scholarly journals Giant posterior mediastinal schwannoma requiring a thoracoabdominal approach for excision: Case report and literature review

2021 ◽  
Vol 12 ◽  
pp. 241
Author(s):  
Anindya Bhowmik ◽  
Sneha Bisht ◽  
Ko Ko Zayar Toe ◽  
K Joshi George
Keyword(s):  
Surgical Excision ◽  
The Body ◽  
Low Back ◽  
Who Grade ◽  
Mediastinal Tumors ◽  
Common Benign Tumor ◽  
Large Size ◽  
Thoracoabdominal Approach ◽  
Posterior Mediastinal

Background: A schwannoma is a tumor of the peripheral nerve sheath. They are the most common benign tumor; presenting at any age, and at any site of the body and also one of the most common posterior mediastinal tumors. Posterior mediastinal schwannoma is usually identified incidentally in chest radiographs and with follow-up imaging such as CT scan. Large posterior mediastinal schwannoma usually presents with local symptoms. To confirm diagnosis and obtain local control, surgical excision is the usual approach. Case Description: Here, we present a case of a 56-year-old female who presented with chronic low back pain. The lesion was picked up on an ultrasound scan to look at her kidneys. She was not experiencing any neurological symptoms. Excision of the tumor was made through a right thoracoabdominal approach. A WHO Grade 1 tumor was diagnosed on histology. There were no signs of recurrence in the follow-up scans. Conclusion: Giant posterior mediastinal schwanommas are very rare with only one other reported case requiring a thoracoabdominal approach for excision. Though giant schwanommas raise concern for malignancy due to their large size, they generally turn out to be benign

scholarly journals Clinical and in Vivo Response Following Surgery or Surgery Plus Adjuvant Chemotherapy or Immunotherapy for Colorectal Carcinoma in a Rat Model

1983 ◽  
Vol 76 (10) ◽  
pp. 833-840 ◽  
Author(s):  
A K House ◽  
M A L Maley
Keyword(s):  
Body Weight ◽  
Adjuvant Chemotherapy ◽  
Surgical Excision ◽  
The Body ◽  
Recurrent Tumour ◽  
Mesenteric Node ◽  
And Control ◽  
Tumour Weight

Two cohorts of rats, 240 with colon cancer and 150 controls, were assessed clinically and immunologically for their response to tumour and its management which was either by surgical excision alone or by surgical excision combined with either adjuvant chemotherapy or immunotherapy. The histology and invasion characteristics were observed for similarity with those of human lesions. Metastases were found in liver, lymph nodes, the peritoneum or lungs in 27% of animals during follow up. Significantly fewer adjuvant-treated rats had metastases than those receiving surgery alone ( P < 0.05), and less total tumour weight was found in the adjuvant-treated rats at four ( P < 0.03) and six ( P < 0.001) weeks postoperatively. Animals in the adjuvant immunotherapy group survived longer than in either other group ( P < 0.001). The crude parameters of host response to tumour, body, spleen and mesenteric lymph node weight were recorded and the latter two indexed to body weight. The body weight of tumour and control rats increased significantly with time ( P < 0.04). The spleen and mesenteric node indices were significantly ( P < 0.04) greater in tumour than control rats and were varied by recurrent tumour growth and by the adjuvant treatment administered postoperatively.

scholarly journals Ectopic intraconal orbital meningioma – A rare case report

2021 ◽  
Vol 12 ◽  
pp. 305
Author(s):  
Anil Kumar Sharma ◽  
Charandeep Singh Gandhoke ◽  
Somen Misra ◽  
Ashik Ravi ◽  
Rakesh Kumar Gupta ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Visual Outcome ◽  
Surgical Excision ◽  
Histopathological Diagnosis ◽  
Who Grade ◽  
Rare Case Report ◽  
History Of ◽  
The Right ◽  
Orbital Meningioma

Background: Ectopic orbital meningiomas (OM) are a rare subset of OMs which are neither attached to the optic nerve sheath nor to the surrounding bone. Case Description: We report the case of a 65-year-old female who presented with a 1 year history of proptosis followed by visual loss and restricted right eye movements since 3 months. Radiology of the orbits was suggestive of intraorbital, intraconal, and heterogeneous contrast enhancing right eye lesion which was completely excised through supraorbital orbitotomy approach. Intraoperatively, the right optic nerve, though compressed, and displaced inferiorly, was free from the lesion. The final histopathological diagnosis was “Meningioma WHO Grade I.” At 3 months follow-up, patient’s vision in the right eye improved from perception of light positive to 6/12 and there was no evidence of recurrence. Conclusion: Rarity of ectopic OM, total surgical excision with an excellent postoperative visual outcome prompted us to report this case.

