Acute Transverse Myelitis Associated with COVID-19 vaccine: A Case Report

2021 ◽  
Vol 12 (3) ◽  
pp. 2083-2087
Author(s):  
Ali Alshararni

The case report demonstrates the issue of Khalid Ali, who is a citizen of Yamen, explicitly living in Saudi Arabia. He is 38 years, weighs 82kgs, and of 162 cm in height. He is a sales professional and married with two kids. Khalid Ali has been living healthy until two years ago when he started experiencing pains in his lower extremities accompanied by numbness. He was treated, and everything went back to normal until soon when the case came back after the administration of the Pfizer vaccine as a preventive measure for COVID-19 disease. The consequence of the administration of the Pfizer vaccine resulted in severe pain and weaknesses in his legs and severe headache on the second day, which resulted in him being put on an ICU after 48 hours since he was almost paralyzed. A series of tests were conducted on him, including magnetic resonance imaging (MRI), hematology, and biochemistry which involved Cerebrospinal Fluid (CSF) protein test. MRI findings were significant since they indicated acute inflammation on the spine observed on the dorsal spinal cord with contrast and lumbosacral spinal cord. All the hematology tests turned out to be expected. Biochemistry conducted tests were similarly standard except for CSF protein which was highly abnormal. The combination of the high abnormal CSF protein test and acute inflammation of the spine observed from the MRI findings were confirmed evidence of acute transverse myelitis as a result of the administration of the Pfizer vaccine.

2010 ◽  
Vol 17 (1) ◽  
pp. 74-80 ◽  
Author(s):  
Gulay Alper ◽  
Kalliopi A Petropoulou ◽  
Charles R Fitz ◽  
Yeonhee Kim

Background:There is lack of reported magnetic resonance imaging (MRI) studies of idiopathic acute transverse myelitis (ATM) in children. Objective:To describe the imaging features of idiopathic ATM in children. Methods:We retrospectively analyzed the spinal MRI findings of children diagnosed with ATM. The anatomic regions, vertebral segmental length, gray or white matter involvement, cord expansion and gadolinium enhancement were examined. Results:A total of 27 children were diagnosed with isolated monophasic ATM with a mean follow-up of 5.2 years. Two children later diagnosed with neuromyelitis optica were excluded from the pediatric ATM cohort. None of the patients had a subsequent diagnosis of multiple sclerosis. The mean age of onset was 9.5 years (0.5–16.9 years). Spinal MRIs were abnormal in 21 (78%). The mean interval between symptom onset and the MRI was 1.7 days (0–19 days). Central cord hyperintensity involving gray matter was seen in all patients. A majority (67%) of the patients demonstrated long segment lesions with a mean segment length of 6.4. Conclusions:We conclude that central cord inflammation extending over three or more segments is the most common finding of idiopathic monophasic transverse myelitis in children. The risk of multiple sclerosis in children who experience isolated transverse myelitis as a first demyelinating event is low.


2021 ◽  
Vol 9 (06) ◽  
pp. 476-479
Author(s):  
Mohammed Ajamat ◽  
◽  
Kadira Abdi ◽  
Aziz Ahizoun ◽  
Youssouf Benmoh ◽  
...  

Spinal cord neurological disorders associated with Hashimotos disease are rare and very rarely described.Thediagnosis is based on a set of arguments with the performance of an exhaustive assessment in order to eliminate other possible causes of medullary neurological damage. In this case, we report a 21 years old man, who was admitted for a spinal cord syndrome with D12-L1 sensory level and was diagnosed with acute transverse myelitis associated with Hashimotos thyroiditis. The evolution was favorable with regression of the symptomatology after bolus of corticoids followed by oral corticotherapy.


Author(s):  
Thomas Scott ◽  
Norbert Weikers ◽  
Mark Hospodar ◽  
Joseph Wapenski

Abstract:The prognostic value of magnetic resonance imaging (MRI) in the syndrome of acute transverse myelitis had not been evaluated. After retrospective study of 14 cases, we found that MRI is valuable for both diagnosis and prognosis in this illness. The criteria for the diagnosis of acute transverse myelitis consisted of acute onset (over less than 3 weeks) of symmetrical motor and sensory dysfunction referable to a distinct spinal cord level, with sphincter dysfunction. Patients with abnormal MRIs of the spinal cord had significantly worse outcomes than patients with normal MRIs.


2001 ◽  
Vol XXXIII (3-4) ◽  
pp. 52-54
Author(s):  
V. V. Ponomarev ◽  
V. I. Khodulev

Acute primary myelitis is an inflammatory disease of the spinal cord. Transverse and multifocal myelitis is distinguished, differing in the size and number of foci of inflammation in individual segments of the spinal cord. Acute transverse myelitis is considered as a separate nosological form in the 10th revision of the International Classification of Diseases. The introduction of such modern paraclinical examination methods as electroneuromyography (ENMG), magnetic resonance imaging (MRI), make it possible to visualize the morphological substrate of the disease, to better understand the nature and mechanisms of its development.


Author(s):  
Haruki Funao ◽  
Satoshi Nakamura ◽  
Kenshi Daimon ◽  
Norihiro Isogai ◽  
Yutaka Sasao ◽  
...  

1997 ◽  
Vol 37 (4) ◽  
pp. 247-248 ◽  
Author(s):  
Tomihiro Imai ◽  
Hiroyuki Matsumoto ◽  
Yukiko Ohkubo ◽  
Hirohiko Shizukawa ◽  
Susumu Chiba ◽  
...  

2014 ◽  
Vol 27 (02) ◽  
pp. 155-158 ◽  
Author(s):  
U. Geissbühler ◽  
P. Karli ◽  
F. Forterre ◽  
E. Linon

SummaryA two-year-old female Lucerne Hound was presented with a one-week history of signs of progressive neck pain, inappetence, apathy, and an elevated rectal temperature. Findings of magnetic resonance imaging (MRI) were consistent with a foreign body abscess in the epidural space at the level of the first and second cervical vertebrae. A leftsided dorso-lateral atlantoaxial approach was performed, revealing an epidural abscess containing a grass awn. The clinical signs resolved within three days of surgery and the dog made a full recovery. This case report shows that grass awns can migrate to the atlantoaxial region in dogs and MRI findings lead to a suspicion of caudo-cranial migration within the spinal canal.


2021 ◽  
Vol 14 (1) ◽  
pp. e238992
Author(s):  
Katherine Thornley ◽  
Carlo Canepa

An 80-year-old, previously healthy patient presents with acute transverse myelitis with sensory level at T8. The MRI scan of the spinal cord showed longitudinal extensive transverse myelitis, and she tested positive for aquaporin 4 antibodies in serum. She received treatment with intravenous and oral steroids, with no improvement and then underwent plasma exchange. She was then started on azathioprine for prevention of relapses, while continuing physiotherapy and occupational therapy. Eventually, she was transferred to a specialised spinal cord centre for long-term rehabilitation.


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