Oxidative Stress Parameters as A Marker From Several Pathological Conditions in Cervical Mucus

2017 ◽  
Vol 8 (03) ◽  
Author(s):  
Nia Kania ◽  
Syarifudin Basri ◽  
Iskandar Thalib ◽  
Eko Suhartono
Keyword(s):  
Oxidative Stress ◽  
Hydrogen Peroxide ◽  
Pap Smear ◽  
Cervical Mucus ◽  
Advanced Oxidation Protein Products ◽  
Oxidative Stress Parameters ◽  
Pathological Conditions ◽  
Atypical Cells ◽  
Stress Parameters ◽  
Undetermined Significance

The objectives of this study were to measure several oxidative stress parameters in cervical mucous with several pathological conditions. The parameters are myeloperoxidase (MPO) activity, hydrogen peroxide (H2O2) and Advanced Oxidation Protein Products (AOPPs) levels. Seventy-six women with aged 20-45 years, who attend to Indonesian Cancer Association, Jakarta, Indonesia were enrolled in the study. Cervical mucus was taken from each patient, and after that, pap smear procedure is performed to determine the condition of each patient's cervix. According to the results of the pap smear, there are three cervical conditions, such as normal, mild chronic specific infection, chronic non-specific infection, and atypical cells of undetermined significance (ASCUS). A significant increase in MPO activity, H2O2, and AOPPs levels were observed in all group of patients, compared to normal patients. In conclusion, oxidative stress was involved in several pathological conditions in the uterine cervix, and the parameters measured in this study may be used as a marker in those conditions.

scholarly journals The Evaluation of Saliva Oxidative and Antioxidative Markers’ Levels in Adolescents with Gingival Inflammation

2019 ◽  
Vol 0 (0) ◽  
Author(s):  
Vesna Obradovic
Keyword(s):  
Oxidative Stress ◽  
Hydrogen Peroxide ◽  
Periodontal Disease ◽  
Control Group ◽  
World Population ◽  
Oral Diseases ◽  
Gingival Inflammation ◽  
Oxidative Stress Parameters ◽  
Whole Saliva ◽  
Stress Parameters

Abstract Periodontal disease is highly prevalent and affects 10%–15% of the world population. Salivary markers of oxidative stress and antioxidant status represent promising tool for research of oral diseases. Given the importance of reactive oxygen species (ROS) in the pathogenesis of periodontal disease, the aim of this study was to determine the association between oxidative stress parameters and periodontal disease gingivitis in adolescents. The study included a consecutive sample of 80 male and female participants referred to the Institute of Dentistry, Kragujevac, Serbia, as a result of periodontal problems or for routine control, aged 18 to 21, with definitive dentition as an inclusion criterion. Patients were divided into three groups depending on their gingival inflammation status. The first group was control group (n=20) with no gingival inflammation, the second group was with mild gingival inflammation (n=19), the third group was with moderate gingival inflammation (n=21) and the fourth group was with severe gingival inflammation (n=20). Oxidative stress parameters were measured in unstimulated whole saliva samples (superoxide anion radical, hydrogen peroxide, nitric oxide, index of lipid peroxidation, reduced gluthatione, catalase and superoxide dismutase). We have found increased levels of hydrogen peroxide and reduced glutathione in the saliva of patients with moderate levels of gingival inflammation, while the other markers were not significantly affected. In conclusion, oxidative stress plays a central role in the pathogenesis and the determination of oxidative and antioxidative levels could be a potent tool in controlling the development of gingivitis.

Does human myocardium show a gender dependent modification of oxidative stress parameters?

2014 ◽  
Vol 62 (S 01) ◽  
Author(s):  
K. Buschmann ◽  
Y. Gramlich ◽  
M. Oelze ◽  
A. Daiber ◽  
T. Münzel ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Human Myocardium ◽  
Oxidative Stress Parameters ◽  
Dependent Modification ◽  
Stress Parameters

Evaluation of oxidative stress parameters in subacute thyroiditis patients

2019 ◽  
Author(s):  
Murat Dağdeviren ◽  
Arzu Or Koca ◽  
Tolga Akkan ◽  
İhsan Ateş ◽  
Salim Neşelioğlu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Subacute Thyroiditis ◽  
Oxidative Stress Parameters ◽  
Stress Parameters

Omega-3 fatty acids and mood stabilizers alter behavioral and oxidative stress parameters in animals subjected to fenproporex administration

2016 ◽  
Vol 32 (2) ◽  
pp. 519-528 ◽  
Author(s):  
Lara M. Gomes ◽  
Milena Carvalho-Silva ◽  
Letícia J. Teixeira ◽  
Joyce Rebelo ◽  
Isabella T. Mota ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Mood Stabilizers ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Oxidative Stress Parameters ◽  
And Oxidative Stress ◽  
Stress Parameters

scholarly journals Time Course of Redox Biomarkers in COVID-19 Pneumonia: Relation with Inflammatory, Multiorgan Impairment Biomarkers and CT Findings

Antioxidants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1126
Author(s):  
Tijana Kosanovic ◽  
Dragan Sagic ◽  
Vladimir Djukic ◽  
Marija Pljesa-Ercegovac ◽  
Ana Savic-Radojevic ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Time Course ◽  
Redox Homeostasis ◽  
Original Data ◽  
Advanced Oxidation Protein Products ◽  
Oxidative Stress Parameters ◽  
Systemic Oxidative Stress ◽  
Dependent Relation ◽  
Organ Tissue ◽  
Insight Into

Although the original data on systemic oxidative stress in COVID-19 patients have recently started to emerge, we are still far from a complete profile of changes in patients’ redox homeostasis. We aimed to assess the extent of oxidative damage of proteins, lipids and DNA during the course of acute disease, as well as their association with CT pulmonary patterns. In order to obtain more insight into the origin of the systemic oxidative stress, the observed parameters were correlated with inflammatory biomarkers and biomarkers of multiorgan impairment. In this prospective study, we included 58 patients admitted between July and October 2020 with COVID-19 pneumonia. Significant changes in malondialdehyde, 8-hydroxy-2’-deoxyguanosine and advanced oxidation protein products levels exist during the course of COVID-19. Special emphasis should be placed on the fact that the pattern of changes differs between non-hospitalized and hospitalized individuals. Our results point to the time-dependent relation of oxidative stress parameters with inflammatory and multiorgan impairment biomarkers, as well as pulmonary patterns in COVID-19 pneumonia patients. Correlation between redox biomarkers and immunological or multiorgan impairment biomarkers, as well as pulmonary CT pattern, confirms the suggested involvement of neutrophils networks, IL-6 production, along with different organ/tissue involvement in systemic oxidative stress in COVID-19.

Behavior and oxidative stress parameters in rats subjected to the animal's models induced by chronic mild stress and 6-hydroxydopamine

2021 ◽  
Vol 406 ◽  
pp. 113226
Author(s):  
Talita Tuon ◽  
Sandra S. Meirelles ◽  
Airam B. de Moura ◽  
Thayse Rosa ◽  
Laura A. Borba ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Chronic Mild Stress ◽  
Mild Stress ◽  
Oxidative Stress Parameters ◽  
6 Hydroxydopamine ◽  
And Oxidative Stress ◽  
Stress Parameters
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