scholarly journals Control of EPR effect by tumor-targeted NO donor via endogenous albumin transport system

2018 ◽  
Vol 33 (2) ◽  
pp. 130-138
Author(s):  
Yu Ishima ◽  
Toru Maruyama ◽  
Tatsuhiro Ishida ◽  
Masaki Otagiri
Keyword(s):  
Transport System ◽  
No Donor ◽  
Epr Effect ◽  
Endogenous Albumin

scholarly journals Drug Delivery System for Refractory Cancer Therapy via an Endogenous Albumin Transport System

2020 ◽  
Vol 68 (7) ◽  
pp. 583-588 ◽  
Author(s):  
Yu Ishima ◽  
Toru Maruyama ◽  
Masaki Otagiri ◽  
Tatsuhiro Ishida
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery System ◽  
Transport System ◽  
Delivery System ◽  
Endogenous Albumin

scholarly journals Encapsulation of a nitric oxide donor into a liposome to boost the enhanced permeation and retention (EPR) effect

MedChemComm ◽  
2017 ◽  
Vol 8 (2) ◽  
pp. 415-421 ◽  
Author(s):  
Yu Tahara ◽  
Takuma Yoshikawa ◽  
Hikari Sato ◽  
Yukina Mori ◽  
Md Hosain Zahangir ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Donor ◽  
No Donor ◽  
Pegylated Liposome ◽  
Epr Effect ◽  
Enhanced Permeability And Retention

We propose a method to improve the enhanced permeability and retention (EPR) effect of nanomedicines based on tumor-specific vasodilation using a nitric oxide (NO) donor-containing PEGylated liposome.

On the structural organization of biological pumps and channels

1984 ◽  
Vol 42 ◽  
pp. 138-141
Author(s):  
G. Zampighi ◽  
M. Kreman
Keyword(s):  
Active Transport ◽  
Transport System ◽  
Plasma Membranes ◽  
Transport Proteins ◽  
Molecular Organization ◽  
Passive Transport ◽  
Concentration Gradients ◽  
Cell Functions ◽  
Natural Concentration ◽  
Active Transport System

The plasma membranes of most animal cells contain transport proteins which function to provide passageways for the transported species across essentially impermeable lipid bilayers. The channel is a passive transport system which allows the movement of ions and low molecular weight molecules along their concentration gradients. The pump is an active transport system and can translocate cations against their natural concentration gradients. The actions and interplay of these two kinds of transport proteins control crucial cell functions such as active transport, excitability and cell communication. In this paper, we will describe and compare several features of the molecular organization of pumps and channels. As an example of an active transport system, we will discuss the structure of the sodium and potassium ion-activated triphosphatase [(Na+ +K+)-ATPase] and as an example of a passive transport system, the communicating channel of gap junctions and lens junctions.

The role of Ndufb6 subunit of the electron transport system complex I in the regulation of mitochondrial energy metabolism and insulin sensitivity in C2C12 myotubes

2017 ◽  
Vol 12 (S 01) ◽  
pp. S1-S84
Author(s):  
T Jelenik ◽  
SW Görgens ◽  
N Krako Jakovljevic ◽  
I Rokitta ◽  
NM Lalic ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Energy Metabolism ◽  
Electron Transport ◽  
Transport System ◽  
Complex I ◽  
Electron Transport System ◽  
C2c12 Myotubes ◽  
Mitochondrial Energy Metabolism

Placental uric acid transport system and its impact on fetal development

2018 ◽  
Author(s):  
B Lüscher ◽  
D Surbek ◽  
P Schneider ◽  
M Baumann
Keyword(s):  
Uric Acid ◽  
Transport System ◽  
Fetal Development ◽  
Acid Transport

The air transport system

2008 ◽  
Author(s):  
Mike Hirst
Keyword(s):  
Transport System ◽  
Air Transport
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