scholarly journals Odontogenic Cysts and Tumors of Maxilla and Maxillary Sinus (A Clinicopathological Analysis)

2021 ◽  
Vol 33 (4) ◽  
pp. 38-43
Author(s):  
Shahad A Waheed ◽  
Taghreed F Zaidan ◽  
Bashar H Abdullah
Keyword(s):  
Maxillary Sinus ◽  
Dentigerous Cyst ◽  
Clinicopathological Features ◽  
Odontogenic Cysts ◽  
Radicular Cyst ◽  
Impacted Tooth ◽  
Clinicopathological Analysis ◽  
Male Patients ◽  
The Mean ◽  
Similarities And Differences

Background: Knowledge about the prevalence and distribution of pathologies in a particular location is important when a differential diagnosis is being formulated. The aim of this study was to describe the prevalence and the clinicopathological features of odontogenic cysts and tumors affecting the maxilla and to discuss the unusual presentation of those lesions within maxillary sinus. Materials and Methods: A multicenter retrospective analysis was performed on pathology archives of patients who were diagnosed with maxillary odontogenic cysts and tumors from 2010 to 2020. Data were collected with respect to age, gender and location. Result: A total of 384 cases was identified, 320 (83.3%) cases were diagnosed as odontogenic cysts and 64 (16.6%) as odontogenic tumors. The mean age was 30.5 years with a standard deviation of 16.2 years. Male patients were more commonly affected (n=220, 57.3%). Radicular cyst was the most common cyst (n=205, 64.1%), while the most common tumor was odontoma (n=14, 21.9%) and dentigerous cyst was the most common lesion to present within the maxillary sinus. Conclusion: This study indicates that there are some geographic similarities and differences in regard to distribution of odontogenic cysts and tumors in maxilla and it raises awareness of their presentation within maxillary sinus especially if there is an association with an ectopic or adjacent impacted tooth.

scholarly journals Immunohistochemical Expression of CDC7 in Dentigerous Cyst, Odontogenic Keratocyst and Radicular Cyst

2018 ◽  
Vol 61 (1) ◽  
pp. 17-21
Author(s):  
Zohreh Jaafari-Ashkavandi ◽  
Ahmad Alipour Tuyeh ◽  
Sepideh Assar
Keyword(s):  
Dentigerous Cyst ◽  
Odontogenic Cysts ◽  
Radicular Cyst ◽  
Immunohistochemical Expression ◽  
Serine Threonine Kinase ◽  
Threonine Kinase ◽  
Dentigerous Cysts ◽  
Pathologic Lesions ◽  
The Mean ◽  
Post Hoc

CDC7 is a serine/threonine kinase which has an essential role in initiation of DNA proliferation and S phase. It increases the invasion and proliferation in many pathologic lesions. This study aimed to evaluate the expression of CDC7 in the most common odontogenic cysts. We evaluated 17 dentigerous cysts, 18 odontogenic keratocysts (OKC) and 13 radicular cysts immunohistochemically. The mean expression of CDC7 was analyzed using ANOVA and Post-HOC methods. All specimens revealed CDC7 expression. Higher expression of CDC7 in OKC and radicular cyst was shown in comparison to dentigerous cyst (P < 0.001), while radicular cyst and OKC groups showed no difference in CDC7 expression (P = 0.738). The high expression of CDC7 in OKC suggests that this protein could be related to the higher proliferation rate and invasiveness of OKC. On the other hand, the higher CDC7 expression in radicular cyst may simply be related to inflammation as this cyst is neither aggressive nor invasive.

scholarly journals MASSIVE DENTIGEROUS CYST INVOLVING THE ENTIRE RIGHT MAXILLA - A CASE REPORT

2019 ◽  
pp. 1-2
Author(s):  
K. S Manjunath
Keyword(s):  
Case Report ◽  
Dentigerous Cyst ◽  
Odontogenic Cyst ◽  
Odontogenic Cysts ◽  
Radicular Cyst ◽  
Impacted Tooth ◽  
Unerupted Tooth ◽  
Dentigerous Cysts ◽  
Enamel Epithelium ◽  
Reduced Enamel Epithelium

