Characterization of the Noise Sources in a Rod-Airfoil Configuration by Means of Time-Resolved Tomographic PIV

Reynolds stress tensor and pressure-related turbulence transport terms measured by time-resolved tomographic-PIV

14th International Symposium on Particle Image Velocimetry ◽

10.18409/ispiv.v1i1.99 ◽

2021 ◽

Vol 1 (1) ◽

Author(s):

Jose Roberto Moreto ◽

Xiaofeng Liu

Keyword(s):

Flow Field ◽

Turbulent Flow ◽

Turbulent Flows ◽

High Speed ◽

Three Dimensional ◽

Time Resolved ◽

Tomographic Piv ◽

Piv Measurement ◽

Derivatives Of

Turbulence is inherently a three-dimensional and time dependent flow phenomenon (Pope, 2001). Because of the ubiquitous existence of turbulent flows in nature, accurate characterization of turbulent flows, either through experimental measurements or through direct numerical simulations, is of paramount importance for modeling turbulence (Liu and Katz, 2018). Since its inception in 1984 (Adrian, 1984), Particle Image Velocimetry (PIV), among several other conventional techniques used for turbulence measurements, has been a valuable tool for providing reliable experimental data for turbulence research. Several advancements in hardware such as high-speed cameras, together with innovative algorithms and procedures, have extended the scope of PIV to a variety of applications. Westerweel et al. (2013) point out in a recent review article that one of the main advantages of the PIV measurement is its unique ability in measuring quantitatively spatial derivatives of the flow field. With the development of Tomographic PIV introduced by Elsinga et al. (2006), it is now possible to measure simultaneously the distributions of three velocity components in a three-dimensional flow field, thus enabling us to measure all the velocity derivatives of a turbulent flow. However, for a thorough characterization of a turbulent flow, in addition to the velocity gradients, the instantaneous pressure distribution in the 3D flow field also needs to be measured.

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Time-resolved tomographic PIV and pressure measurement of a turbulent shear layer flow impinging on a cavity trailing corner

AIAA Scitech 2021 Forum ◽

10.2514/6.2021-0220 ◽

2021 ◽

Author(s):

Jose Moreto ◽

Xiaofeng Liu

Keyword(s):

Shear Layer ◽

Pressure Measurement ◽

Turbulent Shear ◽

Time Resolved ◽

Tomographic Piv ◽

Turbulent Shear Layer ◽

Layer Flow

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The Generation and Characterization of Ultrashort Electron Pulses and their Application to Time-Resolved Electron Diffraction.

10.21236/ada308231 ◽

1996 ◽

Author(s):

Peter M. Weber

Keyword(s):

Electron Diffraction ◽

Time Resolved ◽

Electron Pulses

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Characterization of a Novel FRET Probe in a Crowded Environment using Time-Resolved Anisotropy

Biophysical Journal ◽

10.1016/j.bpj.2016.11.1878 ◽

2017 ◽

Vol 112 (3) ◽

pp. 346a

Author(s):

Hannah Leopold ◽

Megan Currie ◽

Jacob Schwarz ◽

Arnold J. Boersma ◽

Erin D. Sheets ◽

...

Keyword(s):

Time Resolved ◽

Crowded Environment

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Characterization of Noise Level Inside a Vehicle under Different Conditions

Sensors ◽

10.3390/s20092471 ◽

2020 ◽

Vol 20 (9) ◽

pp. 2471 ◽

Cited By ~ 3

Author(s):

Daniel Flor ◽

Danilo Pena ◽

Luan Pena ◽

Vicente A. de Sousa ◽

Allan Martins

Keyword(s):

Regression Analysis ◽

Noise Level ◽

Acoustic Noise ◽

Experimental Setup ◽

Strongly Correlated ◽

Noise Levels ◽

Noise Sources ◽

Statistical Tools ◽

Window Position

Vehicular acoustic noise evaluations are a concern of researchers due to health and comfort effects on humans and are fundamental for anyone interested in mitigating audio noise. This paper focuses on the evaluation of the noise level inside a vehicle by using statistical tools. First, an experimental setup was developed with microphones and a microcomputer located strategically on the car’s panel, and measurements were carried out with different conditions such as car window position, rain, traffic, and car speed. Regression analysis was performed to evaluate the similarity of the noise level from those conditions. Thus, we were able to discuss the relevance of the variables that contribute to the noise level inside a car. Finally, our results revealed that the car speed is strongly correlated to interior noise levels, suggesting the most relevant noise sources are in the vehicle itself.