scholarly journals A Recurrence of a Giant Odontogenic Keratocyst: Radiographic Follow-Up

2018 ◽  
Vol 1 (1) ◽  
pp. 42-46
Author(s):  
Luis Alberto Mendez ◽  
Ricardo Martinez ◽  
David Josue Echavarria ◽  
Raul Antonio Gonzalez
Keyword(s):  
Periodontal Disease ◽  
Clinical Evaluation ◽  
Surgical Excision ◽  
The Body ◽  
Dental School ◽  
Odontogenic Keratocyst ◽  
Imaging Studies ◽  
Central Lesion ◽  
The Third

Odontogenic keratocyst could be a very aggressive lesion which may be imperceptible for the patient, not giving any type of symptomatology. This is usually discovered as a finding during a clinical evaluation of the maxillofacial area. The diagnosis of this lesion is merely histological, although it has some radiographic features that presumptively indicate the diagnosis. During a dental school brigade a patient came referring dental mobility, periodontal disease was absent and oral examination revealed a large swelling identified in the body of the mandible. Imaging studies revealed a large central lesion diagnosed as OKC when biopsy was performed. After enucleation and curettage of the lesion radiographic follow-up was conducted every six months, at the third six month period recurrence of the lesion was present and surgical excision was performed with the recommendation of and strict radiographic follow-up in quarterly periods.

scholarly journals APPLICATION OF KSHARASUTRA OVER SURGICAL EXCISION OF NEUROFIBROMA (NF1): A CASE REPORT

2021 ◽  
Vol 12 (1) ◽  
pp. 31-33
Author(s):  
Sunil Kumar ◽  
Saurabh Jain ◽  
Rashi Sharma
Keyword(s):  
Genetic Disorder ◽  
Surgical Excision ◽  
Neurofibromatosis Type ◽  
The Body ◽  
Consensus Development ◽  
Consensus Development Conference ◽  
Medial Side ◽  
Café Au Lait Spots

Neurofibromatosis type 1 (NF1) or Von Recklinghausen's disease is a rare genetic disorder characterized by the development of multiple noncancerous tumors of nerves and skin (neurofibromas). Head and neck neurofibroma are generally located in the soft tissue. Here, a case of a 42-year-old man with NF1 has been presented. The disease started in childhood with the appearance of multiple hyperpigmented skin macules. He has generalized freckling and café-au-lait spots all over the body and cutaneous nodules with multiple sizes. The diagnosis of NF1 was made according to presence of two or more diagnostic criteria of the National Institute of Health Consensus Development Conference. On the basis of symptoms, it was closely related to the Kaphaja Arbuda. Acharya Sushruta mentioned Kshara and Ksharasutra in Arbuda Chikitsa. So, Ksharasutra was tied on the root of one of the neurofibroma size of 4 x 2.5 cm present on medial side of the mid arm. The Fibroma was shed-off completely after 7 days and no recurrence was observed in a follow up at the end of 12 months after application of Ksharasutra.

scholarly journals Microcystic Serous Cystadenoma of Pancreas Presenting With Chronic Diarrhea

2018 ◽  
Vol 08 (03) ◽  
pp. 045-049
Author(s):  
Shravya Sudesh Kotian ◽  
Shubha P Bhat ◽  
Rajshekhar Mohan ◽  
Sajitha K.
Keyword(s):  
Imaging Techniques ◽  
Surgical Excision ◽  
Serous Cystadenoma ◽  
The Body ◽  
Cystic Neoplasms ◽  
Large Size ◽  
History Of ◽  
Serous Cystic Neoplasms ◽  
Pancreatic Cystic Neoplasms ◽  
Unnecessary Intervention

AbstractPancreatic cystic neoplasms are increasingly being recognized due to widespread use of advanced imaging techniques. The prevalence of pancreatic cystic lesions is estimated to be between 2.6% - 19.6%. Serous Cystic Neoplasms account for nearly 16% of surgically resected th th pancreatic cystic neoplasms. They commonly occur in females between 5 and 6 decade of life. These tumours are essentially benign and asymptomatic unless they attain a large size. Majority of them occur in the body and tail of pancreas. Malignant transformation is reported in 1%-3% of cases. Surgical excision is the treatment of choice. Thus, it is important to accurately diagnose this lesion to avoid unnecessary intervention in the form of chemotherapy or uncalled for surgical resection. We report a rare case of a 65 year old male who presented with a history of intermittent diarrhea.

