scholarly journals A New Pentacyclic Triterpenoid from Albizia lebbekoides (DC) Benth (Leguminosae)

KIMIKA ◽  
2021 ◽  
Vol 32 (2) ◽  
pp. 41-46
Author(s):  
Yohannes Woldemariam ◽  
Irene Villaseñor
Keyword(s):  
The Philippines ◽  
Hexane Extract ◽  
Chromatographic Purification ◽  
Spectral Analyses ◽  
Related Literature ◽  
Pentacyclic Triterpenoid ◽  
Isolated Compound ◽  
Liquid Chromatographic

Albizia lebbekoides (DC) Benth is one of the five species of the genus Albizia found in the Philippines. Not much is known about the chemistry and potential uses of this species. Solvent partition followed by sequential and repeated liquid chromatographic purification over silica led to the isolation of a compound from the hexane extract of A. lebbekoides leaves. A review of related literature and spectral analyses showed that the isolated compound is a new pentacyclic triterpenoid with an oleanane skeleton. Its structure was determined as 3β, 16α-dihydroxyolean-6(7),12(13)-dien-28-oic acid.

The Living Experience of Suffering: A Parse Method Study

2018 ◽  
Vol 31 (4) ◽  
pp. 346-354 ◽  
Author(s):  
Teodora Duarte-Quilao ◽  
Françoise V. Maillard Strüby
Keyword(s):  
Research Method ◽  
The Philippines ◽  
Related Literature ◽  
Parse Method ◽  
Parse Research Method

This study aimed to explore the phenomenon of suffering as viewed from the humanbecoming paradigm. The Parse research method was used for this study and answers the question: What is the structure of the living experience of suffering? The participants were 10 individuals who experienced one of the most dreadful typhoons in the archipelago of the Philippines. The central finding of the study was as follows: Suffering is penetrating disheartenment amid resoluteness, as pondering with diverse alliances surfaces with lingering glimmers of destruction. The findings are discussed in relation to the humanbecoming paradigm and related literature.

Selective high-performance liquid chromatographic purification of bispecific monoclonal antibodies

1992 ◽  
Vol 599 (1-2) ◽  
pp. 13-20 ◽  
Author(s):  
Laura Tarditi ◽  
Maria Camagna ◽  
Anna Parisi ◽  
Cristina Vassarotto ◽  
Lucia B. DeMonte ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
High Performance ◽  
High Performance Liquid Chromatographic ◽  
Chromatographic Purification ◽  
Liquid Chromatographic

scholarly journals Anti-hypercholesterolemic agent from Indonesian rice bran

2019 ◽  
Vol 10 (4) ◽  
pp. 2733-2738
Author(s):  
Syaikhul Aziz ◽  
Elfahmi ◽  
Andreanus Andaja Soemardji ◽  
Sukrasno
Keyword(s):  
Solvent Extraction ◽  
Ethyl Acetate ◽  
Mass Spectroscopy ◽  
Rice Bran ◽  
Total Cholesterol Level ◽  
Hexane Extract ◽  
Binary Solvents ◽  
Serum Total Cholesterol Level ◽  
Isolated Compound ◽  
Acetone Hexane

This research was conducted to determine the total oryzanol content of various extracts and bioassay-guided isolation of active anti-hypercholesterolemic agent from Indonesian rice bran. Hot solvent extraction was done by reflux method using single and binary solvents, namely hexane, chloroform, ethyl acetate, dichloromethane, isopropanol, acetone, hexane-ethyl acetate (1:1, v/v), hexane-isopropanol (1:1, v/v), and chloroform-ethyl acetate (1:1, v/v). TLC densitometric was used to quantitatively analyze the total oryzanol content in various extracts. The hexane extract was selected for fractionation and evaluated for their anti-hypercholesterolemic activity. The structure of an isolated compound was determined on the basis of NMR and Mass spectroscopy. The total oryzanol content was obtained using various solvents ranging from 27.92 to 43.59 mg/100g rice bran, in which hexane extract showed the highest amount (43.59 ± 3.36 mg/100g rice bran). β-sitosterol has been isolated from rice bran hexane extract, which shows a significant decrease in serum total cholesterol level. In summary, hexane is the best solvent to extract oryzanol compound using reflux method, and β-sitosterol was suspected to be responsible for anti-hypercholesterolemic activity in addition to existing compound such as oryzanol that contained in the rice bran.

scholarly journals Isolation of stigmasterol from hexane extract of leaves of Pisonia grandis R.Br, in vitro anti-diabetic and its molecular docking studies

