Rice bran enzymatic extract reduces hyperlipidemia and related hepatic steatosis in ApoE−/− mice

2015 ◽  
Vol 3 (Suppl. 2) ◽  
pp. A1.19
Author(s):  
Cristina Pérez Ternero
Keyword(s):  
Hepatic Steatosis ◽  
Rice Bran ◽  
Enzymatic Extract

scholarly journals Bioavailability of the ferulic acid-derived phenolic compounds of a rice bran enzymatic extract and their activity against superoxide production

2017 ◽  
Vol 8 (6) ◽  
pp. 2165-2174 ◽  
Author(s):  
Cristina Perez-Ternero ◽  
Alba Macià ◽  
Maria Alvarez de Sotomayor ◽  
Juan Parrado ◽  
Maria-Jose Motilva ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Ferulic Acid ◽  
Rice Bran ◽  
Superoxide Production ◽  
Enzymatic Extract

Rice bran is an exceptional source of such antioxidant molecules as γ-oryzanol and ferulic acid, but their bioavailability and metabolism within this matrix remain unknown.

Preparation of a rice bran enzymatic extract with potential use as functional food

2006 ◽  
Vol 98 (4) ◽  
pp. 742-748 ◽  
Author(s):  
Juan Parrado ◽  
Esther Miramontes ◽  
Maria Jover ◽  
Juan Fco Gutierrez ◽  
Laura Collantes de Terán ◽  
...  
Keyword(s):  
Rice Bran ◽  
Functional Food ◽  
Enzymatic Extract ◽  
Potential Use

Atherosclerosis-related inflammation and oxidative stress are improved by rice bran enzymatic extract

2016 ◽  
Vol 26 ◽  
pp. 610-621 ◽  
Author(s):  
Cristina Perez-Ternero ◽  
Beatriz Bermudez Pulgarin ◽  
Maria Alvarez de Sotomayor ◽  
Maria Dolores Herrera
Keyword(s):  
Oxidative Stress ◽  
Rice Bran ◽  
Enzymatic Extract ◽  
And Oxidative Stress

scholarly journals Standardized rice bran extract improves hepatic steatosis in HepG2 cells and ovariectomized rats

2020 ◽  
Vol 14 (6) ◽  
pp. 568
Author(s):  
Dong Wook Lim ◽  
Hyejin Jeon ◽  
Minji Kim ◽  
Minseok Yoon ◽  
Jonghoon Jung ◽  
...  
Keyword(s):  
Hepatic Steatosis ◽  
Rice Bran ◽  
Hepg2 Cells ◽  
Ovariectomized Rats ◽  
Rice Bran Extract

scholarly journals Optimization, antioxidant activity and bile salts adsorption capacity of the aqueous enzymatic extract from rice bran

2018 ◽  
Vol 36 (No. 4) ◽  
pp. 333-343
Author(s):  
Wang Yuxin ◽  
Yu Guoping ◽  
Zang Xiaodan ◽  
Ye Fei
Keyword(s):  
Rice Bran ◽  
Antioxidant Activities ◽  
Sodium Taurocholate ◽  
Value Added ◽  
Sodium Deoxycholate ◽  
Extraction Temperature ◽  
High Concentration ◽  
Enzymatic Extract ◽  
Antioxidant Power ◽  
Solid Ratio

The optimum extraction conditions of the aqueous enzymatic extract from rice bran (AEERB) were evaluated with respect to γ-oryzanol content and ferric reducing/antioxidant power (FRAP) activity by using response surface methodology. The results showed that the effect of the extraction temperature on γ-oryzanol content and FRAP activity was the most significant. The optimal conditions were determined as follows: Trypsin, 453 U/g at 56°C and pH 7.9 for 2 h at a liquid/solid ratio of 7 : 1. The corresponding γ-oryzanol content and FRAP activity were 0.1749 mg/g and 0.5043 mmol FeSO<sub>4</sub>/g, respectively. The antioxidant activities of AEERB were comparable with 2,6-di-tert-buty-4-methylphenol (BHT) or ascorbic acid (AA) at the high concentration. Furthermore, the binding capacities of AEERB to sodium taurocholate and sodium deoxycholate were 24.96 and 13.63 µmol/100 mg, respectively. The results indicated that AEERB is a promising method for developing and applying a value-added RB product.

