scholarly journals THE POTENTIAL OF HETEROTROPHIC MICROALGAE (Schizochytrium sp.) AS A SOURCE OF DHA

Author(s):  
Arif Rahman Hakim

Docosahexanoic acid (DHA) is commercially obtained from marine fish. With an increasinghuman population, the supplies of DHA are still not sufficient to meet the world’s need of DHA asfood supplement. The objective of this review is to discuss Schizochytrium sp., one of microalgaewhich is rich in DHA, as one of the best candidate as producer of sustainable and affordable DHA.Heterotrophic microalgae, especially genus Schizochytrium, produces omega-3 fatty acids up to40% of total unsaturated fatty acids.  Cultivation of the microalgae is easy as it does not requiresunlight as source of energy. Previous publication reported that several local strains ofSchizochytrium have been isolated from mangrove area in Indonesia. We expect that thosestrains can be cultivated in mass production as producer of DHA.

Author(s):  
Maruba Pandiangan ◽  
Jamaran Kaban ◽  
Basuki Wirjosentono ◽  
Jansen Silalahi

Omega 3 and 6 fatty acids are very good consumed to improve human health. For this reason, research is needed to determine the glyceride profile and identification of omega 3 and 6 fatty acids in fat molecules so that the potential of catfish oil as a source of omega 3 and 6 can be known. Catfish oil was extracted by the soxletation method. Fatty acid composition was analyzed by gas chromatography (GC-FID) which was previously esterified using BF3. The results showed that the composition of unsaturated fatty acids more than saturated fatty acids. Omega-3 fatty acids are found consisting of linolenic acid, eicosapentanoic acid (EPA) and docosahexanoic acid (DHA) and omega 6, namely linoleic acid. The comparison of omega 3 and omega 6 in catfish oil is still within the recommended comparison terms. Judging from the composition and position of catfish oil fatty acids which contain omega 3 and omega 6 fatty acids. Thus catfish oil has the potential as a source of omega 3 and 6 from one of the freshwater fish that are consumed by many people.


Author(s):  
Jean-Yves LE GUENNEC ◽  
Forel Céline ◽  
Messager Laureen ◽  
Sierra Camille ◽  
Contreras Ivette ◽  
...  

Up to the middle of the 2000’s, omega 3 polyunsaturated fatty acids were considered has having cardioprotective properties. Patients having a myocardial infarction were supplemented with these fatty acids in secondary prevention of myocardial infarction. Since then, many randomized clinical trials failed to observe the cardioprotective effects previously described. The main hypothesis to explain such change is the systematic prescription of statins to patients following a myocardial infarction, statins interfering with the homeostasis of omega 3 fatty acids. This review discusses the effects of different forms of omega-3 in association with statins on cardiovascular disease and emphasize on the interaction between statins and omega 3 fatty acids leading to the possible need to use higher dose of fatty acids to get a synergistic effect.


2009 ◽  
Vol 2009 ◽  
pp. 112-112
Author(s):  
E Magowan ◽  
A Fearon ◽  
M E E McCann ◽  
A Beattie

The fatty acid profile of pork can be easily manipulated via the diet of the pig. The most common aim is to increase the proportion of unsaturated fatty acids, in particular omega 3 fatty acids. Kim et al. (2008) reported that the breed of pig can have an effect on the fatty acid composition of pork. The aim of the current experiment was to investigate the effect of terminal sires of different breed commonly used in Northern Ireland on the fatty acid profile of pork.


