scholarly journals Critical Analysis of the Composition Techniques and Devices Used in Troy Roberts' Album 'The XenDen Suite'

2021 ◽  
Author(s):  
◽  
Michael Victor Crawford
Keyword(s):  
Critical Analysis ◽  
Academic Research ◽  
Direct Application ◽  
Body Of Knowledge ◽  
New Information ◽  
Musical Concepts ◽  
Musical Characteristics ◽  
The Many ◽  
And Function ◽  
Insight Into

<p>Troy Roberts is a jazz saxophonist, originally from Perth, West Australia. At present, no academic research has been done on Roberts’ compositions or playing, making this research project a positive way of contributing new information to the academic body of knowledge.   His album, ‘The Xen-Den Suite’ was chosen as the material best suited to provide insight into Roberts’ musicianship (particularly focussing on his compositional and arranging techniques), as it is both intellectually complex and also musically innovative. The aim of the study was to identify and describe the use of various techniques and devices (including their relevance, purpose and function) present in Roberts’ music. Through this study, this researcher attempted to gain a basic overview of Roberts’ musical characteristics, with the objective to be able to utilise this information to further this researcher’s musical development (including compositions, arrangements and saxophone playing).  The findings were useful for direct application (i.e. the techniques could be used in the same manner as they appeared in the XenDen Suite, and could therefore be immediately applied to other areas such as composition, arrangement and improvisation), but the many different ways in which the techniques were used compositionally by Roberts provided a more insightful look into broader musical concepts, and their application.</p>

scholarly journals Critical Analysis of the Composition Techniques and Devices Used in Troy Roberts' Album 'The XenDen Suite'

2021 ◽  
Author(s):  
◽  
Michael Victor Crawford
Keyword(s):  
Critical Analysis ◽  
Academic Research ◽  
Direct Application ◽  
Body Of Knowledge ◽  
New Information ◽  
Musical Concepts ◽  
Musical Characteristics ◽  
The Many ◽  
And Function ◽  
Insight Into

<p>Troy Roberts is a jazz saxophonist, originally from Perth, West Australia. At present, no academic research has been done on Roberts’ compositions or playing, making this research project a positive way of contributing new information to the academic body of knowledge.   His album, ‘The Xen-Den Suite’ was chosen as the material best suited to provide insight into Roberts’ musicianship (particularly focussing on his compositional and arranging techniques), as it is both intellectually complex and also musically innovative. The aim of the study was to identify and describe the use of various techniques and devices (including their relevance, purpose and function) present in Roberts’ music. Through this study, this researcher attempted to gain a basic overview of Roberts’ musical characteristics, with the objective to be able to utilise this information to further this researcher’s musical development (including compositions, arrangements and saxophone playing).  The findings were useful for direct application (i.e. the techniques could be used in the same manner as they appeared in the XenDen Suite, and could therefore be immediately applied to other areas such as composition, arrangement and improvisation), but the many different ways in which the techniques were used compositionally by Roberts provided a more insightful look into broader musical concepts, and their application.</p>

scholarly journals Meta-Research: Citation needed? Wikipedia and the COVID-19 pandemic

2021 ◽  
Author(s):  
Omer Benjakob ◽  
Rona Aviram ◽  
Jonathan Sobel
Keyword(s):  
Vaccine Development ◽  
Academic Research ◽  
Popular Media ◽  
New Information ◽  
Depth Analysis ◽  
Frame Work ◽  
Key Topics ◽  
Digital Knowledge ◽  
Scientific Infrastructure ◽  
Insight Into

With the COVID-19 pandemic’s outbreak at the beginning of 2020, millions across the world flocked to Wikipedia to read about the virus. Our study offers an in-depth analysis of the scientific backbone supporting Wikipedia’s COVID-19 articles. Using references as a readout, we asked which sources informed Wikipedia’s growing pool of COVID-19-related articles during the pandemic’s first wave (January-May 2020). We found that coronavirus-related articles referenced trusted media sources and cited high-quality academic research. Moreover, despite a surge in preprints, Wikipedia’s COVID-19 articles had a clear preference for open-access studies published in respected journals and made little use of non-peer-reviewed research up-loaded independently to academic servers. Building a timeline of COVID-19 articles on Wikipedia from 2001-2020 revealed a nuanced trade-off between quality and timeliness, with a growth in COVID-19 article creation and citations, from both academic research and popular media. It further revealed how preexisting articles on key topics related to the virus created a frame-work on Wikipedia for integrating new knowledge. This “scientific infrastructure” helped provide context, and regulated the influx of new information into Wikipedia. Lastly, we constructed a network of DOI-Wikipedia articles, which showed the landscape of pandemic-related knowledge on Wikipedia and revealed how citations create a web of scientific knowledge to support coverage of scientific topics like COVID-19 vaccine development. Understanding how scientific research interacts with the digital knowledge-sphere during the pandemic provides insight into how Wikipedia can facilitate access to science. It also sheds light on how Wikipedia successfully fended of disinformation on the COVID-19 and may provide insight into how its unique model may be deployed in other contexts.

