scholarly journals An Analytical Study on Associated Type-II Diabetic Mellitus with ABO Rhesus Blood Groups

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 264-268
Author(s):  
Ravi Kumar ◽  
Ravi Varma BH ◽  
Vijayabhasker V ◽  
Avinash Kulkarni
Keyword(s):  
Diabetes Mellitus ◽  
Blood Group ◽  
Tertiary Care ◽  
Blood Groups ◽  
Care Hospital ◽  
Type Ii ◽  
Cross Sectional ◽  
Local Populace ◽  
Control Study

Diabetes mellitus (DM) is a metabolic disorder categorized by hyperglycemia subsequent that faults of insulin emission and/or insulin cellular resistance and is the fore most reason for disease and mortality. The ABO blood collections frequently related by numerous illnesses through one blood group added repeatedly grown by the patients of a specific disease. The aim of this learning is to regulate the association among ABO & Rhesus blood groups and Type-2 diabetes mellitus in the local populace of Visakhapatnam. The present study is a hospital depended on the cross-sectional, case-control study, directed over a phase of six months in out-patient units of endocrinology department of a tertiary care hospital. An entire of 332 patients by Type-II DM and 200 age and sex harmonized healthy controls were included. In cases group, out of 332 patients 174(52.4%) were males (vs 113(56.5%) controls) and 158(47.5%) were females (vs 87(43.5%) controls) and about 289(87.04%) patients were found to be Rh+ve type (vs 178(89%) controls). About 91(27.4%) were found to be B-positive (vs 28(14%) controls), 87(26.2%) were O-positive (vs 69( 34.5%) controls ), and 73(22%) are A-positive (vs 62(31%) controls), 38(11.45%) are AB-positive (vs 19(9.5%) controls) , 14(4.2%) are O-negative(vs 3(1.5%) controls), 11(3.3%) are A-negative(vs 10(5%) controls),10(3.0%) are AB-negative(vs 3(1.5%) controls), 8(2.4%) are B-negative(vs 6(3%) controls). There is a suggestion among ABO antigens and Rhesus blood groups by Type-II DM. DM is more common in patients with B blood group and Rh-Positive.

scholarly journals Association of microvascular complications of type 2 diabetes mellitus with ABO blood group

2019 ◽  
Vol 6 (3) ◽  
pp. 738
Author(s):  
Geetika Gupta ◽  
Bhavna Langer ◽  
Tabinda Shah ◽  
Anil K. Gupta ◽  
Mumtaz Goni
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Group ◽  
Tertiary Care ◽  
Blood Groups ◽  
Vascular Complication ◽  
Abo Blood Group ◽  
Care Hospital

Background: Micro vascular complications are the major outcome of Type 2 Diabetes Mellitus progression, which reduces the quality of life and increases diabetic morbidity & mortality. As the incidence of type 2 diabetes is growing day by day; our search for its aetiology and pathogenesis is also ever growing to predict its risk factors and early screening for better care and prevention of its complications. Many studies have tried to link susceptibility of type 2 diabetes with ABO blood group though results have been inconsistent. The present study aims to analyse association of micro vascular complication with different blood groups if any.Methods: A cross sectional study was conducted among patients of type 2 diabetes Mellitus in a tertiary care hospital. Determination of ABO and Rh status was done by standard slide method of agglutination. Detailed information about age, gender, BMI, duration of diabetes, age of onset of diabetes was noted with the help of a proforma. The records (clinical examination and investigations done by physician) were screened for type of micro vascular complications.Results: Out of a total of 319 patients suffering from type 2 diabetes, 209 subjects (65.15%) had one or the other complications. A statistically significant (p=0.00) difference was observed between the presence or absence of complications in different blood groups. In patients with Blood group B, 76.14% presented with complications. Though Nephropathy was the most common complication observed among different blood groups, none of the type of micro vascular complication was found to be significantly associated with different blood groups.Conclusions: The findings in our study suggest that although there was a significant association between presence or absence of complications and different blood groups, but this association was not significant for different types of complications.

scholarly journals SURVEY OF PATTERN OF DRUG INTERACTIONS IN PATIENTS BEING PRESCRIBED ANTI-DIABETIC MEDICATIONS IN A TERTIARY CARE HOSPITAL: PROSPECTIVE CROSS SECTIONAL STUDY

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Sujeet A. Divhare ◽  
Satyashil Ingale
Keyword(s):  
Diabetes Mellitus ◽  
Drug Interactions ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Potential Ddis ◽  
Cross Sectional

