scholarly journals Application of Traditional Chinese Medicine Combined with TACE in Patients with Primary Hepatocellular Carcinoma and Its Effect on Liver Function

1970 ◽  
Vol 1 (2) ◽  
Author(s):  
Haibin Ding

Objective: To analyze the effects of Chinese herbal medicine combined with transcatheter arterial chemoembolization (TACE) on liver function in patients with primary hepatocellularCarcinoma (HCC). Methods: 122 patients with primary hepatocellular carcinoma admitted in our hospital from March 2014 to October 2016 were divided into experimental group and control group according to the digital table. The number of each group was the same. The patients in the control group were treated by transcatheter arterial chemoembolization. The experimental group was treated with traditional Chinese medicine on the basis of the control group. SPSS20.0 statistical software for statistical analysis of two groups of patients with short-term effect, follow-up of one year primary liver cancer recurrence rate, before and after treatment WBC count, liver function (alanine aminotransferase), alpha-fetoprotein and Karnofsky index parameters. Results: ①The total effective rate of the experimental group was significantly higher than that of the control group (P <0.05); ②The relapse rate of theexperimental group was significantly lower than that of the control group (P <0.05); ③ Before the treatment, the patients in the two groups had significantly higher recurrence rate than those in the control group (P <0.05). After treatment, the white blood cell count, liver function and alpha-fetoprotein levels in the experimental group were significantly better than those in thecontrol group (P <0.05), but no significant difference was found between the two groups (P<0.05). ④ The Karnofsky score of the experimental group was significantly higher than that of the control group (P<0.05). Conclusion: Chinese medicine combined with transcatheter arterial chemoembolization in patients with primary liver cancer in the application value is relatively high.

2019 ◽  
Author(s):  
Daisuke Yasui ◽  
Aya Yamane ◽  
Hiroshi Itoh ◽  
Masayuki Kobayashi ◽  
Shin-ichiro Kumita

AbstractTranscatheter arterial chemoembolization (TACE) is a standard treatment for unresectable hepatocellular carcinoma; however, it does not always result in tumor control. Nevertheless, treatment outcome can be improved with monodisperse emulsions of anticancer agents. In this study, the efficacy and safety of a monodisperse miriplatin-Lipiodol emulsion were evaluated in Japanese white rabbits. VX2 tumor was implanted into the left liver lobe of each rabbit. The animals were divided into control and experimental groups (of five animals each) and respectively administered a conventional miriplatin suspension or the emulsion via the left hepatic artery. Computed tomography (CT) was performed before, immediately after, and two days following TACE. All rabbits were sacrificed two days after the procedure. Each tumor was removed and cut in half for assessment of iodine concentration in one half by mass spectroscopy and evaluation of Lipiodol accumulation and adverse events in the other half. Mean Hounsfield unit (HU) values were measured using plain CT images taken before and after TACE. Iodine concentration was higher in the experimental group [1100 (750–1500) ppm] than in the control group [840 (660–1800) ppm]. Additionally, the HU value for the experimental group was higher than that for the control group immediately after [199.6 (134.0– 301.7) vs. 165.3 (131.4–280.5)] and two days after [114.2 (56.1–229.8) vs. 58.3 (42.9–132.5)] TACE. Cholecystitis was observed in one rabbit in the control group. Ischemic bile duct injury was not observed in any group. The results show that Lipiodol accumulation and retention in VX2 tumor may be improved by using a monodisperse emulsion. Moreover, no significant adverse events are associated with the use of the emulsion.


2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Yu Zhu ◽  
Lu Shi

Objective: To analyze the clinical treatment effect of traditional Chinese medicine five-color therapy on chronic urticaria in children. Methods: The income data target of this article is 80 children with chronic urticaria. The grouping method is a randomized method with 40 children in each group. The experimental group was treated with five-color treatment of traditional Chinese medicine, and the control group was treated with western medicine. The incidence, treatment and recurrence of adverse reactions in children with chronic urticaria were compared between the two groups. Results: Showed total effective rate of children with chronic urticaria in the experimental group was compared with the control group, P<0.05, the data showed statistical significance. Conclusion: Stated use of TCM five-color therapy in the treatment of children with chronic urticaria can significantly improve safety.


2019 ◽  
Vol 3 (3) ◽  
Author(s):  
Guoqiang Yang ◽  
Jin Zhang

Objective: To analyze the clinical effect and value of oral administration and external therapy of traditional Chinese medicine for treatment of cervical tuberculous lymphadenopathy. Methods: A total of 56 patients with cervical tuberculous lymphadenopathy admitted to our hospital from January 1 to January 2018 were recruited. By using double-blind method, the patients were divided into control group (n=28) and experimental group (n=28). Control group comprised of patients with conventional anti-tuberculosis treatment, while the experimental group comprised of patients treated with oral administration and external therapy of traditional Chinese medicine. Total effective rate, incidence of complication and level of T lymphocyte subsets were compared between the two groups of cervical tuberculous lymphadenopathy patients. Results: Post-treatment data of total effective rate, complication rate, CD3+, CD4+, CD8+, CD4+/CD8+ of the experimental group were compared with the control group. P<0.05; statistical analysis showed statistical significance. Post-treatment data of CD3+, CD4+, CD8+, CD4+/CD8+ of both control and experimental groups were compared with pre-treatment data. P<0.05; statistical analysis showed statistical significance. Conclusion: Oral administration and external therapy of traditional Chinese medicine possesses significant effect in treatment of cervical tuberculous lymphadenopathy.


2021 ◽  
Vol 27 (7) ◽  
pp. 706-709
Author(s):  
Ma Jin

ABSTRACT Introduction: Traditional Chinese medicine has a very good effect on the treatment of exercise fatigue. However, if it is not handled actively and effectively, it can cause serious adverse effects on the body and lead to many diseases. Objective: To study the effect of TCM diagnosis and treatment on athletes’ exercise-induced muscle fatigue. Methods: The results of the study were analyzed by comparing the experimental data in the experimental group and the control group. Results: A paired t test was conducted on the experimental results of the experimental intervention group and the data of the control group. It was found that regardless of individuals being male or female, the paired t test results of the experimental group and the data of the control group were all P < 0.05, showing significant differences in the paired data. Conclusions: In the experiment, all the treatment methods of traditional Chinese medicine had an obvious effect in the treatment of exercise fatigue, and reduced the recovery time of exercise fatigue at different degrees. Contrastive analysis shows that traditional Chinese medicine is effective in the treatment of exercise fatigue. Level of evidence II; Therapeutic studies - investigation of treatment results.


2012 ◽  
Vol 32 (3) ◽  
pp. 299-307 ◽  
Author(s):  
Mouduo Li ◽  
Cuixia Qiao ◽  
Liping Qin ◽  
Junyong Zhang ◽  
Changquan Ling

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