Medication compliance and neurological side-effects of neuroleptics in aged patients with schizophrenia

Background: Anal fissure is one of the most common anorectal problem and presents as a tear in the anoderm distal to the dentate line. It is a common proctologic problem and accounts for 10-15% of proctological consultations and seen frequently in young and middle-aged patients. Presently wide range of medical and surgical treatment options were available. Present study was aimed to evaluate the therapeutic efficacy of 5% lignocaine ointment and a combination of 0.2% glyceryl trinitrate and 5% lignocaine in management of acute fissure in ano.Methods: In the present study, a total of 100 patients diagnosed with acute fissure in ano were randomly allocated into two groups (I, II) of 50 patients each and were managed by local application of 5% Lignocaine (LIG) ointment and a combination of both 0.2% Glyceryl trinitrate (NTG) and 5% Lignocaine (LIG) ointment respectively.Results: In the present study, the incidence of anal fissure was higher in males than in females with mean age of occurrence of 35.12 years. Pain was the most common symptom to present with. After six weeks, complete pain relief was seen in most of the patients and was comparable in both the groups but healing was superior in group II when compared to group I. Headache and dizziness were the side effects only noticed in group II.Conclusions: To conclude the study, we can say that the treatment of anal fissure is becoming increasingly medical as it can be carried out on outpatient basis and is cost effective and there is no loss of man hours. Lignocaine may be preferred as the first line treatment as there are no side effects and if there is failure to heal then we can prescribe the combination of both drugs owing to their risk benefit ratio.

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Medication compliance

10.1093/med/9780198754237.003.0011 ◽

2017 ◽

Author(s):

Tom Burns ◽

Mike Firn

Keyword(s):

Side Effects ◽

Motivational Interviewing ◽

Therapeutic Relationship ◽

Medication Compliance ◽

Clinical Interview ◽

Outreach Worker ◽

Careful Monitoring ◽

Improve Compliance ◽

Depot Preparations

Differing terms are used for compliance, including concordance and adherence. This chapter examines the range of obstacles to compliance, including side effects, lack of insight, lack of effectiveness, and resistance to being reminded of the illness. The influence of family and friends is also considered. We believe it is often best to avoid complex explanations, and just accept that it is difficult to remember to take medicines regularly for months and years. Several strategies exist to improve compliance, including depot preparations, psycho-education, and efforts to strengthen the therapeutic relationship. Compliance therapy, based on motivational interviewing, is described in detail. The outreach worker is also uniquely able to rely on prompting and support as well as careful monitoring and structuring the clinical interview to ensure that compliance is regularly assessed. Supporting compliance is a long-term commitment, not a once-off intervention.

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CHRONIC HELICOBACTER PYLORI GASTRITIS: THE ERADICATION EFFICACY&NBSP;OF THE&NBSP;BISMUTH-CONTAINING QUADRUPLE REGIMEN (EBMT)

Journal of Medicine and Pharmacy ◽

10.34071/jmp.2016.2.21 ◽

2016 ◽

pp. 149-158

Author(s):

Ngoc Quy Hue Dang ◽

Van Huy Tran ◽

Thanh Hai Nguyen

Keyword(s):

Helicobacter Pylori ◽

Side Effects ◽

Chronic Gastritis ◽

Medication Compliance ◽

Compliance Rate ◽

Eradication Therapy ◽

Rapid Urease Test ◽

Urease Test ◽

H Pylori ◽

Helicobacter Pylori Gastritis

Background: there has not been yet any research on the effectiveness of H. pylori eradication of bismuth-containing quadruple regimen on chronic gastritis patients in our country. Objective: to evaluate H. pylori eradication rate of bismuth-containing quadruple regimen according to intention to treat (ITT), per protocol (PP) analysis, the rate of side effects and medication compliance. Subjects and Methods: from March 2014 to January 2016 we used bismuth-containing quadruple regimen (EBMT) 10 days for H. pylori eradication therapy for 166 chronic gastritis patients diagnosed based on clinical, endoscopic, rapid urease test, histology and culture. Patients were evaluated side effects and medication compliance at the end of treatment (day 11-14). To assess the eradication, repeating endoscopy with both rapid urease test and histological examination were performed at 4 to 8 weeks after stopping treatment course. Results: H. pylori eradication rates on ITT and PP analysis overall, for naïve patients, after one and more two eradication failures were respectively: 80.72-89.33%, 79.51-90.65%, 91.67-91.67% and 75.00-78.95%. Medication adherence rate was 96.99%. The rates of patients experiencing moderate, severe and very severe side effects were: 19.88%, 0.60% and 1.81%. Conclusion: the EBMT 10-day regimen attained high eradication rates in chronic gastritis patients with rare serious side effects and the high compliance rate. We should apply bismuth-containing quadruple regimen in H. pylori eradication therapy for naïve patients or after one eradication failure. Key words: bismuth-containing quadruple regimen, EBMT, eradication, chronic Helicobacter pylori gastritis

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Stimulant medication in ADHD: what do children and their parents say?