Tenosynovial Giant Cell Tumor in the Hand: Experience with 173 Cases

2020 ◽  
Vol 25 (02) ◽  
pp. 158-163 ◽  
Author(s):  
Hüseyin Bilgehan Çevik ◽  
Sibel Kayahan ◽  
Engin Eceviz ◽  
Seyit Ali Gümüştaş
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Benign Lesion ◽  
Surgical Excision ◽  
Cell Tumor ◽  
Recurrence Rates ◽  
Tenosynovial Giant Cell Tumor ◽  
Common Benign Tumor ◽  
Localization Zone

Background: Tenosynovial giant cell tumor (TSGCT) is the second most common benign tumor of the hand. Even though it is a benign lesion there is still a high incidence of local recurrence (range, 7%–44%) according to data in published papers. In this study, the clinical and epidemiological features of 173 patients who underwent excision of localized TSGCT, the recurrence rates and possible reasons for recurrence were examined in the light of current literature. Methods: Medical records of 173 patients with TSGCT were reviewed. Data on demographic characteristics as well as clinical and intraoperative findings were collected. Patients were asked about the recurrence of the TSGCT and the QuickDASH scoring was applied at the final clinical evaluation after mean follow-up of 81 months. Results: Females were predominantly involved (73%). Patients aged mean 44 years at the time of surgery. There were 93 tumors in flexor zones and 80 tumors in extensor zones of the hand. Of the tumors with flexor zone localization, zone II was most predominantly involved with 46 tumors, and 18 of these were on the index finger. The extensor zones III and IV were mostly involved with 9 tumors each on the middle and ring fingers. A total of 12 recurrences (6.9 %) were determined over the mean follow-up period of 81 months. Conclusions: The characteristics of our patients identified were similar to the previous studies. Surgical excision provides good outcomes in the treatment of TSGCT especially when clear margins are obtained.

scholarly journals Solid pseudopapillary tumor of the pancreas: clinical-pathological features and management of 13 cases

2017 ◽  
Vol 90 (2) ◽  
pp. 171-178 ◽  
Author(s):  
Ovidiu Vasile Bochis ◽  
Madalina Bota ◽  
Emilia Mihut ◽  
Rares Buiga ◽  
Dan Samoila Hazbei ◽  
...  
Keyword(s):  
Pathological Condition ◽  
Demographic Data ◽  
Surgical Excision ◽  
The Body ◽  
Pancreatic Tumors ◽  
Solid Pseudopapillary Tumor ◽  
Young Females ◽  
Complete Surgical Excision ◽  
The Mean

Background and aim. Solid pseudopapillary tumor (SPT) of the pancreas is a rare pathological condition, representing less than 3% of all exocrine pancreatic tumors. SPT usually occurs in young females, without notable symptoms, with a low malignant potential and excellent prognosis.Method. We conducted a retrospective study during the period January 2005 - January 2015. SPT patients admitted in our institution were reviewed by describing demographic data, clinico-pathologic and radiological features, therapeutic management and prognosis records.Results. Thirteen patients with SPT were identified (10 females), with a median age of 30 years. The main clinical presentation was abdominal pain (92.3%). The tumor was mostly located in the body or tail of the pancreas (77%), and the mean size was 8.2 cm. Regarding the surgical approach there were 5 distal pancreatectomies with splenectomy, 3 body and tail pancreatectomies, 2 body and tail pancreatectomies with splenectomy, 2 pancreato-duodenectomy, 1 partial enucleation and of all only 2 partial resections. Postoperative hematoxylin- eosin staining and immunohistochemistry confirmed the diagnosis in all cases. None of the patients had lymph nodes metastases. Only one local invasion. There was one case of death due to postoperative complications. Four cases followed adjuvant systemic chemotherapy. The mean follow-up was 18 months, without evidence of recurrence during this period.Conclusion. SPT should always be considered in the differential diagnosis in young women with a pancreatic tumor. Complete surgical excision is the treatment of choice, and is usually curative. The decision to administer systemic therapy must be individualized. Malignant behavior and late recurrences mandates long-term follow-up for patients with SPT.

scholarly journals Thoracoscopic Surgery for Posterior Mediastinal Mass: Our Initial Experience

2019 ◽  
Vol 15 (2) ◽  
pp. 75-79
Author(s):  
Ranjan Sapkota ◽  
Prakash Sayami
Keyword(s):  
Mediastinal Mass ◽  
Thoracoscopic Surgery ◽  
Surgical Techniques ◽  
Tumor Diameter ◽  
Initial Experience ◽  
Mediastinal Tumors ◽  
Benign Schwannoma ◽  
Posterior Mediastinal ◽  
The Mean

