Experimental characterization and computational modelling of the effect of in vitro corrosion on the mechanical integrity of biodegradable magnesium alloy WE43 for orthopedic applications

2021 ◽  
Author(s):  
Felipe Saconi ◽  
Anish Roy ◽  
Marcelo Leite Ribeiro
Keyword(s):  
Magnesium Alloy ◽  
Computational Modelling ◽  
Experimental Characterization ◽  
Mechanical Integrity ◽  
Alloy We43 ◽  
Biodegradable Magnesium ◽  
Orthopedic Applications

Cytotoxicity of biodegradable magnesium alloy WE43 to tumor cells in vitro: Bioresorbable implants with antitumor activity?

2019 ◽  
Vol 108 (1) ◽  
pp. 167-173 ◽  
Author(s):  
Natalia Anisimova ◽  
Mikhail Kiselevskiy ◽  
Natalia Martynenko ◽  
Boris Straumal ◽  
Regine Willumeit‐Römer ◽  
...  
Keyword(s):  
Magnesium Alloy ◽  
Antitumor Activity ◽  
Tumor Cells ◽  
Alloy We43 ◽  
Bioresorbable Implants ◽  
Biodegradable Magnesium

scholarly journals Assessment of Galvanostatic Anodic Polarization to Accelerate the Corrosion of the Bioresorbable Magnesium Alloy WE43

2021 ◽  
Vol 11 (5) ◽  
pp. 2128
Author(s):  
Nils Wegner ◽  
Frank Walther
Keyword(s):  
Magnesium Alloy ◽  
Corrosion Rate ◽  
Dissolution Rate ◽  
Anodic Polarization ◽  
Technical Application ◽  
Efficient Manner ◽  
Corrosion Morphology ◽  
Application Range ◽  
Alloy We43

In the field of surgery, bioresorbable magnesium is considered a promising candidate. Its low corrosion resistance, which is disadvantageous for technical application, is advantageous for surgery since the implant fully degrades in the presence of the water-based body fluids, and after a defined time the regenerating bone takes over its function again. Therefore, knowledge of the corrosion behavior over several months is essential. For this reason, an in vitro short-time testing method is developed to accelerate the corrosion progress by galvanostatic anodic polarization without influencing the macroscopic corrosion morphology. The initial corrosion rate of the magnesium alloy WE43 is calculated by detection of the hydrogen volume produced in an immersion test. In a corresponding experimental setup, a galvanostatic anodic polarization is applied with a three-electrode system. The application range for the polarization is determined based on the corrosion current density from potentiodynamic polarization. To correlate the initial corrosion rate, and accelerated dissolution rate, the corrosion morphologies of both test strategies are characterized by microscopy images, as well as energy dispersive X-ray spectroscopy and Fourier-transform infrared spectroscopy. The results demonstrate that the dissolution rate can be increased in the order of decades with the limitation of a changed corrosion morphology with increasing polarization. With this approach, it is possible to characterize and exclude new unsuitable magnesium alloys in a time-efficient manner before they are used in subsequent preclinical studies.

Features of in vitro and in vivo behaviour of magnesium alloy WE43

2018 ◽  
Vol 215 ◽  
pp. 308-311 ◽  
Author(s):  
Elena Lukyanova ◽  
Natalia Anisimova ◽  
Natalia Martynenko ◽  
Mikhail Kiselevsky ◽  
Sergey Dobatkin ◽  
...  
Keyword(s):  
Magnesium Alloy ◽  
Alloy We43

scholarly journals In vitro evaluation of the ZX11 magnesium alloy as potential bone plate: Degradability and mechanical integrity

2019 ◽  
Vol 97 ◽  
pp. 608-622 ◽  
Author(s):  
Ruiqing Hou ◽  
Jose Victoria-Hernandez ◽  
Pingli Jiang ◽  
Regine Willumeit-Römer ◽  
Bérengère Luthringer-Feyerabend ◽  
...  
Keyword(s):  
Magnesium Alloy ◽  
Bone Plate ◽  
In Vitro Evaluation ◽  
Mechanical Integrity

In vitro degradation behavior and cytocompatibility of a bioceramic anodization films on the biodegradable magnesium alloy

2016 ◽  
Vol 488 ◽  
pp. 82-92 ◽  
Author(s):  
Hamouda M. Mousa ◽  
Kamal H. Hussein ◽  
Hem Raj Pant ◽  
Heung M. Woo ◽  
Chan Hee Park ◽  
...  
Keyword(s):  
Magnesium Alloy ◽  
Degradation Behavior ◽  
In Vitro Degradation ◽  
Biodegradable Magnesium

Surface microstructure and in vitro analysis of nanostructured akermanite (Ca2MgSi2O7) coating on biodegradable magnesium alloy for biomedical applications

2014 ◽  
Vol 117 ◽  
pp. 432-440 ◽  
Author(s):  
Mehdi Razavi ◽  
Mohammadhossein Fathi ◽  
Omid Savabi ◽  
Batoul Hashemi Beni ◽  
Daryoosh Vashaee ◽  
...  
Keyword(s):  
Magnesium Alloy ◽  
Biomedical Applications ◽  
Surface Microstructure ◽  
Vitro Analysis ◽  
Biodegradable Magnesium ◽  
In Vitro Analysis
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