Pisonia grandis is a traditional medicinal plant. It is commonly known as Leeachai kottai keerai. The present investigation
focus on screening of phytochemical constituents, antioxidant activity and FT-IR analysis of Pisonia grandis leaf extracts.
The leaf extracts were prepared using three different solvents (Aqueous, Methanol, Ethanol). The antioxidant potential of
the extracts was assessed by employing different assays such as DDPH and ABTS. The screening tests also were performed
for the presence of secondary metabolites such as alkaloids, flavonoids, terpenoids, phenols, steroids, saponins and tannins
in the extracts. The results of FT-IR analysis confirmed the presence of alcohols, alkenes, Phenols, aromatic carboxylic
acid, esters, aliphatic amines, and primary secondary amines in the ethanolic extract. It is concluded that the ethanolic
extract of leaves of Pisonia grandis has potential bioactive compounds. The results of the present study suggest that the
leaves of Pisonia grandis may be used as a herbal alternative to cure various diseases after various scientific validation
studies