COMBINED CORRECTION OF THE CONDITION OF PATIENTS WITH ARTERIAL HYPERTENSION AND OBESITY

2020 ◽  
pp. 31-35
Author(s):  
Golovanov S.A. ◽  
Kuznetsov I.A. ◽  
Rasulov M.M.
Keyword(s):  
Posterior Wall ◽  
Biologically Active ◽  
Basic Therapy ◽  
Active Supplement ◽  
Functional Features ◽  
Dimensional Echocardiography ◽  
Stage 1 ◽  
Two Dimensional Echocardiography ◽  
Lipid Spectrum ◽  
Diastolic Functions

Patients from 30 to 50 years old, suffering from arterial hypertonia of stage 1-2 and obesity of 1-2 degree, were exam-ined. Pharmacological correction of cardiovascular disorders and changes in lipid metabolism with the use of dietary supplements "Triastin" against the background of basic therapy of patients with AH and OB with enalapril was car-ried out. In addition to the basic therapy, biologically active supplement Triastin was used in the amount of 2 cap-sules per day for 21 days in 2 cycles for 6 months as an additional hypolipidemic agent. Anthropometric research was carried out using unified methods. Obesity was assessed, as well as the lipid spectrum of the blood. The systolic and diastolic functions of the left ventricle, the size of the aorta, atria and right ventricle, the thickness of the interventric-ular septum in diastole (TMZhPd), the thickness of the posterior wall in diastole (TZSD) were determined using two-dimensional echocardiography. The study revealed a more pronounced and stable decrease in the level of blood pres-sure, lipid profile and side effects of basic therapy, improved myocardial remodeling and its functional features.

scholarly journals CONGENITAL DILATED CARDIOMYOPATHY – A RARE GENETIC CONDITION IN INFANTS

2018 ◽  
Vol 2 (2) ◽  
Author(s):  
Xiaoqing Chen ◽  
Guoping Zhou
Keyword(s):  
Mutational Analysis ◽  
Posterior Wall ◽  
Assisted Ventilation ◽  
Left Ventricular ◽  
Heart Beat ◽  
Low Flow ◽  
Two Dimensional ◽  
X Ray ◽  
Dimensional Echocardiography ◽  
Two Dimensional Echocardiography

A male newborn admitted in the Neonatal Intensive Care Unit due to dyspnea and cyanosis. The babywas intubated due to tachypnea. No murmurs were heard on auscultation.The ultrasound of the fetalheart before birth showed cardiac malformations. Chest X-ray showed : Increased pulmonary vascularmarkings and cardiomegaly. The abdominal X-ray showed normal liver, spleen and intestine.Electrocardiogram showed Sinus rhythm and tachycardia.On the first day after birth, two-dimensional echocardiography demonstrated marked hypertrophy ofboth ventricles (the posterior wall of the left ventricle was 33mm thick).The baby was started on treatment with low flow oxygen support, digoxin and captoril to enhancemyocardial contractility, creatine phosphate for myocardial nutrition , furosemide diuretic to reducedload, enhance feeding, monitor bilirubin, prevent neonatal jaundice, and close attention was paid to thedisease changes. The baby was stable and was discharged from the hospital. After 20days of discharge,the baby was admitted again with complains of shortness of breath and cyanosis after 20 days ofdischarge. The heart beat was low on auscultation with alternating tachycardia and bradycardia, with anoccasional gallop rhythm. The baby was kept on ventilator assisted ventilation with the requiredparameters and necessary investigations were performed.On repeating the two-dimensional echocardiography, the left ventricular posterior wall and the ventricularseptum was increased compared to the previous echocardiography. A mutation on Chromosome 18,c.1921G>A was detected on gene mutational analysis. Recently, some genetic studies have shown thatmutations in chromosomes 1, 11, 14 and 15, and mutations in sarcomere proteins genes are autosomaldominant

scholarly journals Exploitation of Marine-Derived Robust Biological Molecules to Manage Inflammatory Bowel Disease

Marine Drugs ◽  
2021 ◽  
Vol 19 (4) ◽  
pp. 196
Author(s):  
Muhammad Bilal ◽  
Leonardo Vieira Nunes ◽  
Marco Thúlio Saviatto Duarte ◽  
Luiz Fernando Romanholo Ferreira ◽  
Renato Nery Soriano ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bioactive Compounds ◽  
Bowel Disease ◽  
Clinical Translation ◽  
Biologically Active ◽  
Naturally Occurring ◽  
Inflammatory Bowel ◽  
Functional Features ◽  
Biological Entities ◽  
The Impact

Naturally occurring biological entities with extractable and tunable structural and functional characteristics, along with therapeutic attributes, are of supreme interest for strengthening the twenty-first-century biomedical settings. Irrespective of ongoing technological and clinical advancement, traditional medicinal practices to address and manage inflammatory bowel disease (IBD) are inefficient and the effect of the administered therapeutic cues is limited. The reasonable immune response or invasion should also be circumvented for successful clinical translation of engineered cues as highly efficient and robust bioactive entities. In this context, research is underway worldwide, and researchers have redirected or regained their interests in valorizing the naturally occurring biological entities/resources, for example, algal biome so-called “treasure of untouched or underexploited sources”. Algal biome from the marine environment is an immense source of excellence that has also been demonstrated as a source of bioactive compounds with unique chemical, structural, and functional features. Moreover, the molecular modeling and synthesis of new drugs based on marine-derived therapeutic and biological cues can show greater efficacy and specificity for the therapeutics. Herein, an effort has been made to cover the existing literature gap on the exploitation of naturally occurring biological entities/resources to address and efficiently manage IBD. Following a brief background study, a focus was given to design characteristics, performance evaluation of engineered cues, and point-of-care IBD therapeutics of diverse bioactive compounds from the algal biome. Noteworthy potentialities of marine-derived biologically active compounds have also been spotlighted to underlying the impact role of bio-active elements with the related pathways. The current review is also focused on the applied standpoint and clinical translation of marine-derived bioactive compounds. Furthermore, a detailed overview of clinical applications and future perspectives are also given in this review.

Prevalence of valvular regurgitation by Doppler echocardiography in patients with structurally normal hearts by two-dimensional echocardiography

1989 ◽  
Vol 117 (3) ◽  
pp. 636-642 ◽  
Author(s):  
Christopher Y. Choong ◽  
vivian M. Abascal ◽  
Jean Weyman ◽  
Robert A. Levine ◽  
Francesco Gentile ◽  
...  
Keyword(s):  
Doppler Echocardiography ◽  
Valvular Regurgitation ◽  
Two Dimensional ◽  
Dimensional Echocardiography ◽  
Two Dimensional Echocardiography
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