The Dentigerous cysts are odontogenic cysts which originates from reduced enamel epithelium in an unerupted tooth or it encloses the crown of an unerupted or impacted tooth at cementoenamel junction, it is estimated to about 20% of all epithelium lined cysts and 2nd most common odontogenic cyst after radicular cyst. Here is a case report of dentigerous cyst of right maxilla which has been discussed below.

scholarly journals Cistos e tumores odontogênicos: estudo retrospectivo dos casos diagnosticados no período de 10 anos em um hospital no sul do Brasil

2021 ◽  
Vol 62 (1) ◽  
pp. 56-62
Author(s):  
Bruna Luísa Neumann ◽  
Stéfanie Thieme ◽  
Amanda De Farias Gabriel ◽  
Virgilio Gonzales Zanella ◽  
Felipe Martins Silveira ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Medical Records ◽  
Dentigerous Cyst ◽  
Odontogenic Tumors ◽  
Odontogenic Cysts ◽  
Histopathological Diagnosis ◽  
Radicular Cyst ◽  
Pathological Characteristics ◽  
The Mean ◽  
Odontogenic Neoplasm

Introduction: odontogenic lesions (OLs) represent a heterogeneous group of oral and maxillofacial pathologies presenting distinct characteristics. The present study aimed to identify the clinical and pathological characteristics of OLs diagnosed in a southern Brazilian hospital. Materials and methods: a retrospective study was performed to evaluate cases with histopathological diagnosis of OLs identified in the period between 2007 and 2017. The patient's medical records were evaluated in order to obtain the clinical and pathological characteristics and the histopathological diagnosis from each case. Results: a total of 255 cases of OLs were identified. From these, 197 (77%) odontogenic cysts and 58 (23%) odontogenic tumors were surveyed, with only one case (0,39%) of a malignant odontogenic neoplasm. The most prevalent diagnosis were radicular cyst (32.5%) and dentigerous cyst (31.76%), followed by odontogenic keratocyst (10.98%), odontoma (10%) and ameloblastoma (10%). The majority of the cases affected the mandible (53.7%) with a slight preference by female individuals (51%). The mean age was 34±20.53 years old. Discussion: the presented data are in accordance with the literature regarding the rarity of the diagnosis of odontogenic tumors. Conclusion: the present study demonstrated the main clinical and pathological characteristics of OLs diagnosed in a southern Brazilian hospital, contributing to a better understanding of these injuries profiles.

scholarly journals Dentigerous cyst in the maxilla: case report in a pediatric patient

2021 ◽  
Vol 10 (16) ◽  
pp. e143101623293
Author(s):  
Bianca de Fatima Borim Pulino ◽  
Raphael Capelli Guerra ◽  
Gabriel Cunha Collini ◽  
Marcello Cheloti ◽  
Eduardo Hochuli Vieira
Keyword(s):  
Pediatric Patient ◽  
Alveolar Bone ◽  
Treatment Plan ◽  
Dentigerous Cyst ◽  
Odontogenic Cysts ◽  
Long Period ◽  
Unerupted Tooth ◽  
Dentigerous Cysts ◽  
Male Patients ◽  
Almost All

Dentigerous cysts are the second most common odontogenic cysts of the jaws, and sometimes inhibit the eruption of teeth. Almost all of the dentigerous cyst encloses the crown of an unerupted tooth and the radiolucent area is attached to the tooth at the cementoenamel junction. Dentigerous cyst is more common in male patients and most commonly develop in the second and third decades of life. Clinically, a localized swelling of the alveolar bone can be detected, however, dentigerous cysts can be asymptomatic during a long period of time, leading to a significant destruction of bone. The conventional treatment plan is cyst removal and marsupialization. Marsupialization therapy can be useful to promote the spontaneous eruption of the involved tooth within the cyst. However, tooth eruption does not always occur spontaneously after marsupialization. This article aims to report a clinical case of the diagnosis and treatment of a dentigerous cyst in the maxilla associated with an unerupted canine in a pediatric patient and discussion of the treatment performed.

