scholarly journals Nitrite Toxicity to Danio rerio: Effects of Subchronic Exposure on Fish Growth

2008 ◽  
Vol 77 (3) ◽  
pp. 455-460 ◽  
Author(s):  
E. Voslářová ◽  
V. Pištěková ◽  
Z. Svobodová ◽  
I. Bedáňová
Keyword(s):  
Danio Rerio ◽  
Significant Inhibition ◽  
Fish Growth ◽  
Long Term Effects ◽  
Exponential Relationship ◽  
Subchronic Exposure ◽  
Control Growth ◽  
Nitrite Toxicity ◽  
Fish Weight

The aim of this study was to investigate the long-term effects of subchronic exposure to sublethal levels of nitrite, ranging from 15 to 130 mg l-1 NO2-, on growth in aquarium fish Danio rerio. The juvenile growth test according to OECD 215 was used in the experiments. Fish weight was measured at the beginning of the experiment and then using the same method, fish weight was observed 28 days after fish stocking. Compared to the control, growth suppression was detected from the concentration of 73 mg l-1 NO2- (P < 0.05) and a significant inhibition of fish body growth was shown from 130 mg l-1 NO2- (P < 0.01). An exponential relationship between nitrite concentrations and specific growth rate (R2 = 0.896) was detected.

Long-term effects of a binary mixture of perfluorooctane sulfonate (PFOS) and bisphenol A (BPA) in zebrafish (Danio rerio)

2012 ◽  
Vol 118-119 ◽  
pp. 116-129 ◽  
Author(s):  
Su. Keiter ◽  
L. Baumann ◽  
H. Färber ◽  
H. Holbech ◽  
D. Skutlarek ◽  
...  
Keyword(s):  
Binary Mixture ◽  
Bisphenol A ◽  
Danio Rerio ◽  
Perfluorooctane Sulfonate ◽  
Long Term Effects

scholarly journals Effects of Subchronic Exposure of Diclofenac on Growth, Histopathological Changes, and Oxidative Stress in Zebrafish (Danio rerio)

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Eva Praskova ◽  
Lucie Plhalova ◽  
Lucie Chromcova ◽  
Stanislava Stepanova ◽  
Iveta Bedanova ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Glutathione Reductase ◽  
Danio Rerio ◽  
Fish Growth ◽  
Histopathological Changes ◽  
Glutathione S Transferase ◽  
Environmental Concentration ◽  
Subchronic Exposure ◽  
Effect Concentration ◽  
And Oxidative Stress

The aim of this study was to investigate effects of subchronic exposure to sublethal levels of diclofenac on growth, oxidative stress, and histopathological changes inDanio rerio. The juvenile growth tests were performed onDanio rerioaccording to OECD method number 215. Fish at the age of 20 days were exposed to the diclofenac environmental concentration commonly detected in the Czech rivers (0.02 mg L−1) and the range of sublethal concentrations of diclofenac (5, 15, 30, and 60 mg L−1) for 28 days. A significant decrease (P<0.01) in the fish growth caused by diclofenac was observed in the concentrations of 30 and 60 mg L−1. The identified value of LOEC (lowest observed effect concentration) was 15 mg L−1of diclofenac and NOEC (no observed effect concentration) value was 5 mg L−1of diclofenac. We did not find histopathological changes and changes of selected parameters of oxidative stress (glutathione S-transferase, glutathione reductase) in tested fish. The environmental concentration of diclofenac in Czech rivers did not have any effect on growth, selected oxidative stress parameters (glutathione S-transferase, glutathione reductase), or histopathological changes inDanio reriobut it could have an influence on lipid peroxidation.

scholarly journals Nitrite Toxicity to Danio Rerio: Effects of Fish Age and Chloride Concentrations

2006 ◽  
Vol 75 (1) ◽  
pp. 107-113 ◽  
Author(s):  
E. Voslářová ◽  
V. Pištěková ◽  
Z. Svobodová
Keyword(s):  
Danio Rerio ◽  
Larval Stage ◽  
Developmental Stages ◽  
Juvenile Stage ◽  
Exponential Relationship ◽  
Nitrite Toxicity ◽  
Chloride Concentrations

The aim of the present study was to compare the acute nitrite toxicity for Danio rerio at the age of 20-25 days (larval stage) and 2-3 months (juvenile stage) at various chloride concentrations. The semistatic method according to OECD 203 was used in the tests. The 96hLC50 NO2- value was 386.00 ± 29.75 mg l-1 (D. rerio aged 20-25 days), and 242.41 ± 13.67 mg l-1 (D. rerio aged 2-3 months), respectively, at 19 mg Cl- l-1 in diluting water. We observed an increase in 96hLC50 NO2- in D. rerio of both developmental stages following an increase in Cl- concentration in diluting water. A comparison between the 96hLC50 NO2- determined for D. rerio aged 20-25 days and those aged 2-3 months at different chloride concentrations in diluting water (19; 50; 100 mg l-1) showed a highly significant increase (p < 0.01) in the 96hLC50 NO2- for the younger fish at all chloride concentrations. An exponential relationship between 96hLC50 NO2- values and chloride concentrations in diluting water (I = 0.849) was demonstrated in D. rerio aged 20-25 days while a logarithmical relationship (I = 0.856) was observed in D. rerio aged 2-3 months.

