients of different age groups showed the presence of elasticity and structure defect, skin thickness and subcutaneous fat, as well as microcirculation changes since 25 years and marked changes after 40 years.

1987 ◽  
Vol 11 (2) ◽  
pp. 80-84 ◽  
Author(s):  
S. L. E. Fairs ◽  
R. O. Ham ◽  
B. A. Conway ◽  
V. C. Roberts

Accurate and objective assessment of amputation level in the lower limb plays an important role in patient management. Laser Doppler flowmetry (LDF) is a new and noninvasive technique for skin blood flow measurement and has been used pre-operatively in 25 patients undergoing amputation for vascular disease and in five normal controls. Baseline flux measurements were made at room temperature on the medial aspect of legs and then again after local heating of the skin for five minutes. Transcutaneous oxygen measurements were made at the same site for comparison and amputation level in patients selected on this basis. Significant differences (p<0.001) in TcPO2 values were found between controls (10.9±0.5kPa), below-knee (BK) amputees (6.0±1.5kPa) and above-knee (AK) amputees (1.5±0.6kPa). Baseline LDF flux did not differ significantly between any group. Heated flux values did however show a significant difference (p<0.005) between controls (52.4±23.5) and both BK (20.6±9.2) and AK groups (8.1±7.7) and also between the amputee groups. The relative increase in flux (heated flux/baseline flux) differed significantly between the BK (3.3±1.5) and AK (1.2±0.3) groups (p<0.001) and between these two and the controls (11.2±5.4) (p<0.001). The correlation between relative increase in flux and TcPO2 was 0.7 (p<0.001). It is concluded that laser Doppler flowmetry used in conjunction with thermal stressing could provide a quick, simple and non-invasive method for objectively determining amputation level in the lower limb.


1988 ◽  
Vol 74 (2) ◽  
pp. 119-121 ◽  
Author(s):  
C. Orlandi ◽  
C. J. Dunn ◽  
L. G. Cutshaw

1. A non-invasive method is described for the assessment of angiogenesis in chronic inflammation using laser-Doppler flowmetry. 2. Significant increases in capillary blood flow were seen on days 5 and 7 after induction of subcutaneous granulomatous lesions, as compared with control skin. 3. Changes in blood flow were accompanied by changes in pulsatile flow pattern and by an intense angiogenic response observed by light microscopy. 4. The potential application of laser-Doppler flowmetry to quantitative and qualitative studies of evolving angiogenesis in pathological responses is discussed.


Author(s):  
Н.П. Теплюк ◽  
С.В. Лебедева

Цель работы - оценка изменений функционального состояния микроциркуляторного русла, изучение особенностей морфологических параметров кожи неинвазивными методами исследования при различных морфотипах старения. В исследовании приняли участие 55 человек 35-65 лет с инволюционными изменениями нижней трети лица. Выделены четыре морфотипа старения, в зависимости от которых пациенты были разделены на группы: 1-я - 19 пациенток с деформационным типом; 2-я - 17 пациенток с усталым; 3-я - 8 пациенток с мелкоморщинистым; 4-я - 11 пациенток со смешанным морфотипом. Для изучения состояния кожи использовали лазерную допплеровскую флоуметрию и УЗИ кожи (22 Mhz). Методом лазерной допплеровской флоуметрии выявлены достоверные изменения при сравнении показателей микроциркуляции и ультразвуковым методом исследования кожи - деформационного и мелкоморщинистого типов (p<0,05). У деформационного и смешанного типов наблюдали преимущественно атонический тип микроциркуляции (9,42±3,71 и 9,56±2,31 перф. ед. соответственно), а при мелкоморщинистом - спастический тип (7,86±1,6 перф. ед.), при усталом морфотипе показатель микроциркуляции был в пределах нормы (7,86±1,6 перф. ед.). Данные УЗИ кожи позволили выявить у пациенток с деформационным морфотипом старения наиболее высокие значения толщины эпидермиса (125,94±27,84 мкм), дермы (1 439±118,11 мкм), плотности дермы (12±2,59 у. е.) по сравнению с толщиной эпидермиса (85±22,01 мкм), толщиной дермы (1 130±68,55 мкм) и плотностью дермы (7,87±2,1 у. е.) при мелкоморщинистом морфотипе старения. The purpose of the work is to assess changes in the functional state of the microvasculature, study of the features of the morphological parameters of the skin by non-invasive research methods for various morphotypes of aging. The study involved 55 patients with involutional changes in the lower third of the face aged 35 to 65 years, included according with the inclusion and exclusion criteria. 4 morphotypes of aging were identified, depending on which patients were divided into corresponding groups: 1 - 19 patients with deformational type, 2 - 17 with tired type, 3 - 8 with fine wrinkled type, 4 - 11 with mixed morphotype of aging. To study the condition of the patients’ skin, laser Doppler flowmetry and ultrasound examination of the skin (22 Mhz) were used. The method of laser Doppler flowmetry revealed significant changes when comparing microcirculation indices and the ultrasound method for examining deformational and fine wrinkled type (p<0,05). In the deformational type and mixed type, a predominantly atonic type of microcirculation was observed (9,42±3,71 and 9,56±2,31 perf. u., respectively), and in fine wrinkled spastic type of microcirculation (7,86±1,6 perf. u.), in the oral morphotype the microcirculation index was within the normal range of 7,86±1,6 perf. u. The data of ultrasound examination of the skin made it possible to reveal in the deformational morphotype of aging high values of the thickness of the epidermis (125,94±27,84 μm), the dermis (1 439±118,11 μm) and the density of the dermis (12±2,59 a. u.) compared with the thickness of the epidermis 85±22,01 μm, the thickness of the dermis (1 130±68,55 μm) and the density of the dermis (7,87±2,1 c. u.) in the fine wrinkled morphotype of aging.


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