scholarly journals Dorsal epidural “Spindle Cell Lipoma” in a pregnant female

2021 ◽  
Vol 12 ◽  
pp. 162
Author(s):  
Valerio di Norcia ◽  
Luigi Valentino Berra ◽  
Luca D’Angelo ◽  
Antonio Santoro
Keyword(s):  
Thoracic Spine ◽  
Tumor Recurrence ◽  
Spindle Cell ◽  
Clinical Course ◽  
Malignant Degeneration ◽  
Spindle Cell Lipoma ◽  
Tumor Excision ◽  
Progressive Paraparesis ◽  
Lipomatous Tumors

Background: Spindle cell lipoma (SCL) constitutes just 1.5% of all lipomatous tumors. They typically occur in the upper back and shoulders. Here, we report a 37-year-old female presenting with a SCL in the dorsal epidural thoracic spine, during her 9th month of pregnancy. Case Description: A 37-year-old female presented with a subacute (2 months) progressive paraparesis during her 9th month of pregnancy. The MR showed a dorsal epidural mass at the D8 level. Following a cesarean section, the patient underwent a laminectomy for tumor excision. Microscopically, the lesion proved to be a SCL. At 5-year follow-up, there was no tumor recurrence. Conclusion: SCL represents a variant of benign lipomas that may occur in the dorsal thoracic spine. Gross total excision may be followed by a benign clinical course without recurrence or malignant degeneration. Very atypical SCLs need closer follow-up to avoid the misdiagnosis of liposarcoma.

Iodine-125 interstitial brachytherapy after tumor excision: an alternative eye-sparing surgery for lacrimal gland carcinoma

2021 ◽  
Author(s):  
Yang-jun Li ◽  
Ping Wang ◽  
Shao-bo Zhang ◽  
Xiao-na Ning ◽  
Chen-jun Guo ◽  
...  
Keyword(s):  
Lacrimal Gland ◽  
Tumor Recurrence ◽  
Tumor Resection ◽  
Interstitial Brachytherapy ◽  
Tumor Excision ◽  
Control Tumor ◽  
Gland Carcinoma ◽  
Iodine 125 ◽  
Good Cosmesis

Abstract Background:To describe the preliminary suppressive effects of iodine 125 brachytherapy for malignant lacrimal gland tumors after excisionMethods:The study recruit 9 patients with lacrimal gland carcinoma from May 2017 to December 2020. All patients underwent eye sparing surgical tumor resection first and then received iodine 125 interstitial brachytherapy to prevent tumor recurrence. We look over whether tumor recurred or metastasized by detecting the visual function and CT/MRI/PET MRI of every patient.Results1 patient was lost visit. The median follow up period was 29 months of other 8 patients (range, 7 43 months). One patient experienced recurrence two years later but was free from local disease after iodine 125 seeds were implanted one more time. The vision of one female patient was lost due to the seeds moving to the optic nerve. In the remaining 6 patients the vision was no changed, and CT/MRI showed no tumor was recurrencedConclusions:Permanent iodine 125 strip implantation in the orbit can be used as an alternative eye sparing surgery for malignant lacrimal gland tumors after tumor excision. It can control tumor recurrence and maintenance of vision and good cosmesis.

Spindle Cell Lipoma of the Foot and the Application of CD34 Immunohistochemistry to Atypical Lipomatous Tumors in Unusual Locations

2000 ◽  
Vol 8 (3) ◽  
pp. 222-227 ◽  
Author(s):  
Cary D. Austin ◽  
Jon R. Tiessen ◽  
Anuradha Gopalan ◽  
Jesse M. Williams ◽  
Charles D. Bangs ◽  
...  
Keyword(s):  
Spindle Cell ◽  
Spindle Cell Lipoma ◽  
Atypical Lipomatous Tumors ◽  
Lipomatous Tumors

Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma With Features Mimicking Spindle Cell Lipoma

2019 ◽  
Vol 28 (3) ◽  
pp. 336-340 ◽  
Author(s):  
Judith A. S. Jebastin ◽  
Kyle D. Perry ◽  
Dhananjay A. Chitale ◽  
Michael P. Mott ◽  
Jessica Sanchez ◽  
...  
Keyword(s):  
Spindle Cell ◽  
Spindle Cell Lipoma ◽  
Rb1 Gene ◽  
Prognostic Features ◽  
Atypical Lipomatous Tumor ◽  
Lipomatous Tumor ◽  
Well Differentiated ◽  
Mdm2 Amplification ◽  
Lipomatous Tumors

Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) and spindle cell lipoma are lipomatous tumors with distinct clinical, molecular, and prognostic features. Although histological and immunophenotypic features can overlap between ALT/WDL and spindle cell lipoma, the oncogenesis and clinical behavior are markedly different. In borderline cases, molecular analysis for MDM2 or CDK4 amplification can aid in distinguishing ALT/WDL from spindle cell lipoma. Although dedifferentiated liposarcoma has been reported to harbor both MDM2 amplification and loss of the RB1 region, we are not aware of a reported RB1 loss in well-differentiated ALT/WDL. In this article, we present a 69-year-old woman with a lipomatous tumor in the gluteal region that histologically, immunohistochemically, and molecularly mimicked spindle cell lipoma (with positive immunohistochemical staining for CD34 and loss of the RB1 gene region), yet harbored amplification of MDM2 and CDK4 confirmed by fluorescence in situ hybridization, supporting classification as ALT/WDL. This case strengthens the argument that in atypical clinical contexts, molecular studies for MDM2/CDK4 should be considered in tumors resembling spindle cell lipoma.

Spindle Cell Lipoma with Ossification Mimicking Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma: A Case Report

2021 ◽  
pp. 106689692110557
Author(s):  
Jiro Ichikawa ◽  
Tomonori Kawasaki ◽  
Hiroki Imada ◽  
Atsushi Enomoto ◽  
Naofumi Taniguchi ◽  
...  
Keyword(s):  
Spindle Cell ◽  
Final Diagnosis ◽  
Positive Staining ◽  
Cyclin Dependent Kinase ◽  
Spindle Cell Lipoma ◽  
Osteoid Tissue ◽  
Well Differentiated ◽  
Atypical Lipomatous Tumors ◽  
Lipomatous Tumors

Although spindle cell lipoma (SCL) is a subtype of lipoma, the characteristics of SCL are observed in both lipomatous and non-lipomatous tumors. In this article, we present a case of SCL with ossification mimicking atypical lipomatous tumors/well-differentiated liposarcomas (ALTs/WDLs). Considering the findings of magnetic resonance imaging and needle biopsy, which exhibited ALTs/WDLs, marginal resection was performed. Histopathological findings demonstrated mature adipocytes and spindle cells without atypia and no malignant osteoid tissue in the ossified region. In addition, immunohistochemistry (IHC) showed positive staining for CD34, heterogeneous retinoblastoma protein deficiency, and negative staining for mouse double minute 2 homolog (MDM2) and cyclin-dependent kinase. Fluorescence in-situ hybridization showed negative amplification of MDM2. The final diagnosis of the tumor was established using IHC as an extremely rare SCL with ossification.

scholarly journals A Painless Restricted Motion of the Thumb: What Etiology? About An Uncommon Tumor in Uncommon Localization

2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Naoufal Elghoul ◽  
Mohammed Benchakroun ◽  
Azzelarab Bennis ◽  
Omar Zaddoug ◽  
Ali Zine ◽  
...  
Keyword(s):  
Spindle Cell ◽  
Excisional Biopsy ◽  
Histopathological Analysis ◽  
Spindle Cell Lipoma ◽  
Lateral Aspect ◽  
Fourth Case ◽  
Uncommon Tumor

Lipomas in fingers are rare and account for less than 1% of all cases. As a type of lipoma, the spindle cell lipoma is exceptional and it presents 1.5% of total adipocyte tumors. Moreover, its localization in the thumb is extremely rare. Only three cases have already been reported in adults; our case constitutes the fourth case, which is about a 61-year-old female who presented since 18 months a mass on the ulnar lateral aspect of the thumb. After clinical and radiological assessments, an entire excisional biopsy of the mass was performed. The histopathological analysis confirmed the spindle cell lipoma of the thumb. At the last follow-up of two years, the patient did well with no recurrence and no restricted motion of the thumb. So, although lipomas of the digit are rare, they should be considered a possible etiology of either painful or mechanic restricted motion of the digit.

scholarly journals Melanotic Neuroectodermal Tumor of Infancy in the Maxilla

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Daniel Falbo Martins de Souza ◽  
Daniel Isaac Sendyk ◽  
Juliana Seo ◽  
Eduardo Vasques da Fonseca ◽  
Maria da Graça Naclério-Homem ◽  
...  
Keyword(s):  
Tumor Recurrence ◽  
Surgical Excision ◽  
Optimal Outcome ◽  
Recurrence Rates ◽  
Anterior Maxilla ◽  
Tumor Excision ◽  
Complete Surgical Excision ◽  
Neuroectodermal Tumors ◽  
One Year

