scholarly journals LDF method capabilities in the estimation of age-related features of the microcirculation system functioning

2018 ◽  
Vol 17 (3) ◽  
pp. 80-86 ◽  
Author(s):  
I. A. Tikhomirova ◽  
N. V. Baboshina ◽  
S. S. Terekhin

The aim of this study was to assess the age-related features of the functioning of the microcirculation system using the LDF method. The estimation of parameters of microcirculation was performed in practically healthy persons of mature age in a one-stage study and in a prospective study in children aged 8 to 11 years. Stable indices of microcirculation were recorded at different stages of adulthood with maximal values in the middle of this age period. In the prospective study, significant changes in the functioning of the microcirculation system in the period from 9 to 10 years, indicating the beginning of the transition to the pubertal period, were noted. The revealed age-specific features of the functioning of the microcirculation system are due to the level of metabolic activity of the body.

2021 ◽  
pp. 247412642199705
Author(s):  
Halward M.J. Blegen ◽  
Samuel D. Hobbs ◽  
Reggie Taylor ◽  
Andrew L. Plaster ◽  
Paul M. Drayna

Purpose: Optical coherence tomography (OCT) is useful in diagnosing and monitoring retinal pathology such as age-related macular degeneration, diabetic macular edema (DME), central serous chorioretinopathy, and epiretinal membrane, among others. This study compared the ability of horizontal (H) 25-, 13-, and 7-cut macular OCT vs 24-, 12-, and 6-cut radial (R) macular OCT in identifying various macular pathology. Methods: This was a prospective study of 161 established patients evaluated at Wilford Hall Eye Center Retina Clinic between September and October of 2019. Pathology included age-related macular degeneration, central serous chorioretinopathy, DME, and epiretinal membrane, among others. Patients obtained 25-, 13-, and 7-cut H raster OCT as well as 24-, 12-, and 6-cut R OCT. Primary outcomes were sensitivity in detecting macular fluid and each macular abnormality. Results: The 24-cut radial (R24) OCT equally or out-performed the H25 (horizontal 25-cut OCT) in detecting macular fluid across all pathological groups. Generally, a higher number of cuts correlated with better detection of fluid. In detecting any macular abnormalities, H25, R24, and R12 had 100% sensitivity. R6 OCT had near 100% sensitivity across all groups, except for DME (95%). Overall, R OCT had better sensitivity (0.960) than H OCT (0.907) in detecting macular pathology. Conclusions: R outperformed H macular OCT in detecting fluid and other abnormalities. Clinically, both scanning patterns can be used by ophthalmologists in diagnosis and management of commonly encountered macular diseases. Technicians may be able to use a variety of these scans to screen for pathology prior to physician evaluation.


2019 ◽  
Vol 39 (6) ◽  
pp. 875-882 ◽  
Author(s):  
Renzo Guarnieri ◽  
Dario Di Nardo ◽  
Gianfranco Gaimari ◽  
Gabriele Miccoli ◽  
Luca Testarelli

1999 ◽  
Vol 9 (3) ◽  
pp. 172-177 ◽  
Author(s):  
Umed A Ajani ◽  
William G Christen ◽  
Joann E Manson ◽  
Robert J Glynn ◽  
Debra Schaumberg ◽  
...  

2018 ◽  
Vol 35 (7-8) ◽  
pp. 190-3
Author(s):  
Johnwan Usman ◽  
Irfan Abdullah ◽  
Muhazar Muhazar ◽  
Atan Baas Sinuhaji ◽  
A. H. Sutanto

A prospective study on steatocrit value in full-term or preterm newborn babies of~ 2 days of age in Dr. Pimgadi Hospital, Medan is reported. This study was conducted from December 7, 1992, to February 7, 1993; there were 72 newborn babies (37 males and 35 females). The body weight was> 2500 gin 60 babies and s. 2500 gin 12 babies. The median steatocrit value in babies with body weight of> 2500 g was 9%, and it was 32% in babies less than 2500 g of body weight. The proportion of babies with > 25% steatocrit value was larger in babies less than 2500 g than that in 2500 g by the diet patterns of breast milk, breast milk and milk formula, milk formula. The proportion of babies with < 25% steatocrit value was higher in babies with body weight of< 2500 g than that in babies > 2500 g for those who had either breast milk, breast milk and milk formula or milk formula. There was significant difference (p<0,05) in the steatocrit levels between babies with the body weight of > 2500 g and those who had body weight of ≤ 2500 g.


2014 ◽  
Vol 46 (12) ◽  
pp. 2244-2252 ◽  
Author(s):  
JONATHAN A. MITCHELL ◽  
MATTEO BOTTAI ◽  
YIKYUNG PARK ◽  
SIMON J. MARSHALL ◽  
STEVEN C. MOORE ◽  
...  

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