scholarly journals Positive Interference of Hemolysis on Kaliemia Dosage Corresponding to Hemolysis Degree on Bs 300

2020 ◽  
Vol 03 (01) ◽  
Author(s):  
Miora Koloina Ranaivosoa ◽  
Tinà Rakotoniaina ◽  
Valdo Rahajanirina ◽  
Tahinamandranto Rasamoelina ◽  
Zely Arivelo Randriamanantany ◽  
...  
Keyword(s):  
Positive Interference

scholarly journals Genetic Control of Mammalian Meiotic Recombination. I. Variation in Exchange Frequencies Among Males From Inbred Mouse Strains

Genetics ◽  
2002 ◽  
Vol 162 (1) ◽  
pp. 297-306 ◽  
Author(s):  
Kara E Koehler ◽  
Jonathan P Cherry ◽  
Audrey Lynn ◽  
Patricia A Hunt ◽  
Terry J Hassold
Keyword(s):  
Meiotic Recombination ◽  
Inbred Mouse ◽  
Inbred Strains ◽  
Male Meiosis ◽  
Mouse Strains ◽  
Recombination Rates ◽  
The Mean ◽  
Genetic Background Effects ◽  
Exchange Patterns ◽  
Positive Interference

AbstractGenetic background effects on the frequency of meiotic recombination have long been suspected in mice but never demonstrated in a systematic manner, especially in inbred strains. We used a recently described immunostaining technique to assess meiotic exchange patterns in male mice. We found that among four different inbred strains—CAST/Ei, A/J, C57BL/6, and SPRET/Ei—the mean number of meiotic exchanges per cell and, thus, the recombination rates in these genetic backgrounds were significantly different. These frequencies ranged from a low of 21.5 exchanges in CAST/Ei to a high of 24.9 in SPRET/Ei. We also found that, as expected, these crossover events were nonrandomly distributed and displayed positive interference. However, we found no evidence for significant differences in the patterns of crossover positioning between strains with different exchange frequencies. From our observations of >10,000 autosomal synaptonemal complexes, we conclude that achiasmate bivalents arise in the male mouse at a frequency of 0.1%. Thus, special mechanisms that segregate achiasmate chromosomes are unlikely to be an important component of mammalian male meiosis.

An alternative method for assaying cerebrospinal fluid protein in the presence of methotrexate.

1988 ◽  
Vol 34 (10) ◽  
pp. 2091-2092 ◽  
Author(s):  
L M Kasper ◽  
W R Moorehead ◽  
T O Oei ◽  
M Markanich
Keyword(s):  
Cerebrospinal Fluid ◽  
Hydrochloric Acid ◽  
Trichloroacetic Acid ◽  
Dilute Hydrochloric Acid ◽  
Constant Amount ◽  
Manual Method ◽  
Turbidimetric Method ◽  
Methotrexate Concentration ◽  
Cerebrospinal Fluid Protein ◽  
Positive Interference

Abstract Therapeutic concentrations of methotrexate can cause significant positive interference in cerebrospinal fluid (CSF) protein values when assayed in the Du Pont aca. Conversely, our modified turbidimetric method, in which trichloroacetic acid (TCA) plus a sample blank containing dilute hydrochloric acid is used in place of TCA, exhibits little or no interference from methotrexate. This was verified by assaying solutions that contained a constant amount of protein (approximately 430 mg/L) and various amounts of methotrexate (0.0-2.3 x 10(-4) mol/L) by both the Du Pont aca and the manual turbidimetric method. As expected, the aca results showed increasing protein values with increasing methotrexate, whereas the manual method gave results approximating the expected protein value irrespective of the methotrexate concentration.

Interference by anti-immunoglobulin G antibodies in immunoradiometric assays of thyrotropin involving mouse monoclonal antibodies.

1987 ◽  
Vol 33 (6) ◽  
pp. 840-844 ◽  
Author(s):  
M H Zweig ◽  
G Csako ◽  
C C Benson ◽  
B D Weintraub ◽  
B B Kahn
Keyword(s):  
Monoclonal Antibodies ◽  
Immunoglobulin G ◽  
Serum Antibodies ◽  
Mouse Immunoglobulin ◽  
Sandwich Type ◽  
Positive Interference ◽  
Antibody Excess

Abstract "Sandwich"-type assays are subject to positive interference by the patient's "heterophile" antibodies. If present, these bind to the animal immunoglobulins in the assay reagents, forming artefactual sandwiches indistinguishable from those formed with the analyte itself. Immunoglobulins from non-immunized animals, added to the assay reagents, can diminish this effect by blocking the patient's antibodies. Elsewhere, we studied several patients with anti-mouse immunoglobulin activity, whose serum gave spuriously high results for thyrotropin (TSH) concentrations. Here we have studied this phenomenon by adding, to pooled zero-TSH serum, antibodies to mouse, goat, and horse immunoglobulins and then assaying TSH by several other sandwich-type assays involving mouse monoclonal antibodies. Assays not supplemented with blocking immunoglobulins from mice or other animals were more susceptible to this effect. When large amounts of antibody were added, the antibody excess diminished the interference. However, the presence of blocking immunoglobulins could reverse such antibody excess, actually enhancing, instead of diminishing, the positive interference. Users should be aware that blocking immunoglobulins may diminish but not necessarily eliminate this problem with such assays.

