scholarly journals BSE-related health risks from goat meat: scientific opinion from the European Food Safety Authority

2005 ◽  
Vol 10 (26) ◽  
Author(s):  
Collective Editorial team

The risk of exposure to the bovine spongiform encephalopathy infectious agent from consumption of goat meat by humans is considered to be small, according to the EFSA

Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 2095
Author(s):  
Pedro Estevan Navarro ◽  
Isabel Sospedra ◽  
Alejandro Perales ◽  
Cristina González-Díaz ◽  
Rubén Jiménez-Alfageme ◽  
...  

Caffeine is a food supplement widely consumed by athletes, but it has not been established. So far, the veracity of their labeling in terms of the dosage and cause/effect relationship aimed at the consumer. The aim is to analyze the health claims and the dosage presented on the labeling of caffeine supplements and to evaluate if they follow the European Food Safety Authority (EFSA) and international criteria. A descriptive cross-sectional study of a sample of caffeine supplements was carried out. The search was done through the Amazon and Google Shopping web portals. In order to assess the adequacy of the health claims, the guidelines of reference established by European Food Safety Authority were compared to the Academy of Nutrition and Dietetics, International Olympic Committee, and Australian Institute of Sport guidelines; in addition, recent systematic reviews were addressed. A review of labels of 42 caffeine supplements showed that, in less than 3% of the products were the health claims supported by the recommendations and by the labeled quantity of caffeine. The claims that fully complied the recommendations were, “improves or increases endurance performance”, “improves strength performance”, or “improves short-term performance”. In most cases, the recommended dosage was 200 mg/day for these products, which is the minimum for the caffeine effects to be declared. The rest of the health claims were not adequate or need to be modified. Most of the health claims identified indicated an unproven cause and effect, which constitutes consumer fraud, and so must be modified or eliminated.


1989 ◽  
Vol 18 (4) ◽  
pp. 165-168 ◽  
Author(s):  
W. F. Blakemore

Bovine spongiform encephalopathy (BSE), a recently recognized disease of cattle, resulted from the incorporation of scrapie-infected sheep tissue into cattle food. BSE and scrapie are members of a group of transmissible diseases caused by an unconventional infectious agent, some of which affect man. As these diseases can cross species barriers this new bovine disease may represent a potential disease hazard to man.


Toxins ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 312
Author(s):  
Andrea Boente-Juncal ◽  
Paz Otero ◽  
Inés Rodríguez ◽  
Mercedes Camiña ◽  
Mercedes Rodriguez-Vieytes ◽  
...  

Tetrodotoxin (TTX) is a potent natural toxin causative of human food intoxications that shares its mechanism of action with the paralytic shellfish toxin saxitoxin (STX). Both toxins act as potent blockers of voltage-gated sodium channels. Although human intoxications by TTX were initially described in Japan, nowadays increasing concern about the regulation of this toxin in Europe has emerged due to its detection in fish and mollusks captured in European waters. Currently, TTX is only regularly monitored in Dutch fishery products. However, the European Food Safety Authority (EFSA) has established a safety level of 44 µg/kg TTX as the amount of toxin that did not cause adverse effects in humans. This level was extrapolated considering initial data on its acute oral toxicity and EFSA remarked the need for chronic toxicity studies to further reduce the uncertainty of future toxin regulations. Thus, in this work, we evaluated the oral chronic toxicity of TTX using the safety levels initially recommended by EFSA in order to exclude potential human health risks associated with the worldwide expanding presence of TTX. Using internationally recommended guidelines for the assessment of oral chronic toxicity, the data provided here support the proposed safety level for TTX as low enough to prevent human adverse effects of TTX even after chronic daily exposure to the toxin. However, the combination of TTX with STX at doses above the maximal exposure level of 5.3 µg/kg body weight derived by EFSA increased the lethality of TTX, thus confirming that both TTX and paralytic shellfish toxins should be taken into account to assess human health risks.


2006 ◽  
Vol 75 (3-4) ◽  
pp. 221-238 ◽  
Author(s):  
Takehisa Yamamoto ◽  
Toshiyuki Tsutsui ◽  
Takashi Nonaka ◽  
Sota Kobayashi ◽  
Akiko Nishiguchi ◽  
...  

2005 ◽  
Vol 79 (9) ◽  
pp. 5847-5849 ◽  
Author(s):  
Cristina Casalone ◽  
Cristiano Corona ◽  
Maria Ines Crescio ◽  
Francesca Martucci ◽  
Maria Mazza ◽  
...  

ABSTRACT Tongue involvement by prion spreading was shown to be a common outcome after oral or intracranial experimental challenge with scrapie and transmissible mink encephalopathy sources in rodent models. It is also known that bovine spongiform encephalopathy, which is pathogenic for humans, is experimentally transmissible to sheep and can lead to a disease indistinguishable from scrapie. A recent European Food Safety Authority opinion recommended research into PrPsc accumulation in the tongues of ruminants. We report on the detection of PrPsc in the tongues of seven scrapie-infected sheep by immunohistochemistry and Western blotting.


2014 ◽  
Vol 95 (8) ◽  
pp. 1855-1859 ◽  
Author(s):  
Chris Plinston ◽  
Patricia Hart ◽  
Nora Hunter ◽  
Jean C. Manson ◽  
Rona M. Barron

Bovine spongiform encephalopathy (BSE) in cattle and variant Creutzfeldt–Jakob disease in humans have previously been shown to be caused by the same strain of transmissible spongiform encephalopathy agent. It is hypothesized that the agent spread to humans following consumption of food products prepared from infected cattle. Despite evidence supporting zoonotic transmission, mouse models expressing human prion protein (HuTg) have consistently shown poor transmission rates when inoculated with cattle BSE. Higher rates of transmission have however been observed when these mice are exposed to BSE that has been experimentally transmitted through sheep or goats, indicating that humans may potentially be more susceptible to BSE from small ruminants. Here we demonstrate that increased transmissibility of small ruminant BSE to HuTg mice was not due to replication of higher levels of infectivity in sheep brain tissue, and is instead due to other specific changes in the infectious agent.


2012 ◽  
Vol 117 ◽  
pp. 1-7 ◽  
Author(s):  
Carlos Maluquer de Motes ◽  
Juan-Carlos Espinosa ◽  
Ana Esteban ◽  
Miquel Calvo ◽  
Rosina Girones ◽  
...  

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