scholarly journals Long-term effects of electromagnetic radiation of the mobile phone frequency on the morphofunctional state of the reproductive system of rats and males and their offspring

2019 ◽  
Vol 63 (2) ◽  
pp. 198-206
Author(s):  
N. V. Chueshova ◽  
F. I. Vismont
Keyword(s):  
Electromagnetic Radiation ◽  
Mobile Phone ◽  
Reproductive System ◽  
Prolonged Exposure ◽  
Significant Inhibition ◽  
Male Rats ◽  
Long Term Effects ◽  
Initial Stage ◽  
Spermatogenic Epithelium

The experiment established the long-term effects of low-intensity electromagnetic radiation from a mobile phone (EMR MP 1745 MHz, xpd = 7.5 ± 0.3 μW/cm2) in the offspring of male rats from parents, one of which was either subjected to a prolonged exposure of the investigated factor. A change in the sex ratio of the born offspring and a decrease in their body weight have been established. The analysis of the reproductive system of the offspring of males when they reached the age of 2 and 4 months, revealed significant impairments, with the most pronounced changes found in the offspring obtained from both the irradiated parents or when only the male was irradiated. These changes are manifested in the disruption of the normal functioning of the spermatogenic epithelium, namely, an intensification of the initial stage of spermatogenesis is noted, with a significant inhibition at the stage of spermatid transformation. A decrease in the number of mature germ cells – spermatozoa and a pronounced deterioration of their viability, as well as an increase in testosterone secretion is established. The revealed violations in the morphofunctional state of the reproductive system of the offspring suggest that the trans-generation effect of EMR exposure generated by cellular sources can be considered as a factor affecting the decline in the male fertility.

Acute and long-term effects after single loading of functionalized multi-walled carbon nanotubes into zebrafish (Danio rerio)

2009 ◽  
Vol 235 (2) ◽  
pp. 216-225 ◽  
Author(s):  
Jinping Cheng ◽  
Chung Man Chan ◽  
L. Monica Veca ◽  
Wing Lin Poon ◽  
Po Kwok Chan ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Danio Rerio ◽  
Long Term Effects ◽  
Multi Walled Carbon Nanotubes ◽  
Walled Carbon Nanotubes

PAH-INDUCED IMPACTS ON THE BIOENERGETICS AND POPULATION DYNAMICS OF FUNDULUS HETEROCLITUS: MODEL APPLICATION FOR ASSESSING LONG-TERM EFFECTS FROM OIL SPILLS1

2005 ◽  
Vol 2005 (1) ◽  
pp. 375-378
Author(s):  
Amy A. Merten ◽  
Eileen B. Beard ◽  
Joel E. Baker
Keyword(s):  
Fundulus Heteroclitus ◽  
Growth Parameters ◽  
Fish Growth ◽  
Estuarine Fish ◽  
Metabolic Rates ◽  
Long Term Effects ◽  
Maintenance Respiration ◽  
Bioenergetic Model ◽  
Model Application

ABSTRACT Long-term residual contamination from oil spills and other sources of organic contaminants may exert sublethal baseline toxicity (narcosis) on fish populations. Low level, chronic exposures to narcotic chemicals such as polycyclic aromatic hydrocarbons (PAHs) may impose a metabolic cost on a fish, changing its allocation of energy available for growing, reproducing, foraging for food, and escaping predation. To examine this hypothesis, naïve Fundulus heteroclitus, a ubiquitous estuarine fish species with a short home range, were exposed to a gradient of PAH concentrations in their diets over 120 days. On days 0, 35, 62, 90, and 120, we measured individual fish growth parameters and standard metabolic rates. Standard metabolic rates increased with increasing PAH load (p = 0.087). Long-term exposure to dietary PAHs altered fish maintenance respiration on individuals. We are developing a bioenergetic model to evaluate whether long-term exposure to PAHs sufficiently impacts individual parameters to the extent that the Fundulus population will be affected. Multiple life stages (e.g., eggs, larvae, juveniles, and adults) and generations will be represented with bioenergetic and bioaccumulative processes altered to mimic impacts measured in the experiment. The narcosis induction submodel subjects cohorts to metabolic alterations by imposing a narcotic gradient from no effect to a level where time to critical body residue shifts, thus changing population mortality probabilities. Each model scenario will be compared and contrasted to quantify PAH effects, and to discuss the importance of cumulative chemical stress to fish. Results from the study and model application will be used to evaluate long-term, population-level consequences of sublethal exposures to narcotic contaminants to improve the basis for risk assessment analyses.

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