scholarly journals Healing the third degree thermal burn in mice by Dielectric Barrier Discharge Plasma (DBD plasma): Comparison and evaluation of area, burn wound healing time, burn skin temperature

10.29007/fmkc ◽  
2020 ◽  
Author(s):  
Thi Minh Hien Ngo ◽  
Tuyet Nhi Do ◽  
Quoc Duy Nam Nguyen ◽  
Duy Phuong Nguyen ◽  
Nguyen Ngan Ha Lam ◽  
...  
Keyword(s):  
Wound Healing ◽  
Healing Time ◽  
Diagnostic Methods ◽  
Invasive Treatment ◽  
Burn Wound ◽  
Dbd Plasma ◽  
Thermal Burn ◽  
Non Invasive ◽  
Burn Wound Healing ◽  
Wound Healing Time

Burns are one of the most devastating conditions encountered in medicine. This injury is in skin or other tissues, caused by heat-cold, electricity or chemicals [1,2]. There are lots of methods to treat burns and each method has its own advantages, such as medicine, dressing, low-level laser, plasma, skin graft surgery... [3].This study experimented with the 3rd degree burn model in mice by heat, treating by DBD plasma, is a non-invasive treatment and using clinical diagnostic methods by (1) normal image, (2) thermal image, (3) HE staining. Aim of this research is evaluation and comparison the area, temperature and wound healing time of non-invasive treatment with DBD plasma and nontreatment. After 3-week experiment, using diagnostic methods and analysis tools have demonstrated that the 3rd thermal burn wound healing of plasma treatment recovers faster than non-treatment about: (1) Burn wound surface shrinkage rate is higher: ~ 5%; (2) Healing time is faster: 2-3 days; (3) The average temperature of the burn wound is lower: 1-2oC. Therefore, DBD plasma is a potential treatment in burns wound and wound healing in the future. Keywords: DBD plasma, burn wound, healing wound

Burn wound healing time assessed by laser Doppler imaging. Part 2: Validation of a dedicated colour code for image interpretation

Burns ◽  
2011 ◽  
Vol 37 (2) ◽  
pp. 249-256 ◽  
Author(s):  
S.M. Monstrey ◽  
H. Hoeksema ◽  
R.D. Baker ◽  
J. Jeng ◽  
R.S. Spence ◽  
...  
Keyword(s):  
Wound Healing ◽  
Image Interpretation ◽  
Healing Time ◽  
Laser Doppler ◽  
Doppler Imaging ◽  
Laser Doppler Imaging ◽  
Burn Wound ◽  
Burn Wound Healing ◽  
Wound Healing Time

scholarly journals The Use of Stem Cells in Burn Wound Healing: A Review

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Fadi Ghieh ◽  
Rosalyn Jurjus ◽  
Amir Ibrahim ◽  
Alice Gerges Geagea ◽  
Hisham Daouk ◽  
...  
Keyword(s):  
Stem Cells ◽  
Wound Healing ◽  
Therapeutic Effect ◽  
Healing Time ◽  
Burn Injuries ◽  
Burn Wound ◽  
Burn Wounds ◽  
Complex Processes ◽  
Burn Wound Healing

Burn wound healing involves a series of complex processes which are subject to intensive investigations to improve the outcomes, in particular, the healing time and the quality of the scar. Burn injuries, especially severe ones, are proving to have devastating effects on the affected patients. Stem cells have been recently applied in the field to promote superior healing of the wounds. Not only have stem cells been shown to promote better and faster healing of the burn wounds, but also they have decreased the inflammation levels with less scar progression and fibrosis. This review aims to highlight the beneficial therapeutic effect of stem cells in burn wound healing and to discuss the involved pathways and signaling molecules. The review covers various types of burn wound healing like skin and corneal burns, along with the alternative recent therapies being studied in the field of burn wound healing. The current reflection of the attitudes of people regarding the use of stem cells in burn wound healing is also stated.

scholarly journals Increased burn healing time is associated with higher Vancouver Scar Scale score

2017 ◽  
Vol 3 ◽  
pp. 205951311769632 ◽  
Author(s):  
Vidya Finlay ◽  
Sally Burrows ◽  
Maddison Burmaz ◽  
Hussna Yawary ◽  
Johanna Lee ◽  
...  
Keyword(s):  
Wound Healing ◽  
Total Body Surface Area ◽  
Likelihood Estimation ◽  
Healing Time ◽  
Burn Wound ◽  
Interaction Terms ◽  
Burn Wound Healing ◽  
Primary Model ◽  
Burn Surgery ◽  
The Relationship

[Formula: see text] Increased burn wound healing time has been shown to influence abnormal scarring. This study hypothesised that scar severity increases commensurate to the increase in time to healing (TTH) of the wound. Wound healing and scar data from burn patients treated by the Burn Service of Western Australia at Royal Perth Hospital were examined. The relationship between TTH and scar severity, as assessed by the modified Vancouver Scar Scale (mVSS), was modelled using regression analysis. Interaction terms evaluated the effect of surgery and total body surface area – burn (TBSA) on the main relationship. Maximum likelihood estimation was used to account for potential bias from missing independent variable data. The sample had a median age of 34 years, TTH of 24 days, TBSA of 3% and length of stay of five days, 70% were men and 71% had burn surgery. For each additional day of TTH, the mVSS score increased by 0.11 points ( P ≤ 0.001) per day in the first 21 days and 0.02 points per day thereafter ( P = 0.004). The relationship remained stable in spite of TBSA or surgical intervention. Investigation of the effect of missing data revealed the primary model underestimated the strength of the association. An increase in TTH within 21 days of injury is associated with an increase in mVSS or reduced scar quality. The results confirm that efforts should be directed toward healing burn wounds as early as possible.

