scholarly journals Nosocomial measles cluster in Denmark following an imported case, December 2008-January 2009

2009 ◽  
Vol 14 (8) ◽  
Author(s):  
C Groth ◽  
B E Böttiger ◽  
A Plesner ◽  
A H Christiansen ◽  
S Glismann ◽  
...  

A cluster of six confirmed cases with identical measles virus genotype was reported in Denmark between December 2008 and January 2009. Transmission occurred among unvaccinated children aged 15-23 months admitted to the same hospital as a 36-month-old unvaccinated girl diagnosed with measles following travel. The findings highlight the importance of vaccination before travelling and adherence to the routine vaccination schedule.

2020 ◽  
pp. 83-88
Author(s):  
Kseniia Artemivna Veklych

Measles is a highly contagious infectious disease caused by an RNA−containing virus of the family Paramyxoviridae and Morbillivirus genus. The most proper way to stop it is a total vaccination. At the moment, live attenuated strains of the Enders − Schwartz measles virus are used to conduct it. Although they were developed more than 50 years ago, the vaccines in use today are effective enough to create a proper immune protection that can defend against an infection for decades, if the vaccination schedule is followed. The vast majority of measles outbreaks that have been reported in Europe over the last seven years have been caused by a lack of an immune response resulting from the unprecedented coverage of the population with vaccination. The measles outbreak observed in the adult and child population of Ukraine since December 2018 indicates the need and urgency of additional efforts to curb the spread and complete elimination of the measles virus. It has been determined that more than 95 % of the population should be vaccinated to ensure an elimination of measles virus and prevent the disease outbreaks after the virus has been imported from the countries that are still endemic to measles. It is noted that as a result of successful implementation of vaccination programs, the public's attention to measles is diminished even among physicians who sometimes have a rather dubious understanding of the disease symptoms. Ensuring a complete elimination of the measles virus requires the development and implementation of additional laboratory tests for immunity, development and realization of new, more polyvalent vaccines that are more readily accepted by population, increased awareness on safety and necessity of vaccination, as well as regulation. Key words: measles, immunity, elimination, epidemiological control, vaccination.


PLoS ONE ◽  
2018 ◽  
Vol 13 (7) ◽  
pp. e0199975 ◽  
Author(s):  
Horacio Gil ◽  
Aurora Fernández-García ◽  
María Mar Mosquera ◽  
Judith M. Hübschen ◽  
Ana M. Castellanos ◽  
...  

2019 ◽  
Vol 8 (29) ◽  
Author(s):  
You-Jin Kim ◽  
Hae Ji Kang ◽  
Su-Jin Kim ◽  
Hye Min Lee ◽  
Sung Soon Kim

The complete genome sequences of three wild-type measles viruses (genotype D8) isolated from patients in South Korea were determined. These are the first reported complete genome sequences of measles viruses obtained from South Korea, and the availability of these sequences will improve our understanding of measles virus transmission and genetic diversity.


2018 ◽  
Vol 24 (6) ◽  
pp. 720-729 ◽  
Author(s):  
K. Pabbaraju ◽  
K. Fonseca ◽  
S. Wong ◽  
M. W. Koch ◽  
J. T. Joseph ◽  
...  

2002 ◽  
Vol 8 (7) ◽  
pp. 735-737 ◽  
Author(s):  
Doris Chibo ◽  
Michaela Riddell ◽  
Michael Catton ◽  
Christopher Birch

2013 ◽  
Vol 55 (4) ◽  
pp. 292-292
Author(s):  
Maria Isabel de Oliveira ◽  
Cristina Adelaide Figueiredo ◽  
Ana Maria Sardinha Afonso ◽  
Marilda Mendonca Siqueira ◽  
Xenia Rawena Medeiros Romeu Lemos ◽  
...  

2012 ◽  
Vol 17 (37) ◽  
Author(s):  
E Kopel ◽  
Z Amitai ◽  
M Savion ◽  
Y Aboudy ◽  
E Mendelson ◽  
...  

A measles outbreak is affecting the Tel Aviv district, Israel, since April 2012. As of 10 September, 99 cases were confirmed, including 63 (64%) migrants of Eritrean and Sudanese origin. All genotyped cases had the African B3 genotype*. The mean age of migrant and non-migrant cases was 6.0±9.6 and 30.2±24.2 years, respectively (p<0.001). The majority of both migrant and non-migrant cases was unvaccinated. This is the second African measles B3 genotype outbreak within the World Health Organization European region in 2012.


2010 ◽  
Vol 16 (6) ◽  
pp. 943-947 ◽  
Author(s):  
Yan Zhang ◽  
Zhengrong Ding ◽  
Huiling Wang ◽  
Liqun Li ◽  
Yankun Pang ◽  
...  
Keyword(s):  

2020 ◽  
Vol 97 (2) ◽  
pp. 182-189
Author(s):  
Georgy M. Ignatyev ◽  
Alena V. Atrasheuskaya ◽  
Lidiya L. Sukhanova ◽  
Elena S. Sidorenko ◽  
Nina A. Netesova

Aim. To study the genetic stability of the measles virus strain Leningrad-16 (L-16) used for the production of vaccine at JSC NPO Mikrogen.Materials and methods. A series of production and sowing strains of L-16 (JSC NPO Mikrogen), ready-made series of measles vaccines from various manufacturers, and the strain of measles virus genotype D6 were studied. Molecular genetic study of the strains was performed using RT-PCR followed by restriction analysis and sequencing.Results. The complete genome sequences of the production and sowing strains of L-16 that are used for vaccine production were obtained. The sequence of the vaccine strain was deposited in GenBank. Strain L-16 was confirmed to be genetically stable. The obtained data demonstrated the possibility of using the RT-PCR method with subsequent restriction analysis to confirm the authenticity of the vaccine strain L-16 in finished mono and three component vaccines.Conclusion. The results of the study suggest the applicability of the molecular genetic methods to confirm the authenticity of the studied strains not only at the production stages, but also in the finished series of vaccines.


Viruses ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 1970
Author(s):  
Nan Zhou ◽  
Mingma Li ◽  
Yue Huang ◽  
Lu Zhou ◽  
Bei Wang

Measles virus (MeV) genotype B3 is one globally significant circulating genotype. Here, we present a systematic description of long-term evolutionary characterizations of the MeV genotype B3’s hemagglutinin (H) gene in the elimination era. Our results show that the B3 H gene can be divided into two main sub-genotypes, and the highest intra-genotypic diversity was observed in 2004. MeV genotype B3’s H gene diverged in 1976; its overall nucleotide substitution rate is estimated to be 5.697 × 10−4 substitutions/site/year, and is slowing down. The amino acid substitution rate of genotype B3’s H gene is also decreasing, and the mean effective population size has been in a downward trend since 2000. Selection pressure analysis only recognized a few sites under positive selection, and the number of positive selection sites is getting smaller. All of these observations may reveal that genotype B3’s H gene is not under strong selection pressure, and is becoming increasingly conservative. MeV H-gene or whole-genome sequencing should be routine, so as to better elucidate the molecular epidemiology of MeV in the future.


Sign in / Sign up

Export Citation Format

Share Document