scholarly journals Caracterización clínica e histopatológica de la infección por Papiloma Virus humano de muestras de cérvix. Hospital Teodoro Maldonado Carbo “IESS” // Histopathological and clinical characterization of Human Papilloma Virus infection in cervical samples. Teodoro Maldonado Carbo “IESS”

Ciencia Unemi ◽  
2017 ◽  
Vol 10 (23) ◽  
pp. 105
Author(s):  
César Bedoya ◽  
Sunny Sánchez Giler ◽  
Dolores Zambrano ◽  
Alan Herrera ◽  
Alba Silva ◽  
...  

El Virus del Papiloma Humano (HPV), posee una predilección por los tejidos poliestratificados, con persistencia en capas basales, de allí que a partir de ello es el agente etiológico del cáncer de cérvix, principalmente. Este tipo de cáncer es el segundo más frecuente en mujeres, alrededor del mundo. El HPV es único agente infeccioso oncogénico que lo provoca. Se realizó un trabajo para determinar la prevalencia del virus en mujeres, utilizando técnicas de detección de ADN mediante PCR, en tiempo real, a partir de biopsia de cérvix, además de establecer las características histopatológicas y clínicas relacionadas. La prevalencia fue del 30,67%, la presentación histopatológica más frecuentemente infectada fue el Cáncer de cérvix y el in situ.  Mientras más displásica es la histopatología del cérvix, más frecuente es la presentación del virus. Se demostró una asociación entre la exposición a la infección y la presencia de secreción vaginal blanquecina y la dispareunia. ABSTRACT Human Papilloma Virus (HPV) has a predilection for poly-stratified tissues, with persistence in the basal layers, hence mainly is the etiological agent of cervical cancer. Cervical cancer is the second most common cancer in women worldwide. HPV is unique oncogenic infectious agent that causes it. The objective of the study was to determine the prevalence of the virus in women, using DNA detection techniques through PCR, in real-time, from the cervical biopsy. In addition, the related histopathological and clinical characteristics were established. The prevalence was 30.67%, the most frequently infected histopathology presentation was cervical and in situ cancer. The more dysplastic the histopathology of the cervix, the more frequent the presentation of the virus. An association between exposure to infection and the presence of whitish vaginal discharge and dyspareunia was demonstrated.

2018 ◽  
Vol 19 (9) ◽  
pp. 798-805 ◽  
Author(s):  
Mohd Saeed ◽  
Fawaz D. Alshammari ◽  
Md. Jahoor Alam ◽  
Khan Mohd Sarim ◽  
Khurshid Ahmad ◽  
...  

Author(s):  
I. L. Oboro ◽  
B. P. Athanasius

Aim: To access the level of awareness of cervical cancer screening tools and preventive measures amongst students of a tertiary institution. Methodology: This was a questionnaire-based cross-sectional study. Pre-tested self-administered Questionnaires were distributed to students who were above the age of 18 years in the University of Port Harcourt, Rivers State, Nigeria, to obtain information on their socio-demographics and awareness of cervical cancer, its prevention, risk factors and association with Human Papilloma Virus infection. Information acquired from the questionnaires were presented using descriptive statistics. Chi-Square analysis was used to compare differences between knowledge and practice among the respondents. P-value < 0.05 was considered significant. All tests were carried out with the Epi Info v7 software. Results: A total of 227 students were interviewed.82.8% were female and 22.9% indicated being sexually active. About two-thirds of respondents had some knowledge (heard) of cervical cancer and Pap smear, majority of whom indicated they did so from health care personnel followed closely by the media houses and social media. Only 12.1% were aware of sexual intercourse as a risk factor for Human Papilloma virus infection and about one-fifth knew the currently recommended age for vaccination against the virus. Conclusion: The degree of awareness of cervical cancer in a key population such as the undergraduates sampled in this study is unacceptably low. Increased efforts must therefore be put into public enlightenment as primary prevention of cervical cancer Aim: To access the level of awareness of cervical cancer screening tools and preventive measures amongst students of a tertiary institution. Methodology: This was a questionnaire-based cross-sectional study. Pre-tested self-administered Questionnaires were distributed to students who were above the age of 18 years in the University of Port Harcourt, Rivers State, Nigeria, to obtain information on their socio-demographics and awareness of cervical cancer, its prevention, risk factors and association with Human Papilloma Virus infection. Information acquired from the questionnaires were presented using descriptive statistics. Chi-Square analysis was used to compare differences between knowledge and practice among the respondents. P-value < 0.05 was considered significant. All tests were carried out with the Epi Info v7 software. Results: A total of 227 students were interviewed.82.8% were female and 22.9% indicated being sexually active. About two-thirds of respondents had some knowledge (heard) of cervical cancer and Pap smear, majority of whom indicated they did so from health care personnel followed closely by the media houses and social media. Only 12.1% were aware of sexual intercourse as a risk factor for Human Papilloma virus infection and about one-fifth knew the currently recommended age for vaccination against the virus. Conclusion: The degree of awareness of cervical cancer in a key population such as the undergraduates sampled in this study is unacceptably low. Increased efforts must therefore be put into public enlightenment as primary prevention of cervical cancer


