scholarly journals Is there room for improving case management for contacts of meningococcal disease in the European Union?

2008 ◽  
Vol 13 (10) ◽  
pp. 1-2 ◽  
Author(s):  
P L Lopalco
Keyword(s):  
European Union ◽  
Meningococcal Disease ◽  
Case Fatality Rate ◽  
Case Fatality ◽  
Severe Illness ◽  
Fatality Rate ◽  
The European Union ◽  
High Case Fatality Rate ◽  
Children And Young Adults ◽  
Loss Of Limbs

Invasive meningococcal disease (IMD) is a severe illness primarily affecting children and young adults. It has a high case fatality rate (10%-14%) and 11%-19% of patients who recover experience permanent hearing loss, mental retardation, loss of limbs or other serious sequelae.

scholarly journals Invasive meningococcal disease associated with a very high case fatality rate in the North-West of Poland

2006 ◽  
Vol 46 (2) ◽  
pp. 230-235 ◽  
Author(s):  
Anna SkoczyÅ„ska ◽  
Marcin KadÅ‚ubowski ◽  
Józef Knap ◽  
Maria Szulc ◽  
Marzena Janusz-Jurczyk ◽  
...  
Keyword(s):  
Meningococcal Disease ◽  
Case Fatality Rate ◽  
Case Fatality ◽  
Invasive Meningococcal Disease ◽  
Fatality Rate ◽  
High Case Fatality Rate ◽  
North West ◽  
The North ◽  
Very High

scholarly journals The European Union faces up to the threat of a pandemic: meeting at the DGV on the influenza A (H5N1) of the ad hoc group on communicable diseases Luxembourg 14 January 1998

1998 ◽  
Vol 3 (3) ◽  
pp. 25-6 ◽  
Author(s):  
J C Desenclos ◽  
R Manigat
Keyword(s):  
Influenza A ◽  
Case Fatality Rate ◽  
H5n1 Virus ◽  
Ad Hoc ◽  
Influenza Pandemic ◽  
Case Fatality ◽  
Fatality Rate ◽  
The European Union ◽  
High Case Fatality Rate ◽  
Influenza H5n1

The transmission of an avian influenza H5N1 virus to a child in Hong Kong in May 1997 followed by the occurrence of 17 other human cases with a high case fatality rate (6/18, 33%) suggested that an influenza pandemic could be imminent and led many Europea

Introduction

2011 ◽  
Vol 21 (Supp 1) ◽  
pp. S1-S2 ◽  
Author(s):  
Andrés Poveda
Keyword(s):  
United States ◽  
Ovarian Cancer ◽  
European Union ◽  
Case Fatality Rate ◽  
Gynecological Cancer ◽  
Case Fatality ◽  
The United States ◽  
Fatality Rate ◽  
The European Union ◽  
Gynecological Malignancies

Ovarian cancer is the second most common gynecological cancer, representing 5% of all cancers in women. It has the highest case-fatality rate of all gynecological malignancies. In the European Union, there are approximately 48,000 new cases of ovarian cancer and 31,000 deaths per year. Similarly, in the United States, there are approximately 25,500 new cases per year, with 16,000 deaths associated.

scholarly journals Variations in case fatality and fatality risk factors of meningococcal disease in Western Norway, 1985–2002

2005 ◽  
Vol 134 (1) ◽  
pp. 103-110 ◽  
Author(s):  
I. SMITH ◽  
A. T. BJØRNEVIK ◽  
I. M. B. AUGLAND ◽  
A. BERSTAD ◽  
T. WENTZEL-LARSEN ◽  
...  
Keyword(s):  
Risk Factors ◽  
Skin Rash ◽  
Meningococcal Disease ◽  
Case Fatality Rate ◽  
Multivariate Analyses ◽  
Case Fatality ◽  
Fatality Rate ◽  
The Public ◽  
Admission Time ◽  
Meningococcal Septicaemia