Background: Potential importance of drug –drug interactions (DDIs) is increasing as polypharmacy becomes more prevalent. Because additional data on the incidence and pattern of potential DDIs among diabetic patients are lacking in India, and supplemental pharmacodynamic or clinical outcome information is needed to address importance of a drug- drug interaction. Aim and objectives: To identify and analyze the pattern of DDIs in patients being prescribed anti-diabetic drugs in a tertiary care hospital. Material and Methods: This prospective cross-sectional study was carried out for a period of three months in 200 Type 2 diabetes mellitus (Type 2 DM) patients who were taking at least one antidiabetic agent during the period of past six months, of any age and either sex admitted in medicine ward of a tertiary care teaching hospital. Only one prescription was included for each patient on his/her 3rd day of hospitalization in the ward. Results: A total of 1217 drugs were prescribed in 200 prescriptions, resulting in an average of 6.1 drugs per prescription. A total of 637 potential DDIs were noted. The majority were seen in middle aged and elderly people. No overall difference was detected in the patients on insulin or metformin therapy taking or not taking additional drugs with the potential to interact. Worse control was found in the group of patients on sulphonylurea therapy taking interacting drugs (P <0.05). This difference was most marked in the group of patients over 60 years of age, who also had the highest intake of potentially interacting drugs (57%; <35 years-37%). Conclusion: Antidiabetic drugs have numerous interactions. A good practice is to use a drug­–drug interaction checker if any questions arise, several are available online. Quality care starts with the clinician obtaining a complete medication list for each patient at the start of each visit. Keywords: diabetes mellitus, drug interactions, hypoglycemic agents, drug therapy, co-morbidity, polypharmacy

scholarly journals Anxiety among patients with diabetes mellitus evaluated using generalized anxiety disorder 7-item scale

2016 ◽  
Vol 04 (02) ◽  
pp. 133-136 ◽  
Author(s):  
Amit Thour ◽  
Ramninder Nagra ◽  
Arunjeet Gosal ◽  
Tejasav Sehrawat ◽  
Subhash Das ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Tertiary Care Hospital ◽  
Microvascular Complications ◽  
Tertiary Care ◽  
Generalized Anxiety ◽  
Care Hospital ◽  
Cross Sectional ◽  
Patients With Diabetes

Abstract Background: Anxiety has been shown to be associated with poor outcomes in people with diabetes. However, there has been limited data, especially from India, which has specifically examined whether diabetes mellitus is associated with an increased likelihood of comorbid anxiety. Aim: The aim was to estimate the prevalence of anxiety in patients with diabetes and to determine the association of anxiety with age, sex, and other related parameters. Setting: Endocrine clinic, tertiary care hospital. Design: Cross-sectional. Materials and Methods: The study was cross-sectional carried out in endocrinology clinic of tertiary care hospital in North India. Cases were patients with type 2 diabetes mellitus above 30 years of age. Anxiety was assessed using the generalized anxiety disorders 7-item (GADs-7) scale. The relationship with a sociodemographic profile, duration of diabetes, hypertension, and microvascular complications was also analyzed. Results: Seventy-three subjects (42.5% females) with mean age 50.8 ± 9.2 years were evaluated. The prevalence of anxiety was 34%. Severe anxiety (GAD-7 score ≥15) was present in three (4%) subjects, moderate anxiety (GAD-7 score ≥10) was present in six (8%) subjects, and mild anxiety was present in 16 (22%) of subjects. Anxiety increased with fasting plasma glucose, hypertension, was more in women, but the differences were not statistically significant. Conclusions: Our study demonstrates a higher prevalence of anxiety in patients with type 2 diabetes. No factor was significantly associated with anxiety. Therefore, anxiety should be assessed in each and every patient, irrespective of other factors.

scholarly journals Study of Serum Electrolytes in Type 2 Diabetes Mellitus Individuals in Rural Tertiary Care Hospital in Kancheepuram District

2021 ◽  
Vol 14 (02) ◽  
pp. 691-694
Author(s):  
V. Santhosh ◽  
D M. Gomathi ◽  
A. Khadeja Bi ◽  
S. Suganya ◽  
G. Gurulakshmi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Tertiary Care ◽  
P Value ◽  
Care Hospital ◽  
Type Ii ◽  
Serum Electrolytes ◽  
Intracellular Space