scholarly journals An Insight into Risk Identification, Quality and Productivity Enhancement using Six Sigma

2011 ◽  
Vol 2 (1) ◽  
pp. 24-33 ◽  
Author(s):  
Muhammad Usman Tariq
Keyword(s):  
Six Sigma ◽  
Critical Analysis ◽  
Business Processes ◽  
Academic Research ◽  
High Standard ◽  
Fortune 500 ◽  
Risk Identification ◽  
Fortune 500 Companies ◽  
Significant Performance ◽  
Insight Into

Six Sigma, with a myriad of its applications in numerous organizational and business processes, offers a project management methodology that supports achieving a goal of near perfection in process performance. Six Sigma is based on the impetus of Plan-Do-Check-Act can help industries, businesses and organizations to achieve significant performance improvement as most of the Fortune 500 companies have adopted Six Sigma (DeFeo & William, 2004). Six Sigma initiatives primarily entail DMAIC and DMADV methods for attaining a high standard of quality. In this paper we provide a critical analysis of the various Six Sigma applications, techniques and tools that can be used for improving quality and productivity of the organizations. The study also provides an insight into the methods used for risk identification in Six Sigma. The proposed techniques are evaluated and analyzed viz-a-viz DMAIC and DMADV approaches. The objective of this research is to summarize the existing level of research in the field of Six Sigma and highlighting the need for intensive academic research in this area. The study comparatively analyzes Six Sigma with Lean, QFD, PSP/TSP, FMEA, TPRM, AHP/ISS and PMBOK requirements. The study also highlights the prospective areas of future/further research in this discipline. The critical analysis of various techniques studied as part of this research reveals that Six Sigma is primarily beneficial for process improvement, risk identification and management etc. The critical analysis of this study is reported herein.

Structure and function of neural networks in the retina

1988 ◽  
Vol 46 ◽  
pp. 26-27
Author(s):  
Peter Sterling
Keyword(s):  
Ganglion Cells ◽  
Three Dimensional ◽  
Structure And Function ◽  
Synaptic Connections ◽  
Visual Axis ◽  
One Dimensional ◽  
Cat Retina ◽  
Ultrathin Sections ◽  
And Function ◽  
Insight Into

The synaptic connections in cat retina that link photoreceptors to ganglion cells have been analyzed quantitatively. Our approach has been to prepare serial, ultrathin sections and photograph en montage at low magnification (˜2000X) in the electron microscope. Six series, 100-300 sections long, have been prepared over the last decade. They derive from different cats but always from the same region of retina, about one degree from the center of the visual axis. The material has been analyzed by reconstructing adjacent neurons in each array and then identifying systematically the synaptic connections between arrays. Most reconstructions were done manually by tracing the outlines of processes in successive sections onto acetate sheets aligned on a cartoonist's jig. The tracings were then digitized, stacked by computer, and printed with the hidden lines removed. The results have provided rather than the usual one-dimensional account of pathways, a three-dimensional account of circuits. From this has emerged insight into the functional architecture.

Intimacy as Transgression and the Problem of Freedom

2018 ◽  
Vol 1 (1) ◽  
pp. 18
Author(s):  
Kym Maclaren
Keyword(s):  
Intimate Relationships ◽  
Critical Analysis ◽  
Mutual Recognition ◽  
Public Institutions ◽  
The Other ◽  
Social Forces ◽  
Critical Insight ◽  
Insight Into ◽  
What Matters

“To consent to love or be loved,” said Merleau-Ponty, “is to consent also to influence someone else, to decide to a certain extent on behalf of the other.” This essay explicates that idea through a meditation on intimacy. I propose, first, that, on Merleau-Ponty’s account, we are always transgressing into each other’s experience, whether we are strangers or familiars; I call this “ontological intimacy.” Concrete experiences of intimacy are based upon this ontological intimacy, and can take place at two levels: (1) at-this-moment (such that we can experience intimacy even with strangers, by sharing a momentary but extra-ordinary mutual recognition) and (2) in shared interpersonal institutions, or habitual, enduring, and co-enacted visions of who we are, how to live, and what matters. Through particular examples of dynamics within these layers of intimacy (drawing upon work by Berne and by Russon), I claim that we are always, inevitably, imposing an “unfreedom” upon our intimate others. Freedom, then, can only develop from within and by virtue of this “unfreedom.” Thus, what distinguishes empowering or emancipating relationships from oppressive ones is not the removal of transgressive normative social forces; it is rather the particular character of those transgressive forces. Some transgressions upon others’ experience—some forms of “unfreedom”—will tend to promote freedom; others will tend to hinder it. This amounts to a call for promoting agency and freedom not only through critical analysis of public institutions, practices and discourses, but also through critical insight into and transformation of our most private and intimate relationships.