scholarly journals Clinical and Histopathological Concordance of oral Bone Lesions. Retrospective Study

2019 ◽  
pp. 307-317
Author(s):  
Yadira V. Boza Oreamuno DDS, MSc ◽  
Andrea López Soto DDS, MSc
Keyword(s):  
Retrospective Study ◽  
Clinical Diagnosis ◽  
Dentigerous Cyst ◽  
Bone Lesions ◽  
Odontogenic Cysts ◽  
Histopathological Diagnosis ◽  
Radicular Cyst ◽  
Anterior Maxilla ◽  
Kappa Test ◽  
Periapical Granuloma

Bone lesions of the jaws have their origin from odontogenic and non-odontogenic structures. They can be benign or malignant, asymptomatic, they can be located around the root of the tooth, around the crown and in the interradicular area or they may not be related to the teeth. OBJECTIVE: to determine the frequency of the different bone lesions and the concordance between the clinical and histopathological diagnosis, in the clinical internship of the Faculty of Dentistry of the University of Costa Rica (UCR). METHODOLOGY: retrospective study of bone lesions recovered from the biopsy archive of the Faculty of Dentistry of the UCR from 2008 to 2015. Information on sex, age, location of the lesion, clinical diagnosis and diagnosis were evaluated and described. The agreement between the clinical and histopathological diagnosis was verified by the Kappa test. RESULTS: The 77 cases of oral bone lesions preferentially affected men 53.8% (n=41), the average age was 34.7 years (s.d.±19.6) and with lesions predominantly located in the posterior jaw 36.4% (n=28) and anterior maxilla 35.1% (n=27). Odontogenic cysts (OC) 42.9% (n=33), non-specific or unclassified diagnosis 28.6% (n=22) and inflammatory lesions of pulp and periapical origin 14.2% (n=11). TOs accounted for 7.8% (n=6) of the lesions. The four most predominant lesions were the radicular cyst, nonspecific diagnosis, dentigerous cyst and periapical granuloma. Concordance with the first diagnostic hypothesis was presented in 24 (31.2%) cases, the value of Kappa was 0.274 (discrete concordance) and 20.8% without clinical diagnosis only a description of the lesion. CONCLUSIONS: The OC were the predominant; being individually the radicular cyst the most frequent lesion. The clinical and histopathological concordance was discrete.

scholarly journals Immunohistochemical expression of Cyclooxygenase 2 reflects the proliferative activity in the epithelium of odontogenic lesions

2022 ◽  
Vol 10 (1) ◽  
Author(s):  
Vani Verma ◽  
Chetana Chandrashekar ◽  
Raghu Radhakrishnan ◽  
Monica Charlotte Solomon
Keyword(s):  
Epithelial Cells ◽  
Dentigerous Cyst ◽  
Cyclooxygenase 2 ◽  
Odontogenic Keratocyst ◽  
Odontogenic Cysts ◽  
Radicular Cyst ◽  
Chi Square ◽  
Ki 67 ◽  
Odontogenic Epithelium ◽  
Cox 2

Purpose:  Odontogenic cysts and tumors comprise a major component of lesions of the oral and maxillofacial region. The pathogenesis of these lesions involves the interaction between the odontogenic epithelium and the ectomesenchyme. However, the clinical behavior of these biological entities is unpredictable. The aim of this study was to evaluate the role of Cyclooxygenase 2 (COX-2) in the pathogenesis and prognostication of odontogenic lesions.Material and method:  : In this study formalin-fixed paraffin-embedded tissue section of Odontogenic Keratocyst (n=10) Dentigerous cyst (n=10), Radicular cyst (n=10) and unicystic ameloblastoma (n=10) were immunohistochemically stained with COX-2 (NCL2-COX-2- 4H12) and with Ki 67 (Ki-67 GM001) using standard staining protocols. The cytoplasmic expression of COX-2 in all the lesions was semi-quantitatively assessed. The pattern of expression of COX-2 among the different odontogenic lesions was statistical analyzed using the ANOVA test and the chi-square test.Results: All the 40 odontogenic lesions that were evaluated expressed COX-2 immunohistochemically. A high number of odontogenic epithelial cells expressed COX-2 in most of the odontogenic keratocyst, radicular cyst and unicystic ameloblastomas. The expression of COX-2 was significantly (p=0.036) higher in Unicystic Ameloblastomas and Radicular cyst compared to that of Odontogenic Keratocyst and the dentigerous cyst.Conclusion: The recognition that expression of COX-2 by odontogenic epithelial cells may indeed shed a new light on the biological mechanisms involved in the development of these benign yet aggressive lesions of the jaws. An insight into the molecular interactions occurring in the odontogenic epithelium will aid in better management of these lesions. 