scholarly journals The Effect of Ozone Treatment on Thermal Burn Wound Healing; An Experimental Study

2020 ◽  
Author(s):  
Kemal PEKER ◽  
İsmayil YILMAZ ◽  
İsmail DEMİRYILMAZ ◽  
Arda ISIK ◽  
İlyas SAYAR ◽  
...  
Keyword(s):  
Experimental Study ◽  
Wound Healing ◽  
Ozone Treatment ◽  
Burn Wound ◽  
Thermal Burn ◽  
Burn Wound Healing

(229) Predictors of pain severity after major thermal burn injury vary according to phase of burn wound healing

2015 ◽  
Vol 16 (4) ◽  
pp. S33
Author(s):  
M. Mauck ◽  
A. Liu ◽  
A. Bortsov ◽  
S. Jones ◽  
J. Hwang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Burn Injury ◽  
Pain Severity ◽  
Burn Wound ◽  
Thermal Burn ◽  
Burn Wound Healing

scholarly journals Using invasive and non-invasive methods to evaluate the therapeutic effect of dielectric barrier discharge (DBD) Plasma in skin graft surgery

2021 ◽  
Vol 3 (SI3) ◽  
pp. first
Author(s):  
Ngo Thi Minh Hien ◽  
Do Tuyet Nhi ◽  
Nguyen Quoc Duy Nam ◽  
Vo Duong Van Anh ◽  
Nguyen Duy Phuong ◽  
...  
Keyword(s):  
Wound Healing ◽  
Human Skin ◽  
Skin Graft ◽  
Evaluation Methods ◽  
Healing Time ◽  
The Body ◽  
Therapeutic Effects ◽  
Dbd Plasma ◽  
Dielectric Barrier ◽  
Non Invasive

Skin graft is effective method to reconstruct large lesions on the skin. Long-term injuries such as burns, skin ulcers, skin flaps, skin grafts... can affect the health of the patient. Skin plays a very important role because it protects the body from dehydration, helps regulate temperature, helps prevent pathogenic bacteria or viruses from entering the body and minimizes skin deformation. In recent years the cold plasma has been used to aid the treatment of chronic skin wounds, burns, ulcers,... To assess the effectiveness of the wound healing process of Plasma, this study uses non – invasive (assess the shrinkage of the wound, the temperature change of the wound) and invasive methods (regeneration of skin tissue structure) to evaluate the therapeutic effects of Dielectric Barrier Dissections Plasma (DBD Plasma) in skin graft surgery. Experimenting with the entire skin graft model on mice, this use of DBD Plasma treatment along with clinical evaluation methods, this is to compare wound healing time between wounds treated with plasma DBD and untreated wound. After 21 days of experimentation, evaluation methods and results processing tools, it was shown that wound healing of skin lesions on mice of the wound area treated with DBD Plasma faster than nontreatment about: (1) The surface shrinkage rate is about 25%; (2) The average wound temperature is less than 0.5-1oC; (3) Healing time is faster from 5 to 6 days. Therefore, DBD Plasma is able to be a potential treatment for wound healing combined with skin graft surgery in the future. The initial study of DBD model is the premise from which could be broader in other animals such as rabbits and pigs with skin structure closer to the human skin. And further, the DBD Plasma shows the potential for preclinical application to human skin graft.

PENGGUNAAN SELAPUT AMNION SEGAR PADA INSISI LUKA OPERASI SEKSIO SESAREA

2019 ◽  
Vol 1 (2) ◽  
pp. 47-55
Author(s):  
Syahredi Syaiful Adnani ◽  
Hafni Bachtiar
Keyword(s):  
Wound Healing ◽  
Caesarean Section ◽  
Amniotic Membrane ◽  
Healing Time ◽  
Cost Of Care ◽  
Control Group ◽  
P Value ◽  
Control Groups ◽  
And Control ◽  
Wound Healing Time

In the last few decades, the incidence of caesarean section is increasing in the world, especially in Indonesia. One of the way to treat tissue scar is through biologic and synthetic dressing where nowadays, amnion has been used as biologic dressing frequently. This study was conducted to determine the effect of the use of fresh amniotic membrane on wound incision Caesarean section compared with Caesarean section incision wound covered using regular gauze bandages and fixated with plaster in RS. Dr. Reksodiwiryo Padang. The design of this study is an experimen-tal study with Post test design with control group design. Sampling was done using a formula consecutive sampling two different test samples obtained an average of 72 people for each group. The analysis used include univariate and bivariate analyzes. The average wound healing time the difference was statistically significant (p value <0.05) in the treatment and control groups. There was highly significant difference in the proportion of local infection on day 3 between the treatment and control groups (p value <0.05). There were very significant differences in the proportion of local allergic reactions at day 3, and 5 between the treatment and control group (p <0.05). There are significant differences in terms of the cost of care per day between treatment and control groups (p <0.05). From this study, the average wound healing time has a very significant difference.Keywords: Fresh Amniotic Membrane, Wound Cesarean Section, Wound Healing

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