2019 ◽  
Vol 6 (3) ◽  
pp. 881
Author(s):  
Shruthi B. ◽  
Srikanth Goud Mallam ◽  
Manojkumar B. K. ◽  
Dhanalakshmi T. A.

Background: Human papilloma virus infection is responsible for 75-80% of the cervical cancers worldwide. Human papilloma virus infection is a preventable disease, but precaution depends on the cognitive aspects of young women. Authors conducted a study to assess the knowledge, attitude and practices regarding human papilloma virus vaccination and to determine acceptance rate of human papilloma virus vaccination among medical and paramedical students.Methods: Human papilloma virus infection is responsible for 75-80% of the cervical cancers worldwide. Human papilloma virus infection is a preventable disease, but precaution depends on the cognitive aspects of young women. Authors conducted a study to assess the knowledge, attitude and practices regarding human papilloma virus vaccination and to determine acceptance rate of human papilloma virus vaccination among medical and paramedical students.Results: Out of 322 students, 114 medicals (35.4%), 106 pharmacy (32.9%) and 102 nursing students (31.7%) were included in this study. Ninety-one (79.8%) medical students, 64 (60.37%) pharmacy students, 43 (42.1%) nursing students were aware that human papilloma virus can cause cervical cancer. Seventy-three (64.03%) medical students, 64(60.37%) pharmacy students, 40(40.1%) nursing students were aware that there is vaccination for human papilloma virus infection, and it can prevent cervical cancer. Most of the students,78(68.4%) medical students, 57 (53.77%) pharmacy students and 46(45.09%) nursing students believe that more awareness required regarding risk factors of human papilloma virus infection and prevention of cervical cancer. Furthermore, around 66 (57.89%) medical students, 44 (41.05%) pharmacy students, 37(36.27%) nursing students were willing to accept the vaccine for themselves.Conclusions: Majority of the students are lacking knowledge regarding HPV vaccination and cervical cancer prevention with least knowledge among paramedical students. More awareness programmes are required to increase the awareness and acceptability of HPV vaccination.


2017 ◽  
Vol 14 (1) ◽  
pp. 403-410
Author(s):  
P. S Ramapraba ◽  
M. P Chitra ◽  
M PremKumar

Cervical cancer is the second most leading cancer among women. Source of cervical cancer is Human Papilloma Virus (HPV). Tests to confirm a diagnosis of cervical cancer are colposcopy and cervical biopsy (pap smear). This paper includes the usage of colposcopy images and tests to find where cancer cells are on the surface of the cervix. Contourlet transform (CT) is proposed to extract the features of the colposcopy images and then for classification of Aceto white Region (Abnormal) and Non Aceto white Region (Normal), K-Nearest Neighbourhood (KNN) classifier is used. In the existing system, wavelet transforms are used to extract the features in which minimum quantity of information and features are obtained (Only 3 directions are focused). In CT, for higher resolution, additional directional is employed. The greater performance is achieved by extracting and choosing the simplest features from contourlet coefficients of the colposcopy images and these outputs are fed into the KNN classifier for classification.


Oncotarget ◽  
2016 ◽  
Vol 7 (22) ◽  
pp. 31943-31954 ◽  
Author(s):  
Elizabeth Ortiz-Sánchez ◽  
Luz Santiago-López ◽  
Verónica B. Cruz-Domínguez ◽  
Mariel E. Toledo-Guzmán ◽  
Daniel Hernández-Cueto ◽  
...  

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