A Rational Formulation Design Approach for Dermal Delivery of Retinyl Palmitate

2016 ◽  
Author(s):  
Avnish Patel
Keyword(s):  
Retinyl Palmitate ◽  
Design Approach ◽  
Formulation Design ◽  
Dermal Delivery

Efficient dermal delivery of retinyl palmitate: Progressive polarimetry and Raman spectroscopy to evaluate the structure and efficacy

2015 ◽  
Vol 78 ◽  
pp. 111-120 ◽  
Author(s):  
Jun Bae Lee ◽  
Dong Ryeol Lee ◽  
Nak Cho Choi ◽  
Jihui Jang ◽  
Chun Ho Park ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Retinyl Palmitate ◽  
Dermal Delivery

Formulation design of microemulsion for dermal delivery of penciclovir

2008 ◽  
Vol 360 (1-2) ◽  
pp. 184-190 ◽  
Author(s):  
Weiwei Zhu ◽  
Aihua Yu ◽  
Weihong Wang ◽  
Ruiqian Dong ◽  
Jun Wu ◽  
...  
Keyword(s):  
Formulation Design ◽  
Dermal Delivery

Drug solubility in fatty acids as a formulation design approach for lipid-based formulations: a technical note

2018 ◽  
Vol 44 (9) ◽  
pp. 1551-1556 ◽  
Author(s):  
Yung-Chi Lee ◽  
Chad Dalton ◽  
Brian Regler ◽  
David Harris
Keyword(s):  
Fatty Acids ◽  
Technical Note ◽  
Design Approach ◽  
Drug Solubility ◽  
Formulation Design

Towards a Tangible Philosophy through Design

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Jelle VAN DIJK ◽  
Jonne VAN BELLE ◽  
Wouter EGGINK
Keyword(s):  
Digital Age ◽  
Promising Method ◽  
Design Approach ◽  
The World ◽  
First Results

The combined philosophy and design approach called Philosophy-through-Design (PtD) is proposed using an exemplary project about being-in-the-world in the digital age. PtD is a practical way to do philosophy through designing interventions, and involves various people in the exploration of philosophical concepts. It stems from the overlapping questions found in philosophy and design regarding human-technology interaction. By intertwining both, they benefit from describing, understanding and proposing human-technology interactions to unfold new questions and perspectives. In the exemplary project, being-in-the-world refers to a way of being that is embodied, active, open-ended and situational, based on the phenomenological and embodied theories of Tim Ingold. This concept questions what it means to be human in the digital age and how our lives with technology are built. The first results show the process of weaving together observation, creation and reflection, which presents Philosophy-through-Design as a promising method for designers to practice a tangible philosophy.

Formulation, Design and Development of Niosome Based Topical Gel for Skin Cancer

2017 ◽  
Vol 2 (3) ◽  
Keyword(s):  
Skin Cancer ◽  
Drug Release ◽  
Hemorrhagic Cystitis ◽  
The Body ◽  
Cancer Drug ◽  
Inversion Method ◽  
Body Parts ◽  
Basal Cells ◽  
Formulation Design ◽  
Topical Gel