SUMMARYIn a retrospective epidemiological study, 293 meningococcal disease patients hospitalized during 1985–2002, were examined for fatality and risk factors related to death. The overall case fatality rate (CFR) was 8·2%, but increased from 4% during 1985–1993 to 17% during 1994–2002. The latter 9-year period was characterized by more serogroup C infections and more patients with thrombocytopenia on admission to hospital. All patients categorized as meningitis on admission survived. Of the 24 patients who died, 21 had meningococcal skin rash on admission, 23 had an onset to admission time of ⩽24 h, and 16 had severe septicaemia with hypotension and/or ecchymoses without meningitis on admission. By multivariate analyses, a short onset to admission time, >50 petechiae, thrombocytopenia and severe septicaemia on admission were associated with fatality. More lives could be saved through earlier admission to hospital. This can be achieved through more information to the public about the early signs of meningococcal septicaemia, with the recommendation to look for skin rash in patients with acute fever during the first day and night.

scholarly journals Crimean-Congo hemorrhagic fever-induced liver injury: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Sawai Singh Rathore ◽  
Ade Harrison Manju ◽  
Qingqing Wen ◽  
Manush Sondhi ◽  
Reshma Pydi ◽  
...  
Keyword(s):  
Liver Injury ◽  
Case Fatality Rate ◽  
Meta Analysis ◽  
Case Series ◽  
Case Fatality ◽  
Hemorrhagic Fever ◽  
Fatality Rate ◽  
High Case Fatality Rate ◽  
Crimean Congo Hemorrhagic Fever ◽  
Pooled Prevalence

Background: Crimean-Congo hemorrhagic fever (CCHF) is a fatal acute tick-borne viral infection and a substantial emerging global public health threat. This illness has a high case fatality rate of up to 40%. The liver is one of the important target organs of the CCHF virus. Objective: The aim of this meta-analysis to evaluate the correlation between CCHF  and liver injury and draw more generalized inferences about the abnormal serum markers of liver injury such as alanine aminotransferase (ALT), aspartate aminotransferase (AST) in CCHF patients. Methods: A literature search was accomplished for published eligible articles with MEDLINE/PubMed and Embase databases. All eligible observational studies and case series were included from around the world. The inclusion criteria were articles describing liver injury biomarkers AST and ALT amongst patients diagnosed with CCHF. Results: Data from 18 studies, consisting of 1238 patients with CCHF  were included in this meta-analysis. The overall pooled prevalence of at least one raised liver injury biomarker was 77.95% (95% CI, I2 = 88.50%, p < 0.0001). Similarly, pooled prevalence of elevated AST and ALT was 85.92% (95% CI, I2 = 85.27%,  p < 0.0001) and 64.30% (95% CI, I2 = 88.32%,  p < 0.0001) respectively.  Both Egger and Begg-Mazumdar’s tests detected no apparent publication bias in all three meta-analyses(p > 0.05).  Conclusion: These elevated liver injury biomarkers have been identified as significant prognostic factors. Hence, Physicians must recognize and continuously monitor these biomarkers, since these aid early stratification of prognosis and the prevention of severe outcomes in infection with such a high case fatality rate.

scholarly journals COVID-19 in Sudan

2021 ◽  
Vol 15 (02) ◽  
pp. 204-208
Author(s):  
Ayman Ahmed ◽  
Nouh Saad Mohamed ◽  
Sarah Misbah EL-Sadig ◽  
Lamis Ahmed Fahal ◽  
Ziad Bakri Abelrahim ◽  
...  
Keyword(s):  
Health Systems ◽  
Case Fatality Rate ◽  
Case Fatality ◽  
Control Measures ◽  
Religious Practices ◽  
Mass Gathering ◽  
Fatality Rate ◽  
High Case Fatality Rate ◽  
The Government ◽  
And Control

The steadily growing COVID-19 pandemic is challenging health systems worldwide including Sudan. In Sudan, the first COVID-19 case was reported on 13th March 2020, and up to 11 November 2020 there were 14,401 confirmed cases of which 9,535 cases recovered and the rest 3,750 cases were under treatment. Additionally, 1,116 deaths were reported, indicating a relatively high case fatality rate of 7.7%. Several preventive and control measures were implemented by the government of Sudan and health partners, including the partial lockdown of the country, promoting social distancing, and suspending mass gathering such as festivals and performing religious practices in groups. However, new cases still emerging every day and this could be attributed to the noncompliance of the individuals to the advocated preventive measurements.

