scholarly journals BASAL CELL CARCINOMA

2007 ◽  
Vol 14 (02) ◽  
pp. 204-211
Author(s):  
MUHAMMAD FARRUKH AFTAB ◽  
IRFAN AHMAD ◽  
ABDUL MANAN
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Neck Region ◽  
Excision Biopsy ◽  
Skin Defect ◽  
Reconstructive Procedures ◽  
Direct Closure ◽  
Study Results ◽  
One Year

Introduction:- Basal cell carcinoma is the most common skinmalignancy, accounting for about 80% of all skin cancers and may be lethal. Its recognition and management shouldbe familiar to all the general surgeons. Objective:- To describe the prevalence, mode of presentation and varioussurgical options of reconstruction in the management of basal cell carcinoma (BCC) with a local perspective. Setting:-Nishtar Hospital, Multan. Duration:- One year (October 2002 to September 2003). Sample size:- 60 patients. Studydesign:- Descriptive study. Results:- Out of sixty cases, 50 (83%) were male and 10 (17%) were female. Majority ofthe patients presented to us above the age of 45 years and the incidence of BCC increases with the age. The male tofemale ratio was 5:1. Out of 60 cases 26 (20 male, 6 female) 43.3% were farmer, 16 (all male) 26.6% was constructionworkers, 10 (8 male, 2 female) 16.6% were unemployed and 8 (all female) 13.3% were household. No patient presentedbefore 5 years after the development of the lesion. 34 (30 male, 4 female) 56.6% for the last 6-10 years, 20 (16 male,4 female) 33.3% for the last 11-15 years, 2 (all male) 3.3% for 16-20 years and 4 (2 male, 2 female) 6.6% had lesionsfor > 20 years. All the lesions encountered in present study occurred on exposed head and neck region as is evidentfrom the table-III. Most of the patients had the nodular pigmented type of BCC and majority of them were male. Noneof them have Gorlin’s syndrome (Table-IV). Common variant on histopathology was found to be solid type withadenocystic type being the commonest lesion. After the excision of the lesion the skin defect most of the time wasclosed by the mean of split skin graft. Direct closure was done in quarter of the patients. A number of postoperativecomplications were observed after various reconstructive procedures. Wound was found to be commonest complication;with majority of cases getting only minor wound infection. Conclusion:- Delay in presentation has an overall negativeeffect on the outcome. A simple excision, excision biopsy with adequate margin clearance gives surgeon more freedomfor reconstruction.

scholarly journals Incomplete excision of basal cell carcinoma (BCC) in the head and neck region: to wait, or not to wait?

2017 ◽  
Vol 34 (6) ◽  
pp. 607-611 ◽  
Author(s):  
Jakub Miszczyk ◽  
Michał Charytonowicz ◽  
Tomasz Dębski ◽  
Bartłomiej Noszczyk
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Basal Cell ◽  
Neck Region ◽  
Head And Neck Region ◽  
Incomplete Excision

scholarly journals Metastatic Basal Cell Carcinoma: A Biological Continuum of Basal Cell Carcinoma?

2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Karaninder S. Mehta ◽  
Vikram K. Mahajan ◽  
Pushpinder S. Chauhan ◽  
Anju Lath Sharma ◽  
Vikas Sharma ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Neck Region ◽  
Surgical Excision ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Metastatic Basal Cell Carcinoma ◽  
Treat All

Basal cell carcinoma (BCC) accounts for 80% of all nonmelanoma skin cancers. Its metastasis is extremely rare, ranging between 0.0028 and 0.55 of all BCC cases. The usual metastasis to lymph nodes, lungs, bones, or skin is from the primary tumor situated in the head and neck region in nearly 85% cases. A 69-year-old male developed progressively increasing multiple, fleshy, indurated, and at places pigmented noduloulcerative plaques over back, chest, and left axillary area 4 years after wide surgical excision of a pathologically diagnosed basal cell carcinoma. The recurrence was diagnosed as infiltrative BCC and found metastasizing to skin, soft tissue and muscles, and pretracheal and axillary lymph nodes. Three cycles of chemotherapy comprising intravenouscisplatin (50 mg) and 5-florouracil (5-FU, 750 mg) on 2 consecutive days and repeated at every 21 days were effective. As it remains unclear whether metastatic BCC is itself a separate subset of basal cell carcinoma, we feel that early BCC localized at any site perhaps constitutes a biological continuum that may ultimately manifest with metastasis in some individuals and should be evaluated as such. Long-standing BCC is itself potentially at risk of recurrence/dissemination; it is imperative to diagnose and appropriately treat all BCC lesions at the earliest.