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KD determination from time-resolved experiments on live cells with LigandTracer and reconciliation with end-point flow cytometry measurements

European Biophysics Journal ◽

10.1007/s00249-021-01560-2 ◽

2021 ◽

Author(s):

Diana Spiegelberg ◽

Jonas Stenberg ◽

Pascale Richalet ◽

Marc Vanhove

Keyword(s):

Flow Cytometry ◽

Live Cells ◽

Time Resolved ◽

Surface Receptors ◽

Full Characterization ◽

End Point ◽

Titration Curves ◽

Kinetics Of

AbstractDesign of next-generation therapeutics comes with new challenges and emulates technology and methods to meet them. Characterizing the binding of either natural ligands or therapeutic proteins to cell-surface receptors, for which relevant recombinant versions may not exist, represents one of these challenges. Here we report the characterization of the interaction of five different antibody therapeutics (Trastuzumab, Rituximab, Panitumumab, Pertuzumab, and Cetuximab) with their cognate target receptors using LigandTracer. The method offers the advantage of being performed on live cells, alleviating the need for a recombinant source of the receptor. Furthermore, time-resolved measurements, in addition to allowing the determination of the affinity of the studied drug to its target, give access to the binding kinetics thereby providing a full characterization of the system. In this study, we also compared time-resolved LigandTracer data with end-point KD determination from flow cytometry experiments and hypothesize that discrepancies between these two approaches, when they exist, generally come from flow cytometry titration curves being acquired prior to full equilibration of the system. Our data, however, show that knowledge of the kinetics of the interaction allows to reconcile the data obtained by flow cytometry and LigandTracer and demonstrate the complementarity of these two methods.

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Time-Resolved Spectroscopic Study of N,N-Di(4-bromo)nitrenium Ions in Selected Solutions

Molecules ◽

10.3390/molecules23123182 ◽

2018 ◽

Vol 23 (12) ◽

pp. 3182 ◽

Cited By ~ 5

Author(s):

Lili Du ◽

Xin Lan ◽

Zhiping Yan ◽

Ruixue Zhu ◽

David Phillips

Keyword(s):

Transient Absorption ◽

Direct Detection ◽

Reaction Pathway ◽

Addition Reactions ◽

Time Resolved ◽

Nitrenium Ions ◽

Future Studies ◽

Nitrenium Ion ◽

Design Time

Nitrenium ions are important reactive intermediates in chemistry and biology. In this work, femtosecond and nanosecond transient absorption (fs-TA and ns-TA) along with nanosecond time-resolved resonance Raman (ns-TR3) experiments were employed to examine the photochemical pathways of N-(4,4′-dibromodiphenylamino)-2,4,6-trimethylpyridinium BF4− (salt (DN) from just absorption of a photon of light to the production of the important N,N-di(4-bromophenyl)nitrenium ion 2. In acetonitrile (MeCN), the formation of halogenated diarylnitrenium ion 2 was observed within 4 ps, showing the vibrational spectra with strong intensity. The nucleophilic adduct reaction of ion 2 with H2O was also examined in aqueous solutions. The direct detection of the unique ortho adduct intermediate 3 shows that there is an efficient and exclusive reaction pathway for 2 with H2O. The results shown in this paper give new characterization of 2, which can be used to design time-resolved spectroscopy investigations of covalent addition reactions of nitrenium ions with other molecules in future studies.

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