scholarly journals Intrathecal pump catheter-tip granuloma recurrence with associated myelomalacia – How safe is intrathecal analgesic infusion therapy? A case report

2019 ◽  
Vol 10 ◽  
pp. 62 ◽  
Author(s):  
Moritz Haering ◽  
Christian Saleh ◽  
Phillip Jaszczuk ◽  
Markus Koehler ◽  
Margret Hund-Georgiadis

Background: A serious complication of intrathecal (IT) infusion therapy for pain management is catheter-tip-associated granuloma. Catheter-tip granulomas can lead to permanent severe neurological sequelae if not promptly detected. Case Description: We report a patient with a recurrence of a catheter-tip granuloma causing a high-grade paresis of the lower extremities and we review briefly the literature. Conclusion: Patients with IT pump therapy presenting new neurological findings need prompt imaging of the spinal axis to rule out a catheter-tip granuloma. In case of catheter-tip granuloma, early surgical decompression is important.

2020 ◽  
Vol 11 ◽  
pp. 97
Author(s):  
Wilson P. Lao ◽  
Jordan M. Thompson ◽  
Lauran Evans ◽  
Yohanan Kim ◽  
Laura Denham ◽  
...  

Background: The aim of the study was to present a case of mixed olfactory neuroblastoma (ONB) and carcinoma, an extremely rare tumor with only a few cases in the published literature. Case Description: An otherwise healthy 27-year-old male presented with sinus complaints, headache, and unilateral eye discharge. Imaging and endoscopy revealed a mass presumed to represent a juvenile nasopharyngeal angiofibroma. Unexpectedly, the final pathology report revealed high grade mixed ONB and carcinoma. This tumor is the sixth and youngest documented patient with mixed ONB and carcinoma. Conclusion: Physicians should remain vigilant for the possibility of malignancy in their approach to nasal cavity masses, even in young otherwise healthy patients. Careful review of the immunohistopathology should also be taken, as mixed olfactory tumors such as these are aggressive, rare entities that require multidisciplinary oncologic care.


2020 ◽  
Vol 11 ◽  
pp. 417
Author(s):  
Eduardo Augusto Iunes ◽  
Enrico Barletta ◽  
Telmo Augusto Barba Belsuzarri ◽  
Daniel Paz Araujo ◽  
Fabio Sparapani ◽  
...  

Background: Severe ankylosing spondylitis (AS) affects the entire spine, increasing the risk of vertebral fractures. There are several fusion procedures used (e.g., anterior, posterior, or combined 360° procedures) to stabilize these fractures. Case Description: A 45-year-old male with a 33-year diagnosis of AS presented with a progressive quadriparesis of 6 months’ duration. Previously, he had surgery on both hips. The medical report documented degenerative spondylolisthesis at the C5-C6 level along with syndesmophytes a herniated disc and stenosis. Following a circumferential decompression/fusion without complications, the patient’s symptoms resolved. Conclusion: For patients presenting with cervical fractures and AS, circumferential surgical decompression/ fusion may result in good outcomes.


2020 ◽  
Vol 11 ◽  
pp. 279
Author(s):  
Luis Diaz-Aguilar ◽  
Usman Khan ◽  
Ronald Sahyouni ◽  
Nolan James Brown ◽  
Scott Olson ◽  
...  

Background: Pancreatic ductal adenocarcinoma (PDAC) is the most common pancreatic malignancy, which rarely metastasizes to the spine. Case Description: Here, we present a lytic lumbar metastatic PDAC resulting in severe epidural spinal cord compression (ESCC) with instability. The lesion required preoperative particle embolization, surgical decompression, and fusion. Conclusion: This case report shows that PDAC may metastasize to the lumbar spine requiring routine decompression with fusion.


2012 ◽  
Vol 73 (S 02) ◽  
Author(s):  
L. M. Marques ◽  
J. Pimentel ◽  
P. Escada ◽  
G. Neto D'Almeida

Chirurgia ◽  
2019 ◽  
Vol 32 (5) ◽  
Author(s):  
Damiano Bisogni ◽  
Riccardo Naspetti ◽  
Luca Talamucci ◽  
Andrea Valeri ◽  
Roberto Manetti

Author(s):  
Sameer Peer ◽  
Vivek Murumkar ◽  
Karthik Kulanthaivelu ◽  
Chandrajit Prasad ◽  
Shilpa Rao ◽  
...  

Abstract Background Diffuse leptomeningeal glioneuronal tumor (DLGNT) has been recently described in the literature. The complete neuroimaging spectrum and histopathological characteristics of this entity are yet to be elucidated. In an endemic region, diffuse leptomeningeal enhancement on neuroimaging with associated communicating hydrocephalus is usually suggestive of infective meningitis and the patients are started on empirical anti-microbial therapy. However, it is important to consider other differential diagnosis of leptomeningeal enhancement in such cases, particularly if the clinical condition does not improve on anti-microbial therapy. An early diagnosis of a neoplastic etiology may be of particular importance as the treatment regimens vary considerably depending on the underlying disease condition. Case presentation In this case report, we describe a case of DLGNT with high-grade histopathological features which was initially managed as tubercular meningitis based on the initial neuroimaging findings. Due to worsening of the clinical course and subsequent imaging findings at follow-up, a diagnosis of DLGNT was considered and subsequently proven to be DLGNT with features of anaplasia on histopathological examination of leptomeningeal biopsy specimen. Conclusion This case highlights the importance of recognizing certain subtle finding on MRI which may help in an early diagnosis of DLGNT which is crucial for appropriate treatment.


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