scholarly journals SELECTION OF PATIENTS WITH CONCOMITANT CHRONIC OBSTRUCTIVE DISEASE FOR ANATOMICAL RESECTIONS IN LUNG CANCER (review of literature)

2019 ◽  
Vol 178 (5) ◽  
pp. 121-126
Author(s):  
A. L. Akopov ◽  
S. D. Gorbunkov ◽  
A. I. Romanikhin ◽  
M. G. Kovalev

The analysis of literature on the possibility of performing anatomical pulmonary resections in patients with concomitant COPD was performed. According to most researchers, FEV1 and DL (CO) more than 80 % indicated a high probability of an uncomplicated postoperative period after any anatomical resection of the lung. If the specified parameters were less than 80 %, additional studies were required: functional tests (6-minute walk test, staircase test), stress testing, calculation of predicted postoperative values of respiratory function, and, if necessary, lung scintigraphy could be performed to study regional respiratory function. The decision about the possibility and need for surgical treatment should have been made individually at the threshold values of these parameters. At the same time, there is currently no system for assessing the risk of postoperative complications for a particular patient, based on all the information about it, which represents the potential for further research.The authors declare no conflict of interest.The authors confirm that they respect the rights of the people participated in the study, including obtaining informed consent when it is necessary, and the rules of treatment of animals when they are used in the study. Author Guidelines contains the detailed information.

2021 ◽  
Vol 9 (4) ◽  
pp. 553-558
Author(s):  
Aleksey V. Kosyakov ◽  

BACKGROUND: Considering the economic costs of managing patients with chronic obstructive pulmonary disease (COPD), as well as the high mortality and disability rate, it is necessary to improve the diagnosis of the disease, to look for new approaches to assessing the functional status of patients. AIM: Is to study the functional status of patients with COPD. MATERIALS AND METHODS: A comprehensive approach was applied to assess the functional status of patients: the data of the 6-minute walk test (6MWT), heart rate variability (HRV) was studied, ergoreflex was assessed according to HRV data. 64 patients with COPD and 41 male volunteers without respiratory diseases older than 40 years were examined. Statistical processing of the obtained results was carried out using the licensed package of applied statistical programs Excel 2010 and Statistica 10. RESULTS: The group of patients with COPD and the respondents of the control group were comparable in terms of body mass index, heart rate, respiratory rate, index of indicators of activity of regulatory systems (p > 0.05). As expected, during the 6MWT, differences were obtained between the studied groups in terms of the distance covered (p < 0.01). Similarly, the results of the study of the function of external respiration showed a statistically significant difference in all the studied parameters (p < 0.01). The results obtained confirmed the presence of impaired respiratory function in the group of patients with COPD. Analysis of HRV values, when conducting a test with external peripheral vascular occlusion, confirmed ergoreflex hyperactivity in patients with COPD. CONCLUSION: The integration of methods for routine clinical diagnostics of patients condition (spirometry, 6-minute walk test, assessment of autonomic status) and the introduction of the study of ergoreflex activity made it possible to expand the understanding of the functional state of patients with COPD and is of great interest for further research.


2021 ◽  
Author(s):  
Ganghee Chae ◽  
Eun Jae Ko ◽  
Sei Won Lee ◽  
Hyun Jung Kim ◽  
Sang Gyu Kwak ◽  
...  

Abstract Background: The 6-minute walk test (6MWT) and incremental shuttle walk test (ISWT) are valid and reliable measures to assess exercise capacity of patients with chronic obstructive pulmonary disease (COPD). However, the comparison of correlation between peak oxygen uptake (peak VO2) and 6MWT or ISWT distance has not been investigated. We aimed to investigate the correlation between peak VO2 and 6MWT and ISWT distances in patients with COPD through a meta-analysis.Methods: We systematically searched MEDLINE, Scopus, Embase, and the Cochrane Library up to June 30, 2020 for studies comparing the correlation of peak VO2 with either 6MWT or ISWT in patients with COPD. Meta-analysis was performed with R software using a fixed-effect model. We compared the correlation coefficient and measured the heterogeneity using I2 statistics. Results: We identified 12 studies involving 746 patients. Meta-analysis showed a significant correlation between peak VO2 and 6MWT and ISWT distances (6MWT: r = 0.65, 95% CI: 0.61 to 0.70; ISWT: r = 0.81, 95% CI: 0.74 to 0.85; p < 0.0001). The heterogeneity was lower in ISWT than in 6MWT (6MWT: I2 = 56%, p = 0.02; ISWT: I2 = 0%, p = 0.71). Subgroup analysis showed a higher correlation coefficient in the low exercise capacity group than in the high exercise capacity group in both field tests. No risk of publication bias was identified.Conclusions: 6MWT and ISWT were significantly correlated with peak VO2. The findings suggest that ISWT had a stronger correlation with peak VO2 than did 6MWT in patients with COPD.Trial registration: CRD 42020200139 at crd.york.ac.uk/prospero/


2020 ◽  
Vol 14 (4) ◽  
pp. 364-369
Author(s):  
Nikita Gurbani ◽  
Juan Marco Figueira Gonçalves ◽  
Miguel Ángel García Bello ◽  
Ignacio García‐Talavera ◽  
Andrea Afonso Díaz

Author(s):  
M.A. Panova ◽  
◽  
Y.Y. Gorblyansky ◽  
E.P. Kontorovich

Abstract: Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity worldwide. In patients with COPD, the level of physical activity is reduced, which is associated with an increased risk of adverse outcomes of this disease. At the same time, the problem of physical activity in patients with occupational COPD has been little studied. There are a number of factors affecting the physical activity of patients with COPD, one of which is exercise tolerance. To evaluate it, special tests are used, one of which is the 6-minute walk test. The aim of the study was to compare the characteristics of exercise tolerance in patients with COPD and occupational COPD. We analyzed the case histories of patients with an established diagnosis of COPD undergoing inpatient treatment and pulmonary rehabilitation. Patients (n - 35) were divided into two groups. The first group - patients with generalized COPD (n -17), men from 55.0 ± 20.0 years. The second group is patients with occupational COPD (n-18), men from 55.0 ± 20.0 years. All patients underwent a 6-minute walk test. The analysis of the results has been carried out. On average, patients with occupational COPD walked a shorter distance in 6 minutes, although these differences were not significant. In the group of occupational COPD, a larger percentage of patients had a worse prognosis in the prevention of cardiovascular complications. The 6-minute walk test can be used in combination with other assessment methods at the stages of pulmonary rehabilitation in order to determine the prognosis, determine the tolerance of physical activity.


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