Occurrence and recurrence of basal cell carcinoma of the head and neck in negroid and albinoid africans

1987 ◽  
Vol 101 (12) ◽  
pp. 1324-1328 ◽  
Author(s):  
S. A. Ademiluyi ◽  
G. T. A. Ijaduola
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Recurrence Rate ◽  
Basal Cell ◽  
Neck Region ◽  
Head And Neck Region ◽  
Outdoor Workers ◽  
Significant Difference

SummaryA study of sixty patients with basal cell carcinoma of the head and neck region carried out over a six-year period (1979–1985) is hereby presented. Sixteen (26.72 percent) were albinos and 44 (73.28 per cent) negroids. Forty-eight (80 per cent) were outdoor workers. The negroid patients presented between the 3rd and 4th decades while the albinos presented a decade earlier. The commonest site involved in the head and neck was the forehead. The midface showed the highest recurrence rate in both groups, even after adequate excision. The frequency of recurrence in tumours presenting with a size of 2–5 cm. diameter was significantly higher in the albinos than in the negroid (P<0.05), whereas, with tumours of a size larger than 5 cm., there was no statistically significant difference between the albino and the negroid. However, the overall recurrence rate was significantly higher in the albinos (P<0.005). The mortality among the albinos was 25 per cent while there were no deaths in the negroid Africans.

scholarly journals Basal Cell Carcinoma of the Head and Neck Region: An Analysis of 171 Cases

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Omer Sefvan Janjua ◽  
Sana Mehmood Qureshi
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Basal Cell ◽  
Neck Region ◽  
Margin Status ◽  
Anatomical Site ◽  
Female Ratio ◽  
Head And Neck Region ◽  
Malignant Skin Tumors

Objective. To analyze the pattern of presentation of basal cell carcinoma (BCC) and margin status for excised specimens in the head and neck region.Study Design. Retrospective cross-sectional.Duration of Study.January 2009 to December 2011.Methodology. The database of the pathology department was searched to identify records of all malignant skin tumors that underwent standard excision with margins. Out of these records, tumors with a diagnosis of BCC in the head and neck region were retrieved and separated. Age, gender, anatomic location, pattern of tumor, and margin status were noted.Results. A total of 171 cases of BCC from various sites of head and neck were retrieved. Male to female ratio was 1.4 : 1. The age ranged from 22 to 90 years. Seventy-six cases presented on right side, 79 on left, and 16 were in the midline. Most common anatomical site was the nose followed by the cheek. Nodular lesions were the most common (46.2%) followed by pigmented variety (18.7%). Margins were clear in 77 (45.1%) cases, involved in 86 (50.2%) cases, and close in 8 (4.7%) cases.Conclusion. Nose was the most common site followed by the cheek. Nodular and pigmented varieties were the most frequent and margins were involved in more than fifty percent of the cases.

scholarly journals Clinical and Dermoscopic Factors for the Identification of Aggressive Histologic Subtypes of Basal Cell Carcinoma

2021 ◽  
Vol 10 ◽  
Author(s):  
Riccardo Pampena ◽  
Gabriele Parisi ◽  
Mattia Benati ◽  
Stefania Borsari ◽  
Michela Lai ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Multivariate Regression Analysis ◽  
Histologic Subtype ◽  
Logistic Regression Models ◽  
Surgical Recurrence ◽  
Study Results ◽  
Before And After ◽  
Histologic Subtypes