scholarly journals Ki-67 and MCM-2 in Dental Follicle and Odontogenic Cysts: The Effects of Inflammation on Proliferative Markers

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Nurhan Güler ◽  
Nil Çomunoğlu ◽  
Fatih Cabbar
Keyword(s):  
Dentigerous Cyst ◽  
Squamous Metaplasia ◽  
Periodic Acid ◽  
Mucous Cell ◽  
Glandular Epithelium ◽  
Odontogenic Cysts ◽  
Dental Follicle ◽  
Ki 67 ◽  
Periodic Acid Schiff ◽  
The Mean

The aim of this study was to investigate whether there is any association between inflammation and the expression of markers of cell cycle entry (Ki-67 and MCM-2) in dental follicle (DF) of asymptomatic impacted teeth and odontogenic cysts. The study consisted of 70 DFs and 20 odontogenic cysts (radicular cyst (RC), dentigerous cyst (DC) and keratocytic odontogenic tumor (KCOT) located at posterior mandibular region. Histological findings of inflammation for all specimen and mucous cell prosoplasia, squamous metaplasia, glandular epithelium for all DFs were stained with hematoxyline and eosin, periodic acid schiff, alcian blue, and mucin. Epithelial cell proliferation was determined by using immunohistochemical labeling for Ki-67 and MCM-2. The histologic examinations showed 16% mucous cell prosoplasia, 54% squamous metaplasia, 20% glandular epithelium, 37% inflammation. Inflammation was detected in all RCs and %62 in DF, %43 in DC and KCOT. Positive correlation was found between the inflammation of DF and odontogenic cysts (P<0.01). The mean Ki-67 and MCM-2 expressions were found9,64±5,99and6,34±3,81in DF,11,85±9,01and13,6±9,94in odontogenic cysts, respectively. While the mean Ki-67 expressions were statistically significant in DF and KCOT (P<0.01), MCM-2 were significant in RC and KCOT (P<0.01). MCM-2 expresion in RCs were statistically significant than KCOT (P<0.01). The results of this study indicated that the higher MCM-2 expressions in RC than the KCOT might be related to the inflammation and this protein might be more sensitive to inflammation.

Large Dentigerous Cyst of the Maxillary Sinus and Absence of Impacted Tooth

2015 ◽  
Vol 26 (7) ◽  
pp. 2227-2228
Author(s):  
Serhan Derin ◽  
Murat Sahan ◽  
Neşat Cullu ◽  
Hamdi Sozen ◽  
Serkan Yasar Celik
Keyword(s):  
Maxillary Sinus ◽  
Dentigerous Cyst ◽  
Impacted Tooth

scholarly journals Dentigerous cyst arising from a denticle in a primary teeth- a rare case report with brief review of literature

2021 ◽  
Author(s):  
Jimsha Kumaran ◽  
Jonathan Mariappan
Keyword(s):  
Primary Teeth ◽  
Dentigerous Cyst ◽  
Odontogenic Cysts ◽  
Review Of Literature ◽  
Impacted Tooth ◽  
Odontogenic Epithelium ◽  
Dentigerous Cysts ◽  
Rare Case Report ◽  
Enamel Epithelium ◽  
Reduced Enamel Epithelium

Odontogenic cysts are derived from odontogenic epithelium which may develop before or after the formation of tooth. Most of these are developmental in origin. While dentigerous cysts are common odontogenic cysts that are related to the crown of the impacted tooth and known to arise from reduced enamel epithelium.

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