Author(s):  
David Silva ◽  
Maria Paz Villarroel ◽  
Alba L. Roa ◽  
Benita H. Quilodrán

The aim of this work was to evaluate the possibility of using agroindustrial residues as carbon sources for the production of omega-3 polyunsaturated fatty acids by a native Thraustochytrid strain, and analyze the microorganism growth for each substrate. In this study a Chilean strain, Thraustochytrium kinney VAL-B1, was grown in three alternative carbon sources: lupine residue, fermented wine and residual glycerol from biodiesel canola oil for biomass and polyunsaturated fatty acids production. The highest biomass production values were obtained at the fifth day of growth, which were 7.22±0.56 g L-1, 2.72±0.25 g L-1 and 6.54±0.71 g L-1 for fermentations of lupine residue, fermented wine and residual glycerol from biodiesel canola oil, respectively, while the polyunsaturated fatty acids profile showed a docosahexanoic acid percentage of 21.19%, 13.42% and 35.06% in the fermentations of the above mentioned residues. The highest omega 3 fatty acids production (docosahexanoic and eicosapentanoic acid, 2.53±0.36 g L-1 and 0.25±0.03 g L-1, respectively) was obtained in the fermentation of residual glycerol from biodiesel canola oil. With these results, it was concluded that Thraustochytrium kinney VAL-B1 produces more omega 3 fatty acids (docosahexanoic and eicosapentanoic acid) when is fermented in a medium using residual glycerol from biodiesel canola oil as an alternative carbon source, reaching a productivity of 0.50 g L-1 d-1 for docosahexanoic acid. On the other hand, the highest biomass production was obtained in fermentations of lupine residue (7.22 g L-1). For these reasons, it is feasible to employ agroindustrial by-products for polyunsaturated fatty acids production.


2017 ◽  
Vol 5 (10) ◽  
Author(s):  
Martha Izbeth Cerón Sandoval ◽  
Eli Mireya Sandoval Gallegos

In the last years, Mexico has experimented changes in the epidemiological and nutritional transition. There is a decrease of communicable diseases and an increase of chronic diseases, becoming the main causes of death, mainly cardiovascular diseases. Experimental, epidemiological and interventional studies have demonstrated the beneficial cardiovascular effects of eicosapentaenoic acid (EPA) and docosahexanoic acid (DHA), which have antiatherosclerotic, antithrombotic, antiarrhythmic and anti-inflammatory effects. The American Dietetic Association recommend an ingestion of 250 to 1000 mg/day of omega 3. This paper mentions the functional characteristics, biosynthesis and mechanisms of omega-3 fatty acids. This paper also reviews the clinical evidence that support their role as a cardioprotective factor. Derived from the analysis of the reviewed studies, it is concluded that taking into account the benefits of omega-3 fatty acids in the prevention and treatment of cardiovascular diseases, it is necessary to increase the consumption of foods rich in these fatty acids.  


2021 ◽  
Vol 854 (1) ◽  
pp. 012081
Author(s):  
Dragan Sefer ◽  
Stamen Radulovic ◽  
Dejan Peric ◽  
Matija Sefer ◽  
Lazar Makivic ◽  
...  

Abstract Literature data show that the relationship between two groups of polyunsaturated fatty acids in diet, omega 3 acids, whose basic representative is a-linolenic acid (C18: 3 n-3), and omega 6 acids, whose basic representative is linoleic acid (C18: 2 n-6), has a significant role in development of cardiovascular diseases in humans. The optimal ratio of omega 6 to omega 3 fatty acids is around 4:1. In monogastric animals, the fatty acids in feed are absorbed in the gastrointestinal tract largely unchanged. This means the fatty acid profile of the animal’s diet directly reflects the fatty acid profile of the tissue. The daily intake of unsaturated fatty acids can be increased by an adequate animal nutrition strategy. Flaxseed contains ten times more unsaturated (32.26%) than saturated (3.66%) fatty acids. The largest amount of unsaturated fatty acids (about 70%) is a-linolenic acid (ALA), which is a precursor of the entire omega 3 series of fatty acids, and which makes flaxseed an ideal raw material for the production of a wide range of omega 3 enriched products. In order to obtain chicken meat rich in omega 3, an experiment was organized with a specific diet for broilers at fattening. Thanks to the designed animal feed, it was possible to get products (meat, breast, drumstick, liver, subcutaneous fat) with significantly higher amounts of omega 3 fatty acids compared to the same products obtained from broilers fed with conventional mixtures, or with almost the ideal ratio between omega 6 and omega 3 fatty acids.


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