scholarly journals PATHOMORFOLOGIJA FEATURES OF BLOOD SUPPLY OF SOFT FABRICS OF LOWER LIMBS AT DIABETES MELLITUS

2018 ◽  
Vol 4 ◽  
pp. 20
Author(s):  
�� O. W. �ryzyn�
Keyword(s):  
Diabetes Mellitus ◽  
Blood Supply ◽  
Lower Limbs

Experience of using atraumatic ointment bandages based on peruvian balsam in the complex treatment of patients with chronic wound defects of the lower limbs

2020 ◽  
pp. 43-57
Author(s):  
Anna Tabuika
Keyword(s):  
Diabetes Mellitus ◽  
Staphylococcus Aureus ◽  
Chronic Wounds ◽  
Chronic Wound ◽  
Local Treatment ◽  
Lower Limbs ◽  
Complex Treatment ◽  
Average Area ◽  
Arterial Insufficiency ◽  
Significant Activation

The article reflects the results of a retrospective non-comparative study, the objects of which were 34 outpatient comorbid patients (15 of which are over 60 years old) with chronic wounds of the lower limbs developed against the background of varicosity, post-thrombotic disease, chronic arterial insufficiency of the lower limbs, diabetes mellitus or their combination. Their local treatment was carried out using atraumatic ointment dressing «Branolind N» containing Peruvian balsam. There were 23 women (67.6 %) and 11 men (32.4 %). In microbiological study prior to the beginning of treatment in 31 patients the growth of a pathogen of wound infection was revealed; in 19 patients — Staphylococcus aureus in monoculture and in various associations, in 6 patients — Pseudomonas aeruginosa in monoculture, in other cases — other pathogens. In 3 patients the pathogen was not detected. The average wound size was 34 cm2 . The phase of the wound process was additionally confirmed by cytological studies. After treatment the average area of the wound defect decreased by 10 cm2 and made 24 cm2 on average. Full healing of the wound defect occurred in 11 patients, the others had granulation and active marginal epithelization. There was also a decrease in bacterial semination of wounds, a change in composition of infection agents to less aggressive monoflora, and cytologically — a decrease in signs of inflammation against the background of significant activation of reparative processes.

scholarly journals Study of the influence of vacuum therapy on the wound process in patients with diabetic foot syndrome

2019 ◽  
Vol 74 (4) ◽  
pp. 283-288
Author(s):  
Petr A. Gerasimchuk ◽  
Alexander V. Shidlovskyi ◽  
Dmitriy B. Fira ◽  
Andrey V. Pavlyshyn
Keyword(s):  
Diabetes Mellitus ◽  
Negative Pressure ◽  
Diabetic Foot ◽  
Chronic Wound ◽  
Lower Limbs ◽  
Diabetic Foot Syndrome ◽  
Vacuum Therapy ◽  
Social Significance ◽  
Number Of Patients ◽  
Bed Days