Computational Approaches to Predict the Non-canonical DNAs

2019 ◽  
Vol 14 (6) ◽  
pp. 470-479 ◽  
Author(s):  
Nazia Parveen ◽  
Amen Shamim ◽  
Seunghee Cho ◽  
Kyeong Kyu Kim
Keyword(s):  
Computational Methods ◽  
Genetic Instability ◽  
Computational Prediction ◽  
Structure And Function ◽  
Sequence Motifs ◽  
Computational Approaches ◽  
Functional Roles ◽  
And Function ◽  
Genetic Events ◽  
Insight Into

Background: Although most nucleotides in the genome form canonical double-stranded B-DNA, many repeated sequences transiently present as non-canonical conformations (non-B DNA) such as triplexes, quadruplexes, Z-DNA, cruciforms, and slipped/hairpins. Those noncanonical DNAs (ncDNAs) are not only associated with many genetic events such as replication, transcription, and recombination, but are also related to the genetic instability that results in the predisposition to disease. Due to the crucial roles of ncDNAs in cellular and genetic functions, various computational methods have been implemented to predict sequence motifs that generate ncDNA. Objective: Here, we review strategies for the identification of ncDNA motifs across the whole genome, which is necessary for further understanding and investigation of the structure and function of ncDNAs. Conclusion: There is a great demand for computational prediction of non-canonical DNAs that play key functional roles in gene expression and genome biology. In this study, we review the currently available computational methods for predicting the non-canonical DNAs in the genome. Current studies not only provide an insight into the computational methods for predicting the secondary structures of DNA but also increase our understanding of the roles of non-canonical DNA in the genome.

scholarly journals Changing landscapes: Gay men in the west and northwest of Ireland

Sexualities ◽  
2020 ◽  
pp. 136346072098169
Author(s):  
Aidan McKearney
Keyword(s):  
Gay Men ◽  
Social Rights ◽  
Irish Society ◽  
Recent Past ◽  
Same Sex ◽  
Lgbt People ◽  
The Many ◽  
Northwest Region ◽  
The Impact ◽  
Insight Into

This article focuses on the experiences of gay men in the rural west and northwest region of Ireland, during a period of transformational social and political change in Irish society. These changes have helped facilitate new forms of LGBTQI visibility, and local radicalism in the region. Same-sex weddings, establishment of rural LGBT groups and marching under an LGBT banner at St Patricks Day parades would have been unthinkable in the recent past; but they are now becoming a reality. The men report continuing challenges in their lives as gay men in the nonmetropolitan space, but the emergence of new visibility, voice and cultural acceptance of LGBT people is helping change their lived experiences. The study demonstrates the impact of local activist LGBT citizens. Through their testimonies we can gain an insight into the many, varied and interwoven factors that have interplayed to create the conditions necessary for the men to: increasingly define themselves as gay to greater numbers of people in their localities; to embrace greater visibility and eschew strategies of silence; and aspire to a host of legal, political, cultural and social rights including same-sex marriage. Organic forms of visibility and local radicalism have emerged in the region and through an analysis of their testimonies we can see how the men continue to be transformed by an ever-changing landscape.

scholarly journals Significance of Mast Cell Formed Extracellular Traps in Microbial Defense

2021 ◽  
Author(s):  
Daniel Elieh Ali Komi ◽  
Wolfgang M. Kuebler
Keyword(s):  
State Of The Art ◽  
Extracellular Dna ◽  
Cellular Mechanisms ◽  
Extracellular Traps ◽  
Synthetic Chemicals ◽  
Dna Strands ◽  
Associated Proteins ◽  
Microbial Defense ◽  
And Function ◽  
Insight Into

