Managing polypharmacy for ageing populations

Keyword(s):  
Author(s):  
Sayan Sarcar ◽  
Cosmin Munteanu ◽  
Neil Charness ◽  
Jussi Jokinen ◽  
Xiangshi Ren ◽  
...  

2011 ◽  
Vol 45 (2) ◽  
pp. 200-207 ◽  
Author(s):  
Deborah J Schofield ◽  
Sarah Meachem ◽  
Catherine West ◽  
Maria Kavallaris ◽  
Emily J Callander

2000 ◽  
Vol 6 (2) ◽  
pp. 55-65 ◽  
Author(s):  
Avan Aihie Sayer ◽  
Cyrus Cooper

Ageing may be simply defined but is yet to be well understood. Research in this area is considered a priority, with the population growing older and increasing disability, morbidity and mortality predicted. There are many theories and ageing has been described from changes at the molecular level to characteristics of ageing populations. However, distinguishing cause from effect has proved problematic largely because the underlying reasons for ageing have not been understood. Progress has now been made and the central role for repair processes is increasingly accepted. A number of approaches to modifying ageing have been explored but the only reliable method to alter the rate remains diet restriction. Instituted after weaning, diet restriction slows ageing in a number of species and has an opposite effect when started in earlier life. There is now preliminary evidence that poor early growth is associated with increased human ageing and this is an important area for future research.


Gerontology ◽  
2013 ◽  
Vol 59 (1) ◽  
pp. 32-39 ◽  
Author(s):  
Renske Huffmeijer ◽  
Marinus H. van IJzendoorn ◽  
Marian J. Bakermans-Kranenburg
Keyword(s):  

Author(s):  
Yesola Kweon ◽  
Kohei Suzuki

Since old-age programmes mitigate life-course risks that are relevant to individuals across socio-economic groups in ageing societies, all parties have a political incentive to support these initiatives. Nevertheless, pre-existing partisan commitments bind the policy instruments that parties use. Cabinet-level analyses of OECD economies demonstrate that left incumbency relies more on public expenditure than right-wing governments. What is more important is that, in the context of large elderly populations, pension coverage is greater under right-leaning governments, while pension replacement rates are higher in left-leaning governments. This shows that party behaviour related to life course-related policies cannot be explained by the conventional pro-expansion versus the pro-retrenchment partisan politics. Rather, a focus on partisan variation in the use of policy instruments is required.


2010 ◽  
Vol 26 (7) ◽  
pp. 1314-1322 ◽  
Author(s):  
Luisa Regina Pessôa ◽  
Marcos Ferasso ◽  
Lilia Maria Vargas ◽  
Alcindo Antonio Ferla

The global trend of ageing populations is present in Brazil. Brazilian society is going through an intensive process of transformation, where young adults are increasingly fewer, thus raising the question of who will take care of the elderly in the 21st Century? There is an urgent need to establish care networks for the elderly, covering primary care, including care with housing (Healthy Housing), as well as to ensure access to secondary and tertiary levels of care, providing early diagnoses and rapid access to treatment. This article reports two Brazilian experiences: the restructuring of a shelter for elderly indigents, with 500 elderly residents in Rio de Janeiro, which involved a broad process of humanization, with strong physical restructuring of the buildings that dated from 1930; and the process of organizing the care referral line for the elderly within the Conceição Hospital Group, in Rio Grande do Sul State, which included a health care complex with diverse health units, encompassing all stages of care: from primary care to the most complex hospital treatment.


2021 ◽  
Vol 10 (2) ◽  
pp. 72-82
Author(s):  
Brian Godman ◽  
Steven Simoens ◽  
Amanj Kurdi ◽  
Gisbert Selke ◽  
John Yfantopoulos ◽  
...  

Introduction/Objectives: Health authorities are facing increasing challenges to the sustainability of their healthcare systems because of the growing expenditures on medicines, including new, high-priced oncology medicines, and changes in disease prevalence in their ageing populations. Medicine prices in European countries are greatly affected by the ability to negotiate reasonable prices. Concerns have been expressed that prices of patented medicines do not fall sufficiently after the introduction of lower-cost generic oncology medicines. The objective of this study was to examine the associations over time in selected European countries between the prices of oral oncology medicines, population size, and gross domestic product (GDP) before and after the introduction of generic versions. Evidence of periodic reassessments of the price, value, and place in treatment of these medicines was also looked for. The goal of this review was to stimulate debate about possible improvements in approaches to reimbursement negotiations. Methodology: Analysis was performed of reimbursed prices of three oral oncology medicines (imatinib, erlotinib and fludarabine) between 2013 and 2017 across Europe. Correlations were explored between GDP, population size, and prices. Findings were compared with previous research regarding prices of generic oral oncology medicines. Results: The prices of imatinib, erlotinib and fludarabine varied among European countries, and there was limited price erosion over time in the absence of generics. There appeared to be no correlation between population size and price, but higher prices of on-patent oral cancer medicines were seen among countries with higher GDP per capita. Conclusion: Limited price erosion for patented medicines contributed to increases in oncology medicine budgets across the region. There was also a concerning lack of evidence re-assessments of the price, value, and place in treatment of patented oncology medicines following the loss of patent protection of standard medicines. The use of such proactive re-assessments in negotiating tactics might positively impact global expenditures for oncology medicines.


Author(s):  
Jason L. Powell

This article forecasts quite dramatic increases in the general population of the globe, which will also be reflected in increasing ageing populations. This paper explores how globalization and its structural economic and social forces throws into flux the policies and practices of individual nation states to address social, economic and political issues for older people focusing on empirical data on pensions and health and social care. The paper will examine specific empirical areas of populational projections across the world before we discuss some of the key challenges and consequences of global ageing for the study of ageing populations. It highlights how empirical research needs to move from being state centred to one of which acknowledges global forces and the impact of populational ageing.


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