scholarly journals Hair transplantation in androgenetic alopecia

2021 ◽  
Vol 1 ◽  
pp. 20
Author(s):  
Kavish Chouhan ◽  
Gillian Roga
Keyword(s):  
Medical Therapy ◽  
Hair Loss ◽  
Androgenetic Alopecia ◽  
Hair Transplantation ◽  
Common Cause ◽  
The Past ◽  
Scarring Alopecia ◽  
Male Pattern

Androgenetic alopecia is the most common cause of non-scarring alopecia in men. Even though the past couple of years have seen significant advancements in the management of patterned hair loss. Medical therapy as a standalone treatment remains unsatisfactory and surgical restoration of hair has found to be extremely gratifying as far as male pattern hair loss is concerned. In this article, we will review the latest developments in the field of hair transplantation undertaken in androgenetic alopecia.

Asymmetry of the Receding Hairline in Men With Early Androgenetic Alopecia

2016 ◽  
Vol 20 (6) ◽  
pp. 546-549
Author(s):  
Reza Pashmineh Azar ◽  
Alexander Horst Thomas ◽  
Marcus Maurer ◽  
Gerd Lindner
Keyword(s):  
Hair Loss ◽  
Classification System ◽  
Quantitative Methods ◽  
Frontal Region ◽  
Androgenetic Alopecia ◽  
Hair Transplantation ◽  
Technical Improvement ◽  
Quick Assessment ◽  
Male Pattern

Background: The Norwood classification system is commonly used to ascertain the progress of androgenetic alopecia (AGA) with a robust and quick assessment, but it lacks precision in the frontal region, notably during the onset of male pattern hair loss. Objective: Due to the ongoing technical improvement in restorative hair transplantation practices, we aim to develop simple quantitative methods for measuring the progression of AGA. Methods: Here, we used a quantitative system to evaluate the progress of AGA of the frontal receding hairline in a case study with 41 patients. Results: We found subtle differences in the extent of frontotemporal regressions that were not captured by the Norwood classification system. The majority of patients exhibited significantly larger right-sided frontotemporal regressions. Conclusion: These results indicate that the quantification system used is a valuable tool in complementing the Norwood classification system to more precisely determine the recessing hairline characteristics in early stages of hair loss. Our findings also suggest that hairline regression in AGA-affected patients is asymmetrical, a hitherto unnoticed disorder-associated phenomenon with unknown biological causality.

Application and Approach to Hair Transplantation in Females

1997 ◽  
Vol 14 (2) ◽  
pp. 137-141
Author(s):  
Paul C. Cotterill
Keyword(s):  
Treatment Option ◽  
Hair Loss ◽  
Androgenetic Alopecia ◽  
Hair Transplantation ◽  
New Techniques ◽  
Inflammatory Dermatosis ◽  
Viable Treatment

Hair transplantation for females has become a much more viable treatment option because of recent improvements in technique employing micrografts and minigrafts as well as multiple-strip donor harvesting. The author describes how these new techniques are applied to the various types of transplantation in women, such as for androgenetic alopecia, traction alopecia, eyebrows, inactive inflammatory dermatosis, hair loss, and postrhytidectomy scarring. “Pearls,” to emphasize the contrast in the approach to the treatment of women with that of their male counterparts and the importance of assessing for realistic expectations, are described. A review of 827 females seen in consultation over the last 10 years showed that 70% of women with androgenetic alopecia were candidates for hair transplants.

scholarly journals Changes in the hair growth cycle in women with non-scarring alopecia

2019 ◽  
Vol 94 (5) ◽  
pp. 39-49
Author(s):  
A. A. Kubanov ◽  
Y. A. Gallyamova ◽  
O. A. Korableva
Keyword(s):  
Growth Factors ◽  
Growth Factor ◽  
Hair Loss ◽  
Reference Group ◽  
Growth Cycle ◽  
Punch Biopsy ◽  
Androgenetic Alopecia ◽  
Pharmacological Agents ◽  
Scarring Alopecia ◽  
Cycle Growth

One of the key elements in the pathophysiological process of androgenetic alopecia and telogen hair loss is the change of hair cycle. Growth factors controlling the development and cycle of the hair follicle have thus far been established. However, the role of growth factors in the pathogenesis of alopecia remains to be revealed.Objective.This study was aimed at investigating the expression of the VEGF, KGF, EGF and TGF-01 growth factors in women with androgenetic alopecia and telogen hair loss, as well as their role in the development of alopecia.Materials and methods. 60 female patients diagnosed with telogen hair loss (30 women) and androgenetic alopecia (30 women) were observed. In order to investigate the expression of the VEGF, KGF, EGF and TGF-01 growth factors, we conducted an immunofluorescent analysis of skin samples obtained by punch biopsy (4 mm) from the frontoparietal scalp area of patients with androgenetic alopecia and telogen hair loss. 15 samples obtained from healthy people were used as a reference group.Results.A change in the expression of the VEGF, KGF and TGF-01 growth factors in women with androgenetic alopecia and telogen hair loss was established in comparison with healthy individuals. A correlation was found between the expression of the growth factors under study, age (p ≤ 0.05), as well as the character and duration of the disease (p ≤ 0.05) in women with non-scarring alopecia. The expression of the growth factors is found to be dependent on the clinical form of alopecia (p < 0.001).Conclusion.The VEGF growth factor is established to have the most significant effect on the development of androgenetic alopecia in women, with the KGF, TGF-01 and EGF factors being less significant as the predictors of this disorder. The VEGF growth factor is shown to affect telogen hair loss to a greater extent compared to the EGF factor. Our study confirms differences in the pathogenesis of androgenetic alopecia and telogen hair loss in women. The findings suggest that the VEGF and KGF growth factors, as well as TGF-01 inhibitors may be used as potential pharmacological agents for treating patients suffering from androgenetic alopecia and telogen hair loss.

Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Mahira Hamdy El Sayed ◽  
Marwa Yassin Soltan ◽  
Ahmed Sadek ◽  
Mohamed Abo Shabana Hussein Mohamed
Keyword(s):  
Side Effects ◽  
Hair Loss ◽  
Early Onset ◽  
University Hospital ◽  
Androgenetic Alopecia ◽  
Control Group ◽  
Terminal Hair ◽  
Reactive Oxygen Species Scavenger ◽  
Male Pattern

Abstract Background Androgenetic alopecia (AGA), the most common form of hair loss in men, involves the progressive loss of visible pigmented terminal hair on the scalp in response to circulating androgens. AGA is an autosomal disorder which begins in puberty in genetically predisposed individuals. Aim of the Work To study the effectiveness and safety of the reactive oxygen species scavenger Nacetyl-cysteine (NAC) as a single therapy and in combination with the topically applied minoxidil for treatment of the early-onset androgenetic alopecia in men. Patients and Methods The present study included 100 patients with male pattern hair loss whose age ranged from 18 to 30 years old, recruited from dermatology clinics in Ain Shams University Hospital and Kafr El Sheik University Hospital. Results Overall, all treatments could improve significantly some of the trichoscopic parameters as compared to the control group who did not receive any treatment. The number of terminal hair count increased and the vellus hair count decreased in response to either of treatments; minoxidil, NAC, or both as compared to control. These changes were noticed at both the vertex and frontotemporal sites. The treatment was generally tolerable and the side effects encountered did not necessitate stoppage of the treatment course. Conclusion On the basis of the findings of current study we can conclude that, the role of trichoscopy in increasing the accuracy for diagnosing hair disorders as well as to detect response or failure to treatment, N-acetylcysteine (NAC) improved significantly most of the trichoscopic features of AGA and it was was generally tolerable and the side effects encountered did not necessitate stoppage of the treatment course.

scholarly journals Role of Hair Transplantation in Scarring Alopecia—To Do or Not to Do

2021 ◽  
Author(s):  
Sukhbir Singh ◽  
Kumaresan Muthuvel
Keyword(s):  
Early Diagnosis ◽  
Disease Progression ◽  
Hair Loss ◽  
Treatment Process ◽  
Treatment Protocol ◽  
Aggressive Treatment ◽  
Hair Transplantation ◽  
Scarring Alopecia ◽  
Hair Transplant

AbstractAlopecia in the scalp region leads to psychosocial embarrassment for an individual. Alopecia could be due to several reasons, including genetic, hormonal, traumatic and infections. Cicatricial alopecias (CAs) are considered as trichological emergency, since their progression is rapid and always results in permanent hair loss. The pathogenesis, disease progression and prognosis of CA are poorly understood, and the treatment process is still evolving. An early diagnosis must be established, and aggressive treatment protocol should be followed in the management of scarring alopecia. This article presents various aspects of CA and determines whether hair transplant (HT) should be done in this condition.

scholarly journals Is Every Patient of Hair Loss a Candidate for Hair Transplant?—Deciding Surgical Candidacy in Pattern Hair Loss

2021 ◽  
Author(s):  
Robert H. True
Keyword(s):  
Hair Loss ◽  
Body Dysmorphic Disorder ◽  
Young Patients ◽  
Androgenic Alopecia ◽  
Hair Transplantation ◽  
Detailed History ◽  
Hair Transplant ◽  
Female Pattern Hair Loss ◽  
Unrealistic Expectations ◽  
Male Pattern

AbstractPatterned hair loss which includes both male pattern hair loss (MPHL) or androgenic alopecia (AGA) and female pattern hair loss (FPHL) is the most common indication for hair transplant surgery. However, not all such patients are candidates for hair transplants. There are eight conditions that cause patients to not be appropriate candidates. These are: diffuse unpatterned alopecia (DUPA), cicatricial alopecia (CA), patients with unstable hair loss, patients with insufficient hair loss, very young patients, patients with unrealistic expectations, patients with psychologic disorders such as body dysmorphic disorder (BDD) and trichotillomania, and patients who are medically unfit. In addition, there are patients who are poor candidates and who should undergo hair transplantation only if they understand and accept limited results. The key to identifying these patients involves performing careful and detailed history and examination at the time of consultation.

Advances in Hair Transplantation

2019 ◽  
pp. 243-254
Author(s):  
Alfonso Barrera
Keyword(s):  
Hair Transplantation ◽  
Male Pattern Baldness ◽  
Anatomy And Physiology ◽  
The Past ◽  
History Of ◽  
Male Pattern

This chapter presents a brief review of the history of hair transplantation and the anatomy and physiology of hair follicular units. Also presented is a step-by-step description of the author’s preferred technique and pearls learned over the past 25 years to consistently accomplish natural and aesthetically pleasing results. This very labor-intensive procedure requires a team of skillful assistants to be able to do this well and comfortably. The author also describes the details of equipment and instrumentation needed, from surgical blades to the dissection microscopes, and more. The most frequent cases seen in practice include male pattern baldness, female pattern alopecia, and scarring alopecias secondary to previous surgeries (i.e., post rhytidectomy). The restoration of lost sideburns and a temporal hairline will demonstrate some of these examples.

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