Irish Journal of Psychological Medicine ◽

10.1017/s0790966700008715 ◽

2005 ◽

Vol 22 (1) ◽

pp. 5-9 ◽

Cited By ~ 5

Author(s):

Catherine McElearney ◽

Carol Fitzpatrick ◽

Niamh Farrell ◽

Mary King ◽

Bryan Lynch

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Side Effects ◽

Attention Deficit ◽

Stimulant Medication ◽

Medication Compliance ◽

Structured Interview ◽

Hyperactivity Disorder ◽

Study Population ◽

Children’S Views

AbstractObjectives: The prescription of stimulant medication to children with attention deficit hyperactivity disorder remains topical. Few reports target children's views about taking long-term medication. The aim was to assess child and parent views of stimulant medication. To compare attitudes to medication between two groups of children, those with attention deficit hyperactivity disorder taking stimulant medication and those with epilepsy taking anti-epileptic medication.Method: Forty children (n = 40) with attention deficit hyperactivity disorder on stimulant medication, and 40 children (n = 40) with epilepsy on anti-epileptic medication formed the study population. A semi-structured interview was carried out with each child and parent. Each parent completed the Dosage and Side-effects Questionnaire and the Attitude to Medication Questionnaire. Each child completed the Attitude to Medication Questionnaire.Results: Sixty per cent of children (n = 24) with attention deficit hyperactivity disorder and 62.5% (n = 25) of those with epilepsy knew the name and purpose of their medication. Forty per cent (n = 16) of children in the stimulant group and 32.5% (n = 13) in the anti-epileptic group reported themselves as being non-compliant with medication. In both groups children reported positive aspects to taking medication. More children with epilepsy reported negative aspects. Only 32.5% (n = 13) of children with attention deficit hyperactivity disorder said that they would tell a friend about their medication, while 55% (n = 22) of the children with epilepsy indicated that they would do so. In both groups parents were better informed than their children were about the purpose of the medication. Parents of children with attention deficit hyperactivity disorder tended to be more positive about medication than their children and than the parents in the comparison group.Conclusions: The majority of children and their parents express positive views about the stimulant medication. Children's views about medication compliance and side-effects should be sought, as they may differ significantly from those of their parents. Where parents have noticed positive changes, but children have not, this information can be used therapeutically to help children feel more in control of their behaviour.

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Fewer symptoms vs. more side-effects in schizophrenia? Opposing pathways between antipsychotic medication compliance and quality of life

Schizophrenia Research ◽

10.1016/j.schres.2009.05.022 ◽

2009 ◽

Vol 113 (1) ◽

pp. 27-33 ◽

Cited By ~ 32

Author(s):

A.B.P. Staring ◽

C.L. Mulder ◽

H.J. Duivenvoorden ◽

L. De Haan ◽

M. Van der Gaag

Keyword(s):

Quality Of Life ◽

Side Effects ◽

Antipsychotic Medication ◽

Medication Compliance

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COMPARISON OF DIFFERENT METHOD OF ANALGESIA IN AGED PATIENTSWITH CHRONIC LOW BACK PAIN

HERALD of North-Western State Medical University named after I I Mechnikov ◽

10.17816/mechnikov20179439-45 ◽

2017 ◽

Vol 9 (4) ◽

pp. 39-45

Author(s):

G N Vasilieva ◽

A L Linkov ◽

N O Kukushkina ◽

F I Dimitrienko ◽

A E Karelov

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Side Effects ◽

Prospective Study ◽

Pain Intensity ◽

Chronic Low Back Pain ◽

Low Back ◽

Aged Patients ◽

Nonopioid Analgesic ◽

Equal Effectiveness

Effectiveness of different methods of analgesia was studied in 34 aged patients suffering chronic low back pain. All patients were at age 60 to 86 and were randomized into N-group in which nefopam (60 mg rectally) was administrated and K-group that included patients who received ketoprofen (100 mg rectally). The end-points of this prospective study were decrease of pain intensity after analgesics administration, contentment of therapy, and characteristics of side effects of medications taking (twice daily for three days). We found that pain intensity decreases by 6,3±1,6 in N-group and 6,1±1,3 in K- group (p<0.05 in the both cases) and achieves 0,9±1,4 and 0,9±1,6 in N- and in K-group, respectively (p>0.05 in comparison between groups). No significant differences between groups were in estimation of therapy contentment. No side effects were registered. Thus, our data proved the equal effectiveness of central nonopioid analgesic nefopam and nonselective cyclooxygenise inhibitor ketoprofen for achievement of good analgesia in aged patients with chronic low back pain.

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Localised Gingival Overgrowth in Patient taking Amlodipine

Journal of Nepalese Society of Periodontology and Oral Implantology ◽

10.3126/jnspoi.v4i2.34315 ◽

2020 ◽

Vol 4 (2) ◽

pp. 96-99

Author(s):

Arjun Hari Rijal ◽

Bhageshwar Dhami ◽

Nashib Pandey ◽

Deepa Aryal ◽

Kamana Neupane

Keyword(s):

Side Effects ◽

Male Patient ◽

Treatment Modalities ◽

Third Generation ◽

Middle Aged ◽

Drug Induced ◽

Aged Patients ◽

Gingival Overgrowth ◽

Drug Substitution ◽

Gingival Enlargement

Gingival enlargement is an increase in the size of gingiva. It is one of the side effects of systemic administration of antihypertensives, anticonvulsants, and immunosuppressants. Amlodipine, a new third-generation dihydropyridine, very useful in middle-aged to older aged patients for various cardiovascular conditions can cause gingival enlargement. Treatment modalities for drug induced gingival enlargement include removal of local irritating factors, meticulous plaque removal and drug substitution after consultation with a physician. This article reports an amlodipine induced gingival enlargement and its treatment in a 40 years old hypertensive male patient.

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Effect of Wechat platform on medication compliance of young and middle-aged patients discharged from hospital after PCI

Minerva Surgery ◽

10.23736/s2724-5691.21.09203-0 ◽

2021 ◽

Author(s):

Huijie ZHANG ◽

Xiaoning LU ◽

Tixin GU ◽

Di ZHANG ◽

Jie ZHANG ◽

...

Keyword(s):

Medication Compliance ◽

Middle Aged ◽

Aged Patients

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