Subway-Related Trauma: An Urban Public Health Issue with a High Case-Fatality Rate

2018 ◽  
Vol 55 (2) ◽  
pp. 165-171.e1 ◽  
Author(s):  
Simon G. Rodier ◽  
Charles J. DiMaggio ◽  
Stephen Wall ◽  
Vasiliy Sim ◽  
Spiros G. Frangos ◽  
...  
Keyword(s):  
Public Health ◽  
Case Fatality Rate ◽  
Case Fatality ◽  
Health Issue ◽  
Public Health Issue ◽  
Fatality Rate ◽  
High Case Fatality Rate

scholarly journals Aortic valve endocarditis with Erysipelothrix rhusiopathiae: A rare zoonosis

2018 ◽  
Vol 10 (3) ◽  
Author(s):  
Jenny Jónsdóttir Nielsen ◽  
Bjørn Blomberg ◽  
Shahin Gaïni ◽  
Steinar Lundemoen
Keyword(s):  
Aortic Valve ◽  
Case Fatality Rate ◽  
Case Fatality ◽  
Animal Husbandry ◽  
Skin Infections ◽  
Fatality Rate ◽  
Erysipelothrix Rhusiopathiae ◽  
High Case Fatality Rate ◽  
Exposed Skin ◽  
Spare Time

Erysipelothrix rhusiopathiae has an economic impact in animal husbandry by causing infection in swine, sheep and poultry. E. rhusiopathiae is present in the surface mucoid slime on fish, although fishes do not seem to be affected. Humans can get infected, maost often through occupational exposure and may suffer typical erysipeloid infection on exposed skin such as on hands and fingers, or deeper skin infections, and sometimes sepsis and endocarditis, associated with high case-fatality rate. We describe a case of aortic valve endocarditis caused by E. rhusiopathiae in a 59-year-old man who enjoyed fishing in his spare time.

Neonatal Candida parapsilosis outbreak with a high case fatality rate

1995 ◽  
Vol 14 (9) ◽  
pp. 776-781 ◽  
Author(s):  
HARRI SAXEN ◽  
MARTTI VIRTANEN ◽  
PETTERI CARLSON ◽  
KALLE HOPPU ◽  
MAIJA POHJAVUORI ◽  
...  
Keyword(s):  
Case Fatality Rate ◽  
Candida Parapsilosis ◽  
Case Fatality ◽  
Fatality Rate ◽  
High Case Fatality Rate

scholarly journals Diphtheria in Hull: A Review of six years bacteriological typing

1945 ◽  
Vol 44 (3) ◽  
pp. 184-192
Author(s):  
H. Mason Leete
Keyword(s):  
Case Fatality Rate ◽  
Case Fatality ◽  
Great Majority ◽  
Consecutive Series ◽  
City Hospital ◽  
Fatality Rate ◽  
High Case Fatality Rate ◽  
Clinical Cases

This paper embodies the findings in all proven cases of diphtheria admitted to the Hull City Hospital during the years 1938–43 inclusive. All cases during those 6 years were typed and the clinical and bacteriological findings correlated. Since 1932 all severe cases had been typed and in the winter of 1932–3 a consecutive series of 313 cases was investigated and the results published (Leete, McLeod & Morrison, 1933). The 1933 paper showed a high gravis incidence of 59% and an associated high case fatality rate. Not until the end of 1937 was it again possible to type every case admitted but since then we have done so, and the series now presented embodies observations on 2039 infections, the great majority of which were clinical cases.

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