AbstractMast cells (MCs) are critically involved in microbial defense by releasing antimicrobial peptides (such as cathelicidin LL-37 and defensins) and phagocytosis of microbes. In past years, it has become evident that in addition MCs may eliminate invading pathogens by ejection of web-like structures of DNA strands embedded with proteins known together as extracellular traps (ETs). Upon stimulation of resting MCs with various microorganisms, their products (including superantigens and toxins), or synthetic chemicals, MCs become activated and enter into a multistage process that includes disintegration of the nuclear membrane, release of chromatin into the cytoplasm, adhesion of cytoplasmic granules on the emerging DNA web, and ejection of the complex into the extracellular space. This so-called ETosis is often associated with cell death of the producing MC, and the type of stimulus potentially determines the ratio of surviving vs. killed MCs. Comparison of different microorganisms with specific elimination characteristics such as S pyogenes (eliminated by MCs only through extracellular mechanisms), S aureus (removed by phagocytosis), fungi, and parasites has revealed important aspects of MC extracellular trap (MCET) biology. Molecular studies identified that the formation of MCET depends on NADPH oxidase-generated reactive oxygen species (ROS). In this review, we summarize the present state-of-the-art on the biological relevance of MCETosis, and its underlying molecular and cellular mechanisms. We also provide an overview over the techniques used to study the structure and function of MCETs, including electron microscopy and fluorescence microscopy using specific monoclonal antibodies (mAbs) to detect MCET-associated proteins such as tryptase and histones, and cell-impermeant DNA dyes for labeling of extracellular DNA. Comparing the type and biofunction of further MCET decorating proteins with ETs produced by other immune cells may help provide a better insight into MCET biology in the pathogenesis of autoimmune and inflammatory disorders as well as microbial defense.

scholarly journals Spanning the gap: unraveling RSC dynamics in vivo

2021 ◽  
Author(s):  
Heinz Neumann ◽  
Bryan J. Wilkins
Keyword(s):  
Cell Cycle ◽  
Posttranslational Modifications ◽  
Transcriptional Activation ◽  
Binding Mode ◽  
Binding Modes ◽  
Binding Domains ◽  
Binding Interface ◽  
The Many ◽  
And Function

AbstractMultiple reports over the past 2 years have provided the first complete structural analyses for the essential yeast chromatin remodeler, RSC, providing elaborate molecular details for its engagement with the nucleosome. However, there still remain gaps in resolution, particularly within the many RSC subunits that harbor histone binding domains.Solving contacts at these interfaces is crucial because they are regulated by posttranslational modifications that control remodeler binding modes and function. Modifications are dynamic in nature often corresponding to transcriptional activation states and cell cycle stage, highlighting not only a need for enriched spatial resolution but also temporal understanding of remodeler engagement with the nucleosome. Our recent work sheds light on some of those gaps by exploring the binding interface between the RSC catalytic motor protein, Sth1, and the nucleosome, in the living nucleus. Using genetically encoded photo-activatable amino acids incorporated into histones of living yeast we are able to monitor the nucleosomal binding of RSC, emphasizing the regulatory roles of histone modifications in a spatiotemporal manner. We observe that RSC prefers to bind H2B SUMOylated nucleosomes in vivo and interacts with neighboring nucleosomes via H3K14ac. Additionally, we establish that RSC is constitutively bound to the nucleosome and is not ejected during mitotic chromatin compaction but alters its binding mode as it progresses through the cell cycle. Our data offer a renewed perspective on RSC mechanics under true physiological conditions.

Small rodent communities (Muridae) in Gabonese savannas: species diversity and biogeographical affinities

Mammalia ◽  
2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Jean-François Mboumba ◽  
Maxime R. Hervé ◽  
Véronique Guyot ◽  
Frederic Ysnel
Keyword(s):  
Ecological Factors ◽  
Abundant Species ◽  
Small Rodent ◽  
Small Rodents ◽  
South West ◽  
New Information ◽  
Different Types ◽  
Mus Minutoides ◽  
Insight Into ◽  
Coastal Basin

Abstract The study contributes to the knowledge of species composition and biogeographical affinities of savannas rodent in Gabon. Unlike small rodents in Gabonese forests, there is little data on the diversity of small rodents in Gabonese savannas. The diversity and distribution of rodent murid communities was studied in four different types of savanna in Gabon: Coastal Basin (South-West), Lopé/Okanda (in the Center), Batéké Plateaux (Southeastern) and Ngougnié/ N’yanga (in the South). A total of 428 individuals representing six species were captured over 11,920 trap nights. Trap success was highly variable (2.2–6.9 %). The most abundant species were Mus minutoides (69%) followed by Lemniscomys striatus (21.5%). Indices of species richness varied from 2 to 5 and diversity (Shannon and Weaver) was low in the four savannas with the highest value at Ngougnié/N’yanga (H′ = 1.2). Species distributions show that Gabonese savanna small rodents conform to four distribution types, with one species known from Zambesian savannas exhibiting austral affinities (Pelomys campanae: occurs in three southern savannas). This new information provides important insight into the biogeography of small rodents at a local and regional level. Moreover, the correspondence analysis highlighted an influence of local ecological factors on population abundance.

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