Aim: To measure the levels of Serum electrolytes (Na+, K+ ,Cl )in type II DM individuals and to compare it with healthy controls. Methods: A case control study was conducted at Medicine Department, from March 2019 to September 2019. A total of 60 patients ,comprised of 30 confirmed type II DM patients as cases and 30 healthy individuals of similar criteria were treated as controls. In both the groups,biochemical measurement of Serum electrolytes (Na+, K+ ,Cl ),FBS was studied and the results were compared. Results: Inindividuals with Diabetes mellitus sodium and chloride showed insignificant alterations.There was an increase in serum potassium levels which was found to be statistically highly significant (p-value less than or equal to 0.05) . The drift of potassium from intracellular space to extracellular space leads to Hyperkalaemia which is due torenal impairment, insulin deficiency or hypertonicity. Conclusion: This study concludes that there is significant association of potassium with hyperglycemic crisis in patients with type 2 diabetes mellitus. Thus serum electrolytes has to be routinely monitored in diabetic individuals since electrolyte derangements are markedly found in uncontrolled diabetes.

scholarly journals Prescribing pattern of oral anti-diabetic agents in type 2 diabetes mellitus patients in a tertiary care hospital

2018 ◽  
Vol 7 (5) ◽  
pp. 956
Author(s):  
Taruna Sharma ◽  
Rajit Sahai ◽  
Suman Bala ◽  
Dilip C. Dhasmana ◽  
Nidhi Kaeley
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Combination Therapy ◽  
Tertiary Care ◽  
Fixed Dose ◽  
Care Hospital ◽  
Prescribing Pattern ◽  
Cross Sectional

Background: Prescription pattern studies are a tool for assessing the prescribing, dispensing and distribution of medicines. The main aim of assessing prescribing pattern is to facilitate rational use of medicines. So the main aim of the study was to assess the prescribing pattern of oral anti-diabetic agents in type 2 diabetes mellitus, to assess the rationality of the prescribed drugs and also to assess the pattern of co-morbid conditions associated with type 2 diabetes mellitus in a tertiary care hospital.Methods: This cross sectional study was conducted in the Department of Pharmacology in collaboration with Department of General Medicine. Study was conducted from 1st June 2016 to 31st Aug 2016 (3 months). A total of 100 patients were enrolled after taking written informed consent. A structured case recording form was used to record demographic details and prescription details. The rationality of prescriptions was assessed using American Diabetes Association guidelines 2015.Results: Majority of the patients were prescribed combination therapy (54%) followed by monotherapy (46%). Oral anti-diabetic agents used as monotherapy other than metformin were inappropriate. Among the patients receiving combination therapy majority were receiving a fixed dose combination which were inappropriate.Conclusions: Majority of the patients were receiving fixed dose combinations without justifiable pharmacokinetic/pharmacodynamic benefits. Such kinds of studies are required to improve rationality of prescription of drugs, decreasing morbidity and mortality of patients and decreasing the cost of treatment.

An assessment of depression in type-II diabetics presenting at tertiary care hospital

2021 ◽  
Vol 15 (8) ◽  
pp. 2093-2095
Author(s):  
Mahwish Adnan ◽  
Ghulam Hassan ◽  
Muhammad Abdul Raziq
Keyword(s):  
Diabetes Mellitus ◽  
Behavioral Science ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
P Value ◽  
Care Hospital ◽  
Type Ii ◽  
Cross Sectional ◽  
Duration Of Diabetes ◽  
Type Ii Diabetics

Objective: To assess the frequency of depression in type-II diabetics presenting at tertiary care hospital. Materials & Methods: This cross sectional study was conducted at Department of Psychiatry & Behavioral Science, Sheikh Zayed Hospital, Rahim Yar Khan from April 2020 to October 2020 over the period of 6 months. Total 200 type-II diabetics having age 20-65 years either male or female were selected for this study. Depression was assessed in selected by using DSM-IV criteria for Depression. Results: Mean age was 54.37 ± 5.88 years. Out of 200 patients of diabetes, depression was noted in 46 (23%) patients. Most (98,49%) of the patients were between 51-65 years but difference of depression with age group was not statistically significant with p value 0.8958. Total 19 (20.88%) male patients and 27 (24.77%) female patients were found with depression. But depression was insignificantly associated with gender with p value 0.6315. Total 11 (14.29%) patients found with depression having duration of diabetes mellitus ≤3 years and 35 (28.46%) patients found with depression having duration of diabetes mellitus >3 years. Depression was significantly associated with duration of diabetes mellitus with p value 0.032. Conclusion: Our study concluded that prevalence of depression in type 2 diabetes mellitus patients was much higher and have shown positive association with extremes of ages and duration of disease. Keywords: Diabetes mellitus, depression, socioeconomic status, physical recovery

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