scholarly journals Omega-3 in the Prevention of Cardiovascular Diseases

2017 ◽  
Vol 5 (10) ◽  
Author(s):  
Martha Izbeth Cerón Sandoval ◽  
Eli Mireya Sandoval Gallegos

In the last years, Mexico has experimented changes in the epidemiological and nutritional transition. There is a decrease of communicable diseases and an increase of chronic diseases, becoming the main causes of death, mainly cardiovascular diseases. Experimental, epidemiological and interventional studies have demonstrated the beneficial cardiovascular effects of eicosapentaenoic acid (EPA) and docosahexanoic acid (DHA), which have antiatherosclerotic, antithrombotic, antiarrhythmic and anti-inflammatory effects. The American Dietetic Association recommend an ingestion of 250 to 1000 mg/day of omega 3. This paper mentions the functional characteristics, biosynthesis and mechanisms of omega-3 fatty acids. This paper also reviews the clinical evidence that support their role as a cardioprotective factor. Derived from the analysis of the reviewed studies, it is concluded that taking into account the benefits of omega-3 fatty acids in the prevention and treatment of cardiovascular diseases, it is necessary to increase the consumption of foods rich in these fatty acids.  

Author(s):  
David Silva ◽  
Maria Paz Villarroel ◽  
Alba L. Roa ◽  
Benita H. Quilodrán

The aim of this work was to evaluate the possibility of using agroindustrial residues as carbon sources for the production of omega-3 polyunsaturated fatty acids by a native Thraustochytrid strain, and analyze the microorganism growth for each substrate. In this study a Chilean strain, Thraustochytrium kinney VAL-B1, was grown in three alternative carbon sources: lupine residue, fermented wine and residual glycerol from biodiesel canola oil for biomass and polyunsaturated fatty acids production. The highest biomass production values were obtained at the fifth day of growth, which were 7.22±0.56 g L-1, 2.72±0.25 g L-1 and 6.54±0.71 g L-1 for fermentations of lupine residue, fermented wine and residual glycerol from biodiesel canola oil, respectively, while the polyunsaturated fatty acids profile showed a docosahexanoic acid percentage of 21.19%, 13.42% and 35.06% in the fermentations of the above mentioned residues. The highest omega 3 fatty acids production (docosahexanoic and eicosapentanoic acid, 2.53±0.36 g L-1 and 0.25±0.03 g L-1, respectively) was obtained in the fermentation of residual glycerol from biodiesel canola oil. With these results, it was concluded that Thraustochytrium kinney VAL-B1 produces more omega 3 fatty acids (docosahexanoic and eicosapentanoic acid) when is fermented in a medium using residual glycerol from biodiesel canola oil as an alternative carbon source, reaching a productivity of 0.50 g L-1 d-1 for docosahexanoic acid. On the other hand, the highest biomass production was obtained in fermentations of lupine residue (7.22 g L-1). For these reasons, it is feasible to employ agroindustrial by-products for polyunsaturated fatty acids production.


The Lancet ◽  
2010 ◽  
Vol 376 (9740) ◽  
pp. 540-550 ◽  
Author(s):  
Palaniappan Saravanan ◽  
Neil C Davidson ◽  
Erik B Schmidt ◽  
Philip C Calder

BMJ ◽  
2010 ◽  
Vol 341 (nov29 1) ◽  
pp. c6273-c6273 ◽  
Author(s):  
P. Galan ◽  
E. Kesse-Guyot ◽  
S. Czernichow ◽  
S. Briancon ◽  
J. Blacher ◽  
...  

Author(s):  
Arif Rahman Hakim

Docosahexanoic acid (DHA) is commercially obtained from marine fish. With an increasinghuman population, the supplies of DHA are still not sufficient to meet the world’s need of DHA asfood supplement. The objective of this review is to discuss Schizochytrium sp., one of microalgaewhich is rich in DHA, as one of the best candidate as producer of sustainable and affordable DHA.Heterotrophic microalgae, especially genus Schizochytrium, produces omega-3 fatty acids up to40% of total unsaturated fatty acids.  Cultivation of the microalgae is easy as it does not requiresunlight as source of energy. Previous publication reported that several local strains ofSchizochytrium have been isolated from mangrove area in Indonesia. We expect that thosestrains can be cultivated in mass production as producer of DHA.


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