BACTERIAL OTITIS MEDIA IN SLOVAKIA BEFORE AND AFTER PAEDIATRIC UNIVERSAL PNEUMOCOCCAL VACCINATION

Author(s):  
matus macaj
2008 ◽  
Vol 36 (6) ◽  
pp. 1255-1260 ◽  
Author(s):  
F Ansaldi ◽  
L Sticchi ◽  
P Durando ◽  
R Carloni ◽  
P Oreste ◽  
...  

The effect of the pneumococcal conjugate vaccine immunization programme on pneumococcal-associated or potentially pneumococcal-associated hospital admissions in the Italian region of Liguria was assessed. Hospital admission rates were compared in subjects belonging to birth cohorts before and after the introduction of widespread immunization for 0 − 2-year old children with a seven-valent conjugate vaccine (PCV7). Significant reductions in hospitalization rates for all-cause and pneumococcal pneumonia and for acute otitis media were observed in subjects born after widespread uptake of the vaccine. The preventive fraction (a measure of vaccine effectiveness) ranged from 15.2% for all-cause pneumonia to 70.5% for pneumococcal pneumonia. This study contributes to the growing body of information that supports the beneficial effect of PCV7 vaccination.


1993 ◽  
Vol 109 (1) ◽  
pp. 77-82 ◽  
Author(s):  
David O. Merifield ◽  
Nancy J. Parker ◽  
Nannette C. Nicholson

The use of potentially ototoxic topical drugs is controversial. Few experimental reports of audiometric data from human subjects exist. The purpose of this study is to determine if a significant difference between bone conduction hearing sensitivity before and after otic drop treatment for children with chronic suppurative otitis media and patent ventilation tubes exists. A statistical analysis of sensorineural threshold status after treatment of chronic suppurative otitis media with otic drops is presented.


2021 ◽  
Author(s):  
Dina Muktiarti ◽  
Miftahuddin Majid Khoeri ◽  
Wisnu Tafroji ◽  
Lia Waslia ◽  
Dodi Safari

The aim of this prospective study was to investigate the serotypes and antibiotic susceptibility of S. pneumoniae carried by children infected with HIV before and after vaccination with the seven-valent pneumococcal conjugate vaccine in Jakarta, Indonesia in 2013. We collected nasopharyngeal swab specimens from 52 children pre-vaccination and 6 months post-vaccination. Serotyping was performed by conventional multiplex polymerase chain reaction and Quellung reaction. The antibiotic susceptibility profile was obtained by disc diffusion. We determined that 27 (52%) and 24 (46%) of the 52 children carried S. pneumoniae during pre- and post-vaccination periods, respectively with the majority of the isolates being non-vaccine type strains (85% pre-vaccination and 75% post-vaccination). Serotypes 34, 6C, and 16F (two strains each) were the most commonly identified serotypes at pre-vaccination. Serotypes 23A (three strains) and 19F (two strains) were the most commonly identified serotypes post-vaccination. In general, isolates were most commonly susceptible to chloramphenicol (88%) and clindamycin (88%), followed by erythromycin (84%), trimethoprim-sulphamethoxazole (69%), tetracycline (61%), and penicillin (59%). In conclusion, serotypes of S. pneumoniae isolated from the nasopharynges of children infected with HIV varied and were more likely to be non-vaccine type strains both before and after vaccination.


Author(s):  
A. G. Khrykova

Background. The prevalence of allergic rhinitis, which is an intermittent or permanent inflammation of the nasal mucosa caused by exposure to allergens, reaches 35%, according to different authors. Currently, this pathology is often complicated by exudative otitis media, especially in young children. Aim: to develop and justify the feasibility of using laser phoresis of sodium deoxyribonucleate for the treatment of exudative otitis media in children with allergic rhinitis. Methods. A clinical examination, a clinical blood test, rhinoscopy and otoscopy, as well as rhinocytogram, tympanometry (impedance audiometer Heinemann Titan) were performed. In diagnostics of allergic rhinitis, methods of a multifaceted otorhinolaryngological and allergological examination of the patient were used, as well as immunological tests (determination of the level of IgE and allergen-specific antibodies in the blood serum), and skin allergological tests. The examination was conducted before and after the course of treatment, as well as after 6 and 12 months. Results. With drug laser phoresis of sodium deoxyribonucleate administered endonasally and endourally, a stable result was obtained in restoring the drainage functions of the pharyngotympanic tube and reducing the symptoms of allergic rhinitis in preschool children and primary school children. Hearing is objectively improved in patients, and the conductive component is stopped, there is no fluid in the middle ear, sleep improves, the sense of smell is restored, physical performance increases, and childrens fatigue decreases in doing sports. A comparative analysis of the effectiveness of treatment in two groups showed the best results in the group of children receiving laser therapy using sodium desoxyribonucleate from medicinal non-woven textiles for up to 1 year. Repeated treatment with exacerbation of exudative otitis media was necessary to 40% of children in the control group, 12% of children after a course of laser therapy, and only one patient after a course of laser phoresis of sodium deoxyribonucleate. Conclusion. The use of laser radiation reduces the manifestations of the inflammatory process, and the allergic component.


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