Background: According to the International Diabetes Federation (IDF), the number of patients on diabetes mellitus is now more than 415 million people on Earth, until 2030 it will increase to 439 million, and by 2035 ― will reach 592 million. Throughout life, 4.625% of patients with diabetes mellitus develops a diabetic foot syndrome with the formation of wounds, whose treatment, can not yet be considered satisfactory, since in 1525% of patients are the direct cause of high amputations of the lower limbs. This requires finding new effective methods for treating wound defects in patients with diabetic foot syndrome, one of which can be vacuum wound therapy. Aims: To study the effectiveness of vacuum therapy in the treatment of acute and chronic wound process in patients with diabetic foot syndrome, depending on the pathogenetic form of the lesion. Materials and methods: The effect of vacuum therapy on the course of acute and chronic wound process in 231 patients with neuropathic and ischemic form of diabetic foot syndrome was studied during 20142017. Evaluation of the dynamics of the wound process was carried out on the basis of clinical, planimetric, microbiological, morphological methods, as well as microcirculation indices in the area round the wound. Results: Vacuum therapy of acute and chronic wounds in patients with different pathogenetic forms of diabetic foot syndrome, allows to stabilize the course of wound process, stimulate regenerative processes in the wound, improve local microcirculation (p0.05). This, in turn, allows a shorter time to prepare a wound for closure by one of the methods of plastic surgery or create favorable conditions for its independent epithelization. In patients with ischemic lesions (chronic arterial insufficiency of the third degree), the carrying out of vacuum therapy by standard method leads to an intensification of the pain syndrome. This causes the need to apply an initial negative pressure in the system in the range of 7080 mm Hg, which makes it possible to stop pain during the day. At 23 days of the postoperative period, negative pressure is established at standard values. Conclusions: Vacuum therapy of wounds in patients with diabetic foot syndrome is an effective method of treatment that allows the doctor to reduces the duration of treatment of patients in hospital with a neuropathic form of diabetic foot syndrome on average (4.31.7) bed-days, and patients with ischemic form ― on average (4.11.9) bed-days, which has both medical and social significance.

scholarly journals Caso Clínico: Cirugía Reconstructiva de Tobillo

2018 ◽  
Vol 10 (2) ◽  
pp. 170-174
Author(s):  
Fulvio Enrique Zuñiga Cabrera ◽  
Jaime Santiago Clavijo Jaramillo ◽  
Adriana Abigail Guzmán Villa
Keyword(s):  
Diabetes Mellitus ◽  
Reverse Flow ◽  
Public Health Problem ◽  
Lower Limbs ◽  
World Health ◽  
Major Public Health Problem ◽  
Sural Flap ◽  
Advantages And Disadvantages ◽  
Left Ankle ◽  
Osteosynthesis Material

BACKGROUND: Diabetes mellitus is a major public health problem, according to the World Health Organization, 422 million adults worldwide in 2014. In 2012, it caused 1.5 million deaths worldwide. Diabetes is the leading cause of non-traumatic amputation in lower limbs and foot infections occur with high frequency in poorly controlled patients. This case shows the reconstruction of soft tissue defects in the lower third leg, heel, malleoli and foot through the description of the reverse sural flap. In this study the advantages and disadvantages of the use of this technique are discussed. CASE REPORT: A 56-year-old female patient with a poorly controlled history of Diabetes Mellitus type 2, who suffered a fracture of the left ankle treated with osteosynthesis, and who during the postoperative period attended emergency orthopedics and traumatology, due to severe pain in the left ankle, fever, dehiscence of surgical wound, accompanied by serous secretion. EVOLUTION: The patient, after several surgical cleanings and changes in closure therapy assisted by negative pressure, manages to control the infection, with persistence of the bone coverage defect and the osteosynthesis material. There were additional complications such as joint stiffness, muscle atrophy; it was decided to reconstruct the distal third of the foot using a reverse flow sural fasciocutaneous flap, which evolved satisfactorily, managing to cover the defect with biological tissue. CONCLUSIONS: The sural flap of reverse flow is a reproducible technique that allows to cover coverage defects in the distal third of the leg and ankle; shorten hospitalization times, especially when there is bone exposure or osteosynthesis material.

A Method for Estimating the Degree of Ischemic Damage to the Anatomical Zones of the Lower Limbs from the Parameters of Hemostasis and Blood Supply

2019 ◽  
Vol 53 (2) ◽  
pp. 142-145
Author(s):  
A. V. Bykov ◽  
N. A. Korenevskiy ◽  
G. G. Khubulava ◽  
I. I. Khripina ◽  
S. N. Rodionova
Keyword(s):  
Blood Supply ◽  
Lower Limbs ◽  
Ischemic Damage

scholarly journals THE ROLE OF GLYCATED HEMOGLOBIN IN THE DIAGNOSIS AND IMPROVED PROGNOSIS OF DIABETES MELLITUS

2017 ◽  
pp. 48-53 ◽  
Author(s):  
E. V. Biryukova
Keyword(s):  
Diabetes Mellitus ◽  
Glycated Hemoglobin ◽  
Vascular Complications ◽  
Lower Limbs ◽  
Chronic Hyperglycemia ◽  
Great Vessels ◽  
Hypoglycemic Therapy ◽  
Diagnostic Criterion