Food supplementation with rice bran enzymatic extract prevents vascular apoptosis and atherogenesis in ApoE−/− mice

2015 ◽  
Vol 56 (1) ◽  
pp. 225-236 ◽  
Author(s):  
C. Perez-Ternero ◽  
M. D. Herrera ◽  
U. Laufs ◽  
M. Alvarez de Sotomayor ◽  
C. Werner
Keyword(s):  
Rice Bran ◽  
Food Supplementation ◽  
Enzymatic Extract

Rice bran enzymatic extract reduces atherosclerotic plaque development and steatosis in high-fat fed ApoE−/− mice

Nutrition ◽  
2017 ◽  
Vol 37 ◽  
pp. 22-29 ◽  
Author(s):  
Cristina Perez-Ternero ◽  
Carmen Claro ◽  
Juan Parrado ◽  
Maria Dolores Herrera ◽  
Maria Alvarez de Sotomayor
Keyword(s):  
Rice Bran ◽  
Atherosclerotic Plaque ◽  
High Fat ◽  
Enzymatic Extract ◽  
Plaque Development

Aqueous Enzymatic Method for Preparing the Mixed Extract with Antioxidant Activity from Rice Bran

2013 ◽  
Vol 781-784 ◽  
pp. 792-798 ◽  
Author(s):  
An Min Sun ◽  
Guo Ping Yu ◽  
Yu Xin Wang ◽  
Ji Bian ◽  
Rao Fu ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Free Radicals ◽  
Rice Bran ◽  
Lipase Activity ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Natural Antioxidants ◽  
Degree Of Hydrolysis ◽  
Enzymatic Extract ◽  
Functional Components

The preparation, approximate composition, degree of hydrolysis (DH), lipase activity and antioxidant capacity (including the ability of scavenging DPPH and ABTS free radicals) were determined for various of aqueous enzymatic extract (AEE) obtained from rice bran (RB) using alcalase (A), trypsin (T), papain (Pn), neutrase (N) and protamex (Px). Peptides and γ-oryzanol are the major functional components of AEE. Generally, the protein yield varied with the type of enzyme used in the order of T>Pn>N>Px>A. Both trypsin and alcalase extracts exhibit a higher level of γ-oryzanol than other enzymes. Lipase activity was measured using the 4-Nitrophenyl Laurate (p-NPL) substrate method, and significantly different (P<0.05) lipase activity values ranging from 0.55 to 2.38 mU/mL were observed from five hydrolysates. Furthermore, two synthetic free radicals were used to evaluate the antioxidant activity of AEE. The alcalase extract (at 4.35±0.15mg protein/mL AEE) shows the greatest scavenging rate (28.42%) of DPPH, but trypsin extract has highest ABTS radical-scavenging activity of 94.05%. Data revealed trypsin was possible the most effective extractant under their optimal conditions. These results demonstrate that the product obtained from rice bran by different enzymatic digestions may contain bioactive components and might potentially be natural antioxidants. Meanwhile, the aqueous enzymatic extraction method can also improve the stability of the hydrolysates.

Food supplementation with rice bran enzymatic extract prevents vascular senescence and atherogenesis in APoE-/- mice

2015 ◽  
Vol 241 (1) ◽  
pp. e57
Author(s):  
C. Perez Ternero ◽  
C. Werner ◽  
J. Parrado ◽  
M. Alvarez de Sotomayor ◽  
M.D. Herrera ◽  
...  
Keyword(s):  
Rice Bran ◽  
Food Supplementation ◽  
Enzymatic Extract ◽  
Vascular Senescence
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