Features of the American foreign direct investment: the role of the American holdings

Article is dedicated to the determination of key features of the United States participation in the international capital movement on the example of FDI outflows and inflows, and confirmation of its heterogeneous nature. Tax reform that has been implemented in the end of 2017 led to the result when USA was deleted of the list of TOP-20 world investors of 2018 (by UNCTAD). The scientific opinion and fears were connected with the forecasts that the tax reform could change the movement of FDI flows back to the USA from foreign countries, especially, and the countries with the low taxes and the most favorable investment regimes. At the same time, it needs to underline that the analysis of U.S. FDI inflows and outflows showed that the negative indicator of U.S. FDI outflow (export) in 2018-2019 was connected with the repatriation of U.S. holding companies profits, that were doing business in countries with the most favorable tax and investment regimes. The authors tried to investigate the nature of the American holdings role and the integration of U.S. in to the global system of FDI and capital movement.

Medicolegal Aspects of Victims of Assault Admitted to a Tertiary Care Hospital in Sri Lanka

Introduction: Violence with physical assault is a common cause of morbidity and mortality prevalent but not limited to underdeveloped countries. The opinion of the forensic expert is often indispensable in such cases to determine the penalties. This study was planned to describe the pattern of presentation of the victims and evaluate the strengths and limitations in formulating a scientific medicolegal opinion based on the findings of the victim. Methods: A retrospective descriptive study based on the case records of the victims of assault admitted to Colombo North Teaching Hospital, Ragama, Sri Lanka, was conducted for four years. Results: Out of the 400 victims, the majority (72% n = 290) were males and of the age-group of 21 to 40 (n = 216). The reason for assault in the majority was sudden provocation (n = 99, 25%), followed by previous long-duration enmity (n = 89, 22%). The majority (83%) had isolated blunt force trauma, and the injuries were nongrievous (74%). Defense injuries were significantly associated with attempted defense (p = 0.000) and sharp force trauma (p = 0.002). The underlying reason for the assault was not significantly associated with the causative weapon (p = 0.228) or body region injured (p = 0.195). Conclusions: Even though the presentation and the pattern of injures are definitely of value in formulating a scientific opinion, the study identified the limitations of the forensic experts, and the need for a holistic approach at the investigations was highlighted.

Review of the current and post-Brexit UK legal framework on the regulation of genetic technologies

The launch of a nationwide consultation in January 2021 by the UK Department for the Environment, Food and Rural Affairs (Defra) on the regulation of genetic technologies has been used as an opportunity by the UK Government to gauge public and scientific opinion on the applications of gene editing in agriculture and aquaculture. In particular, the consultation sought to consider the controversial question of whether gene editing (GE) should be subject to the same regulations as genetically modified organisms (GMOs). The distinction between GE and GMO products, as well as between the legal regulations governing them, are highly important: currently, the UK still follows the EU’s restrictive approach, whereby gene editing is regulated in the same way as GMOs. However, in light of the UK’s departure from the EU, the UK government seems willing to reconsider this approach and adopt a new regulatory framework characterised by less stringent controls. Accordingly, this review paper examines the current legal framework on gene editing and GMOs in the UK and EU, as well as in other relevant jurisdictions, before then examining the Defra consultation in light of the mixed responses to it from both the scientific community and the general public. The paper concludes with a number of considerations that should inform any proposed post-Brexit reform of the framework that allows for the correct balance to be struck between scientific development, food security, human health, and the environment.

A Systematic Review on the Effectiveness of Pre-Harvest Meat Safety Interventions in Pig Herds to Control Salmonella and Other Foodborne Pathogens

This systematic review aimed to assess the effectiveness of pre-harvest interventions to control the main foodborne pathogens in pork in the European Union. A total of 1180 studies were retrieved from PubMed® and Web of Science for 15 pathogens identified as relevant in EFSA’s scientific opinion on the public health hazards related to pork (2011). The study selection focused on controlled studies where a cause–effect could be attributed to the interventions tested, and their effectiveness could be inferred. Altogether, 52 studies published from 1983 to 2020 regarding Campylobacter spp., Clostridium perfringens, Methicillin-resistant Staphylococcus aureus, Mycobacterium avium, and Salmonella spp. were retained and analysed. Research was mostly focused on Salmonella (n = 43 studies). In-feed and/or water treatments, and vaccination were the most tested interventions and were, overall, successful. However, the previously agreed criteria for this systematic review excluded other effective interventions to control Salmonella and other pathogens, like Yersinia enterocolitica, which is one of the most relevant biological hazards in pork. Examples of such successful interventions are the Specific Pathogen Free herd principle, stamping out and repopulating with disease-free animals. Research on other pathogens (i.e., Hepatitis E, Trichinella spiralis and Toxoplasma gondii) was scarce, with publications focusing on epidemiology, risk factors and/or observational studies. Overall, high herd health coupled with good management and biosecurity were effective to control or prevent most foodborne pathogens in pork at the pre-harvest level.

