scholarly journals Descriptive study on the clinical profile and demography of patients with chronic folliculitis of leg attending a tertiary referral center

2020 ◽  
Vol 2 ◽  
pp. 104-109
Author(s):  
Thalekkara Madhavan Saranya ◽  
Sarita Sasidharanpillai ◽  
Kidangazhiathmana Ajithkumar

Objectives: The objectives are as follows: (1) To document the clinical profile and demography of patients attending a tertiary referral institution with chronic folliculitis of leg and (2) to document the bacteriological profile of pustular lesions of chronic folliculitis. Materials and Methods: After obtaining clearance from institutional research and ethics committees, consecutive patients who attended our tertiary care center with clinically diagnosed chronic folliculitis of the leg from December 1, 2016, to November 30, 2017, were included in this cross-sectional study. The data regarding patient characteristics and clinical profile of disease were collected using a preset pro forma. Pus culture and sensitivity study was carried out in all patients who had pustules at presentation. The association between duration of disease and extent of disease and duration of disease and clinical grading was evaluated by Pearson’s Chi-square analysis. Results: The study population comprised 39 (78%) males and 11 (22%) females with male to female ratio of 3.5:1. Study participants ranged in age from 16 to 67 years. In 15/24 (62.5%) patients who manifested pustules, pus culture isolated pathogenic bacteria, Staphylococcus aureus, sensitive to cloxacillin in 14 (58.3%) and methicillin-resistant S. aureus in one (4.2%). Limitations: A study conducted in a tertiary referral center not reflecting the disease profile in the community was the major limitation. Conclusion: Staphylococcus aureus sensitive to common antibiotics like cloxacillin being the most common pathogen isolated from pustular lesions signifies the need for more prospective studies with a large sample size to evaluate the role of environmental factors and individual’s immune system in maintaining the inflammation in chronic folliculitis of the leg.

2019 ◽  
Vol 10 ◽  
pp. 204062231984790
Author(s):  
Kai-Lung Chen ◽  
Hsien-Yi Chiu ◽  
Jui-Hsiang Lin ◽  
Jian-De Ye ◽  
Yi-Hsuan Cho ◽  
...  

Background: Multiple comorbidities, including rheumatoid arthritis (RA), have been reported to be associated with psoriasis. Objective: This study aimed to determine the prevalence and the clinical features of RA among patients with psoriasis in a tertiary referral center. Methods: Between January 2000 and December 2013, all patients coded with psoriatic disease (ICD-9 CM 696.0 OR ICD-9 CM696.1) and RA (ICD-9 CM 714.0) in a tertiary medical center were enrolled. Results: There were 10,844 patients and 9073 patients with psoriatic disease and RA identified by diagnostic codes, respectively. Among patients with psoriasis, 111 patients had claim-based diagnosis of RA (1.02%). By reviewing medical records and telephone interview or clinic visits, 25 of the 111 patients (0.23%) was identified unequivocally as having concurrent RA. Among them, 17 (68%) were female and 16 (64%) patients developed arthritis prior to the onset of psoriasis with a mean lag of 6.3 years (1–19 years); 8 (32%) had psoriasis skin lesions prior to the onset of arthritis with a mean lag of 6.9 years (3–20 years); 1 (4%) had skin lesions and arthritis in the same time; 17 (68%) patients also fulfilled the CASPAR classification criteria for psoriatic arthritis. The mean age of onset for arthritis was 49.6 years old. Conclusions: The prevalence of RA in psoriasis might be overestimated in some previous studies using claimed database. Patients with concurrent RA and psoriasis showed a comparable age of onset and male to female ratio, but had more axial involvements compared to patients without psoriasis.


2020 ◽  
Vol 6 (1) ◽  
pp. 19-23
Author(s):  
Monwar Tarek ◽  
Latifa Rahman ◽  
Md Manirul Islam ◽  
Nilufa Parvin

Background: Monoclonal gammopathy are haematologic disorder characterized by abnormal production of one or more immunoglobulin clone. Accurate detection and quantitation of monoclonal immunoglobulins is important for diagnosis and management of monoclonal gammopathies.There are very few studies related to monoclonal gammopathy in Bangladesh. This study wasaimed to observe the clinical profile and immunoglobulin pattern of monoclonal gammopathy cases in a tertiary care referral center. Objective: This study wasaimed to observe the clinical profile and immunoglobulin pattern of monoclonal gammopathy cases in a tertiary care referral center. Methodology: This cross sectional study was conducted in the Department of Haematology, Armed Forces Institute of Pathology (AFIP), Dhaka Cantonment, Dhaka. Study Period was July 2014 to Dec 2014. Patients with the age between 40 to 70 yearsof both sexes who were diagnosed as cases of monoclonal gammopathies was selected as study population. All patients were interviewed by using standard questionnaire and general medical condition of the patients was evaluated through history taking, clinical examination and laboratory investigations. Bone marrow microscopic examination, serum protein electrophoresis, immunofixationelectrophoresis (IFE), skeletal survey and relevant biochemical tests including serum creatinine, calcium, albumin and urinary BJP were performed. Protein electrophoresis of the samples was performed by automated capillary electrophoresis machine. Results: A total of 30 cases were recruited for this study. Out of 30 monoclonal gammopathy cases, majority of cases 17(56.7%) were between 60 to 70 years age group. Mean age was 57.13(±9.66) years. Male were predominant 19(63.0%) and Male female ratio was 1.72:1. Among the patients, low backache and pallor was common in majority (80%) of the cases, while fatigue and fever were present in 73.3% and 70.0% cases respectively. Among the patients, 7(23.3%) were hypertensive, 6(20.0%) were diabetic, 3(10.0%) patients were suffering from CKD with hypertension, 3(10.0%) had bronchial asthma, 1(3.3%) was with hypertension and Diabetes Mellitus. Depending on different laboratory findings, among all the 30 cases, 21(70%) cases were diagnosed as multiple myeloma, 5(16.6%) cases were MGUS and 2(6.7%) cases were Smouldering multiple myeloma and kappa light chain multiple myeloma each. Among the multiple myeloma cases, 11(36.6%) cases had IgG Kappa monoclonal gammopathy and 6(20.0%) cases had IgG Lambda monoclonal gammopathy. Conclusion: Monoclonal gammopathy occurs predominantly in male population at around sixth decade and mostly are presented with fatigue and bone pain. Majority of the patients suffered from multiple myeloma. Journal of National Institute of Neurosciences Bangladesh, 2020;6(1): 19-23


2015 ◽  
Vol 02 (04) ◽  
pp. 187-191 ◽  
Author(s):  
Mullai Vasanthan ◽  
Saji James ◽  
S Shuba ◽  
J Abhinayaa ◽  
Elayaraja Sivaprakasam

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