Background: Thoracoscopic surgery has been increasingly used for a variety of indications. Posterior mediastinal tumors form an important component of a thoracic surgeon’s workload. This report represents a summary of our initial experience in thoracoscopic management of such tumors. Methods: We retrospectively reviewed the clinical and operative data from records over the study period. We also describe our usual perioperative management and surgical techniques. Results: A total of 11 patients, 8 being females, were operated during the period of 30 months. Seven were incidental findings, and chest pain was the commonest presentation in symptomatic patients. The mean age of the patients was 38.7 years; mean tumor diameter was 4.4 cm; eight had benign schwannoma, and no patient had a malignant tumor. Mean operative duration was 175.5 min; there were no conversions and no transfusion was required. Mean length of stay in the hospital was 5.6 days. There were no perioperative deaths or major complications. Three minor complications were recorded. Follow-up (4 to 18 months) was uneventful. Conclusions: Thoracoscopic management of posterior mediastinal tumors is feasible and safe.

Forniceal glioma in children

2009 ◽  
Vol 4 (3) ◽  
pp. 249-253 ◽  
Author(s):  
Thomas Blauwblomme ◽  
Pascale Varlet ◽  
John R. Goodden ◽  
Marie Laure Cuny ◽  
Helene Piana ◽  
...  
Keyword(s):  
Residual Disease ◽  
Surgical Excision ◽  
Pediatric Brain Tumors ◽  
Additional Treatment ◽  
High Rate ◽  
Low Grade ◽  
Who Grade ◽  
Retrograde Memory ◽  
Grade Ii

Object Five to ten percent of pediatric brain tumors are located in the ventricles. Among them, forniceal lesions are rare and their management has not often been described. The aim of this study was to review the clinical, radiological, and histopathological features as well as the feasibility of surgical excision and the outcomes in these patients. Methods From a retrospective analysis of 250 cases of supratentorial pediatric glioma, the records of 8 children presenting with forniceal lesions were selected and reviewed. Results The median age of patients in the cohort was 13.5 years. Presenting features included intracranial hypertension (7 cases), hypothalamic dysfunction (2), and memory dysfunction (3). Complete resection was possible in only 1 case, where the lesion was mainly exophytic; the remaining patients had either a partial resection or biopsy. On histological review, the tumors were confirmed as pilocytic astrocytoma (4 lesions), WHO Grade II astrocytoma (3), and ganglioglioma (1). Postoperatively, working and retrograde memory was normal for all patients, but the authors found a mild alteration in verbal episodic memory in 5 patients. Despite fatigability for 5 patients, academic achievement was normal for all but 2, both of whom had preoperative school difficulties. Additional treatment was required for 5 patients for tumor progression, with a median interval of 19 months from surgery. At a median follow-up duration of 4.9 years, all patients had stable disease. Conclusions In this series, forniceal gliomas were found to be low-grade gliomas. They are surgically challenging, and only exophytic lesions may be cured surgically. Due to the high rate of progression of residual disease, adjuvant therapy is recommended for infiltrative tumors, and it yielded excellent results.

scholarly journals Multisystemic Benign Metastasizing Leiomyoma: An Unusual Condition with an Atypical Clinical Presentation

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Fernando Matos ◽  
Cristina Santiago ◽  
Duarte Silva
Keyword(s):  
The Body ◽  
Reproductive Age ◽  
Low Back ◽  
Soft Tissue Density ◽  
Benign Metastasizing Leiomyoma ◽  
Essential Condition ◽  
Atypical Clinical Presentation ◽  
History Of ◽  
Metastasizing Leiomyoma

Benign metastasizing leiomyoma (BML) is a rarely found entity with few documented cases in the literature, usually occurring in women of reproductive age with a history of myomectomy or hysterectomy. The leiomyomas can metastasize to several organs, the lungs being the most commonly affected. We report a case of a 40-year-old female patient who presented at our institution with low back pain. She underwent a lumbar MR that revealed the presence of an expansive and compressive mass in the body of L4. This mass was biopsied, corresponding to a metastasizing leiomyoma with no malignant characteristics. Subsequently, a CT examination showed several soft tissue density round masses in both lungs, but the most striking feature was a 12 cm mass located in the left iliac crest. There was asymmetrical uterus enlargement, caused by the presence of several leiomyomas. Since the lesions were estrogen and progesterone positive, hormone suppression consisting of oophorectomy followed by anastrozole was the chosen treatment. No signs of progression were observed at the 6-month follow-up. This case is one of the very few that occurred in a woman with no previous uterine intervention, adding further evidence that surgery is not an essential condition for this entity to develop.

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