2 / The oncofoetal protein IMP3 can predict aggressive behaviour and poor clinical outcome in neuroendocrine tumours

2018 ◽  
Author(s):  
Larisa Gurevich ◽  
Mariya Byakhova
Keyword(s):  
Clinical Outcome ◽  
Aggressive Behaviour ◽  
Neuroendocrine Tumours ◽  
Poor Clinical Outcome

High expression level of geminin predicts a poor clinical outcome in salivary gland carcinomas

2010 ◽  
Vol 56 (7) ◽  
pp. 883-892 ◽  
Author(s):  
Manabu Yamazaki ◽  
Satoshi Fujii ◽  
Yukinori Murata ◽  
Ryuichi Hayashi ◽  
Atsushi Ochiai
Keyword(s):  
Salivary Gland ◽  
Clinical Outcome ◽  
High Expression ◽  
Expression Level ◽  
Poor Clinical Outcome ◽  
Salivary Gland Carcinomas ◽  
High Expression Level

PARK2andPACRGare commonly downregulated in clear-cell renal cell carcinoma and are associated with aggressive disease and poor clinical outcome

2012 ◽  
Vol 52 (3) ◽  
pp. 265-273 ◽  
Author(s):  
Marieta I. Toma ◽  
Daniela Wuttig ◽  
Sandy Kaiser ◽  
Alexander Herr ◽  
Thomas Weber ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Clinical Outcome ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Clear Cell ◽  
Poor Clinical Outcome ◽  
Cell Renal Cell Carcinoma ◽  
Aggressive Disease

The elevated preoperative derived neutrophil-to-lymphocyte ratio predicts poor clinical outcome in breast cancer patients

Tumor Biology ◽  
2015 ◽  
Vol 37 (1) ◽  
pp. 361-368 ◽  
Author(s):  
Sabine Krenn-Pilko ◽  
Uwe Langsenlehner ◽  
Tatjana Stojakovic ◽  
Martin Pichler ◽  
Armin Gerger ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Clinical Outcome ◽  
Cancer Patients ◽  
Neutrophil To Lymphocyte Ratio ◽  
Breast Cancer Patients ◽  
Poor Clinical Outcome ◽  
Lymphocyte Ratio

Abstract P338: Incidence, Predictors and Impact of Infarct in New Territory in Escape Na1 Trial

Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Nishita Singh ◽  
Martha Marko ◽  
Petra Cimflova ◽  
Johanna Ospel ◽  
Nima Kashani ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Clinical Outcome ◽  
Endovascular Therapy ◽  
Randomized Study ◽  
Maximum Diameter ◽  
Vascular Territory ◽  
Poor Clinical Outcome ◽  
Guide Catheter ◽  
Ct And Mri

Introduction: Infarct in new territory (INT) is a known complication of endovascular therapy. We assessed the prevalence, predictors and clinical relevance of INT Methods: We included patients from the ESCAPE-NA1: a multicenter, international randomized study that assessed the efficacy of intravenous nerinetide in patients with acute ischemic stroke who underwent EVT within 12 hours from onset. All imaging was re-evaluated, and INT was defined by presence of infarct in new vascular territory, outside the baseline target occlusion(s) on follow up CT and MRI. INT’s were classified by maximum diameter (<2mm, 2-20mm and >20mm) and location. Results: Of 1099 analyzed patients in ESCAPE NA1, 107 had INT (9.7%, mean age 67 years, 51.4% females). There were no differences at baseline in those with vs without INT. Most INTs (75.7%) were angiographically occult and 41(38.3%) were > 20mm. The most common INT territory was the ACA alone or in combination with MCA/PCA (30.3%). The presence of emboli in new territory angiographically was significantly associated with INT (OR 16.39, 95%CI 8.14-33.09). Alteplase use, balloon guide catheter use, nerinetide and initial occlusion site did not predict INT. INT patients had higher final median infarct volumes compared to non-INT (44.5cc vs 23.3cc, P<0.001). Large INT (diameter of >20mm) were associated with poor clinical outcome compared to INT (<2mm) OR (mRS 0-2) 0.17, 95%CI 0.05-0.55). Conclusion: Infarcts in new territory are common and are associated with poor outcome.

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