scholarly journals COVID-19. Liver damage – visualization features and possible causes

2020 ◽  
Vol 24 (3) ◽  
pp. 26-36
Author(s):  
A. S. Vinokurov ◽  
M. V. Nikiforova ◽  
A. A. Oganesyan ◽  
O. O. Vinokurova ◽  
A. L. Yudin ◽  
...  

Item. To evaluate the features of CT imaging of the liver and the possible causes of pathological changes in COVID-19.Materials and methods. An analysis of the literature and our own data on the features of CT imaging of the liver in combination with biochemical analyzes in patients with COVID-19 was performed. The main possible causes of changes in the liver, as well as symptoms with CT, are examined.Results. The main target of the new SARS-CoV-2 coronavirus is the respiratory system. But among patients with COVID-19, along with damage to the central nervous system, myocardium, and intestines, cases of liver damage or dysfunction have been reported. This is expressed in an increase in biochemical markers of liver damage, as well as in a diffuse decrease in its density during CT, which is usually observed in the acute stage of the disease.

Author(s):  
Andrea Pilotto ◽  
Silvia Odolini ◽  
Masciocchi S Stefano ◽  
Agnese Comelli ◽  
Irene Volonghi ◽  
...  

AbstractCovid-19 infection has the potential for targeting the central nervous system and several neurological symptoms have been described in patients with severe respiratory distress. Here we described the case of a 60-year old subject with SARS-CoV-2 infection but only mild respiratory abnormalities who developed an akinetic mutism due to encephalitis. MRI was negative whereas EEG showed generalized theta slowing. CSF analyses during the acute stage were negative for SARS-CoV-2, positive for pleocytosis and hyperproteinorrachia, and showed increased IL-8 and TNF-α concentrations while other infectious or autoimmune disorders were excluded. A progressive clinical improvement along with a reduction of CSF parameters was observed after high-dose steroid treatment, thus arguing for an inflammatory-mediated brain involvement related to Covid-19.


2016 ◽  
pp. 31-34
Author(s):  
Terrence D. Lagerlund

The variety of clinical neurophysiological studies corresponds to a variety of structural generators in the body, including muscles, sweat glands, peripheral nerves, and various components of the central nervous system. Each structural generator may have associated with it several different types of physiological potential. This chapter reviews the generators of electrophysiological potentials in terms of basic cellular electrophysiology and the anatomical structures that generate electrophysiological potentials of clinical interest. Knowledge of the generators of the potentials recorded in clinical neurophysiological studies is helpful in understanding the characteristics and distribution of the recorded potentials and is the first step in correlating the alterations seen in disease states with the pathological changes demonstrated in the underlying generators.


Parasitology ◽  
1955 ◽  
Vol 45 (1-2) ◽  
pp. 31-40 ◽  
Author(s):  
J. F. A. Sprent

A wide variety of nematode species have been observed to invade the central nervous system. They may be located in the meningeal spaces or may penetrate into the tissues of the brain and spinal cord.The pathological changes resulting from invasion of the central nervous system are influenced by the route of entry, the size and the mobility of the parasite. They may be diffuse or focal and may include haemorrhage, degenerative changes, cellular infiltration and glial proliferation. Such changes may or may not be observed in close association with the parasite.Symptoms indicating involvement of the central nervous system have long been associated with nematode infections outside the central nervous system. The pathogenesis of these symptoms is obscure, but they may possibly be of allergic origin.The direct pathological effects on the central nervous system are mainly the result of trauma and are directly proportional to the size and activity of the parasite. The possibility that nematodes may transport viruses into the central nervous system is briefly discussed.


2014 ◽  
Vol 27 (1) ◽  
pp. 14-16
Author(s):  
Andrzej Dybala ◽  
Monika Dyczko ◽  
Boguslaw Makaruk ◽  
Pawel Kicinski ◽  
Elzbieta Bartoszek ◽  
...  

Abstract Central sleep apnea (CSA) is a disease characterized by repetitive episodes of the socalled central apneas during sleep. The disease has a very complex etiology. In clinical practice, the most important causes of CSA are disorders of the central nervous system, congestive heart failure or certain pathological changes of the respiratory muscles. We present a case of a 43-year-old male with severe CSA, who was successfully treated with BiPAP ST equipment.


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