Melanotic neuroectodermal tumors of infancy (MNTIs) are rare fast-growing tumors with high recurrence rates. These tumors, which originate in the neural crest, commonly occur in the anterior maxilla of children under the age of one. Here, we describe an MNTI case in a two-month-old girl with increasing swelling in the left cheek. MNTI was diagnosed in this case following tomography and biopsy. The patient's histological and immunohistochemical profile indicated a remarkable combination of neural, melanocytic, and epithelial cell differentiation. One year following tumor excision, a follow-up examination revealed that the child exhibited no tumor recurrence. Approximately 260 cases of MNTI have been reported since this type of tumor was first described. In the present case, early diagnosis minimized the difficulties and risks associated with treatment and facilitated an optimal outcome. Despite complete surgical excision, careful followup is recommended. In addition, maxillary functional orthopedics and reconstruction may be necessary in cases of MNTI.

scholarly journals Giant Spindle Cell Lipoma of Middle Finger: Case Report and Review of Literature

2021 ◽  
Author(s):  
Rajan T. M. Sheeja ◽  
Thomas Bestin ◽  
D. S. Aabha
Keyword(s):  
Case Report ◽  
Spindle Cell ◽  
Full Range ◽  
Middle Finger ◽  
Heterogeneous Mixture ◽  
Review Of Literature ◽  
Spindle Cell Lipoma ◽  
Giant Lipoma ◽  
Collagenous Stroma ◽  
Lipomatous Tumors

AbstractWe present a case of a giant Spindle cell lipoma of dimensions 11 cm × 7 cm, involving the middle finger of a 62-year-old female, without distal neurovascular deficits. Spindle cell lipoma is a rare subtype that accounts for 1.5% of all lipomatous tumors. They show a heterogeneous mixture of lipomatous tissue with mature adipocytes interspersed with spindle-shaped cells, without atypia in a sclerotic collagenous stroma. Immunohistochemical (IHC) marker CD34 was positive but negative for S100. The entire tumor was removed with recovery of full range of movements. The case is reported due to the unusual location of a rare variant of giant lipoma involving a finger.

Inflammatory Myofibroblastic Tumour in Antimesenteric Border of Descending Colon of Children: A Case Report

2015 ◽  
Vol 3 (1) ◽  
pp. 47-50
Author(s):  
Shahnoor Islam ◽  
AKM Amirul Morshed ◽  
Afiqul Islam
Keyword(s):  
Soft Tissue ◽  
Spindle Cell ◽  
Inflammatory Myofibroblastic Tumour ◽  
Pathological Findings ◽  
Soft Tissue Lesion ◽  
Soft Tissue Tumours ◽  
Inflammatory Pseudotumour ◽  
Erythrocyte Sedimentation ◽  
Antimesenteric Border

Inflammatory myofibroblastic tumour (IMT) occurring at intraabdominal sites in children has rarely been described. Inflammatory pseudotumour is a soft tissue lesion that may be confused with a sarcoma. It is abbreviated as IMT. Inflammatory myofibroblastic tumour, also known as soft tissue tumours, atypical fibromyxoid tumours, pseudosarcomatous fibromyxoid tumour, plasma cell granuloma, pseudosarcomatous myofibrotic proliferation, post-operative spindle cell nodules. In this paper, we describe a case of inflammatory myofibroblastic tumour (IMT) with an unusual constellation of clinical, pathological findings. A 10-year-old girl had an 7-cm intraabdominal mass accompanied by severe anemia, fever, constipation, weight loss, thrombocytosis, elevated erythrocyte sedimentation rate. Laparotomy was performed. The final pathologic diagnosis was IMT. At the most recent follow up (12months) after excision of the tumour, the patient was symptom-free and there was no evidence of tumour recurrence.J. Paediatr. Surg. Bangladesh 3(1): 47-50, 2012 (January)

Spindle Cell Lipoma of the Posterior Axilla: A Case Report

2008 ◽  
Vol 59 (1) ◽  
pp. 45
Author(s):  
Jee Young Lee ◽  
Kyung Jin Suh ◽  
Sang Yoon Kim
Keyword(s):  
Case Report ◽  
Spindle Cell ◽  
Spindle Cell Lipoma
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