HemoCue: Evaluation of a Portable Photometric System for Determining Glucose in Whole Blood

1992 ◽  
Vol 38 (8) ◽  
pp. 1479-1482 ◽  
Author(s):  
L Ashworth ◽  
I Gibb ◽  
K G Alberti
Keyword(s):  
Whole Blood ◽  
Glucose Dehydrogenase ◽  
Glucose Measurement ◽  
Photometric System ◽  
Analytical Recovery ◽  
Wide Range ◽  
Regression Slopes ◽  
High Concentrations ◽  
Better Than ◽  
Positive Interference

Abstract We assessed the HemoCue system for measuring glucose in 5 microL of whole blood. A glucose dehydrogenase-based reaction is used with dried reagents contained in disposable microcuvettes, which are filled with blood by capillary action. Automated hexokinase and YSI 23AM glucose analyzer methods were used for comparison. Overall imprecision (CV) was better than 4.5%, with no significant differences in results between three different HemoCue photometers and four batches of microcuvettes. Regression slopes (+/- SE) were 0.947 (0.011) with the YSI and 0.966 (0.015) with the hexokinase method. Analytical recovery of added glucose was 101-106%, and the system functioned with hematocrits up to 0.65. Bilirubin up to 453 mumol/L did not interfere, but high concentrations of endogenous (greater than 3 mmol/L) and exogenous triglycerides gave positive interference. The system proved stable and robust under a wide range of storage and handling conditions; performance was impaired only at high ambient temperature (37 degrees C). We conclude that the HemoCue system should prove useful for glucose measurement; further testing outside the laboratory is warranted.

scholarly journals Bidirectional (Negative/Positive) Interference of Oleandrin and Oleander Extract on a Relatively New LOCI Digoxin Assay

2013 ◽  
Vol 140 (suppl 1) ◽  
pp. A125-A125
Author(s):  
Kerry J. Welsh ◽  
Jeffrey K. Actor ◽  
Amitava Dasgupta
Keyword(s):  
Positive Interference

Positive Interference

Science ◽  
2003 ◽  
Vol 299 (5615) ◽  
pp. 1941e-1941
Keyword(s):  
Positive Interference

scholarly journals English-Russian Hybrid Words in Translated Text: On Linguistic Interference and Norms of Translation

2020 ◽  
pp. 86-98
Author(s):  
Liliya Nefedova ◽  
Ekaterina Krasnopeyeva
Keyword(s):  
Qualitative Study ◽  
Open Source ◽  
English Language ◽  
Translation Studies ◽  
Direct Result ◽  
Sociology Of Translation ◽  
Linguistic Interference ◽  
The Subject ◽  
Descriptive Approach ◽  
Positive Interference

The article discusses the influence of Russian-English functional bilingualism of IT and tech specialists on the formation of translation norms in the corresponding field. The research is carried out within the framework of sociology of translation and descriptive approach in translation studies. It investigates the patterns in the usage of hybrid lexemes combining Russian and English graphemes, e.g. IoT-устройство (IoT-device), API-интерфейс (API-interface) and Open Source-приложение (open source application) in translations. Methodologically, the study resorts to the theoretical stance of sociology of translation, namely the concepts of translation norm, represented in the works by G. Toury and A. Chesterman, translator's habitus and the field of translation, as well as corpus-based methodology. It utilizes a comparable corpus of translated and non-translated articles published by Russian IT business magazines itWeek, Computerworld and Novosti Elektroniki (Electronics News) in 2017. Hybrids are shown to be more common in non-translated text, which can be viewed as an aspect of the expectancy norm. Qualitative study revealed the following patterns in hybrid usage in translation. Most of the hybrids used in translation are the direct result of the transfer of original English analytical structures. Hybrids are also used in translation as part of pragmatic positive interference, which shows the translator's reliance on the recipient's extensive background knowledge of the subject, as well as command of the English language. Interference, both positive and negative, is argued to be the aspect of the expectancy norm present in the field of technology-oriented media translation.

scholarly journals Competing Pressures in Diglossia: Avoiding Colloquial Elements in Writing Modern Standard Arabic

1970 ◽  
Vol 13 ◽  
pp. 146-168
Author(s):  
Alexander Magidow
Keyword(s):  
Avoidance Behavior ◽  
Regional Variation ◽  
Native Speakers ◽  
Multiple Choice ◽  
Modern Standard Arabic ◽  
Negative Interference ◽  
Standard Arabic ◽  
Positive Interference ◽  
Modern Standard

This article investigates speaker choice of variant lexemes and structures when writing in formal Modern Standard Arabic, using a multiple-choice survey that was distributed to 28 native speakers of Damascene Arabic. The study finds that speakers tend to avoid elements that are common in their local colloquial dia-lect, even if they are attested and permissible in Modern Standard Arabic, what might be called “negative interference.” However, in some cases interference from the colloquial form is so strong that speakers appear to be confused as to which form is correct (“positive interference”), and when given the choice, prefer to avoid problematic forms altogether. These results suggest that there are a number of competing pressures in diglossia, supplementing previous studies which have primarily found evidence of positive interference from the local dialects on Modern Standard Arabic. This study concludes that this avoidance behavior may explain the historical robustness of diglossia, as well as some of the regional variation that occurs in Modern Standard Arabic.

Sign in / Sign up

Export Citation Format

Share Document