BackgroundInfiltrative basal cell carcinoma (BCC) has a higher risk for post-surgical recurrence as compared to the most common low-aggressive superficial and nodular BCC. Independent diagnostic criteria for infiltrative BCC diagnosis have not been still defined. Improving the pre-surgical recognition of infiltrative BCC might significantly reduce the risk of incomplete excision and recurrence.ObjectiveThe aim of this study is to define clinical and dermoscopic criteria that can differentiate infiltrative BCC from the most common low-aggressive superficial and nodular BCC.MethodsClinical and dermoscopic images of infiltrative, superficial, and nodular BCC were retrospectively retrieved from our database and jointly evaluated by two experienced dermoscopists, blinded for the histologic subtype. Pairwise comparisons between the three histologic subtypes were performed and multivariable logistic regression models were constructed in order to define clinical and dermoscopic factors independently associated with each subtype. To validate our findings, two experienced dermoscopists not previously involved in the study were asked to evaluate clinical and dermoscopic images from an external dataset, guessing the proper BCC subtype between infiltrative, nodular and superficial, before and after being provided with the study results.ResultA total of 481 histopathologically proven BCCs (51.4% nodular, 33.9% superficial, and 14.8% infiltrative) were included. We found that infiltrative BCC mostly appeared on the head and neck as an amelanotic hypopigmented plaque or papule, displaying ulceration on dermoscopic examination, along with arborizing and fine superficial telangiectasia. Shiny white structures were also frequently observed. Multivariate regression analysis allowed us to define a clinical-dermoscopic profile of infiltrative BCC.ConclusionsWe defined the clinical-dermoscopic profile of infiltrative BCC, allowing to differentiate this variant from superficial and nodular BCC. This will improve pre-surgical recognition of infiltrative forms, reducing the risk for post-surgical recurrence.

scholarly journals Cutaneous basal cell carcinoma with endobronchial metastasis

2014 ◽  
Vol 96 (7) ◽  
pp. e20-e21 ◽  
Author(s):  
AH Sadr ◽  
S de Kerviler ◽  
N Kang
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Neck Region ◽  
Rare Tumour ◽  
Head And Neck Region ◽  
Basal Cell Carcinomas ◽  
History Of ◽  
Metastatic Basal Cell Carcinoma ◽  
Common Malignancy

Although basal cell carcinoma is a very common malignancy, metastasis from this tumour is extremely rare. For this reason, many plastic surgeons, dermatologists and physicians dealing with skin malignancies consider this as a locally invasive malignancy. We present a rare case of metastatic basal cell carcinoma manifested as a bronchial tumour. This case highlights the fact that despite basal cell carcinoma’s local invasive potential, the possibility of distant metastasis still exists and clinicians should therefore be cautious about interpreting extracutaneous symptoms. Chest physicians should always consider the possibility of this rare tumour in the lungs in patients with a history of large basal cell carcinomas in the head and neck region.

Pilot epidemiological study of basal cell carcinoma in Melaka

2019 ◽  
Vol 10 (6) ◽  
pp. 18-21
Author(s):  
Samuel D Abishegam ◽  
Azira Mat Yasir ◽  
Ilyasak Hussin ◽  
Izety Shezlinda Noran
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Ethnic Group ◽  
Basal Cell ◽  
Neck Region ◽  
Skin Grafting ◽  
Head And Neck Region ◽  
Plastic And Reconstructive Surgery ◽  
Cutaneous Malignancy ◽  
Local Setting

Background: This study was conceptualized to be a stepping stone for analysis of BCC in Melaka. Aims and Objective: To analyse the incidence of BCC in Melaka and analyse the distribution of age, gender, ethnicity, localization of lesion and treatment done. Materials and Methods: A retrospective analysis on patients who were diagnosed and treated for BCC was conducted in the Department of Plastic and Reconstructive Surgery, Hospital Melaka from January 2013 until March 2019. Result: There were 152 patients diagnosed with BCCs (N=152) involving 80 women (52.6%) and 72 men (47.4%) over the study period. The patients were aged between 18–92 years with average age for women were 66.2 years and 66.1 tears for men. The majority of cases, 134 (88.2%) were located on the head and neck region. The most common ethnic group to be affected by BCC is the Chinese with 78 (51.3%) followed by Malays at 72 (47.4%) and 1 (0.7%) for Indians and 1 (0.7%) for other minor ethnic group. There were 89 (58.6%) patients underwent excision only whilst 63 (41.4%) patients underwent excision with reconstruction either with skin grafting or local flap. Conclusion: Basal cell carcinoma is a common cutaneous malignancy. The local demographics of patients with BCC in Melaka are similar to that in the literature. We hope with the data provided, it will facilitate better outcome treatment of BCC not just in our local setting but elsewhere worldwide.

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