The focus on the problem of diabetes mellitus (DM) is associated with the increasing prevalence of the disease and the risk for the development of many vascular complications (nephropathy, retinopathy, lesions of the great vessels of the heart, brain, peripheral vascular disease of the lower limbs), in the development of which chronic hyperglycemia plays a crucial role. In 2011, the WHO decided that glycated hemoglobin (HbA1c) could be used as the diagnostic criterion for diabetes. The role of HbA1c in the choice of hypoglycemic therapy is invaluable. According to the Algorithms of Specialized Medical Care for Diabetes Mellitus Patients, stratification of treatment strategy in patients with newly diagnosed type 2 diabetes is determined by the initial HbA1c.

scholarly journals Leriche Syndrome as a Long-Term Continuum of Vascular Injury: from the Initial Clinical Manifestations to Possible Fatal Outcome (Significance of Interdisciplinary Cooperation Based on Own Clinical Observations)

2020 ◽  
pp. 108-124
Author(s):  
V Rudichenko ◽  
A Kushneryk ◽  
V Reizin
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Erectile Dysfunction ◽  
Strong Predictor ◽  
Psychiatric Morbidity ◽  
Fatal Outcome ◽  
Clinical Manifestations ◽  
Lower Limbs ◽  
Clinical Observations ◽  
Leriche Syndrome

Leriche syndrome typical signs include incapability for erection maintaining, fatigue feeling originating from both lower limbs, bilateral claudication with ischemic pain and lack or reduction of peripheral pulse (starting from femoral segment) combined with paleness or coldness of both lower limbs. The disease commonly affects men, and risk factors include hypertension, diabetes mellitus, hyperlipidemia and smoking. Currently the disorder is referred to type D aortoiliac injuries according to Trans-Atlantic Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II). Data on psychiatric morbidity in Leriche syndrome is scarce. Some publications are dedicated in such a state to depressive disorder and erectile dysfunction, which were observed in psychiatric outpatient department. These may have several reasons, such as obesity, hypertension, diabetes mellitus, hypercholesterolemia and lower urinary tract symptoms. Moreover, erectile dysfunction is believed to be a strong predictor of general and coronary atherosclerosis. Leriche syndrome and penis arteries obstructive disease are considered to be two main reasons of impotence. Other reasons of Leriche syndrome may be lifestyle factors which are common with atherosclerosis: insufficient physical exercises, imbalanced diet and smoking. Statistics on psychiatric morbidity in Leriche syndrome is hard to receive because of multiple risk factors, partially because of atherosclerosis, which is the risk for vascular depression. The article represents historical data about prominent doctors in the history of vascular surgery who touched upon the problems of Leriche syndrome. The authors describe their own clinical observations of acute patient with prolonged development of full clinical manifestation with fatal outcome.

scholarly journals The Influence of Risk Factors on the Choice of Therapeutic Method in Peripheral Arterial Disease

2020 ◽  
Vol 25 (4) ◽  
pp. 31-34
Author(s):  
Oana Stoia ◽  
Ioan Maniţiu ◽  
Ioan Bitea ◽  
Gabriela Eminovici ◽  
Minodora Teodoru
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Peripheral Arterial Disease ◽  
Arterial Disease ◽  
Lower Limbs ◽  
Hospital Treatment ◽  
High Cholesterol ◽  
Factors Associated ◽  
Peripheral Arterial ◽  
Existing Data