2020 ◽  
Vol 11 (2) ◽  
pp. 2117-2122
Author(s):  
Abhijit Mitra ◽  
Mohankumar Ramasamy ◽  
Valentina Parthiban ◽  
Thottempudi Ravi Teja ◽  
Srikalyani Vemuri ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Docking Studies ◽  
Hexane Extract ◽  
Medicinal Uses ◽  
Isolation And Purification ◽  
Molecular Docking Studies ◽  
Ic50 Value ◽  
Isolated Compound ◽  
Pisonia Grandis

Pisonia grandis R.Br belonging to the family Nyctaginaceae is a widely distributed evergreen tree in India known for its medicinal uses. The study was aimed to investigate the anti-diabetic property in the leaves of Pisonia grandis R.Br. The isolation and purification were performed by the conventional column chromatography and the resultant yield was found to be a white crystalline powder, which was further subjected for characterization through IR, 1H NMR, 13C NMR and Mass spectroscopy. From the characterization data, the isolated compound was identified as stigmasterol, it was first time isolated from the hexane extract of the leaves. The α-amylase inhibitory activity of stigmasterol from the hexane extract of the leaves of Pisonia grandis R.Br showed high potent activity with an IC50 value of 46μg/ml. The anti-diabetic activity of the compound against α-amylase and four other diabetic enzymes- α-glucosidase acid phosphatase, endo-β-N acetaglucosaminidase and β-glucuronidase were further investigated by molecular docking studies and proved that stigmasterol can be a potential anti-diabetic agent.

scholarly journals Isolation of Betulinic acid from the stem bark and root of Uapaca guineensis

2017 ◽  
Vol 4 (1) ◽  
Author(s):  
Abdulrazaq Ogunmoye
Keyword(s):  
Betulinic Acid ◽  
Antioxidant Properties ◽  
Ethanol Extract ◽  
2D Nmr ◽  
Stem Bark ◽  
Evergreen Forest ◽  
Spectra Analysis ◽  
Pentacyclic Triterpenoid ◽  
Ethanol Extracts ◽  
Isolated Compound

Uapaca guineensis Mull. Arg. (Euphorbiaceae) commonly called false mahogany and “Ewe akun” in the western part of Nigeria grows in humid localities, mixed evergreen forest and sea-level up to 1100 m altitude. The study was designed to isolate Betulinic acid (3?-hydroxylup-20-(29)-en-28-oic acid) which is a naturally occurring pentacyclic triterpenoid that exhibited antibacterial, antimalarial, anti-inflammatory, anthelmintic and antioxidant properties from the stem bark and root of Uapaca guineensis. The air-dried and pulverized stem bark and root of U. guineensis (0.5 kg each) were separately extracted with aqueous ethanol (80%) for 72 hour at room temperature, filtered, concentrated on rotatory evaporator at 37 oC and then stored in a desiccator. The ethanol extracts of the stem bark was partitioned successively with n-hexane, dichloromethane and methanol, while ethanol extract of the root was chromatographed directly. The dichloromethane and methanol extracts of the stem bark was also chromatographed. These results in the formation of whitish powder that are UV inactive and also gave single spot each with cerium sulphate. They are coded as DBG-D13 (25.0 mg), MBG-Q3 (6.1 mg) and ERG-E7 (20.0 mg) for dichloromethane, Methanol and Ethanol extracts respectively. The structure was unequivocally established by 1HNMR, 13CNMR, 2D-NMR, IR, UV and MS spectra analysis as well as by comparison of the spectra data with previously reported values. The dichloromethane, methanol and the ethanol extracts all yielded betulinic acid in substantial quantity. The isolated compound is a confirmation to existing information and an addition to the library of organic compounds.

scholarly journals Arabic Langauge Influences in Southeast Asia: The Case Study of The Maranaos In The Philippines

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Sohayle M. Hadji Abdul Racman ◽  
Reem Lulu
Keyword(s):  
Southeast Asia ◽  
Political Influence ◽  
Arabic Language ◽  
The Philippines ◽  
Related Literature

The Maranaos predominantly inhabit Lanao del Sur in Mindanao in the Southern part of the Philippines. It is observed from the related literature that the Maranao language has numerous Arabic words. However, these Arabic words were not identified in the Maranao language, for this reason, this research focuses on identifying the Arabic words that are used by the Maranaos in their communication. The main objective of this study is to investigate the Arabic vocabulary utilized in Maranao language. The methods used in this research is that the native Maranao and native Arab examined the Arabic words in a Maranao dictionary. The findings revealed that there are over 600 Arabic words used by the Maranaos which is explained as a socio-political influence of the coming of Arabs in the Philippines in the 7th century and onward centuries. Keywords: Arabs; Maranaos; the Philippines; Arabic language; Maranao language

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