Use of Food Additive Titanium Dioxide (E171) before the Introduction of Regulatory Restrictions Due to Concern for Genotoxicity

Food-grade titanium dioxide (TiO2; E171) is a coloring food additive. In May 2021, a scientific opinion was published by the European Food Safety Authority concluding that TiO2 can no longer be considered as a safe food additive. Our aim was to investigate the trends in the use of TiO2 in the food supply. A case study was conducted in Slovenia using two nationally representative cross-sectional datasets of branded foods. Analysis was performed on N = 12,644 foods (6012 and 6632 in 2017 and 2020, respectively) from 15 food subcategories where TiO2 was found as a food additive. A significant decrease was observed in the use of TiO2 (3.6% vs. 1.8%; p < 0.01). TiO2 was most often used in the chewing gum category (36.3%) in 2017, and chocolate and sweets category (45.9%) in 2020. Meanwhile, in 2017, the largest share of TiO2-containing foods was observed in the chewing gum category, namely, 70.3%, and these products presented over 85% of the market share. In 2020, only 24.6% of chewing gums contained TiO2, which accounted for only 3% of the market share. In conclusion, we showed an overall decrease in TiO2 use, even though it has not yet been officially removed from the list of authorized food additives.

Occurrence of Ochratoxin A in Different Types of Cheese Offered for Sale in Italy

The detection of Ochratoxin A (OTA) in the milk of ruminants occurs infrequently and at low levels, but its occurrence may be higher in dairy products such as cheese. The aim of this study was to investigate the presence of OTA in cheeses purchased in the metropolitan city of Bologna (Italy) and the surrounding area. For the analysis, a LC-MS/MS method with a limit of quantification (LOQ) of 1 µg/kg was used. OTA was detected in seven out of 51 samples of grated hard cheese (concentration range 1.3–22.4 µg/kg), while it was not found in the 33 cheeses of other types which were also analysed. These data show a low risk of OTA contamination for almost all types of cheese analysed. To improve the safety of cheese marketed in grated form, more regulations on cheese rind, which is the part most susceptible to OTA-producing moulds, should be implemented or, alternatively, producers should consider not using the rind as row material for grated cheese. It would be interesting to continue these investigations particularly on grated hard cheeses to have more data to update the risk assessment of OTA in cheese, as also suggested by EFSA in its 2020 scientific opinion on OTA.

Use of Food Additive Titanium Dioxide (E171) Before the Introduction of Regulatory Restriction Due to Concern for Genotoxicity

Food additives are used for a variety of technological or processing reasons, including to add or restore colour in a food. In European Union (EU) the safety of food additives was in history assessed by the Scientific Committee on Food, while the role of risk accessor is not in hands of the European Food Safety Authority (EFSA). Only additives for which the proposed uses is considered safe are on the EU list of authorized additives. Very recently – in May 2020, a scientific opinion was published by the EFSA, concluding that TiO2 can no longer be considered as a safe food additive, and the European Commission is expected to remove it from list of authorized food additives in near future. Our aim was to investigate the trends in the use of TiO2 in the food supply. A case study was conducted in Slovenia, using two nationally representative cross-sectional datasets of branded foods. Original sample contained 49,919 pre-packed food items, while analyses was done on N=12.644 foods (6.012 and 6.632 in 2017 and 2020, respectively) from 15 food subcategories, where TiO2 was found as food additive. Overall, we observed significantly decrease in use of TiO2 (3.6% vs. 1.8%; p&lt;0.01) in the course of these three years. The most TiO2-containing foods were in the Chewing gum category (36.3%) in 2017, and Chocolate and sweets (45.9%) in 2020. Meanwhile in 2017 the largest within-category share of TiO2-containing foods was Chewing gum category, namely 70.3%, and those products presented over 85% of the market-share. In 2020 only 24.6% chewing gums contained TiO2, and those were accounting only 3% of the market share. In con-clusion, we showed overall decrease of TiO2 use and considerable improvements in certain food categories (particularly in chewing gums) despite the fact, that this additive has not yet been of-ficially removed from the list of authorized additives. Specific food categories (i.e. Chocolate and sweets) were identified, where product-reformulation is needed, and where official controls by authorities will be most relevant.