Abstract Peripheral arterial disease (PAD) is characterized by obstruction in the lower limbs, mainly due to atherosclerosis. The prevalence of the pathology in people under 40 years of age is 6% and 15-20% in the population over 65 years old.(1,2) Approximately 50% of the affected persons are, at the time of examination, asymptomatic.(3) The most important risk factors associated with this condition are smoking, diabetes mellitus (DM), high cholesterol and high blood pressure (HBP). The current study shows that, regardless of the association of risk factors or pre-hospital treatment, these patients do not benefit from a certain type of treatment (drug or interventional), which corresponds to the existing data in the literature, which do not document the choice of type of treatment depending on the patient’s age or comorbidities.

scholarly journals The frailty syndrome in older adults with type 2 diabetes mellitus and associated factors

2020 ◽  
Vol 23 (1) ◽  
Author(s):  
Bartolomeu Fagundes de Lima Filho ◽  
Antônia Gilvanete Duarte Gama ◽  
Vanessa da Nóbrega Dias ◽  
Eliza Mikaele Tavares da Silva ◽  
Fabricia Azevedo da Costa Cavalcanti ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Older Adults ◽  
Type 2 Diabetes Mellitus ◽  
Logistic Regression ◽  
Logistic Regression Model ◽  
Lower Limbs ◽  
Frailty Syndrome ◽  
Frail Phenotype

Abstract Objective: To compare clinical-functional factors among groups in relation to the frailty syndrome (pre-frail and frail) phenotype profile in older adults with type 2 diabetes mellitus (DM 2). Methods: A descriptive, analytical, cross-sectional study with a quantitative approach was performed. A total of 113 diabetic older adults of both sexes were evaluated in terms of their personal, socio-demographic, clinical-functional, mental, cognitive and fragility phenotype data. The Chi-square test and a logistic regression model were used. Results: The mean age was 68.66±6.62 years, and the sample was mostly female (61.9%), illiterate or with an incomplete primary education (60.2%), pre-frail (52.2%), sedentary (79.6%), and had been diagnosed with DM2 for more than 5 years (58.3%). There was a significant association between “pre-frail and frail” individuals and schooling (p=0.004), social participation (p=0.004), a subjective perception of vision (p=0.004), glycated hemoglobin (p=0.036), limb pain (p=0.012), depressive symptoms (p=0.002) and mobility (p=0.004). The logistic regression model showed an accuracy of 93.6% and the significant variables were education (p=0.039), pain in the lower limbs (p=0.025) and risk of falls (p=0.033). Conclusion: among all the factors related to the “pre-frail” and “frail” phenotype, schooling, pain in the lower limbs and mobility were most related to the worsening of the syndrome and its progress.

scholarly journals Effect of the cream based on Croton lechleri Müll. Arg. in the treatment of diabetic patients' ulcers: a case study

2020 ◽  
Vol 15 (44) ◽  
Author(s):  
Claudete Rempel ◽  
Franciele Dietrich Zagonel ◽  
Daniel Silveira da Silva ◽  
Diorge Jônatas Marmitt ◽  
Eduardo Sehnem
Keyword(s):  
Diabetes Mellitus ◽  
Low Cost ◽  
Lower Limbs ◽  
Diabetic Patients ◽  
Multifactorial Disease ◽  
Potential Complication ◽  
Several Variables ◽  
Therapeutic Alternatives ◽  
Croton Lechleri

Ulcers development in lower limbs is a potential complication known in Diabetes mellitus patients. Conventional medicines frequently do not show desired efficacy, resulting in adverse effects. In this sense, the seek for natural treatments, effective, easy to obtain and handle and at the same time with low cost, becomes a therapeutic alternatives for the ulcers treatment. The aim of this study was to verify the healing potential of a cream made with Croton lechleri Müll.Arg. sap, when applied in diabetic patients ulcers. It is concluded that the cream made with Croton lechleri Müll.Arg. sap showed healing potential, however, several variables should be evaluated and considered simultaneously, since diabetes is a multifactorial disease.

Sign in / Sign up

Export Citation Format

Share Document