Abstract
Objective: To determine whether interleukin 1β (IL-1β) levels are elevated around microscrew implants that are used as anchorage for tooth movement.
Materials and Methods: Ten young adults, aged 16.3 ± 2.5 years and with all four premolars extracted , comprised the study group. Twenty maxillary microscrew implants were placed bilaterally in the alveolar bone between the maxillary second premolars and first molars as anchorage units for distal movement of the maxillary canines. The maxillary canines served as the treatment group, and the microscrew implants were designated as the implant group. The mandibular canines were used as controls. Peri-microscrew implant crevicular fluid (MICF) and gingival crevicular fluid (GCF) were collected at the beginning of tooth movement (2 weeks after implant placement); at 24, 48, and 168 hours later; and on days 14 and 21. An automated enzyme immunoassay was used to measure 1L-1β in the MICF and the GCF.
Results: The mean 1L-1β level in the treatment group was significantly elevated at 24 hours (P = .003 < .05) and 48 hours (P = .003 < .05), whereas the levels in the control and implant groups did not change significantly during the experimental period. Also, the mean 1L-1β level of the treatment group was significantly higher that in both the control and implant groups at 24 and 48 hours.
Conclusions: The microscrew implants did not demonstrate increased 1L-1β levels during tooth movement. This supports the concept that microscrew implants might be useful as absolute anchorage devices.
Influence of smoking on gingival crevicular fluid interleukin 1β and interleukin-8 in patients with severe chronic periodontitis among a Rural Population in India