Melanoma is the most dangerous type of skin cancer in which mostly damaged unpaired DNA starts mutating abnormally and staged an unprecedented proliferation of epithelial skin to form a malignant tumor. In epidemics of skin, pigment-forming melanocytes of basal cells start depleting and form uneven black or brown moles. Melanoma can further spread all over the body parts and could become hard to detect. In USA Melanoma kills an estimated 10,130 people annually. This challenge can be succumbed by using the certain anti-cancer drug. In this study design, cyclophosphamide were used as a model drug. But it has own limitation like mild to moderate use may cause severe cytopenia, hemorrhagic cystitis, neutropenia, alopecia and GI disturbance. This is a promising challenge, which is caused due to the increasing in plasma drug concentration above therapeutic level and due to no rate limiting steps involved in formulation design. In this study, we tried to modify drug release up to threefold and extended the release of drug by preparing and designing niosome based topical gel. In the presence of Dichloromethane, Span60 and cholesterol, the initial niosomes were prepared using vacuum evaporator. The optimum percentage drug entrapment efficacy, zeta potential, particle size was found to be 72.16%, 6.19mV, 1.67µm.Prepared niosomes were further characterized using TEM analyzer. The optimum batch of niosomes was selected and incorporated into topical gel preparation. Cold inversion method and Poloxamer -188 and HPMC as core polymers, were used to prepare cyclophosphamide niosome based topical gel. The formula was designed using Design expert 7.0.0 software and Box-Behnken Design model was selected. Almost all the evaluation parameters were studied and reported. The MTT shows good % cell growth inhibition by prepared niosome based gel against of A375 cell line. The drug release was extended up to 20th hours. Further as per ICH Q1A (R2), guideline 6 month stability studies were performed. The results were satisfactory and indicating a good formulation approach design was achieved for Melanoma treatment.

Design of Prestressed Flexural Sections by the Unified Design Approach

PCI Journal ◽  
1999 ◽  
Vol 44 (5) ◽  
pp. 72-81 ◽  
Author(s):  
Javeed A. Munshi
Keyword(s):  
Design Approach ◽  
Unified Design

Rancangan Lowongan Kerja Online Menggunakan Metode User Centered Design (Studi Kasus: Business Placement Center STMIK AMIKOM Yogyakarta)

2016 ◽  
Vol 3 (1) ◽  
pp. 62
Author(s):  
Rhomita Sari ◽  
Ema Utami ◽  
Armadyah Amborowati
Keyword(s):  
Research Methodology ◽  
Design Approach ◽  
User Centered Design ◽  
Analysis And Design ◽  
Job Vacancy ◽  
Placement Center ◽  
User Centered

Business Placement Center membantu mengelola website alumni dalam memenuhi kebutuhan alumni salah satunya memberikan informasi mengenai lowongan pekerjaan. Website Alumni Amikom sudah memberikan informasi mengenai lowongan pekerjaan. Namun website alumni masih perlu ditambahkan fitur-fitur menu penunjang dalam mempermudah pencarian informasi pekerjaan yang sesuai keinginan pengguna. Penggunaan metode User Centered Design untuk mempermudah pengguna dalam menggunakan fasilitas yang ada pada website ketika mencari informasi lowongan pekerjaan dan pengguna berperan penting dalam setiap proses UCD. Dengan pendekatan User Centered Design diharapkan dapat menghasilkan tampilan dan fungsionalitas yang maksimal pada rancangan sistem yang dibangun sehingga sesuai dengan kebutuhan pengguna. Metode penelitian yang dilakukan yaitu observasi, wawancara dan kuesioner untuk mengetahui kebutuhan pengguna. Analisis dan perancangan menggunakan pendekatan User Centered Design dan implementasi perancangan sistem. Hasil penelitiannya adalah pengguna merasa nyaman dengan tampilan antarmuka website yang sudah dibangun, informasi yang disajikan mudah dipahami dan fitur-fitur menu sudah berhasil berjalansesuai fungsi.Business Placement Center help manage the website for the needs of alumnus one of them is to provide information on a vacancy. The alumnus website’s provides information about job vacancy. The website still need the support to facilitate the searching all the features the work in accordance with what the use. The method of user centered design to make it easy for users in the use of the existing facilities at the website while searching for information a vacancy and users play an important role in any proses UCD. User Centered Design approach is expected to produce the interface and functionality maximal built in the system so that in accordance with the need of users. Research methodology was by observation, interviews and quesionnaires to find out the need of users. Analysis and design using UCD approach and implementation of the system. The results of research is users feel comfortable with a display interface of website which have been built, the information is easily understood and menu features has been successfully run a function.

Sign in / Sign up

Export Citation Format

Share Document